气候变化领域集成服务门户(CCPortal): Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat

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DOI	10.1126/science.aba5435
	Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat
	Wang H.; Sun S.; Ge W.; Zhao L.; Hou B.; Wang K.; Lyu Z.; Chen L.; Xu S.; Guo J.; Li M.; Su P.; Li X.; Wang G.; Bo C.; Fang X.; Zhuang W.; Cheng X.; Wu J.; Dong L.; Chen W.; Li W.; Xiao G.; Zhao J.; Hao Y.; Xu Y.; Gao Y.; Liu W.; Liu Y.; Yin H.; Li J.; Li X.; Zhao Y.; Wang X.; Ni F.; Ma X.; Li A.; Xu S.S.; Bai G.; Nevo E.; Gao C.; Ohm H.; Kong L.
发表日期	2020
ISSN	0036-8075
卷号	368 期号:6493
英文摘要	Fusarium head blight (FHB), a fungal disease caused by Fusarium species that produce food toxins, currently devastates wheat production worldwide, yet few resistance resources have been discovered in wheat germplasm. Here, we cloned the FHB resistance gene Fhb7 by assembling the genome of Thinopyrum elongatum, a species used in wheat distant hybridization breeding. Fhb7 encodes a glutathione S-transferase (GST) and confers broad resistance to Fusarium species by detoxifying trichothecenes through de-epoxidation. Fhb7 GST homologs are absent in plants, and our evidence supports that Th. elongatum has gained Fhb7 through horizontal gene transfer (HGT) from an endophytic Epichloë species. Fhb7 introgressions in wheat confers resistance to both FHB and crown rot in diverse wheat backgrounds without yield penalty, providing a solution for Fusarium resistance breeding. © 2020 American Association for the Advancement of Science. All rights reserved.
关键词	fungus gene transfer genome germplasm toxin wheat Fungi Fusarium Lophopyrum elongatum Triticum aestivum glutathione transferase disease resistance Epichloe Fusarium genetics horizontal gene transfer microbiology molecular cloning pathogenicity plant breeding plant disease Poaceae wheat Cloning, Molecular Disease Resistance Epichloe Fusarium Gene Transfer, Horizontal Glutathione Transferase Plant Breeding Plant Diseases Poaceae Triticum
语种	英语
来源机构	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/133490
推荐引用方式 GB/T 7714	Wang H.,Sun S.,Ge W.,et al. Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat[J]. Science,2020,368(6493).
APA	Wang H..,Sun S..,Ge W..,Zhao L..,Hou B..,...&Kong L..(2020).Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat.,368(6493).
MLA	Wang H.,et al."Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat".368.6493(2020).