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An Endophytic Strain of Bacillus amyloliquefaciens Suppresses Fusarium oxysporum Infection of Chinese Wolfberry by Altering Its Rhizosphere Bacterial Community 期刊论文
FRONTIERS IN MICROBIOLOGY, 2022, 卷号: 12
作者:  Uwaremwe, Constantine;  Yue, Liang;  Wang, Yun;  Tian, Yuan;  Zhao, Xia;  Liu, Yang;  Zhou, Qin;  Zhang, Yubao;  Wang, Ruoyu
收藏  |  浏览/下载：101/0  |  提交时间：2022/04/28
GROWTH-PROMOTING RHIZOBACTERIA  MICROBIAL COMMUNITIES  BIOLOGICAL-CONTROL  BIOCONTROL AGENTS  COMMON SCAB  WILT  SUBTILIS  CUCUMBER  IDENTIFICATION  INCREASES  
Tiny 2D silicon quantum sheets: a brain photonic nanoagent for orthotopic glioma theranostics 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 2
作者:  Miao Z.;  Hu D.;  Gao D.;  Fan L.;  Ma Y.;  Ma T.;  Liu X.;  Zheng H.;  Zha Z.;  Sheng Z.;  Xu C.-Y.
收藏  |  浏览/下载：28/0  |  提交时间：2021/09/01
Orthotopic glioma  Photoacoustic imaging  Photothermal therapy  Theranostic agents  Two-dimensional (2D) silicon  
Rational Construction of Fluorescence Turn-Off Fluorinated Carbon Fiber/Ag Composites and Their Anticancer and Antibacterial Activities 期刊论文
ACS APPLIED BIO MATERIALS, 2021, 卷号: 4, 期号: 2
作者:  Wang, Dandan;  Peng, Jingyi;  Huang, Yan;  Sun, Lu;  Liu, Mingyue;  Li, Hui;  Chao, Mianran;  Gong, Peiwei;  Liu, Zhe;  You, Jinmao
收藏  |  浏览/下载：27/0  |  提交时间：2022/04/28
TARGETED DRUG-DELIVERY  GRAPHENE OXIDE  NANOPARTICLES  PHOTOLUMINESCENCE  AGENTS  
Current strategies for the development of fluorescence-based molecular probes for visualizing the enzymes and proteins associated with Alzheimer's disease 期刊论文
COORDINATION CHEMISTRY REVIEWS, 2021, 卷号: 427
作者:  Ma, Siyue;  Chen, Guang;  Xu, Jie;  Liu, Yuxia;  Li, Guoliang;  Chen, Tao;  Li, Yulin;  James, Tony D.
收藏  |  浏览/下载：20/0  |  提交时间：2022/04/28
IN-VIVO DETECTION  BETA-AMYLOID PLAQUES  METHIONINE SULFOXIDE REDUCTASES  MONOAMINE-OXIDASE-B  IMAGING AGENTS  LIVING CELLS  BENZOTHIAZOLE DERIVATIVES  NEUROFIBRILLARY TANGLES  BENZOFURAN DERIVATIVES  SELECTIVE DETECTION  
Recent progress in the development of chemodosimeters for fluorescence visualization of phosgene 期刊论文
DYES AND PIGMENTS, 2021, 卷号: 193
作者:  Tan, Jiangkun;  Li, Zan;  Lu, Zhihao;  Chang, Rui;  Sun, Zhiwei;  You, Jinmao
收藏  |  浏览/下载：20/0  |  提交时间：2022/04/28
CHEMICAL WARFARE AGENTS  DUAL-CHANNEL DISCRIMINATION  SELECTIVE DETECTION  RATIOMETRIC CHEMODOSIMETER  DETECTING PHOSGENE  VISUAL DETECTION  PROBE  ESIPT  CHEMOSENSOR  CARBON  
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Dai W.;  Zhang B.;  Jiang X.-M.;  Su H.;  Li J.;  Zhao Y.;  Xie X.;  Jin Z.;  Peng J.;  Liu F.;  Li C.;  Li Y.;  Bai F.;  Wang H.;  Cheng X.;  Cen X.;  Hu S.;  Yang X.;  Wang J.;  Liu X.;  Xiao G.;  Jiang H.;  Rao Z.;  Zhang L.-K.;  Xu Y.;  Yang H.;  Liu H.
收藏  |  浏览/下载：36/0  |  提交时间：2020/07/28
aldehyde  antimicrobial activity  drug  enzyme activity  infectivity  inhibitor  reaction kinetics  viral disease  Coronavirus  SARS coronavirus  3C-like proteinase, Coronavirus  antivirus agent  cysteine proteinase  viral protein  animal  Betacoronavirus  chemical structure  chemistry  Chlorocebus aethiops  Coronavirus infection  dog  drug design  drug effect  enzyme active site  enzymology  female  human  male  mouse  pandemic  preclinical study  protein tertiary structure  Sprague Dawley rat  toxicity testing  Vero cell line  virus pneumonia  Animals  Antiviral Agents  Betacoronavirus  Catalytic Domain  Chlorocebus aethiops  Coronavirus Infections  Cysteine Endopeptidases  Dogs  Drug Design  Drug Evaluation, Preclinical  Female  Humans  Male  Mice  Molecular Structure  Pandemics  Pneumonia, Viral  Protein Structure, Tertiary  Rats, Sprague-Dawley  Toxicity Tests  Vero Cells  Viral Nonstructural Proteins  
Computing cancer's weak spots 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Khamsi R.
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/28
ruxolitinib  STAT3 protein  antineoplastic agent  transcription factor  algorithm  cancer  computer simulation  disease treatment  drug development  medicine  Article  cancer cell  cancer radiotherapy  enzyme inhibition  gene activity  gene expression regulation  gene interaction  gene mutation  gene repression  gene targeting  human  laboratory test  malignant neoplasm  molecular dynamics  nonhuman  oncologist  priority journal  RNA sequencing  algorithm  genetics  mutation  neoplasm  personalized medicine  procedures  systems biology  Algorithms  Antineoplastic Agents  Humans  Mutation  Neoplasms  Precision Medicine  Systems Biology  Transcription Factors  
Structure of the RNA-dependent RNA polymerase from COVID-19 virus 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Gao Y.;  Yan L.;  Huang Y.;  Liu F.;  Zhao Y.;  Cao L.;  Wang T.;  Sun Q.;  Ming Z.;  Zhang L.;  Ge J.;  Zheng L.;  Zhang Y.;  Wang H.;  Zhu Y.;  Zhu C.;  Hu T.;  Hua T.;  Zhang B.;  Yang X.;  Li J.;  Yang H.;  Liu Z.;  Xu W.;  Guddat L.W.;  Wang Q.;  Lou Z.;  Rao Z.
收藏  |  浏览/下载：38/0  |  提交时间：2020/07/28
comparative study  drug  electron microscopy  enzyme  enzyme activity  RNA  virus  Coronavirus  SARS coronavirus  adenosine phosphate  alanine  antivirus agent  NSP7 protein, SARS-CoV-2  NSP8 protein, SARS-CoV-2  remdesivir  RNA directed RNA polymerase  RNA-dependent RNA polymerase, coronavirus  viral protein  beta sheet  Betacoronavirus  chemistry  cryoelectron microscopy  drug design  enzyme active site  enzymology  metabolism  molecular model  protein domain  ultrastructure  Adenosine Monophosphate  Alanine  Antiviral Agents  Betacoronavirus  Catalytic Domain  Cryoelectron Microscopy  Drug Design  Models, Molecular  Protein Conformation, beta-Strand  Protein Domains  RNA Replicase  Viral Nonstructural Proteins  
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文
, 2020, 卷号: 368, 期号: 6498
作者:  Yin W.;  Mao C.;  Luan X.;  Shen D.-D.;  Shen Q.;  Su H.;  Wang X.;  Zhou F.;  Zhao W.;  Gao M.;  Chang S.;  Xie Y.-C.;  Tian G.;  Jiang H.-W.;  Tao S.-C.;  Shen J.;  Jiang Y.;  Jiang H.;  Xu Y.;  Zhang S.;  Zhang Y.;  Xu H.E.
收藏  |  浏览/下载：110/0  |  提交时间：2020/07/28
adenosine phosphate  alanine  antivirus agent  enzyme inhibitor  multiprotein complex  NSP7 protein, SARS-CoV-2  NSP8 protein, SARS-CoV-2  remdesivir  RNA directed RNA polymerase  RNA-dependent RNA polymerase, coronavirus  viral protein  virus RNA  Betacoronavirus  chemistry  cryoelectron microscopy  drug effect  enzyme active site  enzymology  metabolism  molecular model  physiology  protein conformation  virus replication  Adenosine Monophosphate  Alanine  Antiviral Agents  Betacoronavirus  Catalytic Domain  Cryoelectron Microscopy  Enzyme Inhibitors  Models, Molecular  Multiprotein Complexes  Protein Conformation  RNA Replicase  RNA, Viral  Viral Nonstructural Proteins  Virus Replication  
Effect of tolerance on the evolution of antibiotic resistance under drug combinations 期刊论文
, 2020, 卷号: 367, 期号: 6474
作者:  Liu J.;  Gefen O.;  Ronin I.;  Bar-Meir M.;  Balaban N.Q.
收藏  |  浏览/下载：12/0  |  提交时间：2020/07/28
daptomycin  rifampicin  vancomycin  antiinfective agent  beta' subunit of RNA polymerase  daptomycin  DNA directed RNA polymerase  rifampicin  vancomycin  antibiotic resistance  bacterium  emergence  evolutionary biology  experimental study  laboratory method  survival  adult  antibiotic resistance  Article  bacterial mutation  bacterial strain  bacterium isolation  clinical article  colony forming unit  combination drug therapy  drug effect  drug tolerance  human  in vitro study  minimum inhibitory concentration  nonhuman  phylogeny  priority journal  Staphylococcus aureus  whole genome sequencing  antibiotic resistance  combination drug therapy  drug effect  genetics  methicillin resistant Staphylococcus aureus  microbial sensitivity test  microbiology  molecular evolution  mutation  single nucleotide polymorphism  Staphylococcus infection  Staphylococcus aureus  Anti-Bacterial Agents  Daptomycin  DNA-Directed RNA Polymerases  Drug Resistance, Microbial  Drug Therapy, Combination  Evolution, Molecular  Humans  Methicillin-Resistant Staphylococcus aureus  Microbial Sensitivity Tests  Mutation  Polymorphism, Single Nucleotide  Rifampin  Staphylococcal Infections  Vancomycin