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Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat 期刊论文
, 2020, 卷号: 368, 期号: 6493
作者:  Wang H.;  Sun S.;  Ge W.;  Zhao L.;  Hou B.;  Wang K.;  Lyu Z.;  Chen L.;  Xu S.;  Guo J.;  Li M.;  Su P.;  Li X.;  Wang G.;  Bo C.;  Fang X.;  Zhuang W.;  Cheng X.;  Wu J.;  Dong L.;  Chen W.;  Li W.;  Xiao G.;  Zhao J.;  Hao Y.;  Xu Y.;  Gao Y.;  Liu W.;  Liu Y.;  Yin H.;  Li J.;  Li X.;  Zhao Y.;  Wang X.;  Ni F.;  Ma X.;  Li A.;  Xu S.S.;  Bai G.;  Nevo E.;  Gao C.;  Ohm H.;  Kong L.
收藏  |  浏览/下载:47/0  |  提交时间:2020/07/28
fungus  gene transfer  genome  germplasm  toxin  wheat  Fungi  Fusarium  Lophopyrum elongatum  Triticum aestivum  glutathione transferase  disease resistance  Epichloe  Fusarium  genetics  horizontal gene transfer  microbiology  molecular cloning  pathogenicity  plant breeding  plant disease  Poaceae  wheat  Cloning, Molecular  Disease Resistance  Epichloe  Fusarium  Gene Transfer, Horizontal  Glutathione Transferase  Plant Breeding  Plant Diseases  Poaceae  Triticum  
A general method to synthesize and sinter bulk ceramics in seconds 期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:  Wang C.;  Ping W.;  Bai Q.;  Cui H.;  Hensleigh R.;  Wang R.;  Brozena A.H.;  Xu Z.;  Dai J.;  Pei Y.;  Zheng C.;  Pastel G.;  Gao J.;  Wang X.;  Wang H.;  Zhao J.-C.;  Yang B.;  Zheng X.;  Luo J.;  Mo Y.;  Dunn B.;  Hu L.
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/28
electrolyte  ceramics  chemical composition  computer system  electrolyte  heating  mechanical property  radiative transfer  sinter  volatile element  Article  ceramics  chemical structure  high temperature procedures  high throughput screening  materials testing  priority journal  radiation  solid state  synthesis  ultrafast high temperature sintering  
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Dai W.;  Zhang B.;  Jiang X.-M.;  Su H.;  Li J.;  Zhao Y.;  Xie X.;  Jin Z.;  Peng J.;  Liu F.;  Li C.;  Li Y.;  Bai F.;  Wang H.;  Cheng X.;  Cen X.;  Hu S.;  Yang X.;  Wang J.;  Liu X.;  Xiao G.;  Jiang H.;  Rao Z.;  Zhang L.-K.;  Xu Y.;  Yang H.;  Liu H.
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28
aldehyde  antimicrobial activity  drug  enzyme activity  infectivity  inhibitor  reaction kinetics  viral disease  Coronavirus  SARS coronavirus  3C-like proteinase, Coronavirus  antivirus agent  cysteine proteinase  viral protein  animal  Betacoronavirus  chemical structure  chemistry  Chlorocebus aethiops  Coronavirus infection  dog  drug design  drug effect  enzyme active site  enzymology  female  human  male  mouse  pandemic  preclinical study  protein tertiary structure  Sprague Dawley rat  toxicity testing  Vero cell line  virus pneumonia  Animals  Antiviral Agents  Betacoronavirus  Catalytic Domain  Chlorocebus aethiops  Coronavirus Infections  Cysteine Endopeptidases  Dogs  Drug Design  Drug Evaluation, Preclinical  Female  Humans  Male  Mice  Molecular Structure  Pandemics  Pneumonia, Viral  Protein Structure, Tertiary  Rats, Sprague-Dawley  Toxicity Tests  Vero Cells  Viral Nonstructural Proteins  
Structure of the RNA-dependent RNA polymerase from COVID-19 virus 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Gao Y.;  Yan L.;  Huang Y.;  Liu F.;  Zhao Y.;  Cao L.;  Wang T.;  Sun Q.;  Ming Z.;  Zhang L.;  Ge J.;  Zheng L.;  Zhang Y.;  Wang H.;  Zhu Y.;  Zhu C.;  Hu T.;  Hua T.;  Zhang B.;  Yang X.;  Li J.;  Yang H.;  Liu Z.;  Xu W.;  Guddat L.W.;  Wang Q.;  Lou Z.;  Rao Z.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
comparative study  drug  electron microscopy  enzyme  enzyme activity  RNA  virus  Coronavirus  SARS coronavirus  adenosine phosphate  alanine  antivirus agent  NSP7 protein, SARS-CoV-2  NSP8 protein, SARS-CoV-2  remdesivir  RNA directed RNA polymerase  RNA-dependent RNA polymerase, coronavirus  viral protein  beta sheet  Betacoronavirus  chemistry  cryoelectron microscopy  drug design  enzyme active site  enzymology  metabolism  molecular model  protein domain  ultrastructure  Adenosine Monophosphate  Alanine  Antiviral Agents  Betacoronavirus  Catalytic Domain  Cryoelectron Microscopy  Drug Design  Models, Molecular  Protein Conformation, beta-Strand  Protein Domains  RNA Replicase  Viral Nonstructural Proteins  
Quantum interference in H + HD → H2 + D between direct abstraction and roaming insertion pathways 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Xie Y.;  Zhao H.;  Wang Y.;  Huang Y.;  Wang T.;  Xu X.;  Xiao C.;  Sun Z.;  Zhang D.H.;  Yang X.
收藏  |  浏览/下载:17/0  |  提交时间:2020/07/28
chemical reaction  energetics  oscillation  probe  quantum mechanics  topology  vibration  article  oscillation  physics  
N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者:  Liu J.;  Dou X.;  Chen C.;  Chen C.;  Liu C.;  Michelle Xu M.;  Zhao S.;  Shen B.;  Gao Y.;  Han D.;  He C.
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/28
6 n methyladenosine  chromosome associated regulatory RNA  enhancer RNA  messenger RNA  promoter associated RNA  repeat RNA  RNA  unclassified drug  cell component  chemical compound  chromosome  methylation  RNA  animal cell  Article  biodegradation  chemical modification  chromatin  controlled study  demethylation  embryo  embryonic stem cell  exosome  methylation  METTL3 gene  mouse  nonhuman  nuclear degradation  priority journal  transcription regulation  Ythdc1 gene  
An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Tian H.;  Liu Y.;  Li Y.;  Wu C.-H.;  Chen B.;  Kraemer M.U.G.;  Li B.;  Cai J.;  Xu B.;  Yang Q.;  Wang B.;  Yang P.;  Cui Y.;  Song Y.;  Zheng P.;  Wang Q.;  Bjornstad O.N.;  Yang R.;  Grenfell B.T.;  Pybus O.G.;  Dye C.
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/28
data set  disease control  disease incidence  disease transmission  epidemic  public health  viral disease  Article  China  coronavirus disease 2019  disease duration  disease transmission  epidemic  health care planning  human  incidence  infection control  influenza A (H1N1)  pandemic  patient isolation  priority journal  public health  sample size  scale up  traffic and transport  Betacoronavirus  communicable disease control  Coronavirus infection  epidemic  pandemic  public health service  regression analysis  statistical model  travel  virus pneumonia  China  Hubei  Wuhan  Coronavirus  Betacoronavirus  China  Communicable Disease Control  Coronavirus Infections  Epidemics  Humans  Incidence  Models, Statistical  Pandemics  Pneumonia, Viral  Public Health Practice  Regression Analysis  Travel  
Type-II Ising pairing in few-layer stanene 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:  Falson J.;  Xu Y.;  Liao M.;  Zang Y.;  Zhu K.;  Wang C.;  Zhang Z.;  Liu H.;  Duan W.;  He K.;  Liu H.;  Smet J.H.;  Zhang D.;  Xue Q.-K.
收藏  |  浏览/下载:84/0  |  提交时间:2020/07/28
stanene  tantalum  tantalum disulfide  tungsten derivative  tungsten disulfide  unclassified drug  low temperature  superconductivity  temperature effect  topology  two-dimensional modeling  angle resolved photoemission spectroscopy  anisotropy  Article  calculation  controlled study  cooling  low temperature  magnetic field  physical parameters  prediction  priority journal  qualitative analysis  temperature measurement  theoretical model  
CRISPR-engineered T cells in patients with refractory cancer 期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:  Stadtmauer E.A.;  Fraietta J.A.;  Davis M.M.;  Cohen A.D.;  Weber K.L.;  Lancaster E.;  Mangan P.A.;  Kulikovskaya I.;  Gupta M.;  Chen F.;  Tian L.;  Gonzalez V.E.;  Xu J.;  Jung I.-Y.;  Joseph Melenhorst J.;  Plesa G.;  Shea J.;  Matlawski T.;  Cervini A.;  Gaymon A.L.;  Desjardins S.;  Lamontagne A.;  Salas-Mckee J.;  Fesnak A.;  Siegel D.L.;  Levine B.L.;  Jadlowsky J.K.;  Young R.M.;  Chew A.;  Hwang W.-T.;  Hexner E.O.;  Carreno B.M.;  Nobles C.L.;  Bushman F.D.;  Parker K.R.;  Qi Y.;  Satpathy A.T.;  Chang H.Y.;  Zhao Y.;  Lacey S.F.;  June C.H.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
heterodimer  programmed death 1 receptor  T lymphocyte receptor alpha chain  T lymphocyte receptor beta chain  cancer  cell  gene  gene expression  genetic engineering  immunity  protein  adult  aged  Article  cancer patient  cell engineering  chromosome translocation  clinical article  clustered regularly interspaced short palindromic repeat  controlled study  CRISPR-CAS9 system  feasibility study  female  gene editing  gene expression  gene frequency  gene locus  genetic code  human  human cell  male  middle aged  myeloma  PDCD1 gene  phase 1 clinical trial  priority journal  sarcoma  T lymphocyte  TRAC gene  TRBC gene  tumor immunity  
Structure of nucleosome-bound human BAF complex 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  He S.;  Wu Z.;  Tian Y.;  Yu Z.;  Yu J.;  Wang X.;  Li J.;  Liu B.;  Xu Y.
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/28
actin related protein  adenosine triphosphatase  BRG1 BRM associated factor  DNA  multiprotein complex  protein SWI  retinoblastoma binding protein 2  SMARCC protein  SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily B member 1  transcription factor  transcription factor SNF  unclassified drug  cancer  enzyme activity  gene expression  hydrolysis  mutation  protein  alpha helix  Article  carboxy terminal sequence  cell interaction  cryoelectron microscopy  disease association  human  malignant neoplasm  molecular recognition  mutation  nucleosome  priority journal  protein function  protein hydrolysis  protein structure  structure analysis  Mammalia