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| Pharmacological inhibition of MDA-9/Syntenin blocks breast cancer metastasis through suppression of IL-1β 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 21 作者: Pradhan A.K.; Maji S.; Bhoopathi P.; Talukdar S.; Mannangatti P.; Guo C.; Wang X.-Y.; Cartagena L.C.; Idowu M.; Landry J.W.; Sarkar D.; Emdad L.; Cavenee W.K.; Das S.K.; Fisher P.B. 收藏  |  浏览/下载:127/0  |  提交时间:2022/02/22 |
| Agonist of growth hormone–releasing hormone enhances retinal ganglion cell protection induced by macrophages after optic nerve injury 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 28 作者: Cen L.-P.; Ng T.K.; Liang J.-J.; Xu C.; Zhuang X.; Liu Y.-F.; Chen S.-L.; Xu Y.; Yang Q.; Yuan X.-L.; Qin Y.J.; Chan S.O.; Chen H.; Zhang M.; Schally A.V.; Pang C.P. 收藏  |  浏览/下载:29/0  |  提交时间:2022/02/22 |
| HIV proviral DNA integration can drive T cell growth ex vivo 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 117, 期号: 52 作者: Yoon J.K.; Holloway J.R.; Wells D.W.; Kaku M.; Jetton D.; Brown R.; Coffin J.M. 收藏  |  浏览/下载:24/0  |  提交时间:2021/05/24 |
| Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 2 作者: Cui L.; Moraga I.; Lerbs T.; van Neste C.; Wilmes S.; Tsutsumi N.; Trotman-Grant A.C.; Gakovic M.; Andrews S.; Gotlib J.; Darmanis S.; Enge M.; Quake S.; Hitchcock I.S.; Piehler J.; Christopher Garcia K.; Wernig G. 收藏  |  浏览/下载:31/0  |  提交时间:2021/05/24 |
| Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b 期刊论文 Science, 2020, 卷号: 368, 期号: 6488 作者: Weber C.; Zhou Y.; Lee J.G.; Looger L.L.; Qian G.; Ge C.; Capel B. 收藏  |  浏览/下载:22/0  |  提交时间:2022/01/14 |
| Computing cancer's weak spots 期刊论文 , 2020, 卷号: 368, 期号: 6496 作者: Khamsi R. 收藏  |  浏览/下载:32/0  |  提交时间:2020/07/28 ruxolitinib STAT3 protein antineoplastic agent transcription factor algorithm cancer computer simulation disease treatment drug development medicine Article cancer cell cancer radiotherapy enzyme inhibition gene activity gene expression regulation gene interaction gene mutation gene repression gene targeting human laboratory test malignant neoplasm molecular dynamics nonhuman oncologist priority journal RNA sequencing algorithm genetics mutation neoplasm personalized medicine procedures systems biology Algorithms Antineoplastic Agents Humans Mutation Neoplasms Precision Medicine Systems Biology Transcription Factors |
| Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b 期刊论文 , 2020, 卷号: 368, 期号: 6488 作者: Weber C.; Zhou Y.; Lee J.G.; Looger L.L.; Qian G.; Ge C.; Capel B. 收藏  |  浏览/下载:23/0  |  提交时间:2020/07/28 STAT3 protein calcium histone demethylase STAT3 protein embryonic development gene expression sex determination temperature effect turtle animal cell animal experiment Article binding site calcium transport cell activation chromatin immunoprecipitation controlled study dimerization Dmrt1 gene embryo embryo development environmental temperature epigenetic repression female gene gene activation gene interaction gene targeting genetic transcription gonad high temperature immunofluorescence test Kdm6b gene male nonhuman priority journal protein phosphorylation real time polymerase chain reaction sex determination signal transduction temperature dependence thermoregulation transcription regulation upregulation Western blotting animal embryology gene expression regulation genetics metabolism phosphorylation sex determination process temperature turtle Reptilia Trachemys scripta Trachemys scripta elegans Animals Calcium Female Gene Expression Regulation, Developmental Jumonji Domain-Containing Histone Demethylases Male Phosphorylation Sex Determination Processes STAT3 Transcription Factor Temperature Transcription, Genetic Turtles |
| Interleukin-13 drives metabolic conditioning of muscle to endurance exercise 期刊论文 , 2020, 卷号: 368, 期号: 6490 作者: Knudsen N.H.; Stanya K.J.; Hyde A.L.; Chalom M.M.; Alexander R.K.; Liou Y.-H.; Starost K.A.; Gangl M.R.; Jacobi D.; Liu S.; Sopariwala D.H.; Fonseca-Pereira D.; Li J.; Hu F.B.; Garrett W.S.; Narkar V.A.; Ortlund E.A.; Kim J.H.; Paton C.M.; Cooper J.A.; Lee C.-H. 收藏  |  浏览/下载:42/0  |  提交时间:2020/07/28 glucose interleukin 13 interleukin 13 receptor alpha1 interleukin 6 STAT3 protein fatty acid glycogen interleukin 13 interleukin 13 receptor alpha1 STAT3 protein Stat3 protein, mouse fatty acid metabolism muscle oxidation physiological response protein respiration aerobic exercise animal cell animal experiment animal tissue Article C2C12 cell line cohort analysis controlled study endurance training energy metabolism ex vivo study exercise intensity female gastrocnemius muscle glucose tolerance human in vitro study male mitochondrial biogenesis mitochondrial dynamics mitochondrial respiration mouse muscle metabolism muscle mitochondrion nonhuman obesity priority journal protein blood level protein expression running sedentary lifestyle signal transduction treadmill exercise adaptation animal blood C57BL mouse cell line endurance genetics glucose blood level immunology knockout mouse metabolism myoblast oxidation reduction reaction skeletal muscle Mus Adaptation, Physiological Animals Blood Glucose Cell Line Fatty Acids Female Glycogen Humans Interleukin-13 Interleukin-13 Receptor alpha1 Subunit Male Mice Mice, Inbred C57BL Mice, Knockout Mitochondria, Muscle Muscle, Skeletal Myoblasts Oxidation-Reduction Physical Conditioning, Animal Physical Endurance Running STAT3 Transcription Factor |
| An environment-dependent transcriptional network specifies human microglia identity 期刊论文 Science, 2017, 卷号: 356, 期号: 6344 作者: Gosselin D.; Skola D.; Coufal N.G.; Holtman I.R.; Schlachetzki J.C.M.; Sajti E.; Jaeger B.N.; O'Connor C.; Fitzpatrick C.; Pasillas M.P.; Pena M.; Adair A.; Gonda D.D.; Levy M.L.; Ransohoff R.M.; Gage F.H.; Glass C.K. 收藏  |  浏览/下载:12/0  |  提交时间:2022/01/14 |