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| Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 29
作者: Dampalla C.S.; Zheng J.; Perera K.D.; Wong L.-Y.R.; Meyerholz D.K.; Nguyen H.N.; Kashipathy M.M.; Battaile K.P.; Lovell S.; Kim Y.; Perlman S.; Groutas W.C.; Chang K.-O.
  收藏 | 浏览/下载：27/0 | 提交时间：2021/11/25 |
| Orthogonal genome-wide screens of bat cells identify MTHFD1 as a target of broad antiviral therapy 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 39
作者: Anderson D.E.; Cui J.; Ye Q.; Huang B.; Tan Y.; Jiang C.; Zu W.; Gong J.; Liu W.; Kim S.Y.; Yan B.G.; Sigmundsson K.; Lim X.F.; Ye F.; Niu P.; Irving A.T.; Zhang H.; Tang Y.; Zhou X.; Wang Y.; Tan W.; Wang L.-F.; Tan X.
收藏 | 浏览/下载：43/0 | 提交时间：2021/11/25 |
| Protease cleavage of RNF20 facilitates coronavirus replication via stabilization of SREBP1 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 37
作者: Zhang S.; Wang J.; Cheng G.
收藏 | 浏览/下载：7/0 | 提交时间：2022/02/22 |
| Generation of sars-cov-2 reporter replicon for high-throughput antiviral screening and testing 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 15
作者: He X.; Quan S.; Xu M.; Rodriguez S.; Goh S.L.; Wei J.; Fridman A.; Koeplinger K.A.; Carroll S.S.; Grobler J.A.; Espeseth A.S.; Olsen D.B.; Hazuda D.J.; Wang D.
收藏 | 浏览/下载：27/0 | 提交时间：2021/05/24 |
| In silico dynamics of COVID-19 phenotypes for optimizing clinical management 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 3
作者: Voutouri C.; Nikmaneshi M.R.; Corey Hardin C.; Patel A.B.; Verma A.; Khandekar M.J.; Dutta S.; Stylianopoulos T.; Munn L.L.; Jain R.K.
收藏 | 浏览/下载：75/0 | 提交时间：2021/05/24 |
| Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 5
作者: Jan J.-T.; Cheng T.-J.R.; Juang Y.-P.; Ma H.-H.; Wu Y.-T.; Yang W.-B.; Cheng C.-W.; Chen X.; Chou T.-H.; Shie J.-J.; Cheng W.-C.; Chein R.-J.; Mao S.-S.; Liang P.-H.; Ma C.; Hung S.-C.; Wong C.-H.
收藏 | 浏览/下载：31/0 | 提交时间：2021/05/24 |
| Bepridil is potent against SARS-CoV-2 in vitro 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 10
作者: Vatansever E.C.; Yang K.S.; Drelich A.K.; Kratch K.C.; Cho C.-C.; Kempaiah K.R.; Hsu J.C.; Mellott D.M.; Xu S.; Tseng C.-T.K.; Liu W.R.
收藏 | 浏览/下载：28/0 | 提交时间：2021/05/24 |
| Combination prevention for COVID-19 期刊论文
Science, 2020, 卷号: 368, 期号: 6491
作者: Cohen M.S.; Corey L.
收藏 | 浏览/下载：1/0 | 提交时间：2022/01/14 |
| Underpromise, overdeliver 期刊论文
Science, 2020, 卷号: 367, 期号: 6485
作者: Thorp H.H.
收藏 | 浏览/下载：1/0 | 提交时间：2022/01/14 |
| Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者: Dai W.; Zhang B.; Jiang X.-M.; Su H.; Li J.; Zhao Y.; Xie X.; Jin Z.; Peng J.; Liu F.; Li C.; Li Y.; Bai F.; Wang H.; Cheng X.; Cen X.; Hu S.; Yang X.; Wang J.; Liu X.; Xiao G.; Jiang H.; Rao Z.; Zhang L.-K.; Xu Y.; Yang H.; Liu H.
收藏 | 浏览/下载：36/0 | 提交时间：2020/07/28
aldehyde antimicrobial activity drug enzyme activity infectivity inhibitor reaction kinetics viral disease Coronavirus SARS coronavirus 3C-like proteinase, Coronavirus antivirus agent cysteine proteinase viral protein animal Betacoronavirus chemical structure chemistry Chlorocebus aethiops Coronavirus infection dog drug design drug effect enzyme active site enzymology female human male mouse pandemic preclinical study protein tertiary structure Sprague Dawley rat toxicity testing Vero cell line virus pneumonia Animals Antiviral Agents Betacoronavirus Catalytic Domain Chlorocebus aethiops Coronavirus Infections Cysteine Endopeptidases Dogs Drug Design Drug Evaluation, Preclinical Female Humans Male Mice Molecular Structure Pandemics Pneumonia, Viral Protein Structure, Tertiary Rats, Sprague-Dawley Toxicity Tests Vero Cells Viral Nonstructural Proteins |
