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| Trait dimensions in bacteria and archaea compared to vascular plants 期刊论文
Ecology Letters, 2021, 卷号: 24, 期号: 7
作者: Westoby M.; Gillings M.R.; Madin J.S.; Nielsen D.A.; Paulsen I.T.; Tetu S.G.
  收藏 | 浏览/下载：27/0 | 提交时间：2021/09/01
archaea bacteria cell radial diameter ecological strategies genome size maximum growth rate plants rRNA operon copy number signal transduction proteins trait ecology |
| Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者: Wilmes S.; Hafer M.; Vuorio J.; Tucker J.A.; Winkelmann H.; Löchte S.; Stanly T.A.; Pulgar Prieto K.D.; Poojari C.; Sharma V.; Richter C.P.; Kurre R.; Hubbard S.R.; Christopher Garcia K.; Moraga I.; Vattulainen I.; Hitchcock I.S.; Piehler J.
收藏 | 浏览/下载：47/0 | 提交时间：2020/07/28
cytokine receptor homodimer Janus kinase 2 ligand oncoprotein cancer enzyme enzyme activity membrane molecular analysis mutation protein activation analysis Article cell membrane computer model controlled study dimerization fluorescence microscopy gene mutation HeLa cell line molecular dynamics mutant oncogene priority journal protein domain protein interaction quantitative analysis signal transduction |
| Temporal integration of mitogen history in mother cells controls proliferation of daughter cells 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者: Min M.; Rong Y.; Tian C.; Spencer S.L.
收藏 | 浏览/下载：29/0 | 提交时间：2020/07/28
cyclin D mitogen activated protein kinase kinase mitogenic agent cell cycle G1 phase cell cycle G2 phase cell proliferation genetics human metabolism physiology protein synthesis signal transduction stem cell Cell Proliferation Cyclin D G1 Phase G2 Phase Humans Mitogen-Activated Protein Kinase Kinases Mitogens Protein Biosynthesis Signal Transduction Stem Cells |
| Bose polarons near quantum criticality 期刊论文
, 2020, 卷号: 368, 期号: 6487
作者: Yan Z.Z.; Ni Y.; Robens C.; Zwierlein M.W.
收藏 | 浏览/下载：31/0 | 提交时间：2020/07/28
physics quantum mechanics spectroscopy article critical temperature radiofrequency spectroscopy signal transduction |
| Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b 期刊论文
, 2020, 卷号: 368, 期号: 6488
作者: Weber C.; Zhou Y.; Lee J.G.; Looger L.L.; Qian G.; Ge C.; Capel B.
收藏 | 浏览/下载：35/0 | 提交时间：2020/07/28
STAT3 protein calcium histone demethylase STAT3 protein embryonic development gene expression sex determination temperature effect turtle animal cell animal experiment Article binding site calcium transport cell activation chromatin immunoprecipitation controlled study dimerization Dmrt1 gene embryo embryo development environmental temperature epigenetic repression female gene gene activation gene interaction gene targeting genetic transcription gonad high temperature immunofluorescence test Kdm6b gene male nonhuman priority journal protein phosphorylation real time polymerase chain reaction sex determination signal transduction temperature dependence thermoregulation transcription regulation upregulation Western blotting animal embryology gene expression regulation genetics metabolism phosphorylation sex determination process temperature turtle Reptilia Trachemys scripta Trachemys scripta elegans Animals Calcium Female Gene Expression Regulation, Developmental Jumonji Domain-Containing Histone Demethylases Male Phosphorylation Sex Determination Processes STAT3 Transcription Factor Temperature Transcription, Genetic Turtles |
| Liquid-liquid phase separation drives skin barrier formation 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者: Quiroz F.G.; Fiore V.F.; Levorse J.; Polak L.; Wong E.; Pasolli H.A.; Fuchs E.
收藏 | 浏览/下载：31/0 | 提交时间：2020/07/28
filaggrin keratohyalin coalescence differentiation separation skin skin disorder stratification amino acid composition Article bioengineering biophysics cell differentiation cell function cell structure epidermis cell genetic transfection human keratinocyte liquid live cell imaging molecular dynamics nonhuman pH phase separation phase transition priority journal proteomics sequence analysis signal transduction skin skin surface Mus |
| Microglia monitor and protect neuronal function through specialized somatic purinergic junctions 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者: Cserép C.; Pósfai B.; Lénárt N.; Fekete R.; László Z.I.; Lele Z.; Orsolits B.; Molnár G.; Heindl S.; Schwarcz A.D.; Ujvári K.; Környei Z.; Tóth K.; Szabadits E.; Sperlágh B.; Baranyi M.; Csiba L.; Hortobágyi T.; Maglóczky Z.; Martinecz B.; Szabó G.; Erdélyi F.; Szipocs R.; Tamkun M.M.; Gesierich B.; Duering M.; Katona I.; Liesz A.; Tamás G.; Dénes Á.
收藏 | 浏览/下载：40/0 | 提交时间：2020/07/28
calcium purinergic P2Y12 receptor brain cell component homeostasis inhibition protein animal cell Article brain injury controlled study functional connectivity human human cell microglia mitochondrion mouse nerve cell neuroprotection nonhuman perikaryon priority journal signal transduction somatic microglia neuron junction |
| Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain 期刊论文
, 2020, 卷号: 369, 期号: 6500
作者: Horowitz A.M.; Fan X.; Bieri G.; Smith L.K.; Sanchez-Diaz C.I.; Schroer A.B.; Gontier G.; Casaletto K.B.; Kramer J.H.; Williams K.E.; Villeda S.A.
收藏 | 浏览/下载：33/0 | 提交时间：2020/07/28
glycosylphosphatidylinositol glycosylphosphatidylinositol phospholipase D phospholipase D aging animal animal experiment blood brain circulation cognition cognitive defect enzymology liver metabolism mouse nervous system development pathophysiology physiology regeneration signal transduction vascularization Aging Animals Blood Circulation Brain Cognition Cognitive Dysfunction Glycosylphosphatidylinositols Liver Mice Neurogenesis Phospholipase D Physical Conditioning, Animal Regeneration Signal Transduction |
| Structural basis of Gs and Gi recognition by the human glucagon receptor 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者: Qiao A.; Han S.; Li X.; Li Z.; Zhao P.; Dai A.; Chang R.; Tai L.; Tan Q.; Chu X.; Ma L.; Thorsen T.S.; Reedtz-Runge S.; Yang D.; Wang M.-W.; Sexton P.M.; Wootten D.; Sun F.; Zhao Q.; Wu B.
收藏 | 浏览/下载：43/0 | 提交时间：2020/07/28
cyclic AMP glucagon glucagon receptor inhibitory guanine nucleotide binding protein stimulatory guanine nucleotide binding protein glucagon receptor inhibitory guanine nucleotide binding protein protein binding stimulatory guanine nucleotide binding protein chemical binding enzyme activity gene expression mutagenicity protein alpha helix Article binding affinity carboxy terminal sequence conformational transition cryoelectron microscopy human molecular recognition mutagenesis priority journal protein binding protein function protein protein interaction protein structure signal transduction binding site chemistry metabolism molecular model protein conformation ultrastructure Binding Sites Cryoelectron Microscopy Glucagon GTP-Binding Protein alpha Subunits, Gi-Go GTP-Binding Protein alpha Subunits, Gs Humans Models, Molecular Protein Binding Protein Conformation Protein Conformation, alpha-Helical Receptors, Glucagon Signal Transduction |
| Dopamine promotes cognitive effort by biasing the benefits versus costs of cognitive work 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者: Westbrook A.; van den Bosch R.; Määttä J.I.; Hofmans L.; Papadopetraki D.; Cools R.; Frank M.J.
收藏 | 浏览/下载：27/0 | 提交时间：2020/07/28
dopamine dopamine 2 receptor methylphenidate sulpiride dopamine dopamine 2 receptor blocking agent dopamine uptake inhibitor brain cost-benefit analysis decision making hormone sampling adult Article cognition cost benefit analysis decision making dopamine metabolism female gaze human human experiment male memory consolidation motivation normal human priority journal receptor blocking striate cortex task performance adolescent biosynthesis caudate nucleus cognition corpus striatum drug effect eye fixation memory metabolism reward saccadic eye movement signal transduction young adult Adolescent Caudate Nucleus Choice Behavior Cognition Corpus Striatum Decision Making Dopamine Dopamine D2 Receptor Antagonists Dopamine Uptake Inhibitors Female Fixation, Ocular Humans Male Memory Methylphenidate Motivation Reward Saccades Signal Transduction Sulpiride Young Adult |
