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| 4E-BP2-dependent translation in parvalbumin neurons controls epileptic seizure threshold 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 15 作者: Sharma V.; Sood R.; Lou D.; Hung T.-Y.; Lévesque M.; Han Y.; Levett J.Y.; Wang P.; Murthy S.; Tansley S.; Wang S.; Siddiqui N.; Tahmasebi S.; Rosenblum K.; Avoli M.; Lacaille J.-C.; Sonenberg N.; Khoutorsky A. 收藏  |  浏览/下载:28/0  |  提交时间:2021/05/24 |
| Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 39 作者: Wang J.; Filippakis H.; Hougard T.; Du H.; Ye C.; Liu H.-J.; Zhang L.; Hindi K.; Bagwe S.; Nijmeh J.; Asara J.M.; Shi W.; El-Chemaly S.; Henske E.P.; Lam H.C. 收藏  |  浏览/下载:92/0  |  提交时间:2021/11/25 |
| Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 6 作者: Mukhopadhyay S.; Biancur D.E.; Parker S.J.; Yamamoto K.; Banh R.S.; Paulo J.A.; Mancias J.D.; Kimmelman A.C. 收藏  |  浏览/下载:27/0  |  提交时间:2021/05/24 |
| Calcineurin regulates the stability and activity of estrogen receptor α 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 44 作者: Masaki T.; Habara M.; Sato Y.; Goshima T.; Maeda K.; Hanaki S.; Shimada M. 收藏  |  浏览/下载:35/0  |  提交时间:2022/02/22 |
| RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 33 作者: Castel P.; Dharmaiah S.; Sale M.J.; Messing S.; Rizzuto G.; Cuevas-Navarro A.; Cheng A.; Trnka M.J.; Urisman A.; Esposito D.; Simanshu D.K.; McCormick F. 收藏  |  浏览/下载:93/0  |  提交时间:2022/02/22 |
| PIP4Ks impact on PI3K, FOXP3, and UHRF1 signaling and modulate human regulatory T cell proliferation and immunosuppressive activity 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 31 作者: Poli A.; Abdul-Hamid S.; Zaurito A.E.; Campagnoli F.; Bevilacqua V.; Sheth B.; Fiume R.; Pagani M.; Abrignani S.; Divecha N. 收藏  |  浏览/下载:25/0  |  提交时间:2022/02/22 |
| SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic stress 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 33 作者: Kobayashi T.; Nguyen-Tien D.; Sorimachi Y.; Sugiura Y.; Suzuki T.; Karyu H.; Shimabukuro-Demoto S.; Uemura T.; Okamura T.; Taguchi T.; Ueki K.; Kato N.; Goda N.; Dohmae N.; Takubo K.; Suematsu M.; Toyama-Sorimachi N. 收藏  |  浏览/下载:35/0  |  提交时间:2021/11/25 |
| mTORC1-chaperonin CCT signaling regulates m6A RNA methylation to suppress autophagy 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 10 作者: Tang H.-W.; Weng J.-H.; Lee W.X.; Hu Y.; Gu L.; Cho S.; Lee G.; Binari R.; Li C.; Cheng M.E.; Kim A.-R.; Xu J.; Shen Z.; Xu C.; Asara J.M.; Blenis J.; Perrimon N. 收藏  |  浏览/下载:39/0  |  提交时间:2021/05/24 |
| HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease 期刊论文 , 2020, 卷号: 369, 期号: 6500 作者: Cook S.A.; Comrie W.A.; Poli M.C.; Similuk M.; Oler A.J.; Faruqi A.J.; Kuhns D.B.; Yang S.; Vargas-Hernández A.; Carisey A.F.; Fournier B.; Anderson D.E.; Price S.; Smelkinson M.; Abou Chahla W.; Forbes L.R.; Mace E.M.; Cao T.N.; Coban-Akdemir Z.H.; Jhangiani S.N.; Muzny D.M.; Gibbs R.A.; Lupski J.R.; Orange J.S.; Cuvelier G.D.E.; Al Hassani M.; Al Kaabi N.; Al Yafei Z.; Jyonouchi S.; Raje N.; Caldwell J.W.; Huang Y.; Burkhardt J.K.; Latour S.; Chen B.; ElGhazali G.; Rao V.K.; Chinn I.K.; Lenardo M.J. 收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28 actin adenosine diphosphate ribosylation factor 1 ARF1 protein, human cytokine mammalian target of rapamycin complex 2 membrane protein NCKAP1L protein, human WASF1 protein, human WASF2 protein, human WASF3 protein, human Wiskott Aldrich syndrome protein biosynthesis CD4+ T lymphocyte cell proliferation chemistry genetics human immune deficiency immunology lymphoproliferative disease metabolism pedigree phosphorylation physiology Actins ADP-Ribosylation Factor 1 CD4-Positive T-Lymphocytes Cell Proliferation Cytokines Humans Immunologic Deficiency Syndromes Lymphoproliferative Disorders Mechanistic Target of Rapamycin Complex 2 Membrane Proteins Pedigree Phosphorylation Wiskott-Aldrich Syndrome Protein Family |
| Glucose-dependent control of leucine metabolism by leucyl-tRNA synthetase 1 期刊论文 , 2020, 卷号: 367, 期号: 6474 作者: Yoon I.; Nam M.; Kim H.K.; Moon H.-S.; Kim S.; Jang J.; Song J.A.; Jeong S.J.; Kim S.B.; Cho S.; Kim Y.; Lee J.; Yang W.S.; Yoo H.C.; Kim K.; Kim M.-S.; Yang A.; Cho K.; Park H.-S.; Hwang G.-S.; Hwang K.Y.; Han J.M.; Kim J.H.; Kim S. 收藏  |  浏览/下载:28/0  |  提交时间:2020/07/28 glucose leucine leucine transfer RNA ligase leucyl tRNA synthetase 1 mammalian target of rapamycin complex 1 S6 kinase serine threonine protein kinase ULK1 unclassified drug glucose leucine leucine transfer RNA ligase mammalian target of rapamycin complex 1 monomeric guanine nucleotide binding protein serine threonine protein kinase ULK1 catabolism cell enzyme enzyme activity glucose metabolism protein survival amino acid metabolism animal cell Article binding affinity cell survival circular dichroism controlled study embryo energy yield enzyme activity enzyme phosphorylation enzyme regulation fluorescence resonance energy transfer human human cell mouse nonhuman priority journal protein binding protein domain protein motif protein processing protein synthesis signal transduction starvation animal energy metabolism fibroblast genetics HEK293 cell line HeLa cell line lysosome metabolism phosphorylation Animals Autophagy-Related Protein-1 Homolog Energy Metabolism Fibroblasts Glucose HEK293 Cells HeLa Cells Humans Leucine Leucine-tRNA Ligase Lysosomes Mechanistic Target of Rapamycin Complex 1 Mice Monomeric GTP-Binding Proteins Phosphorylation Signal Transduction |