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Li Y. [2]
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期刊论文 [11]
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2020 [11]
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英语 [11]
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Science [11]
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CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation
期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:
Muendlein H.I.
;
Jetton D.
;
Connolly W.M.
;
Eidell K.P.
;
Magri Z.
;
Smirnova I.
;
Poltorak A.
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/28
FLICE inhibitory protein
interleukin 1beta
lipopolysaccharide
messenger RNA
succinate dehydrogenase (ubiquinone)
Casp1 protein, mouse
caspase 8
Cflar protein, mouse
cryopyrin
FLICE inhibitory protein
IL1B protein, mouse
inflammasome
interleukin 1beta
interleukin 1beta converting enzyme
lipopolysaccharide
succinate dehydrogenase (ubiquinone)
cell
enzyme activity
inhibition
maturation
protein
animal cell
animal experiment
Article
bone marrow derived macrophage
cell death
cell protection
complex formation
controlled study
cytokine release
in vitro study
inflammation
mouse
nonhuman
priority journal
protein analysis
protein degradation
protein function
protein interaction
pyroptosis
animal
gene knockdown
genetics
immunology
macrophage
macrophage activation
metabolism
physiology
Murinae
Animals
CASP8 and FADD-Like Apoptosis Regulating Protein
Caspase 1
Caspase 8
Electron Transport Complex II
Gene Knockdown Techniques
Inflammasomes
Interleukin-1beta
Lipopolysaccharides
Macrophage Activation
Macrophages
Mice
NLR Family, Pyrin Domain-Containing 3 Protein
Pyroptosis
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Guthrie L.M.
;
Soma S.
;
Yuan S.
;
Silva A.
;
Zulkifli M.
;
Snavely T.C.
;
Greene H.F.
;
Nunez E.
;
Lynch B.
;
de Ville C.
;
Shanbhag V.
;
Lopez F.R.
;
Acharya A.
;
Petris M.J.
;
Kim B.-E.
;
Gohil V.M.
;
Sacchettini J.C.
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/28
copper
copper zinc superoxide dismutase
cytochrome c oxidase
dopamine beta monooxygenase
elesclomol
monophenol monooxygenase
protein lysine 6 oxidase
copper
cytochrome c oxidase
elesclomol
hydrazine derivative
copper
cytochrome
enzyme
enzyme activity
mitochondrion
mortality
mutation
pathology
rodent
survival
animal cell
animal experiment
animal model
animal tissue
Article
cohort analysis
controlled study
disease severity
drug mechanism
Golgi complex
H9c2(2-1) cell line
in vivo study
male
Menkes syndrome
mitochondrial dynamics
mortality rate
mouse
nerve degeneration
nonhuman
priority journal
secretory pathway
survival rate
animal
brain
cell line
degenerative disease
disease model
drug effect
genetics
knockout mouse
Menkes syndrome
metabolism
mitochondrion
pathology
rat
transport at the cellular level
Murinae
Mus
Animals
Biological Transport
Brain
Cell Line
Copper
Copper Transporter 1
Disease Models, Animal
Electron Transport Complex IV
Hydrazines
Male
Menkes Kinky Hair Syndrome
Mice
Mice, Knockout
Mitochondria
Neurodegenerative Diseases
Rats
PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis
期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:
Wang Q.
;
Boshoff H.I.M.
;
Harrison J.R.
;
Ray P.C.
;
Green S.R.
;
Wyatt P.G.
;
Barry Iii C.E.
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/28
3,3 bis di(methylsulfonyl)propionamide
antiinfective agent
bacterial protein
glucose
glycerol
magnesium
phosphate
propionamide derivative
protein proline proline glutamate
protein proline proline glutamate 51
unclassified drug
amide
bacterial protein
lipid
phthiocerol dimycocerosate
propionamide
thiol derivative
cell component
chemical compound
membrane
mutation
protein
tuberculosis
antibiotic resistance
Article
bacterial cell
bacterial cell wall
bacterial growth
bacterial outer membrane
cell division
drug structure
Mycobacterium tuberculosis
nonhuman
nutrient uptake
priority journal
protein depletion
cell membrane
cell membrane permeability
chemistry
drug effect
gene deletion
genetics
metabolism
transport at the cellular level
Mycobacterium tuberculosis
Amides
Bacterial Proteins
Biological Transport
Cell Membrane
Cell Membrane Permeability
Drug Resistance, Bacterial
Gene Deletion
Glucose
Glycerol
Lipids
Mycobacterium tuberculosis
Sulfhydryl Compounds
Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b
期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:
Weber C.
;
Zhou Y.
;
Lee J.G.
;
Looger L.L.
;
Qian G.
;
Ge C.
;
Capel B.
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/28
STAT3 protein
calcium
histone demethylase
STAT3 protein
embryonic development
gene expression
sex determination
temperature effect
turtle
animal cell
animal experiment
Article
binding site
calcium transport
cell activation
chromatin immunoprecipitation
controlled study
dimerization
Dmrt1 gene
embryo
embryo development
environmental temperature
epigenetic repression
female
gene
gene activation
gene interaction
gene targeting
genetic transcription
gonad
high temperature
immunofluorescence test
Kdm6b gene
male
nonhuman
priority journal
protein phosphorylation
real time polymerase chain reaction
sex determination
signal transduction
temperature dependence
thermoregulation
transcription regulation
upregulation
Western blotting
animal
embryology
gene expression regulation
genetics
metabolism
phosphorylation
sex determination process
temperature
turtle
Reptilia
Trachemys scripta
Trachemys scripta elegans
Animals
Calcium
Female
Gene Expression Regulation, Developmental
Jumonji Domain-Containing Histone Demethylases
Male
Phosphorylation
Sex Determination Processes
STAT3 Transcription Factor
Temperature
Transcription, Genetic
Turtles
Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Bessman N.J.
;
Mathieu J.R.R.
;
Renassia C.
;
Zhou L.
;
Fung T.C.
;
Fernandez K.C.
;
Austin C.
;
Moeller J.B.
;
Zumerle S.
;
Louis S.
;
Vaulont S.
;
Ajami N.J.
;
Sokol H.
;
Putzel G.G.
;
Arvedson T.
;
Sockolow R.E.
;
Lakhal-Littleton S.
;
Cloonan S.M.
;
Arora M.
;
Peyssonnaux C.
;
Sonnenberg G.F.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
ferroportin
hepcidin
iron
cation transport protein
Hamp protein, mouse
hepcidin
iron
metal transporting protein 1
cell
digestive system disorder
immunity
iron
microorganism
animal cell
animal experiment
animal model
animal tissue
Article
controlled study
dendritic cell
enteritis
healing
immunity
intestine flora
intestine injury
iron blood level
iron homeostasis
iron metabolism
iron sequestration
mouse
mucosal healing
mucosal immunity
nonhuman
nutritional immunity
phagocyte
priority journal
protein expression
tissue regeneration
tissue repair
animal
dendritic cell
enteropathy
fecal microbiota transplantation
gene deletion
genetics
homeostasis
intestine mucosa
metabolism
microbiology
mutant mouse strain
physiology
Mus
Animals
Cation Transport Proteins
Dendritic Cells
Fecal Microbiota Transplantation
Gastrointestinal Microbiome
Gene Deletion
Hepcidins
Homeostasis
Intestinal Diseases
Intestinal Mucosa
Iron
Mice
Mice, Mutant Strains
Phagocytes
A central master driver of psychosocial stress responses in the rat
期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:
Kataoka N.
;
Shima Y.
;
Nakajima K.
;
Nakamura K.
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/07/28
vesicular glutamate transporter 1
glutamic acid
Slc17a7 protein, rat
vesicular glutamate transporter 1
brain
homeostasis
physiological response
psychology
rodent
Article
behavioral stress
brain region
emotion
forebrain
homeostasis
human
hypothalamus
in vivo study
innervation
mental stress
nerve cell
nerve tract
nonhuman
optogenetics
priority journal
social defeat
social stress
tenia tecta
thermogenesis
animal
dorsomedial hypothalamic nucleus
female
Long Evans cinnamon rat
male
mental stress
metabolism
physiology
prefrontal cortex
psychosomatic disorder
rat
signal transduction
social behavior
Wistar rat
Rattus
Animals
Dorsomedial Hypothalamic Nucleus
Emotions
Female
Glutamic Acid
Homeostasis
Male
Neurons
Prefrontal Cortex
Prosencephalon
Psychophysiologic Disorders
Rats
Rats, Inbred LEC
Rats, Wistar
Signal Transduction
Social Behavior
Stress, Psychological
Vesicular Glutamate Transport Protein 1
Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance
期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:
Freeman S.A.
;
Uderhardt S.
;
Saric A.
;
Collins R.F.
;
Buckley C.M.
;
Mylvaganam S.
;
Boroumand P.
;
Plumb J.
;
Germain R.N.
;
Ren D.
;
Grinstein S.
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/28
cation channel
chemokine receptor CCR2
chloride
colony stimulating factor 1
epidermal growth factor
epidermal growth factor receptor
lipid
sialoadhesin
sodium ion
tetrandrine
two pore channel
unclassified drug
calcium channel
lipid
Mcoln1 protein, mouse
sodium
TPCN1 protein, mouse
TPCN2 protein, mouse
transient receptor potential channel
cation
homeostasis
immune system
protein
recycling
animal experiment
Article
bone marrow derived macrophage
cell vacuole
cell volume
channel gating
chloride transport
concentration (parameter)
controlled study
endocytosis
extracellular fluid
extracellular space
homeostasis
human
human cell
human tissue
immunosurveillance
in vitro study
internalization
ion current
knockout mouse
macropinocytosis
mouse
nonhuman
priority journal
protein stability
RNA interference
sodium transport
tonoplast
animal
cell organelle
endosome
genetics
immunology
ion transport
macrophage
metabolism
osmosis
physiology
pinocytosis
Animals
Calcium Channels
Endosomes
Immunologic Surveillance
Ion Transport
Lipids
Macrophages
Mice
Mice, Knockout
Organelles
Osmosis
Pinocytosis
Sodium
Transient Receptor Potential Channels
Vacuoles
Structural insights into immunoglobulin M
期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:
Li Y.
;
Wang G.
;
Li N.
;
Wang Y.
;
Zhu Q.
;
Chu H.
;
Wu W.
;
Tan Y.
;
Yu F.
;
Su X.-D.
;
Gao N.
;
Xiao J.
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/28
immunoglobulin M
secretory component
antibody
immunity
molecular analysis
polymer
protein
Article
binding site
conformational transition
cryoelectron microscopy
crystal structure
human
hydrophobicity
nonhuman
oligomerization
priority journal
protein assembly
protein domain
protein function
protein interaction
protein stability
protein structure
protein transport
surface area
An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors
期刊论文
, 2020, 卷号: 367, 期号: 6476
作者:
Reinhard K.
;
Rengstl B.
;
Oehm P.
;
Michel K.
;
Billmeier A.
;
Hayduk N.
;
Klein O.
;
Kuna K.
;
Ouchan Y.
;
Wöll S.
;
Christ E.
;
Weber D.
;
Suchan M.
;
Bukur T.
;
Birtel M.
;
Jahndel V.
;
Mroz K.
;
Hobohm K.
;
Kranz L.
;
Diken M.
;
Kühlcke K.
;
Türeci Ö.
;
Sahin U.
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/07/28
chimeric antigen receptor
claudin 6
RNA vaccine
antigen
cell component
protein
RNA
tumor
vaccine
animal cell
animal experiment
animal model
animal tissue
antigen presenting cell
antineoplastic activity
Article
cell stimulation
cell transport
chimeric antigen receptor T-cell immunotherapy
controlled study
drug efficacy
human
human cell
in vivo study
mouse
nonhuman
phenotype
priority journal
real time polymerase chain reaction
solid malignant neoplasm
therapy effect
vaccination coverage
Ion transport and regulation in a synaptic vesicle glutamate transporter
期刊论文
, 2020, 卷号: 368, 期号: 6493
作者:
Li F.
;
Eriksen J.
;
Finer-Moore J.
;
Chang R.
;
Nguyen P.
;
Bowen A.
;
Myasnikov A.
;
Yu Z.
;
Bulkley D.
;
Cheng Y.
;
Edwards R.H.
;
Stroud R.M.
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/28
brain
chemical binding
chloride
neurology
substrate
Rattus
chloride
chloride channel
glutamic acid
Slc17a6 protein, rat
vesicular glutamate transporter 2
allosterism
amino acid sequence
animal
binding site
chemistry
cryoelectron microscopy
ion transport
membrane potential
metabolism
pH
protein domain
rat
synapse vesicle
Allosteric Regulation
Amino Acid Sequence
Animals
Binding Sites
Chloride Channels
Chlorides
Cryoelectron Microscopy
Glutamic Acid
Hydrogen-Ion Concentration
Ion Transport
Membrane Potentials
Protein Domains
Rats
Synaptic Vesicles
Vesicular Glutamate Transport Protein 2