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4E-BP2-dependent translation in parvalbumin neurons controls epileptic seizure threshold 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 15
作者:  Sharma V.;  Sood R.;  Lou D.;  Hung T.-Y.;  Lévesque M.;  Han Y.;  Levett J.Y.;  Wang P.;  Murthy S.;  Tansley S.;  Wang S.;  Siddiqui N.;  Tahmasebi S.;  Rosenblum K.;  Avoli M.;  Lacaille J.-C.;  Sonenberg N.;  Khoutorsky A.
收藏  |  浏览/下载:28/0  |  提交时间:2021/05/24
Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 39
作者:  Wang J.;  Filippakis H.;  Hougard T.;  Du H.;  Ye C.;  Liu H.-J.;  Zhang L.;  Hindi K.;  Bagwe S.;  Nijmeh J.;  Asara J.M.;  Shi W.;  El-Chemaly S.;  Henske E.P.;  Lam H.C.
收藏  |  浏览/下载:92/0  |  提交时间:2021/11/25
Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 6
作者:  Mukhopadhyay S.;  Biancur D.E.;  Parker S.J.;  Yamamoto K.;  Banh R.S.;  Paulo J.A.;  Mancias J.D.;  Kimmelman A.C.
收藏  |  浏览/下载:27/0  |  提交时间:2021/05/24
Calcineurin regulates the stability and activity of estrogen receptor α 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 44
作者:  Masaki T.;  Habara M.;  Sato Y.;  Goshima T.;  Maeda K.;  Hanaki S.;  Shimada M.
收藏  |  浏览/下载:35/0  |  提交时间:2022/02/22
RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 33
作者:  Castel P.;  Dharmaiah S.;  Sale M.J.;  Messing S.;  Rizzuto G.;  Cuevas-Navarro A.;  Cheng A.;  Trnka M.J.;  Urisman A.;  Esposito D.;  Simanshu D.K.;  McCormick F.
收藏  |  浏览/下载:93/0  |  提交时间:2022/02/22
PIP4Ks impact on PI3K, FOXP3, and UHRF1 signaling and modulate human regulatory T cell proliferation and immunosuppressive activity 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 31
作者:  Poli A.;  Abdul-Hamid S.;  Zaurito A.E.;  Campagnoli F.;  Bevilacqua V.;  Sheth B.;  Fiume R.;  Pagani M.;  Abrignani S.;  Divecha N.
收藏  |  浏览/下载:25/0  |  提交时间:2022/02/22
SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic stress 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 33
作者:  Kobayashi T.;  Nguyen-Tien D.;  Sorimachi Y.;  Sugiura Y.;  Suzuki T.;  Karyu H.;  Shimabukuro-Demoto S.;  Uemura T.;  Okamura T.;  Taguchi T.;  Ueki K.;  Kato N.;  Goda N.;  Dohmae N.;  Takubo K.;  Suematsu M.;  Toyama-Sorimachi N.
收藏  |  浏览/下载:35/0  |  提交时间:2021/11/25
mTORC1-chaperonin CCT signaling regulates m6A RNA methylation to suppress autophagy 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 10
作者:  Tang H.-W.;  Weng J.-H.;  Lee W.X.;  Hu Y.;  Gu L.;  Cho S.;  Lee G.;  Binari R.;  Li C.;  Cheng M.E.;  Kim A.-R.;  Xu J.;  Shen Z.;  Xu C.;  Asara J.M.;  Blenis J.;  Perrimon N.
收藏  |  浏览/下载:39/0  |  提交时间:2021/05/24
HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease 期刊论文
, 2020, 卷号: 369, 期号: 6500
作者:  Cook S.A.;  Comrie W.A.;  Poli M.C.;  Similuk M.;  Oler A.J.;  Faruqi A.J.;  Kuhns D.B.;  Yang S.;  Vargas-Hernández A.;  Carisey A.F.;  Fournier B.;  Anderson D.E.;  Price S.;  Smelkinson M.;  Abou Chahla W.;  Forbes L.R.;  Mace E.M.;  Cao T.N.;  Coban-Akdemir Z.H.;  Jhangiani S.N.;  Muzny D.M.;  Gibbs R.A.;  Lupski J.R.;  Orange J.S.;  Cuvelier G.D.E.;  Al Hassani M.;  Al Kaabi N.;  Al Yafei Z.;  Jyonouchi S.;  Raje N.;  Caldwell J.W.;  Huang Y.;  Burkhardt J.K.;  Latour S.;  Chen B.;  ElGhazali G.;  Rao V.K.;  Chinn I.K.;  Lenardo M.J.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
actin  adenosine diphosphate ribosylation factor 1  ARF1 protein, human  cytokine  mammalian target of rapamycin complex 2  membrane protein  NCKAP1L protein, human  WASF1 protein, human  WASF2 protein, human  WASF3 protein, human  Wiskott Aldrich syndrome protein  biosynthesis  CD4+ T lymphocyte  cell proliferation  chemistry  genetics  human  immune deficiency  immunology  lymphoproliferative disease  metabolism  pedigree  phosphorylation  physiology  Actins  ADP-Ribosylation Factor 1  CD4-Positive T-Lymphocytes  Cell Proliferation  Cytokines  Humans  Immunologic Deficiency Syndromes  Lymphoproliferative Disorders  Mechanistic Target of Rapamycin Complex 2  Membrane Proteins  Pedigree  Phosphorylation  Wiskott-Aldrich Syndrome Protein Family  
Glucose-dependent control of leucine metabolism by leucyl-tRNA synthetase 1 期刊论文
, 2020, 卷号: 367, 期号: 6474
作者:  Yoon I.;  Nam M.;  Kim H.K.;  Moon H.-S.;  Kim S.;  Jang J.;  Song J.A.;  Jeong S.J.;  Kim S.B.;  Cho S.;  Kim Y.;  Lee J.;  Yang W.S.;  Yoo H.C.;  Kim K.;  Kim M.-S.;  Yang A.;  Cho K.;  Park H.-S.;  Hwang G.-S.;  Hwang K.Y.;  Han J.M.;  Kim J.H.;  Kim S.
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/28
glucose  leucine  leucine transfer RNA ligase  leucyl tRNA synthetase 1  mammalian target of rapamycin complex 1  S6 kinase  serine threonine protein kinase ULK1  unclassified drug  glucose  leucine  leucine transfer RNA ligase  mammalian target of rapamycin complex 1  monomeric guanine nucleotide binding protein  serine threonine protein kinase ULK1  catabolism  cell  enzyme  enzyme activity  glucose  metabolism  protein  survival  amino acid metabolism  animal cell  Article  binding affinity  cell survival  circular dichroism  controlled study  embryo  energy yield  enzyme activity  enzyme phosphorylation  enzyme regulation  fluorescence resonance energy transfer  human  human cell  mouse  nonhuman  priority journal  protein binding  protein domain  protein motif  protein processing  protein synthesis  signal transduction  starvation  animal  energy metabolism  fibroblast  genetics  HEK293 cell line  HeLa cell line  lysosome  metabolism  phosphorylation  Animals  Autophagy-Related Protein-1 Homolog  Energy Metabolism  Fibroblasts  Glucose  HEK293 Cells  HeLa Cells  Humans  Leucine  Leucine-tRNA Ligase  Lysosomes  Mechanistic Target of Rapamycin Complex 1  Mice  Monomeric GTP-Binding Proteins  Phosphorylation  Signal Transduction