中文版 | English

在结果中检索

CCPortal

浏览/检索结果: 共5条，第1-5条 帮助

已选(0)清除 条数/页：   排序方式：
Coronavirus replication-transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 6
作者:  Slanina H.;  Madhugiri R.;  Bylapudi G.;  Schultheiß K.;  Karl N.;  Gulyaeva A.;  Gorbalenya A.E.;  Linne U.;  Ziebuhr J.
收藏  |  浏览/下载：76/0  |  提交时间：2021/05/24
Generation of sars-cov-2 reporter replicon for high-throughput antiviral screening and testing 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 15
作者:  He X.;  Quan S.;  Xu M.;  Rodriguez S.;  Goh S.L.;  Wei J.;  Fridman A.;  Koeplinger K.A.;  Carroll S.S.;  Grobler J.A.;  Espeseth A.S.;  Olsen D.B.;  Hazuda D.J.;  Wang D.
收藏  |  浏览/下载：27/0  |  提交时间：2021/05/24
Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 7
作者:  Naydenova K.;  Muir K.W.;  Wu L.-F.;  Zhang Z.;  Coscia F.;  Peet M.J.;  Castro-Hartmann P.;  Qian P.;  Sader K.;  Dent K.;  Kimanius D.;  Sutherland J.D.;  Löwe J.;  Barford D.;  Russo C.J.
收藏  |  浏览/下载：29/0  |  提交时间：2021/05/24
Structure of the RNA-dependent RNA polymerase from COVID-19 virus 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Gao Y.;  Yan L.;  Huang Y.;  Liu F.;  Zhao Y.;  Cao L.;  Wang T.;  Sun Q.;  Ming Z.;  Zhang L.;  Ge J.;  Zheng L.;  Zhang Y.;  Wang H.;  Zhu Y.;  Zhu C.;  Hu T.;  Hua T.;  Zhang B.;  Yang X.;  Li J.;  Yang H.;  Liu Z.;  Xu W.;  Guddat L.W.;  Wang Q.;  Lou Z.;  Rao Z.
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/28
comparative study  drug  electron microscopy  enzyme  enzyme activity  RNA  virus  Coronavirus  SARS coronavirus  adenosine phosphate  alanine  antivirus agent  NSP7 protein, SARS-CoV-2  NSP8 protein, SARS-CoV-2  remdesivir  RNA directed RNA polymerase  RNA-dependent RNA polymerase, coronavirus  viral protein  beta sheet  Betacoronavirus  chemistry  cryoelectron microscopy  drug design  enzyme active site  enzymology  metabolism  molecular model  protein domain  ultrastructure  Adenosine Monophosphate  Alanine  Antiviral Agents  Betacoronavirus  Catalytic Domain  Cryoelectron Microscopy  Drug Design  Models, Molecular  Protein Conformation, beta-Strand  Protein Domains  RNA Replicase  Viral Nonstructural Proteins  
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文
, 2020, 卷号: 368, 期号: 6498
作者:  Yin W.;  Mao C.;  Luan X.;  Shen D.-D.;  Shen Q.;  Su H.;  Wang X.;  Zhou F.;  Zhao W.;  Gao M.;  Chang S.;  Xie Y.-C.;  Tian G.;  Jiang H.-W.;  Tao S.-C.;  Shen J.;  Jiang Y.;  Jiang H.;  Xu Y.;  Zhang S.;  Zhang Y.;  Xu H.E.
收藏  |  浏览/下载：89/0  |  提交时间：2020/07/28
adenosine phosphate  alanine  antivirus agent  enzyme inhibitor  multiprotein complex  NSP7 protein, SARS-CoV-2  NSP8 protein, SARS-CoV-2  remdesivir  RNA directed RNA polymerase  RNA-dependent RNA polymerase, coronavirus  viral protein  virus RNA  Betacoronavirus  chemistry  cryoelectron microscopy  drug effect  enzyme active site  enzymology  metabolism  molecular model  physiology  protein conformation  virus replication  Adenosine Monophosphate  Alanine  Antiviral Agents  Betacoronavirus  Catalytic Domain  Cryoelectron Microscopy  Enzyme Inhibitors  Models, Molecular  Multiprotein Complexes  Protein Conformation  RNA Replicase  RNA, Viral  Viral Nonstructural Proteins  Virus Replication