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期刊论文 [22]
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2020 [22]
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Science [22]
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Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:
Dai W.
;
Zhang B.
;
Jiang X.-M.
;
Su H.
;
Li J.
;
Zhao Y.
;
Xie X.
;
Jin Z.
;
Peng J.
;
Liu F.
;
Li C.
;
Li Y.
;
Bai F.
;
Wang H.
;
Cheng X.
;
Cen X.
;
Hu S.
;
Yang X.
;
Wang J.
;
Liu X.
;
Xiao G.
;
Jiang H.
;
Rao Z.
;
Zhang L.-K.
;
Xu Y.
;
Yang H.
;
Liu H.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
aldehyde
antimicrobial activity
drug
enzyme activity
infectivity
inhibitor
reaction kinetics
viral disease
Coronavirus
SARS coronavirus
3C-like proteinase, Coronavirus
antivirus agent
cysteine proteinase
viral protein
animal
Betacoronavirus
chemical structure
chemistry
Chlorocebus aethiops
Coronavirus infection
dog
drug design
drug effect
enzyme active site
enzymology
female
human
male
mouse
pandemic
preclinical study
protein tertiary structure
Sprague Dawley rat
toxicity testing
Vero cell line
virus pneumonia
Animals
Antiviral Agents
Betacoronavirus
Catalytic Domain
Chlorocebus aethiops
Coronavirus Infections
Cysteine Endopeptidases
Dogs
Drug Design
Drug Evaluation, Preclinical
Female
Humans
Male
Mice
Molecular Structure
Pandemics
Pneumonia, Viral
Protein Structure, Tertiary
Rats, Sprague-Dawley
Toxicity Tests
Vero Cells
Viral Nonstructural Proteins
Effective containment explains subexponential growth in recent confirmed COVID-19 cases in China
期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:
Maier B.F.
;
Brockmann D.
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/28
disease control
disease prevalence
epidemic
health geography
public health
quarantine
symptom
viral disease
China
Coronavirus
basic reproduction number
behavior
Betacoronavirus
China
communicable disease control
contact examination
Coronavirus infection
disease predisposition
epidemic
human
pandemic
quarantine
statistical model
virus pneumonia
Basic Reproduction Number
Behavior
Betacoronavirus
China
Communicable Disease Control
Contact Tracing
Coronavirus Infections
Disease Outbreaks
Disease Susceptibility
Humans
Models, Statistical
Pandemics
Pneumonia, Viral
Quarantine
Moving academic research forward during COVID-19
期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:
Wigginton N.S.
;
Cunningham R.M.
;
Katz R.H.
;
Lidstrom M.E.
;
Moler K.A.
;
Wirtz D.
;
Zuber M.T.
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/28
academic research
decision making
higher education
learning
public health
student
teaching
university sector
viral disease
virus
Coronavirus infection
health care policy
human
organization
pandemic
United States
virus pneumonia
Academies and Institutes
Coronavirus Infections
Health Policy
Humans
Pandemics
Pneumonia, Viral
United States
Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Ferretti L.
;
Wymant C.
;
Kendall M.
;
Zhao L.
;
Nurtay A.
;
Abeler-Dörner L.
;
Parker M.
;
Bonsall D.
;
Fraser C.
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/28
disease control
epidemic
memory
parasite transmission
viral disease
Article
asymptomatic disease
China
contact examination
coronavirus disease 2019
disease control
disease transmission
health care system
human
incubation time
mathematical model
mobile application
mortality rate
priority journal
quarantine
rating scale
Severe acute respiratory syndrome coronavirus 2
virus transmission
algorithm
basic reproduction number
Betacoronavirus
contact examination
Coronavirus infection
epidemic
ethics
infection control
mobile application
mobile phone
pandemic
probability
procedures
theoretical model
time factor
virus pneumonia
Coronavirus
SARS coronavirus
Algorithms
Asymptomatic Diseases
Basic Reproduction Number
Betacoronavirus
Cell Phone
China
Contact Tracing
Coronavirus Infections
Epidemics
Humans
Infection Control
Mobile Applications
Models, Theoretical
Pandemics
Pneumonia, Viral
Probability
Quarantine
Time Factors
Rapid implementation of mobile technology for real-time epidemiology of COVID-19
期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:
Drew D.A.
;
Nguyen L.H.
;
Steves C.J.
;
Menni C.
;
Freydin M.
;
Varsavsky T.
;
Sudre C.H.
;
Jorge Cardoso M.
;
Ourselin S.
;
Wolf J.
;
Spector T.D.
;
Chan A.T.
;
COPE Consortium
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/28
data assimilation
epidemiology
public health
real time
risk factor
severe acute respiratory syndrome
viral disease
United Kingdom
United States
Coronavirus
SARS coronavirus
Betacoronavirus
Coronavirus infection
devices
global health
human
information processing
international cooperation
mobile application
pandemic
procedures
theoretical model
United Kingdom
United States
virus pneumonia
Betacoronavirus
Big Data
Coronavirus Infections
Data Collection
Global Health
Humans
International Cooperation
Mobile Applications
Models, Theoretical
Pandemics
Pneumonia, Viral
United Kingdom
United States
Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model
期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:
Rockx B.
;
Kuiken T.
;
Herfst S.
;
Bestebroer T.
;
Lamers M.M.
;
Munnink B.B.O.
;
De Meulder D.
;
Van Amerongen G.
;
Van Den Brand J.
;
Okba N.M.A.
;
Schipper D.
;
Van Run P.
;
Leijten L.
;
Sikkema R.
;
Verschoor E.
;
Verstrepen B.
;
Bogers W.
;
Langermans J.
;
Langermans J.
;
Drosten C.
;
Van Vlissingen M.F.
;
Fouchier R.
;
De Swart R.
;
Koopmans M.
;
Haagmans B.L.
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/28
pathogenicity
pathology
primate
severe acute respiratory syndrome
viral disease
virus
Middle East
Coronavirus
Macaca
Primates
SARS coronavirus
aging
animal
Betacoronavirus
comparative study
Coronavirus infection
disease model
female
isolation and purification
lung
lung alveolus
Macaca fascicularis
Middle East respiratory syndrome coronavirus
pandemic
pathogenicity
pathology
physiology
respiratory system
SARS coronavirus
severe acute respiratory syndrome
virology
virus pneumonia
virus replication
virus shedding
Aging
Animals
Betacoronavirus
Coronavirus Infections
Disease Models, Animal
Female
Lung
Macaca fascicularis
Middle East Respiratory Syndrome Coronavirus
Pandemics
Pneumonia, Viral
Pulmonary Alveoli
Respiratory System
SARS Virus
Severe Acute Respiratory Syndrome
Virus Replication
Virus Shedding
Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2
期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:
Shi J.
;
Wen Z.
;
Zhong G.
;
Yang H.
;
Wang C.
;
Huang B.
;
Liu R.
;
He X.
;
Shuai L.
;
Sun Z.
;
Zhao Y.
;
Liu P.
;
Liang L.
;
Cui P.
;
Wang J.
;
Zhang X.
;
Guan Y.
;
Tan W.
;
Wu G.
;
Chen H.
;
Bu Z.
;
Bu Z.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
bat
canid
disease control
disease transmission
felid
global perspective
infectious disease
poultry
severe acute respiratory syndrome
viral disease
virus
China
Hubei
Wuhan
Anas
Animalia
Canis familiaris
Coronavirus
Gallus gallus
Mustela
SARS coronavirus
Suidae
virus antibody
virus RNA
animal
Betacoronavirus
blood
cat
chicken
Coronavirus infection
disease model
disease predisposition
dog
domestic animal
duck
feces
female
immunology
isolation and purification
male
Mustela putorius furo
pandemic
physiology
pig
respiratory system
species difference
virology
virus attachment
virus pneumonia
virus replication
Animals
Animals, Domestic
Antibodies, Viral
Betacoronavirus
Cats
Chickens
Coronavirus Infections
Disease Models, Animal
Disease Susceptibility
Dogs
Ducks
Feces
Female
Ferrets
Male
Pandemics
Pneumonia, Viral
Respiratory System
RNA, Viral
Species Specificity
Sus scrofa
Virus Attachment
Virus Replication
Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period
期刊论文
, 2020, 卷号: 368, 期号: 6493
作者:
Kissler S.M.
;
Tedijanto C.
;
Goldstein E.
;
Grad Y.H.
;
Lipsitch M.
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/28
data set
disease transmission
immunity
virus
United States
Coronavirus
SARS coronavirus
Betacoronavirus
biological model
Coronavirus infection
disease transmission
epidemic
human
Human coronavirus OC43
immunology
pandemic
physiology
season
virology
virus pneumonia
Betacoronavirus
Coronavirus Infections
Coronavirus OC43, Human
Disease Outbreaks
Disease Transmission, Infectious
Humans
Models, Biological
Pandemics
Pneumonia, Viral
Seasons
An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Tian H.
;
Liu Y.
;
Li Y.
;
Wu C.-H.
;
Chen B.
;
Kraemer M.U.G.
;
Li B.
;
Cai J.
;
Xu B.
;
Yang Q.
;
Wang B.
;
Yang P.
;
Cui Y.
;
Song Y.
;
Zheng P.
;
Wang Q.
;
Bjornstad O.N.
;
Yang R.
;
Grenfell B.T.
;
Pybus O.G.
;
Dye C.
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/28
data set
disease control
disease incidence
disease transmission
epidemic
public health
viral disease
Article
China
coronavirus disease 2019
disease duration
disease transmission
epidemic
health care planning
human
incidence
infection control
influenza A (H1N1)
pandemic
patient isolation
priority journal
public health
sample size
scale up
traffic and transport
Betacoronavirus
communicable disease control
Coronavirus infection
epidemic
pandemic
public health service
regression analysis
statistical model
travel
virus pneumonia
China
Hubei
Wuhan
Coronavirus
Betacoronavirus
China
Communicable Disease Control
Coronavirus Infections
Epidemics
Humans
Incidence
Models, Statistical
Pandemics
Pneumonia, Viral
Public Health Practice
Regression Analysis
Travel
A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:
Wu Y.
;
Wang F.
;
Shen C.
;
Peng W.
;
Li D.
;
Zhao C.
;
Li Z.
;
Li S.
;
Bi Y.
;
Yang Y.
;
Gong Y.
;
Xiao H.
;
Fan Z.
;
Tan S.
;
Wu G.
;
Tan W.
;
Lu X.
;
Fan C.
;
Wang Q.
;
Liu Y.
;
Zhang C.
;
Qi J.
;
Gao G.F.
;
Gao F.
;
Liu L.
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/28
Coronavirus
angiotensin converting enzyme 2
coronavirus spike glycoprotein
dipeptidyl carboxypeptidase
epitope
monoclonal antibody
neutralizing antibody
virus antibody
virus receptor
animal
chemistry
Coronavirus infection
disease model
human
immunology
isolation and purification
lung
mouse
pandemic
protein domain
serodiagnosis
virology
virus load
virus pneumonia
Animals
Antibodies, Monoclonal
Antibodies, Neutralizing
Antibodies, Viral
Coronavirus Infections
Disease Models, Animal
Humans
Immunodominant Epitopes
Lung
Mice
Neutralization Tests
Pandemics
Peptidyl-Dipeptidase A
Pneumonia, Viral
Protein Domains
Receptors, Virus
Spike Glycoprotein, Coronavirus
Viral Load