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期刊论文 [20]
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2020 [20]
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英语 [20]
来源机构
Science [20]
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Circadian rhythms in the absence of the clock gene Bmal1
期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:
Ray S.
;
Valekunja U.K.
;
Stangherlin A.
;
Howell S.A.
;
Snijders A.P.
;
Damodaran G.
;
Reddy A.B.
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/28
phosphoproteome
proteome
transcription factor ARNTL
transcription factor Ets
transcriptome
unclassified drug
cell component
circadian rhythm
gene
gene expression
genome
molecular analysis
animal experiment
animal tissue
Article
Bmal1 gene
circadian rhythm
controlled study
gene deletion
gene expression regulation
gene function
gene knockout
genotype
knockout mouse
light dark cycle
liver
mouse
nonhuman
oscillation
oxidation reduction potential
priority journal
RNA sequence
skin fibroblast
temperature
transcription regulation
Mammalia
Mus
The Ccr4-Not complex monitors the translating ribosome for codon optimality
期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:
Buschauer R.
;
Matsuo Y.
;
Sugiyama T.
;
Chen Y.-H.
;
Alhusaini N.
;
Sweet T.
;
Ikeuchi K.
;
Cheng J.
;
Matsuki Y.
;
Nobuta R.
;
Gilmozzi A.
;
Berninghausen O.
;
Tesina P.
;
Becker T.
;
Coller J.
;
Inada T.
;
Beckmann R.
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/28
exonuclease
initiation factor 5A
messenger RNA
ribosome RNA
transfer RNA
ubiquitin protein ligase E3
bioassay
biomonitoring
cell component
plant and fungus structure and form
40S ribosomal subunit
adenylation
amino terminal sequence
Article
binding site
biochemical analysis
carbon catabolite repressor 4 negative on tata complex
codon
complex formation
controlled study
cryoelectron microscopy
homeostasis
molecular interaction
nonhuman
priority journal
protein conformation
ribosome
Saccharomyces cerevisiae
sequence analysis
ubiquitination
Saccharomyces cerevisiae
Liquid-liquid phase separation drives skin barrier formation
期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:
Quiroz F.G.
;
Fiore V.F.
;
Levorse J.
;
Polak L.
;
Wong E.
;
Pasolli H.A.
;
Fuchs E.
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/28
filaggrin
keratohyalin
coalescence
differentiation
separation
skin
skin disorder
stratification
amino acid composition
Article
bioengineering
biophysics
cell differentiation
cell function
cell structure
epidermis cell
genetic transfection
human
keratinocyte
liquid
live cell imaging
molecular dynamics
nonhuman
pH
phase separation
phase transition
priority journal
proteomics
sequence analysis
signal transduction
skin
skin surface
Mus
Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:
Martin E.W.
;
Holehouse A.S.
;
Peran I.
;
Farag M.
;
Incicco J.J.
;
Bremer A.
;
Grace C.R.
;
Soranno A.
;
Pappu R.V.
;
Mittag T.
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/28
aromatic hydrocarbon
biophysics
concentration (composition)
genetic analysis
nuclear magnetic resonance
prion disease
protein
separation
temperature effect
article
nonhuman
nuclear magnetic resonance spectroscopy
phase separation
prediction
prion
simulation
X ray crystallography
amino acid sequence
chemistry
phase transition
prion
protein domain
small angle scattering
X ray diffraction
heterogeneous nuclear ribonucleoprotein A1
phenylalanine
tyrosine
Amino Acid Sequence
Heterogeneous Nuclear Ribonucleoprotein A1
Magnetic Resonance Spectroscopy
Phase Transition
Phenylalanine
Prions
Protein Domains
Scattering, Small Angle
Tyrosine
X-Ray Diffraction
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Lepack A.E.
;
Werner C.T.
;
Stewart A.F.
;
Fulton S.L.
;
Zhong P.
;
Farrelly L.A.
;
Smith A.C.W.
;
Ramakrishnan A.
;
Lyu Y.
;
Bastle R.M.
;
Martin J.A.
;
Mitra S.
;
O'Connor R.M.
;
Wang Z.-J.
;
Molina H.
;
Turecki G.
;
Shen L.
;
Yan Z.
;
Calipari E.S.
;
Dietz D.M.
;
Kenny P.J.
;
Maze I.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
amidase
dopamine
histone H3
histone transamidase
protein glutamine gamma glutamyltransferase 2
RNA
unclassified drug
brain
cell
chemical compound
chemical reaction
gene expression
genetic analysis
protein
action potential
amino acid substitution
amino terminal sequence
Article
cocaine dependence
controlled study
dopamine release
dopaminergic nerve cell
dopaminergic transmission
down regulation
drug seeking behavior
enzyme activity
gene expression
histone dopaminylation
histone modification
human
human tissue
hyperpolarization
in vitro study
motivation
nerve cell plasticity
nerve projection
neuropathology
nucleus accumbens
priority journal
protein expression
protein function
reward
RNA sequence
ventral tegmentum
Rattus
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis
期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:
Ebright R.Y.
;
Lee S.
;
Wittner B.S.
;
Niederhoffer K.L.
;
Nicholson B.T.
;
Bardia A.
;
Truesdell S.
;
Wiley D.F.
;
Wesley B.
;
Li S.
;
Mai A.
;
Aceto N.
;
Vincent-Jordan N.
;
Szabolcs A.
;
Chirn B.
;
Kreuzer J.
;
Comaills V.
;
Kalinich M.
;
Haas W.
;
Ting D.T.
;
Toner M.
;
Vasudevan S.
;
Haber D.A.
;
Maheswaran S.
;
Micalizzi D.S.
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/28
CRISPR associated protein
epidermal growth factor receptor 2
Ki 67 antigen
ribosome protein
ribosome RNA
transcription factor E2F
ribosome protein
cancer
cell
gene expression
genetic engineering
protein
RNA
tumor
animal experiment
animal model
animal tissue
Article
biogenesis
bioluminescence
breast cancer
cell cycle progression
cell cycle regulation
cell proliferation
circulating tumor cell
controlled study
enzyme activation
epithelial mesenchymal transition
gene expression profiling
genetic transcription
human
human cell
lung metastasis
metastasis
microfluidics
mouse
nonhuman
overall survival
phenotype
priority journal
progression free survival
promoter region
protein expression
protein processing
protein synthesis
proteomics
RNA sequence
transcription regulation
animal
breast tumor
cancer transplantation
CRISPR Cas system
female
gene expression regulation
genetics
pathology
sequence analysis
tumor cell line
tumor embolism
Mus
Animals
Breast Neoplasms
Cell Line, Tumor
CRISPR-Cas Systems
Female
Gene Expression Regulation, Neoplastic
Humans
Mice
Neoplasm Metastasis
Neoplasm Transplantation
Neoplastic Cells, Circulating
Ribosomal Proteins
Sequence Analysis, RNA
Structure of nucleosome-bound human BAF complex
期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:
He S.
;
Wu Z.
;
Tian Y.
;
Yu Z.
;
Yu J.
;
Wang X.
;
Li J.
;
Liu B.
;
Xu Y.
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/28
actin related protein
adenosine triphosphatase
BRG1 BRM associated factor
DNA
multiprotein complex
protein SWI
retinoblastoma binding protein 2
SMARCC protein
SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily B member 1
transcription factor
transcription factor SNF
unclassified drug
cancer
enzyme activity
gene expression
hydrolysis
mutation
protein
alpha helix
Article
carboxy terminal sequence
cell interaction
cryoelectron microscopy
disease association
human
malignant neoplasm
molecular recognition
mutation
nucleosome
priority journal
protein function
protein hydrolysis
protein structure
structure analysis
Mammalia
Massively multiplex chemical transcriptomics at single-cell resolution
期刊论文
, 2020, 卷号: 367, 期号: 6473
作者:
Srivatsan S.R.
;
McFaline-Figueroa J.L.
;
Ramani V.
;
Saunders L.
;
Cao J.
;
Packer J.
;
Pliner H.A.
;
Jackson D.L.
;
Daza R.M.
;
Christiansen L.
;
Zhang F.
;
Steemers F.
;
Shendure J.
;
Trapnell C.
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/28
4 (2 aminoethylamino) 1,8 dimethylimidazo[1,2 a]quinoxaline
abexinostat
acetic acid
belinostat
cudc 101
fimepinostat
givinostat
histone deacetylase inhibitor
m 344
n [2 [3 (1 piperazinylmethyl)imidazo[2,1 b]thiazol 6 yl]phenyl] 2 quinoxalinecarboxamide
panobinostat
pracinostat
rec 2282
trametinib
transcriptome
trichostatin A
unclassified drug
transcriptome
cancer
cell
chemical analysis
detection method
experimental study
genetic analysis
resolution
A-549 cell line
animal cell
animal experiment
Article
cell function
cell heterogeneity
cell labeling
cell proliferation
chromatin
controlled study
dose response
drug activity
experimentation
gene control
genetic transcription
human
human cell
K-562 cell line
MCF-7 cell line
mouse
nonhuman
pilot study
priority journal
proof of concept
RNA sequence
screening
single cell analysis
transcriptomics
cell nucleus
drug effect
genetics
genomics
high throughput screening
metabolism
neoplasm
procedures
single cell analysis
A549 Cells
Acetates
Cell Nucleus
Chromatin
Genomics
High-Throughput Screening Assays
Histone Deacetylase Inhibitors
Humans
K562 Cells
MCF-7 Cells
Neoplasms
RNA-Seq
Single-Cell Analysis
Transcriptome
TTC5 mediates autoregulation of tubulin via mRNA degradation
期刊论文
, 2020, 卷号: 367, 期号: 6473
作者:
Lin Z.
;
Gasic I.
;
Chandrasekaran V.
;
Peters N.
;
Shao S.
;
Mitchison T.J.
;
Hegde R.S.
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/28
messenger RNA
mutant protein
polypeptide
recombinant protein
regulator protein
tetratricopeptide protein 5
tubulin
unclassified drug
biodegradation
chromosome
peptide
protein
RNA
amino terminal sequence
animal cell
Article
autoregulation
binding site
chromosome segregation
controlled study
cryoelectron microscopy
genetic code
human
human cell
Leporidae
mitosis
molecular model
nonhuman
priority journal
protein analysis
protein binding
protein interaction
protein structure
reticulocyte
ribosome
RNA degradation
RNA translation
tubulin gene
Regenerative potential of prostate luminal cells revealed by single-cell analysis
期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:
Karthaus W.R.
;
Hofree M.
;
Choi D.
;
Linton E.L.
;
Turkekul M.
;
Bejnood A.
;
Carver B.
;
Gopalan A.
;
Abida W.
;
Laudone V.
;
Biton M.
;
Chaudhary O.
;
Xu T.
;
Masilionis I.
;
Manova K.
;
Mazutis L.
;
Pe’er D.
;
Regev A.
;
Sawyers C.L.
收藏
  |  
浏览/下载:116/0
  |  
提交时间:2020/07/28
androgen
growth factor
Nrg2 growth factor
Rspo3 growth factor
unclassified drug
androgen binding protein
antiandrogen
ataxin 1
Atxn1 protein, mouse
glycosylphosphatidylinositol anchored protein
homeodomain protein
nerve growth factor
Nkx3-1 protein, mouse
Nrg2 protein, mouse
probasin
Psca protein, mouse
R-spondin3 protein, mouse
thrombospondin
transcription factor
tumor antigen
tumor protein
androgen
cancer
cell
gene expression
RNA
rodent
ablation therapy
animal cell
animal tissue
Article
cell differentiation
cell population
cell regeneration
cells by body anatomy
controlled study
gene
gene expression
human
luminal cell
male
mesenchyme cell
mouse
nonhuman
paracrine signaling
priority journal
prostate cell
prostate tissue
protein expression
Psca gene
RNA sequencing
Sca1 gene
single cell analysis
animal
genetics
mesenchymal stem cell
metabolism
organ size
organoid
physiology
prostate
prostate tumor
regeneration
sequence analysis
single cell analysis
Mus
Androgen Antagonists
Androgen-Binding Protein
Androgens
Animals
Antigens, Neoplasm
Ataxin-1
Cell Differentiation
Gene Expression
GPI-Linked Proteins
Homeodomain Proteins
Humans
Male
Mesenchymal Stem Cells
Mice
Neoplasm Proteins
Nerve Growth Factors
Organ Size
Organoids
Prostate
Prostatic Neoplasms
Regeneration
Sequence Analysis, RNA
Single-Cell Analysis
Thrombospondins
Transcription Factors