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| Structure elucidation of the elusive Enzyme I monomer reveals the molecular mechanisms linking oligomerization and enzymatic activity 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 20 作者: Nguyen T.T.; Ghirlando R.; Roche J.; Venditti V. 收藏  |  浏览/下载:17/0  |  提交时间:2021/11/25 |
| Biological signal processing filters via engineering allosteric transcription factors 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 46 作者: Groseclose T.M.; Hersey A.N.; Huang B.D.; Realff M.J.; Wilson C.J. 收藏  |  浏览/下载:15/0  |  提交时间:2022/02/22 |
| A nanobody activating metabotropic glutamate receptor 4 discriminates between homo- And heterodimers 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 33 作者: Haubrich J.; Font J.; Quast R.B.; Goupil-Lamy A.; Scholler P.; Nevoltris D.; Acher F.; Chames P.; Rondard P.; Prézeau L.; Pin J.-P. 收藏  |  浏览/下载:20/0  |  提交时间:2022/02/22 |
| Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity 期刊论文 Science, 2021, 卷号: 373, 期号: 6555 作者: Gobeil S.M.-C.; Janowska K.; McDowell S.; Mansouri K.; Parks R.; Stalls V.; Kopp M.F.; Manne K.; Li D.; Wiehe K.; Saunders K.O.; Edwards R.J.; Korber B.; Haynes B.F.; Henderson R.; Acharya P. 收藏  |  浏览/下载:27/0  |  提交时间:2022/01/14 |
| Double inhibition and activation mechanisms of Ephexin family RhoGEFs 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 8 作者: Zhang M.; Lin L.; Wang C.; Zhu J. 收藏  |  浏览/下载:0/0  |  提交时间:2021/05/24 |
| The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 117, 期号: 52 作者: Hoj J.P.; Mayro B.; Pendergast A.M. 收藏  |  浏览/下载:10/0  |  提交时间:2021/05/24 |
| The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 12 作者: Leth-Espensen K.Z.; Kristensen K.K.; Kumari A.; Winther A.-M.L.; Young S.G.; Jørgensen T.J.D.; Ploug M. 收藏  |  浏览/下载:26/0  |  提交时间:2021/05/24 |
| Cadherin cis and trans interactions are mutually cooperative 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 10 作者: Thompson C.J.; Vu V.H.; Leckband D.E.; Schwartz D.K. 收藏  |  浏览/下载:32/0  |  提交时间:2021/05/24 |
| Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 12 作者: Moghadamchargari Z.; Shirzadeh M.; Liu C.; Schrecke S.; Packianathan C.; Russell D.H.; Zhao M.; Laganowsky A. 收藏  |  浏览/下载:23/0  |  提交时间:2021/05/24 |
| Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR 期刊论文 , 2020, 卷号: 367, 期号: 6480 作者: Wingler L.M.; Skiba M.A.; McMahon C.; Staus D.P.; Kleinhenz A.L.W.; Suomivuori C.-M.; Latorraca N.R.; Dror R.O.; Lefkowitz R.J.; Kruse A.C. 收藏  |  浏览/下载:23/0  |  提交时间:2020/07/28 angiotensin 1 receptor beta arrestin G protein coupled receptor biochemistry crystal chemistry crystal structure physiological response protein signaling allosterism alpha helix amino terminal sequence Article binding affinity binding site carboxy terminal sequence conformational transition crystallization hydrogen bond molecular dynamics priority journal protein binding protein conformation protein protein interaction protein stability signal transduction thermostability |