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| 湖南省生态环境厅王盛才副厅长一行到访国家气候战略中心 科技资讯 2024 收藏  |  浏览/下载:11/0  |  提交时间:2024/01/20 |
| Nanoconfinement of microvilli alters gene expression and boosts T cell activation 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 40 作者: Aramesh M.; Stoycheva D.; Sandu I.; Ihle S.J.; Zünd T.; Shiu J.-Y.; Forró C.; Asghari M.; Bernero M.; Lickert S.; Oxenius A.; Vogel V.; Klotzsch E. 收藏  |  浏览/下载:34/0  |  提交时间:2021/11/25 |
| Critical role of the CD44lowCD62Llow CD8+ T cell subset in restoring antitumor immunity in aged mice 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 23 作者: Nakajima Y.; Chamoto K.; Oura T.; Honjo T. 收藏  |  浏览/下载:21/0  |  提交时间:2021/11/25 |
| CD4+ T cells require Ikaros to inhibit their differentiation toward a pathogenic cell fate 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 17 作者: Bernardi C.; Maurer G.; Ye T.; Marchal P.; Jost B.; Wissler M.; Maurer U.; Kastner P.; Chan S.; Charvet C. 收藏  |  浏览/下载:33/0  |  提交时间:2021/05/24 |
| Hierarchy of signaling thresholds downstream of the T cell receptor and the Tec kinase ITK 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 35 作者: Gallagher M.P.; Conley J.M.; Vangala P.; Garber M.; Reboldi A.; Berg L.J. 收藏  |  浏览/下载:28/0  |  提交时间:2022/02/22 |
| Mitochondrial metabolism is essential for invariant natural killer T cell development and function 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 13 作者: Weng X.; Kumar A.; Cao L.; He Y.; Morgun E.; Visvabharathy L.; Zhao J.; Sena L.A.; Weinberg S.E.; Chandel N.S.; Wang C.-R. 收藏  |  浏览/下载:22/0  |  提交时间:2021/05/24 |
| VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance 期刊论文 , 2020, 卷号: 367, 期号: 6475 作者: ElTanbouly M.A.; Zhao Y.; Nowak E.; Li J.; Schaafsma E.; Le Mercier I.; Ceeraz S.; Lines J.L.; Peng C.; Carriere C.; Huang X.; Day M.; Koehn B.; Lee S.W.; Morales M.S.; Hogquist K.A.; Jameson S.C.; Mueller D.; Rothstein J.; Blazar B.R.; Cheng C.; Noelle R.J. 收藏  |  浏览/下载:40/0  |  提交时间:2020/07/28 cell protein interferon kruppel like factor 2 T lymphocyte receptor unclassified drug V type immunoglobulin domain containing suppressor of T cell activation protein B7 antigen Dies1 protein, mouse lymphocyte antigen receptor membrane protein monoclonal antibody VSIR protein, human biological development cell gene expression heterogeneity homeostasis immune response immunity tolerance acute graft versus host disease animal cell animal experiment animal model Article CD4+ T lymphocyte cell death cell expansion cell fate cell heterogeneity cell loss cell survival controlled study female gene gene deletion homeostasis immunological tolerance in vivo study long term survival male mouse nonhuman phenotype priority journal protein expression protein function rheumatoid arthritis RNA sequencing systemic lupus erythematosus T lymphocyte T lymphocyte activation T lymphocyte subpopulation TCR gene upregulation VISTA gene animal C57BL mouse genetics immunological tolerance immunology knockout mouse lymphocyte activation physiology T lymphocyte Mus Animals Antibodies, Monoclonal B7 Antigens Lymphocyte Activation Membrane Proteins Mice Mice, Inbred C57BL Mice, Knockout Peripheral Tolerance Receptors, Antigen, T-Cell T-Lymphocytes |
| CRISPR-engineered T cells in patients with refractory cancer 期刊论文 , 2020, 卷号: 367, 期号: 6481 作者: Stadtmauer E.A.; Fraietta J.A.; Davis M.M.; Cohen A.D.; Weber K.L.; Lancaster E.; Mangan P.A.; Kulikovskaya I.; Gupta M.; Chen F.; Tian L.; Gonzalez V.E.; Xu J.; Jung I.-Y.; Joseph Melenhorst J.; Plesa G.; Shea J.; Matlawski T.; Cervini A.; Gaymon A.L.; Desjardins S.; Lamontagne A.; Salas-Mckee J.; Fesnak A.; Siegel D.L.; Levine B.L.; Jadlowsky J.K.; Young R.M.; Chew A.; Hwang W.-T.; Hexner E.O.; Carreno B.M.; Nobles C.L.; Bushman F.D.; Parker K.R.; Qi Y.; Satpathy A.T.; Chang H.Y.; Zhao Y.; Lacey S.F.; June C.H. 收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28 heterodimer programmed death 1 receptor T lymphocyte receptor alpha chain T lymphocyte receptor beta chain cancer cell gene gene expression genetic engineering immunity protein adult aged Article cancer patient cell engineering chromosome translocation clinical article clustered regularly interspaced short palindromic repeat controlled study CRISPR-CAS9 system feasibility study female gene editing gene expression gene frequency gene locus genetic code human human cell male middle aged myeloma PDCD1 gene phase 1 clinical trial priority journal sarcoma T lymphocyte TRAC gene TRBC gene tumor immunity |
| A cell atlas of human thymic development defines T cell repertoire formation 期刊论文 , 2020, 卷号: 367, 期号: 6480 作者: Park J.-E.; Botting R.A.; Conde C.D.; Popescu D.-M.; Lavaert M.; Kunz D.J.; Goh I.; Stephenson E.; Ragazzini R.; Tuck E.; Wilbrey-Clark A.; Roberts K.; Kedlian V.R.; Ferdinand J.R.; He X.; Webb S.; Maunder D.; Vandamme N.; Mahbubani K.T.; Polanski K.; Mamanova L.; Bolt L.; Crossland D.; De Rita F.; Fuller A.; Filby A.; Reynolds G.; Dixon D.; Saeb-Parsy K.; Lisgo S.; Henderson D.; Vento-Tormo R.; Bayraktar O.A.; Barker R.A.; Meyer K.B.; Saeys Y.; Bonfanti P.; Behjati S.; Clatworthy M.R.; Taghon T.; Haniffa M.; Teichmann S.A. 收藏  |  浏览/下载:53/0  |  提交时间:2020/07/28 T lymphocyte receptor cell component developmental biology differentiation genomics recombination RNA adaptive immunity Article CD4+ T lymphocyte CD8+ T lymphocyte cell fate cell maturation cell selection controlled study developmental stage gene gene expression gene expression profiling GNG4 gene human human cell human tissue lymphocyte differentiation priority journal protein expression regulatory T lymphocyte RNA sequencing sequence analysis T lymphocyte T lymphocyte activation thymic medulla thymocyte thymus XCL1 gene |
| Ligand-dependent downregulation of MR1 cell surface expression 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2020, 卷号: 117, 期号: 19 作者: Salio M.; Awad W.; Veerapen N.; Gonzalez-Lopez C.; Kulicke C.; Waithe D.; Martens A.W.J.; Lewinsohn D.M.; Hobrath J.V.; Cox L.R.; Rossjohn J.; Besra G.S.; Cerundolo V. 收藏  |  浏览/下载:13/0  |  提交时间:2021/01/06 |