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Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations
期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:
Wilmes S.
;
Hafer M.
;
Vuorio J.
;
Tucker J.A.
;
Winkelmann H.
;
Löchte S.
;
Stanly T.A.
;
Pulgar Prieto K.D.
;
Poojari C.
;
Sharma V.
;
Richter C.P.
;
Kurre R.
;
Hubbard S.R.
;
Christopher Garcia K.
;
Moraga I.
;
Vattulainen I.
;
Hitchcock I.S.
;
Piehler J.
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/28
cytokine receptor
homodimer
Janus kinase 2
ligand
oncoprotein
cancer
enzyme
enzyme activity
membrane
molecular analysis
mutation
protein
activation analysis
Article
cell membrane
computer model
controlled study
dimerization
fluorescence microscopy
gene mutation
HeLa cell line
molecular dynamics
mutant
oncogene
priority journal
protein domain
protein interaction
quantitative analysis
signal transduction
Membrane-proximal F-actin restricts local membrane protrusions and directs cell migration
期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:
Bisaria A.
;
Hayer A.
;
Garbett D.
;
Cohen D.
;
Meyer T.
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/28
cell component
concentration (composition)
membrane
polymerization
protein
actin
green fluorescent protein
cell membrane
cell motion
cell polarity
cell surface
chemistry
genetics
human
metabolism
umbilical vein endothelial cell
Actins
Cell Membrane
Cell Movement
Cell Polarity
Cell Surface Extensions
Green Fluorescent Proteins
Human Umbilical Vein Endothelial Cells
Humans
Microenvironment mapping via Dexter energy transfer on immune cells
期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:
Geri J.B.
;
Oakley J.V.
;
Reyes-Robles T.
;
Wang T.
;
McCarver S.J.
;
White C.H.
;
Rodriguez-Rivera F.P.
;
Parker D.L.
;
Hett E.C.
;
Fadeyi O.O.
;
Oslund R.C.
;
MacMillan D.W.C.
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/28
antibody conjugate
carbene
programmed death 1 ligand 1
methane
programmed death 1 ligand 1
antibody
catalysis
catalyst
cell component
detection method
enzyme
enzyme activity
protein
antigen binding
Article
cell membrane
energy transfer
human
immunocompetent cell
immunological synapse
lymphocyte
photocatalysis
priority journal
protein analysis
protein protein interaction
tumor microenvironment
catalysis
chemistry
energy transfer
Jurkat cell line
metabolism
photochemistry
procedures
radiation response
ultraviolet radiation
B7-H1 Antigen
Catalysis
Cell Membrane
Cellular Microenvironment
Energy Transfer
Humans
Jurkat Cells
Lymphocytes
Methane
Photochemical Processes
Protein Interaction Mapping
Protein Interaction Maps
Ultraviolet Rays
PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis
期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:
Wang Q.
;
Boshoff H.I.M.
;
Harrison J.R.
;
Ray P.C.
;
Green S.R.
;
Wyatt P.G.
;
Barry Iii C.E.
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/28
3,3 bis di(methylsulfonyl)propionamide
antiinfective agent
bacterial protein
glucose
glycerol
magnesium
phosphate
propionamide derivative
protein proline proline glutamate
protein proline proline glutamate 51
unclassified drug
amide
bacterial protein
lipid
phthiocerol dimycocerosate
propionamide
thiol derivative
cell component
chemical compound
membrane
mutation
protein
tuberculosis
antibiotic resistance
Article
bacterial cell
bacterial cell wall
bacterial growth
bacterial outer membrane
cell division
drug structure
Mycobacterium tuberculosis
nonhuman
nutrient uptake
priority journal
protein depletion
cell membrane
cell membrane permeability
chemistry
drug effect
gene deletion
genetics
metabolism
transport at the cellular level
Mycobacterium tuberculosis
Amides
Bacterial Proteins
Biological Transport
Cell Membrane
Cell Membrane Permeability
Drug Resistance, Bacterial
Gene Deletion
Glucose
Glycerol
Lipids
Mycobacterium tuberculosis
Sulfhydryl Compounds
Pectin homogalacturonan nanofilament expansion drives morphogenesis in plant epidermal cells
期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:
Haas K.T.
;
Wightman R.
;
Meyerowitz E.M.
;
Peaucelle A.
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/07/28
cellulose
glycan
hemicellulose
pectin
pectin homogalacturonan
polysaccharide
unclassified drug
biochemistry
body shape
cell
morphogenesis
physiological response
protein
shape analysis
anisotropy
Arabidopsis
Article
cell membrane
cell shape
cell wall
controlled study
cotyledon
demethylation
epidermis cell
extracellular matrix
fibril
morphogenesis
nanoimaging
nonhuman
plant cell
plant growth
priority journal
protein domain
turgor pressure
Animalia
Endoplasmic reticulum contact sites regulate the dynamics of membraneless organelles
期刊论文
, 2020, 卷号: 367, 期号: 6477
作者:
Lee J.E.
;
Cathey P.I.
;
Wu H.
;
Parker R.
;
Voeltz G.K.
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/28
cell component
cell organelle
membrane
protein
Article
biogenesis
cell division
cell organelle
cell population
cell proliferation
cell structure
controlled study
cytoplasm
dimerization
endoplasmic reticulum
endoplasmic reticulum stress
endosome
fluorescence microscopy
human
human cell
membraneless organelle
mitochondrion
priority journal
ribonucleoprotein granule
RNA translation
stress granule
HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease
期刊论文
, 2020, 卷号: 369, 期号: 6500
作者:
Cook S.A.
;
Comrie W.A.
;
Poli M.C.
;
Similuk M.
;
Oler A.J.
;
Faruqi A.J.
;
Kuhns D.B.
;
Yang S.
;
Vargas-Hernández A.
;
Carisey A.F.
;
Fournier B.
;
Anderson D.E.
;
Price S.
;
Smelkinson M.
;
Abou Chahla W.
;
Forbes L.R.
;
Mace E.M.
;
Cao T.N.
;
Coban-Akdemir Z.H.
;
Jhangiani S.N.
;
Muzny D.M.
;
Gibbs R.A.
;
Lupski J.R.
;
Orange J.S.
;
Cuvelier G.D.E.
;
Al Hassani M.
;
Al Kaabi N.
;
Al Yafei Z.
;
Jyonouchi S.
;
Raje N.
;
Caldwell J.W.
;
Huang Y.
;
Burkhardt J.K.
;
Latour S.
;
Chen B.
;
ElGhazali G.
;
Rao V.K.
;
Chinn I.K.
;
Lenardo M.J.
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/07/28
actin
adenosine diphosphate ribosylation factor 1
ARF1 protein, human
cytokine
mammalian target of rapamycin complex 2
membrane protein
NCKAP1L protein, human
WASF1 protein, human
WASF2 protein, human
WASF3 protein, human
Wiskott Aldrich syndrome protein
biosynthesis
CD4+ T lymphocyte
cell proliferation
chemistry
genetics
human
immune deficiency
immunology
lymphoproliferative disease
metabolism
pedigree
phosphorylation
physiology
Actins
ADP-Ribosylation Factor 1
CD4-Positive T-Lymphocytes
Cell Proliferation
Cytokines
Humans
Immunologic Deficiency Syndromes
Lymphoproliferative Disorders
Mechanistic Target of Rapamycin Complex 2
Membrane Proteins
Pedigree
Phosphorylation
Wiskott-Aldrich Syndrome Protein Family
Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division
期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:
Nagashima S.
;
Tábara L.-C.
;
Tilokani L.
;
Paupe V.
;
Anand H.
;
Pogson J.H.
;
Zunino R.
;
McBride H.M.
;
Prudent J.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
adenosine diphosphate ribosylation factor 1
dynamin related protein 1
mitochondrial protein
phosphatidylinositol 4 kinase IIIbeta
phosphatidylinositol 4 phosphate
phosphatidylinositol kinase
unclassified drug
adenosine diphosphate ribosylation factor 1
ARF1 protein, human
DNM1L protein, human
dynamin
phosphatidylinositol 4-phosphate
phosphatidylinositol kinase
polyphosphoinositide
cell component
cell organelle
chemical compound
enzyme
enzyme activity
mitochondrion
protein
Article
controlled study
COS-7 cell line
endoplasmic reticulum
fibroblast
gene silencing
HeLa cell line
human
human cell
membrane microdomain
mitochondrial division
mitochondrial dynamics
mitochondrial scission
priority journal
protein localization
trans Golgi network
U2OS cell line
animal
cell line
Chlorocebus aethiops
CV-1 cell line
genetics
metabolism
mitochondrial membrane
mitochondrion
RNA interference
trans Golgi network
ultrastructure
Mammalia
1-Phosphatidylinositol 4-Kinase
ADP-Ribosylation Factor 1
Animals
Cell Line
Chlorocebus aethiops
COS Cells
Dynamins
Endoplasmic Reticulum
HeLa Cells
Humans
Membrane Microdomains
Mitochondria
Mitochondrial Dynamics
Mitochondrial Membranes
Phosphatidylinositol Phosphates
RNA Interference
trans-Golgi Network
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance
期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:
ElTanbouly M.A.
;
Zhao Y.
;
Nowak E.
;
Li J.
;
Schaafsma E.
;
Le Mercier I.
;
Ceeraz S.
;
Lines J.L.
;
Peng C.
;
Carriere C.
;
Huang X.
;
Day M.
;
Koehn B.
;
Lee S.W.
;
Morales M.S.
;
Hogquist K.A.
;
Jameson S.C.
;
Mueller D.
;
Rothstein J.
;
Blazar B.R.
;
Cheng C.
;
Noelle R.J.
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2020/07/28
cell protein
interferon
kruppel like factor 2
T lymphocyte receptor
unclassified drug
V type immunoglobulin domain containing suppressor of T cell activation protein
B7 antigen
Dies1 protein, mouse
lymphocyte antigen receptor
membrane protein
monoclonal antibody
VSIR protein, human
biological development
cell
gene expression
heterogeneity
homeostasis
immune response
immunity
tolerance
acute graft versus host disease
animal cell
animal experiment
animal model
Article
CD4+ T lymphocyte
cell death
cell expansion
cell fate
cell heterogeneity
cell loss
cell survival
controlled study
female
gene
gene deletion
homeostasis
immunological tolerance
in vivo study
long term survival
male
mouse
nonhuman
phenotype
priority journal
protein expression
protein function
rheumatoid arthritis
RNA sequencing
systemic lupus erythematosus
T lymphocyte
T lymphocyte activation
T lymphocyte subpopulation
TCR gene
upregulation
VISTA gene
animal
C57BL mouse
genetics
immunological tolerance
immunology
knockout mouse
lymphocyte activation
physiology
T lymphocyte
Mus
Animals
Antibodies, Monoclonal
B7 Antigens
Lymphocyte Activation
Membrane Proteins
Mice
Mice, Inbred C57BL
Mice, Knockout
Peripheral Tolerance
Receptors, Antigen, T-Cell
T-Lymphocytes
Endoplasmic reticulum-associated degradation regulates mitochondrial dynamics in brown adipocytes
期刊论文
, 2020, 卷号: 368, 期号: 6486
作者:
Zhou Z.
;
Torres M.
;
Sha H.
;
Halbrook C.J.
;
van den Bergh F.
;
Reinert R.B.
;
Yamada T.
;
Wang S.
;
Luo Y.
;
Hunter A.H.
;
Wang C.
;
Sanderson T.H.
;
Liu M.
;
Taylor A.
;
Sesaki H.
;
Lyssiotis C.A.
;
Wu J.
;
Kersten S.
;
Beard D.A.
;
Qi L.
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/28
Hrd1 protein
membrane protein
Sel1L protein
sigma opiate receptor
sigma receptor 1
ubiquitin protein ligase E3
unclassified drug
biodegradation
cell organelle
membrane
mitochondrion
physiology
protein
turnover
animal cell
Article
brown adipocyte
cell contact
controlled study
endoplasmic reticulum
endoplasmic reticulum associated degradation
megamitochondria
mitochondrial dynamics
mitochondrion
mouse
nonhuman
priority journal
protein metabolism
protein protein interaction
thermogenesis
three-dimensional imaging
Mus