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Pharmacological inhibition of MDA-9/Syntenin blocks breast cancer metastasis through suppression of IL-1β 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 21
作者:  Pradhan A.K.;  Maji S.;  Bhoopathi P.;  Talukdar S.;  Mannangatti P.;  Guo C.;  Wang X.-Y.;  Cartagena L.C.;  Idowu M.;  Landry J.W.;  Sarkar D.;  Emdad L.;  Cavenee W.K.;  Das S.K.;  Fisher P.B.
收藏  |  浏览/下载:127/0  |  提交时间:2022/02/22
Agonist of growth hormone–releasing hormone enhances retinal ganglion cell protection induced by macrophages after optic nerve injury 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 28
作者:  Cen L.-P.;  Ng T.K.;  Liang J.-J.;  Xu C.;  Zhuang X.;  Liu Y.-F.;  Chen S.-L.;  Xu Y.;  Yang Q.;  Yuan X.-L.;  Qin Y.J.;  Chan S.O.;  Chen H.;  Zhang M.;  Schally A.V.;  Pang C.P.
收藏  |  浏览/下载:29/0  |  提交时间:2022/02/22
HIV proviral DNA integration can drive T cell growth ex vivo 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 117, 期号: 52
作者:  Yoon J.K.;  Holloway J.R.;  Wells D.W.;  Kaku M.;  Jetton D.;  Brown R.;  Coffin J.M.
收藏  |  浏览/下载:24/0  |  提交时间:2021/05/24
Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 2
作者:  Cui L.;  Moraga I.;  Lerbs T.;  van Neste C.;  Wilmes S.;  Tsutsumi N.;  Trotman-Grant A.C.;  Gakovic M.;  Andrews S.;  Gotlib J.;  Darmanis S.;  Enge M.;  Quake S.;  Hitchcock I.S.;  Piehler J.;  Christopher Garcia K.;  Wernig G.
收藏  |  浏览/下载:31/0  |  提交时间:2021/05/24
Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b 期刊论文
Science, 2020, 卷号: 368, 期号: 6488
作者:  Weber C.;  Zhou Y.;  Lee J.G.;  Looger L.L.;  Qian G.;  Ge C.;  Capel B.
收藏  |  浏览/下载:22/0  |  提交时间:2022/01/14
Computing cancer's weak spots 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Khamsi R.
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/28
ruxolitinib  STAT3 protein  antineoplastic agent  transcription factor  algorithm  cancer  computer simulation  disease treatment  drug development  medicine  Article  cancer cell  cancer radiotherapy  enzyme inhibition  gene activity  gene expression regulation  gene interaction  gene mutation  gene repression  gene targeting  human  laboratory test  malignant neoplasm  molecular dynamics  nonhuman  oncologist  priority journal  RNA sequencing  algorithm  genetics  mutation  neoplasm  personalized medicine  procedures  systems biology  Algorithms  Antineoplastic Agents  Humans  Mutation  Neoplasms  Precision Medicine  Systems Biology  Transcription Factors  
Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b 期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:  Weber C.;  Zhou Y.;  Lee J.G.;  Looger L.L.;  Qian G.;  Ge C.;  Capel B.
收藏  |  浏览/下载:23/0  |  提交时间:2020/07/28
STAT3 protein  calcium  histone demethylase  STAT3 protein  embryonic development  gene expression  sex determination  temperature effect  turtle  animal cell  animal experiment  Article  binding site  calcium transport  cell activation  chromatin immunoprecipitation  controlled study  dimerization  Dmrt1 gene  embryo  embryo development  environmental temperature  epigenetic repression  female  gene  gene activation  gene interaction  gene targeting  genetic transcription  gonad  high temperature  immunofluorescence test  Kdm6b gene  male  nonhuman  priority journal  protein phosphorylation  real time polymerase chain reaction  sex determination  signal transduction  temperature dependence  thermoregulation  transcription regulation  upregulation  Western blotting  animal  embryology  gene expression regulation  genetics  metabolism  phosphorylation  sex determination process  temperature  turtle  Reptilia  Trachemys scripta  Trachemys scripta elegans  Animals  Calcium  Female  Gene Expression Regulation, Developmental  Jumonji Domain-Containing Histone Demethylases  Male  Phosphorylation  Sex Determination Processes  STAT3 Transcription Factor  Temperature  Transcription, Genetic  Turtles  
Interleukin-13 drives metabolic conditioning of muscle to endurance exercise 期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:  Knudsen N.H.;  Stanya K.J.;  Hyde A.L.;  Chalom M.M.;  Alexander R.K.;  Liou Y.-H.;  Starost K.A.;  Gangl M.R.;  Jacobi D.;  Liu S.;  Sopariwala D.H.;  Fonseca-Pereira D.;  Li J.;  Hu F.B.;  Garrett W.S.;  Narkar V.A.;  Ortlund E.A.;  Kim J.H.;  Paton C.M.;  Cooper J.A.;  Lee C.-H.
收藏  |  浏览/下载:42/0  |  提交时间:2020/07/28
glucose  interleukin 13  interleukin 13 receptor alpha1  interleukin 6  STAT3 protein  fatty acid  glycogen  interleukin 13  interleukin 13 receptor alpha1  STAT3 protein  Stat3 protein, mouse  fatty acid  metabolism  muscle  oxidation  physiological response  protein  respiration  aerobic exercise  animal cell  animal experiment  animal tissue  Article  C2C12 cell line  cohort analysis  controlled study  endurance training  energy metabolism  ex vivo study  exercise intensity  female  gastrocnemius muscle  glucose tolerance  human  in vitro study  male  mitochondrial biogenesis  mitochondrial dynamics  mitochondrial respiration  mouse  muscle metabolism  muscle mitochondrion  nonhuman  obesity  priority journal  protein blood level  protein expression  running  sedentary lifestyle  signal transduction  treadmill exercise  adaptation  animal  blood  C57BL mouse  cell line  endurance  genetics  glucose blood level  immunology  knockout mouse  metabolism  myoblast  oxidation reduction reaction  skeletal muscle  Mus  Adaptation, Physiological  Animals  Blood Glucose  Cell Line  Fatty Acids  Female  Glycogen  Humans  Interleukin-13  Interleukin-13 Receptor alpha1 Subunit  Male  Mice  Mice, Inbred C57BL  Mice, Knockout  Mitochondria, Muscle  Muscle, Skeletal  Myoblasts  Oxidation-Reduction  Physical Conditioning, Animal  Physical Endurance  Running  STAT3 Transcription Factor  
An environment-dependent transcriptional network specifies human microglia identity 期刊论文
Science, 2017, 卷号: 356, 期号: 6344
作者:  Gosselin D.;  Skola D.;  Coufal N.G.;  Holtman I.R.;  Schlachetzki J.C.M.;  Sajti E.;  Jaeger B.N.;  O'Connor C.;  Fitzpatrick C.;  Pasillas M.P.;  Pena M.;  Adair A.;  Gonda D.D.;  Levy M.L.;  Ransohoff R.M.;  Gage F.H.;  Glass C.K.
收藏  |  浏览/下载:12/0  |  提交时间:2022/01/14