|
已选(0)清除
条数/页： 排序方式： |
| CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者: Muendlein H.I.; Jetton D.; Connolly W.M.; Eidell K.P.; Magri Z.; Smirnova I.; Poltorak A.
  收藏 | 浏览/下载：38/0 | 提交时间：2020/07/28
FLICE inhibitory protein interleukin 1beta lipopolysaccharide messenger RNA succinate dehydrogenase (ubiquinone) Casp1 protein, mouse caspase 8 Cflar protein, mouse cryopyrin FLICE inhibitory protein IL1B protein, mouse inflammasome interleukin 1beta interleukin 1beta converting enzyme lipopolysaccharide succinate dehydrogenase (ubiquinone) cell enzyme activity inhibition maturation protein animal cell animal experiment Article bone marrow derived macrophage cell death cell protection complex formation controlled study cytokine release in vitro study inflammation mouse nonhuman priority journal protein analysis protein degradation protein function protein interaction pyroptosis animal gene knockdown genetics immunology macrophage macrophage activation metabolism physiology Murinae Animals CASP8 and FADD-Like Apoptosis Regulating Protein Caspase 1 Caspase 8 Electron Transport Complex II Gene Knockdown Techniques Inflammasomes Interleukin-1beta Lipopolysaccharides Macrophage Activation Macrophages Mice NLR Family, Pyrin Domain-Containing 3 Protein Pyroptosis |
| Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat 期刊论文
, 2020, 卷号: 368, 期号: 6493
作者: Wang H.; Sun S.; Ge W.; Zhao L.; Hou B.; Wang K.; Lyu Z.; Chen L.; Xu S.; Guo J.; Li M.; Su P.; Li X.; Wang G.; Bo C.; Fang X.; Zhuang W.; Cheng X.; Wu J.; Dong L.; Chen W.; Li W.; Xiao G.; Zhao J.; Hao Y.; Xu Y.; Gao Y.; Liu W.; Liu Y.; Yin H.; Li J.; Li X.; Zhao Y.; Wang X.; Ni F.; Ma X.; Li A.; Xu S.S.; Bai G.; Nevo E.; Gao C.; Ohm H.; Kong L.
收藏 | 浏览/下载：49/0 | 提交时间：2020/07/28
fungus gene transfer genome germplasm toxin wheat Fungi Fusarium Lophopyrum elongatum Triticum aestivum glutathione transferase disease resistance Epichloe Fusarium genetics horizontal gene transfer microbiology molecular cloning pathogenicity plant breeding plant disease Poaceae wheat Cloning, Molecular Disease Resistance Epichloe Fusarium Gene Transfer, Horizontal Glutathione Transferase Plant Breeding Plant Diseases Poaceae Triticum |
| Gas chromatography-mass spectrometry analyses of encapsulated stable perovskite solar cells 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者: Shi L.; Bucknall M.P.; Young T.L.; Zhang M.; Hu L.; Bing J.; Lee D.S.; Kim J.; Wu T.; Takamure N.; McKenzie D.R.; Huang S.; Green M.A.; Ho-Baillie A.W.Y.
收藏 | 浏览/下载：41/0 | 提交时间：2020/07/28
cation encapsulation energy efficiency fuel cell gas chromatography mass spectrometry perovskite solar power temperature effect |
| Hydrophobic zeolite modification for in situ peroxide formation in methane oxidation to methanol 期刊论文
, 2020, 卷号: 367, 期号: 6474
作者: Jin Z.; Wang L.; Zuidema E.; Mondal K.; Zhang M.; Zhang J.; Wang C.; Meng X.; Yang H.; Mesters C.; Xiao F.-S.
收藏 | 浏览/下载：136/0 | 提交时间：2020/07/28
aluminosilicate zeolite carbon dioxide carbon monoxide formaldehyde gold nanoparticle hydrogen peroxide methane methanol palladium nanoparticle silicon dioxide unclassified drug zeolite aluminosilicate catalyst diffusion hydrogen hydrogen peroxide methane methanol oxidation oxygen Article carbon nuclear magnetic resonance catalyst chemical reaction concentration (parameter) diffusion energy dispersive X ray spectroscopy Fourier transform infrared spectroscopy hydrophobicity isotherm nanoencapsulation nuclear magnetic resonance oxidation priority journal scanning electron microscopy silicon nuclear magnetic resonance stoichiometry synthesis transmission electron microscopy X ray crystallography |
| A general method to synthesize and sinter bulk ceramics in seconds 期刊论文
, 2020, 卷号: 368, 期号: 6490
作者: Wang C.; Ping W.; Bai Q.; Cui H.; Hensleigh R.; Wang R.; Brozena A.H.; Xu Z.; Dai J.; Pei Y.; Zheng C.; Pastel G.; Gao J.; Wang X.; Wang H.; Zhao J.-C.; Yang B.; Zheng X.; Luo J.; Mo Y.; Dunn B.; Hu L.
收藏 | 浏览/下载：26/0 | 提交时间：2020/07/28
electrolyte ceramics chemical composition computer system electrolyte heating mechanical property radiative transfer sinter volatile element Article ceramics chemical structure high temperature procedures high throughput screening materials testing priority journal radiation solid state synthesis ultrafast high temperature sintering |
| Old carbon reservoirs were not important in the deglacial methane budget 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者: Dyonisius M.N.; Petrenko V.V.; Smith A.M.; Hua Q.; Yang B.; Schmitt J.; Beck J.; Seth B.; Bock M.; Hmiel B.; Vimont I.; Menking J.A.; Shackleton S.A.; Baggenstos D.; Bauska T.K.; Rhodes R.H.; Sperlich P.; Beaudette R.; Harth C.; Kalk M.; Brook E.J.; Fischer H.; Severinghaus J.P.; Weiss R.F.
收藏 | 浏览/下载：124/0 | 提交时间：2020/07/28
carbon carbon 14 carbon dioxide carbon monoxide deuterium hydrocarbon hydrogen methane nitrogen oxide biomass burning carbon deglaciation global warming Holocene methane permafrost reservoir aerosol air pollution Article atmosphere biomass carbon cycle carbon footprint deglaciation environmental temperature Holocene ice core record ice sheet lake landslide moisture permafrost priority journal sediment soil thawing |
| Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者: Wilmes S.; Hafer M.; Vuorio J.; Tucker J.A.; Winkelmann H.; Löchte S.; Stanly T.A.; Pulgar Prieto K.D.; Poojari C.; Sharma V.; Richter C.P.; Kurre R.; Hubbard S.R.; Christopher Garcia K.; Moraga I.; Vattulainen I.; Hitchcock I.S.; Piehler J.
收藏 | 浏览/下载：35/0 | 提交时间：2020/07/28
cytokine receptor homodimer Janus kinase 2 ligand oncoprotein cancer enzyme enzyme activity membrane molecular analysis mutation protein activation analysis Article cell membrane computer model controlled study dimerization fluorescence microscopy gene mutation HeLa cell line molecular dynamics mutant oncogene priority journal protein domain protein interaction quantitative analysis signal transduction |
| Na+-gated water-conducting nanochannels for boosting CO2 conversion to liquid fuels 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者: Li H.; Qiu C.; Ren S.; Dong Q.; Zhang S.; Zhou F.; Liang X.; Wang J.; Li S.; Yu M.
收藏 | 浏览/下载：32/0 | 提交时间：2020/07/28
aluminum carbon dioxide carbon monoxide copper fuel hydrogen methanol nanochannel sodium ion water zeolite zinc carbon dioxide high temperature hydraulic conductivity membrane nanocomposite nanotechnology separation sodium thermodynamics adsorption Article Brunauer Emmett Teller catalyst chemical composition controlled study crystal density functional theory energy dispersive X ray spectroscopy gas hydrogenation measurement priority journal scanning electron microscopy surface area water permeability |
| Ultrafast vector imaging of plasmonic skyrmion dynamics with deep subwavelength resolution 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者: Davis T.J.; Janoschka D.; Dreher P.; Frank B.; Meyer zu Heringdorf F.J.; Giessen H.
收藏 | 浏览/下载：32/0 | 提交时间：2020/07/28
electric field electromagnetic method imaging method optical method spatial resolution wavelength absorption Article controlled study electric field electromagnetism molecular stability photoelectron spectroscopy polarization priority journal solid state spatiotemporal analysis surface charge surface plasmon resonance |
| Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者: Dai W.; Zhang B.; Jiang X.-M.; Su H.; Li J.; Zhao Y.; Xie X.; Jin Z.; Peng J.; Liu F.; Li C.; Li Y.; Bai F.; Wang H.; Cheng X.; Cen X.; Hu S.; Yang X.; Wang J.; Liu X.; Xiao G.; Jiang H.; Rao Z.; Zhang L.-K.; Xu Y.; Yang H.; Liu H.
收藏 | 浏览/下载：36/0 | 提交时间：2020/07/28
aldehyde antimicrobial activity drug enzyme activity infectivity inhibitor reaction kinetics viral disease Coronavirus SARS coronavirus 3C-like proteinase, Coronavirus antivirus agent cysteine proteinase viral protein animal Betacoronavirus chemical structure chemistry Chlorocebus aethiops Coronavirus infection dog drug design drug effect enzyme active site enzymology female human male mouse pandemic preclinical study protein tertiary structure Sprague Dawley rat toxicity testing Vero cell line virus pneumonia Animals Antiviral Agents Betacoronavirus Catalytic Domain Chlorocebus aethiops Coronavirus Infections Cysteine Endopeptidases Dogs Drug Design Drug Evaluation, Preclinical Female Humans Male Mice Molecular Structure Pandemics Pneumonia, Viral Protein Structure, Tertiary Rats, Sprague-Dawley Toxicity Tests Vero Cells Viral Nonstructural Proteins |
| T cells with dysfunctional mitochondria induce multimorbidity and premature senescence 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者: Desdín-Micó G.; Soto-Heredero G.; Aranda J.F.; Oller J.; Carrasco E.; Gabandé-Rodríguez E.; Blanco E.M.; Alfranca A.; Cussó L.; Desco M.; Ibañez B.; Gortazar A.R.; Fernández-Marcos P.; Navarro M.N.; Hernaez B.; Alcamí A.; Baixauli F.; Mittelbrunn M.
收藏 | 浏览/下载：36/0 | 提交时间：2020/07/28
cardiovascular disease enzyme activity gene expression metabolism mitochondrial DNA morbidity senescence tumor Mus DNA binding protein mitochondrial protein mitochondrial transcription factor A nicotinamide adenine dinucleotide transcription factor tumor necrosis factor animal cytokine release syndrome female fitness gene deletion genetics immunology inflammation longevity male metabolism mitochondrion mouse multiple chronic conditions mutant mouse strain premature aging T lymphocyte ultrastructure Aging, Premature Animals Cytokine Release Syndrome DNA-Binding Proteins Female Gene Deletion Inflammation Longevity Male Mice Mice, Mutant Strains Mitochondria Mitochondrial Proteins Multimorbidity NAD Physical Fitness T-Lymphocytes Transcription Factors Tumor Necrosis Factor-alpha |
| h/e oscillations in interlayer transport of delafossites 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者: Putzke C.; Bachmann M.D.; McGuinness P.; Zhakina E.; Sunko V.; Konczykowski M.; Oka T.; Moessner R.; Stern A.; König M.; Khim S.; Mackenzie A.P.; Moll P.J.W.
收藏 | 浏览/下载：30/0 | 提交时间：2020/07/28
electron experimental study inorganic compound microstructure oscillation separation temperature effect article magnetic field oscillation |
| Chloride-mediated selective electrosynthesis of ethylene and propylene oxides at high current density 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者: Leow W.R.; Lum Y.; Ozden A.; Wang Y.; Nam D.-H.; Chen B.; Wicks J.; Zhuang T.-T.; Li F.; Sinton D.; Sargent E.H.
收藏 | 浏览/下载：31/0 | 提交时间：2020/07/28
alternative energy chloride electrochemical method electrochemistry ethylene manufacturing oxidation oxide plastic polymer |
| Membrane-proximal F-actin restricts local membrane protrusions and directs cell migration 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者: Bisaria A.; Hayer A.; Garbett D.; Cohen D.; Meyer T.
收藏 | 浏览/下载：31/0 | 提交时间：2020/07/28
cell component concentration (composition) membrane polymerization protein actin green fluorescent protein cell membrane cell motion cell polarity cell surface chemistry genetics human metabolism umbilical vein endothelial cell Actins Cell Membrane Cell Movement Cell Polarity Cell Surface Extensions Green Fluorescent Proteins Human Umbilical Vein Endothelial Cells Humans |
| Temporal integration of mitogen history in mother cells controls proliferation of daughter cells 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者: Min M.; Rong Y.; Tian C.; Spencer S.L.
收藏 | 浏览/下载：22/0 | 提交时间：2020/07/28
cyclin D mitogen activated protein kinase kinase mitogenic agent cell cycle G1 phase cell cycle G2 phase cell proliferation genetics human metabolism physiology protein synthesis signal transduction stem cell Cell Proliferation Cyclin D G1 Phase G2 Phase Humans Mitogen-Activated Protein Kinase Kinases Mitogens Protein Biosynthesis Signal Transduction Stem Cells |
| Plastic rain in protected areas of the United States 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者: Brahney J.; Hallerud M.; Heim E.; Hahnenberger M.; Sukumaran S.
收藏 | 浏览/下载：20/0 | 提交时间：2020/07/28
plastic rain environmental protection pollution soil pollutant United States water pollutant wind Conservation of Natural Resources Environmental Pollution Plastics Rain Soil Pollutants United States Water Pollutants, Chemical Wind |
| Computing cancer's weak spots 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者: Khamsi R.
收藏 | 浏览/下载：35/0 | 提交时间：2020/07/28
ruxolitinib STAT3 protein antineoplastic agent transcription factor algorithm cancer computer simulation disease treatment drug development medicine Article cancer cell cancer radiotherapy enzyme inhibition gene activity gene expression regulation gene interaction gene mutation gene repression gene targeting human laboratory test malignant neoplasm molecular dynamics nonhuman oncologist priority journal RNA sequencing algorithm genetics mutation neoplasm personalized medicine procedures systems biology Algorithms Antineoplastic Agents Humans Mutation Neoplasms Precision Medicine Systems Biology Transcription Factors |
| Structure of the RNA-dependent RNA polymerase from COVID-19 virus 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者: Gao Y.; Yan L.; Huang Y.; Liu F.; Zhao Y.; Cao L.; Wang T.; Sun Q.; Ming Z.; Zhang L.; Ge J.; Zheng L.; Zhang Y.; Wang H.; Zhu Y.; Zhu C.; Hu T.; Hua T.; Zhang B.; Yang X.; Li J.; Yang H.; Liu Z.; Xu W.; Guddat L.W.; Wang Q.; Lou Z.; Rao Z.
收藏 | 浏览/下载：40/0 | 提交时间：2020/07/28
comparative study drug electron microscopy enzyme enzyme activity RNA virus Coronavirus SARS coronavirus adenosine phosphate alanine antivirus agent NSP7 protein, SARS-CoV-2 NSP8 protein, SARS-CoV-2 remdesivir RNA directed RNA polymerase RNA-dependent RNA polymerase, coronavirus viral protein beta sheet Betacoronavirus chemistry cryoelectron microscopy drug design enzyme active site enzymology metabolism molecular model protein domain ultrastructure Adenosine Monophosphate Alanine Antiviral Agents Betacoronavirus Catalytic Domain Cryoelectron Microscopy Drug Design Models, Molecular Protein Conformation, beta-Strand Protein Domains RNA Replicase Viral Nonstructural Proteins |
| Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者: Guthrie L.M.; Soma S.; Yuan S.; Silva A.; Zulkifli M.; Snavely T.C.; Greene H.F.; Nunez E.; Lynch B.; de Ville C.; Shanbhag V.; Lopez F.R.; Acharya A.; Petris M.J.; Kim B.-E.; Gohil V.M.; Sacchettini J.C.
收藏 | 浏览/下载：28/0 | 提交时间：2020/07/28
copper copper zinc superoxide dismutase cytochrome c oxidase dopamine beta monooxygenase elesclomol monophenol monooxygenase protein lysine 6 oxidase copper cytochrome c oxidase elesclomol hydrazine derivative copper cytochrome enzyme enzyme activity mitochondrion mortality mutation pathology rodent survival animal cell animal experiment animal model animal tissue Article cohort analysis controlled study disease severity drug mechanism Golgi complex H9c2(2-1) cell line in vivo study male Menkes syndrome mitochondrial dynamics mortality rate mouse nerve degeneration nonhuman priority journal secretory pathway survival rate animal brain cell line degenerative disease disease model drug effect genetics knockout mouse Menkes syndrome metabolism mitochondrion pathology rat transport at the cellular level Murinae Mus Animals Biological Transport Brain Cell Line Copper Copper Transporter 1 Disease Models, Animal Electron Transport Complex IV Hydrazines Male Menkes Kinky Hair Syndrome Mice Mice, Knockout Mitochondria Neurodegenerative Diseases Rats |
| Emergence of complexity in hierarchically organized chiral particles 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者: Jiang W.; Qu Z.-B.; Kumar P.; Vecchio D.; Wang Y.; Ma Y.; Bahng J.H.; Bernardino K.; Gomes W.R.; Colombari F.M.; Lozada-Blanco A.; Veksler M.; Marino E.; Simon A.; Murray C.; Muniz S.R.; de Moura A.F.; Kotov N.A.
收藏 | 浏览/下载：27/0 | 提交时间：2020/07/28
biomaterial cetrimide cysteine gold nanocomposite nanoparticle chemical property colloid complexation complexity composite ligand nanoparticle physicochemical property symmetry adsorption Article biomineralization chemical structure chirality circular dichroism coccolith enthalpy entropy ionic strength molecular weight particle size priority journal spike wave thermodynamics zeta potential Humulus |
