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湖南省生态环境厅王盛才副厅长一行到访国家气候战略中心 科技资讯
2024
收藏  |  浏览/下载:11/0  |  提交时间:2024/01/20
Nanoconfinement of microvilli alters gene expression and boosts T cell activation 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 40
作者:  Aramesh M.;  Stoycheva D.;  Sandu I.;  Ihle S.J.;  Zünd T.;  Shiu J.-Y.;  Forró C.;  Asghari M.;  Bernero M.;  Lickert S.;  Oxenius A.;  Vogel V.;  Klotzsch E.
收藏  |  浏览/下载:34/0  |  提交时间:2021/11/25
Critical role of the CD44lowCD62Llow CD8+ T cell subset in restoring antitumor immunity in aged mice 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 23
作者:  Nakajima Y.;  Chamoto K.;  Oura T.;  Honjo T.
收藏  |  浏览/下载:21/0  |  提交时间:2021/11/25
CD4+ T cells require Ikaros to inhibit their differentiation toward a pathogenic cell fate 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 17
作者:  Bernardi C.;  Maurer G.;  Ye T.;  Marchal P.;  Jost B.;  Wissler M.;  Maurer U.;  Kastner P.;  Chan S.;  Charvet C.
收藏  |  浏览/下载:33/0  |  提交时间:2021/05/24
Hierarchy of signaling thresholds downstream of the T cell receptor and the Tec kinase ITK 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 35
作者:  Gallagher M.P.;  Conley J.M.;  Vangala P.;  Garber M.;  Reboldi A.;  Berg L.J.
收藏  |  浏览/下载:28/0  |  提交时间:2022/02/22
Mitochondrial metabolism is essential for invariant natural killer T cell development and function 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 13
作者:  Weng X.;  Kumar A.;  Cao L.;  He Y.;  Morgun E.;  Visvabharathy L.;  Zhao J.;  Sena L.A.;  Weinberg S.E.;  Chandel N.S.;  Wang C.-R.
收藏  |  浏览/下载:22/0  |  提交时间:2021/05/24
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance 期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:  ElTanbouly M.A.;  Zhao Y.;  Nowak E.;  Li J.;  Schaafsma E.;  Le Mercier I.;  Ceeraz S.;  Lines J.L.;  Peng C.;  Carriere C.;  Huang X.;  Day M.;  Koehn B.;  Lee S.W.;  Morales M.S.;  Hogquist K.A.;  Jameson S.C.;  Mueller D.;  Rothstein J.;  Blazar B.R.;  Cheng C.;  Noelle R.J.
收藏  |  浏览/下载:40/0  |  提交时间:2020/07/28
cell protein  interferon  kruppel like factor 2  T lymphocyte receptor  unclassified drug  V type immunoglobulin domain containing suppressor of T cell activation protein  B7 antigen  Dies1 protein, mouse  lymphocyte antigen receptor  membrane protein  monoclonal antibody  VSIR protein, human  biological development  cell  gene expression  heterogeneity  homeostasis  immune response  immunity  tolerance  acute graft versus host disease  animal cell  animal experiment  animal model  Article  CD4+ T lymphocyte  cell death  cell expansion  cell fate  cell heterogeneity  cell loss  cell survival  controlled study  female  gene  gene deletion  homeostasis  immunological tolerance  in vivo study  long term survival  male  mouse  nonhuman  phenotype  priority journal  protein expression  protein function  rheumatoid arthritis  RNA sequencing  systemic lupus erythematosus  T lymphocyte  T lymphocyte activation  T lymphocyte subpopulation  TCR gene  upregulation  VISTA gene  animal  C57BL mouse  genetics  immunological tolerance  immunology  knockout mouse  lymphocyte activation  physiology  T lymphocyte  Mus  Animals  Antibodies, Monoclonal  B7 Antigens  Lymphocyte Activation  Membrane Proteins  Mice  Mice, Inbred C57BL  Mice, Knockout  Peripheral Tolerance  Receptors, Antigen, T-Cell  T-Lymphocytes  
CRISPR-engineered T cells in patients with refractory cancer 期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:  Stadtmauer E.A.;  Fraietta J.A.;  Davis M.M.;  Cohen A.D.;  Weber K.L.;  Lancaster E.;  Mangan P.A.;  Kulikovskaya I.;  Gupta M.;  Chen F.;  Tian L.;  Gonzalez V.E.;  Xu J.;  Jung I.-Y.;  Joseph Melenhorst J.;  Plesa G.;  Shea J.;  Matlawski T.;  Cervini A.;  Gaymon A.L.;  Desjardins S.;  Lamontagne A.;  Salas-Mckee J.;  Fesnak A.;  Siegel D.L.;  Levine B.L.;  Jadlowsky J.K.;  Young R.M.;  Chew A.;  Hwang W.-T.;  Hexner E.O.;  Carreno B.M.;  Nobles C.L.;  Bushman F.D.;  Parker K.R.;  Qi Y.;  Satpathy A.T.;  Chang H.Y.;  Zhao Y.;  Lacey S.F.;  June C.H.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
heterodimer  programmed death 1 receptor  T lymphocyte receptor alpha chain  T lymphocyte receptor beta chain  cancer  cell  gene  gene expression  genetic engineering  immunity  protein  adult  aged  Article  cancer patient  cell engineering  chromosome translocation  clinical article  clustered regularly interspaced short palindromic repeat  controlled study  CRISPR-CAS9 system  feasibility study  female  gene editing  gene expression  gene frequency  gene locus  genetic code  human  human cell  male  middle aged  myeloma  PDCD1 gene  phase 1 clinical trial  priority journal  sarcoma  T lymphocyte  TRAC gene  TRBC gene  tumor immunity  
A cell atlas of human thymic development defines T cell repertoire formation 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Park J.-E.;  Botting R.A.;  Conde C.D.;  Popescu D.-M.;  Lavaert M.;  Kunz D.J.;  Goh I.;  Stephenson E.;  Ragazzini R.;  Tuck E.;  Wilbrey-Clark A.;  Roberts K.;  Kedlian V.R.;  Ferdinand J.R.;  He X.;  Webb S.;  Maunder D.;  Vandamme N.;  Mahbubani K.T.;  Polanski K.;  Mamanova L.;  Bolt L.;  Crossland D.;  De Rita F.;  Fuller A.;  Filby A.;  Reynolds G.;  Dixon D.;  Saeb-Parsy K.;  Lisgo S.;  Henderson D.;  Vento-Tormo R.;  Bayraktar O.A.;  Barker R.A.;  Meyer K.B.;  Saeys Y.;  Bonfanti P.;  Behjati S.;  Clatworthy M.R.;  Taghon T.;  Haniffa M.;  Teichmann S.A.
收藏  |  浏览/下载:53/0  |  提交时间:2020/07/28
T lymphocyte receptor  cell component  developmental biology  differentiation  genomics  recombination  RNA  adaptive immunity  Article  CD4+ T lymphocyte  CD8+ T lymphocyte  cell fate  cell maturation  cell selection  controlled study  developmental stage  gene  gene expression  gene expression profiling  GNG4 gene  human  human cell  human tissue  lymphocyte differentiation  priority journal  protein expression  regulatory T lymphocyte  RNA sequencing  sequence analysis  T lymphocyte  T lymphocyte activation  thymic medulla  thymocyte  thymus  XCL1 gene  
Ligand-dependent downregulation of MR1 cell surface expression 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2020, 卷号: 117, 期号: 19
作者:  Salio M.;  Awad W.;  Veerapen N.;  Gonzalez-Lopez C.;  Kulicke C.;  Waithe D.;  Martens A.W.J.;  Lewinsohn D.M.;  Hobrath J.V.;  Cox L.R.;  Rossjohn J.;  Besra G.S.;  Cerundolo V.
收藏  |  浏览/下载:13/0  |  提交时间:2021/01/06