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Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat 期刊论文
, 2020, 卷号: 368, 期号: 6493
作者:  Wang H.;  Sun S.;  Ge W.;  Zhao L.;  Hou B.;  Wang K.;  Lyu Z.;  Chen L.;  Xu S.;  Guo J.;  Li M.;  Su P.;  Li X.;  Wang G.;  Bo C.;  Fang X.;  Zhuang W.;  Cheng X.;  Wu J.;  Dong L.;  Chen W.;  Li W.;  Xiao G.;  Zhao J.;  Hao Y.;  Xu Y.;  Gao Y.;  Liu W.;  Liu Y.;  Yin H.;  Li J.;  Li X.;  Zhao Y.;  Wang X.;  Ni F.;  Ma X.;  Li A.;  Xu S.S.;  Bai G.;  Nevo E.;  Gao C.;  Ohm H.;  Kong L.
收藏  |  浏览/下载：49/0  |  提交时间：2020/07/28
fungus  gene transfer  genome  germplasm  toxin  wheat  Fungi  Fusarium  Lophopyrum elongatum  Triticum aestivum  glutathione transferase  disease resistance  Epichloe  Fusarium  genetics  horizontal gene transfer  microbiology  molecular cloning  pathogenicity  plant breeding  plant disease  Poaceae  wheat  Cloning, Molecular  Disease Resistance  Epichloe  Fusarium  Gene Transfer, Horizontal  Glutathione Transferase  Plant Breeding  Plant Diseases  Poaceae  Triticum  
Structure of the RNA-dependent RNA polymerase from COVID-19 virus 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Gao Y.;  Yan L.;  Huang Y.;  Liu F.;  Zhao Y.;  Cao L.;  Wang T.;  Sun Q.;  Ming Z.;  Zhang L.;  Ge J.;  Zheng L.;  Zhang Y.;  Wang H.;  Zhu Y.;  Zhu C.;  Hu T.;  Hua T.;  Zhang B.;  Yang X.;  Li J.;  Yang H.;  Liu Z.;  Xu W.;  Guddat L.W.;  Wang Q.;  Lou Z.;  Rao Z.
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/28
comparative study  drug  electron microscopy  enzyme  enzyme activity  RNA  virus  Coronavirus  SARS coronavirus  adenosine phosphate  alanine  antivirus agent  NSP7 protein, SARS-CoV-2  NSP8 protein, SARS-CoV-2  remdesivir  RNA directed RNA polymerase  RNA-dependent RNA polymerase, coronavirus  viral protein  beta sheet  Betacoronavirus  chemistry  cryoelectron microscopy  drug design  enzyme active site  enzymology  metabolism  molecular model  protein domain  ultrastructure  Adenosine Monophosphate  Alanine  Antiviral Agents  Betacoronavirus  Catalytic Domain  Cryoelectron Microscopy  Drug Design  Models, Molecular  Protein Conformation, beta-Strand  Protein Domains  RNA Replicase  Viral Nonstructural Proteins  
Nearly quantized conductance plateau of vortex zero mode in an iron-based superconductor 期刊论文
, 2020, 卷号: 367, 期号: 6474
作者:  Zhu S.;  Kong L.;  Cao L.;  Chen H.;  Papaj M.;  Du S.;  Xing Y.;  Liu W.;  Wang D.;  Shen C.;  Yang F.;  Schneeloch J.;  Zhong R.;  Gu G.;  Fu L.;  Zhang Y.-Y.;  Ding H.;  Gao H.-J.
收藏  |  浏览/下载：32/0  |  提交时间：2020/07/28
iron  equipment  iron  plateau  vortex  Article  controlled study  electric conductance  energy  fractional quasiparticle  mathematical computing  non Abelian braiding statistics  particle antiparticle equivalence  physical parameters  priority journal  quantum computing  scanning tunneling spectroscopy  statistical analysis  Abelia  Majorana  
The genetic architecture of the human cerebral cortex 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Grasby K.L.;  Jahanshad N.;  Painter J.N.;  Colodro-Conde L.;  Bralten J.;  Hibar D.P.;  Lind P.A.;  Pizzagalli F.;  Ching C.R.K.;  McMahon M.A.B.;  Shatokhina N.;  Zsembik L.C.P.;  Thomopoulos S.I.;  Zhu A.H.;  Strike L.T.;  Agartz I.;  Alhusaini S.;  Almeida M.A.A.;  Alnæs D.;  Amlien I.K.;  Andersson M.;  Ard T.;  Armstrong N.J.;  Ashley-Koch A.;  Atkins J.R.;  Bernard M.;  Brouwer R.M.;  Buimer E.E.L.;  Bülow R.;  Bürger C.;  Cannon D.M.;  Chakravarty M.;  Chen Q.;  Cheung J.W.;  Couvy-Duchesne B.;  Dale A.M.;  Dalvie S.;  de Araujo T.K.;  de Zubicaray G.I.;  de Zwarte S.M.C.;  den Braber A.;  Doan N.T.;  Dohm K.;  Ehrlich S.;  Engelbrecht H.-R.;  Erk S.;  Fan C.C.;  Fedko I.O.;  Foley S.F.;  Ford J.M.;  Fukunaga M.;  Garrett M.E.;  Ge T.;  Giddaluru S.;  Goldman A.L.;  Green M.J.;  Groenewold N.A.;  Grotegerd D.;  Gurholt T.P.;  Gutman B.A.;  Hansell N.K.;  Harris M.A.;  Harrison M.B.;  Haswell C.C.;  Hauser M.;  Herms S.;  Heslenfeld D.J.;  Ho N.F.;  Hoehn D.;  Hoffmann P.;  Holleran L.;  Hoogman M.;  Hottenga J.-J.;  Ikeda M.;  Janowitz D.;  Jansen I.E.;  Jia T.;  Jockwitz C.;  Kanai R.;  Karama S.;  Kasperaviciute D.;  Kaufmann T.;  Kelly S.;  Kikuchi M.;  Klein M.;  Knapp M.;  Knodt A.R.;  Krämer B.;  Lam M.;  Lancaster T.M.;  Lee P.H.;  Lett T.A.;  Lewis L.B.;  Lopes-Cendes I.;  Luciano M.;  Macciardi F.;  Marquand A.F.;  Mathias S.R.;  Melzer T.R.;  Milaneschi Y.;  Mirza-Schreiber N.;  Moreira J.C.V.;  Mühleisen T.W.;  Müller-Myhsok B.;  Najt P.;  Nakahara S.;  Nho K.;  Olde Loohuis L.M.;  Orfanos D.P.;  Pearson J.F.;  Pitcher T.L.;  Pütz B.;  Quidé Y.;  Ragothaman A.;  Rashid F.M.;  Reay W.R.;  Redlich R.;  Reinbold C.S.;  Repple J.;  Richard G.;  Riedel B.C.;  Risacher S.L.;  Rocha C.S.;  Mota N.R.;  Salminen L.;  Saremi A.;  Saykin A.J.;  Schlag F.;  Schmaal L.;  Schofield P.R.;  Secolin R.;  Shapland C.Y.;  Shen L.;  Shin J.;  Shumskaya E.;  Sønderby I.E.;  Sprooten E.;  Tansey K.E.;  Teumer A.;  Thalamuthu A.;  Tordesillas-Gutiérrez D.;  Turner J.A.;  Uhlmann A.;  Vallerga C.L.;  van der Meer D.;  van Donkelaar M.M.J.;  van Eijk L.;  van Erp T.G.M.;  van Haren N.E.M.;  van Rooij D.;  van Tol M.-J.;  Veldink J.H.;  Verhoef E.;  Walton E.;  Wang M.;  Wang Y.;  Wardlaw J.M.;  Wen W.;  Westlye L.T.;  Whelan C.D.;  Witt S.H.;  Wittfeld K.;  Wolf C.;  Wolfers T.;  Wu J.Q.;  Yasuda C.L.;  Zaremba D.;  Zhang Z.;  Zwiers M.P.;  Artiges E.;  Assareh A.A.;  Ayesa-Arriola R.;  Belger A.;  Brandt C.L.;  Brown G.G.;  Cichon S.;  Curran J.E.;  Davies G.E.;  Degenhardt F.;  Dennis M.F.;  Dietsche B.;  Djurovic S.;  Doherty C.P.;  Espiritu R.;  Garijo D.;  Gil Y.;  Gowland P.A.;  Green R.C.;  Häusler A.N.;  Heindel W.;  Ho B.-C.;  Hoffmann W.U.;  Holsboer F.;  Homuth G.;  Hosten N.;  Jack C.R.;  Jang M.;  Jansen A.;  Kimbrel N.A.;  Kolskår K.;  Koops S.;  Krug A.;  Lim K.O.;  Luykx J.J.;  Mathalon D.H.;  Mather K.A.;  Mattay V.S.;  Matthews S.;  van Son J.M.;  McEwen S.C.;  Melle I.;  Morris D.W.;  Mueller B.A.;  Nauck M.;  Nordvik J.E.;  Nöthen M.M.;  O'Leary D.S.;  Opel N.;  Martinot M.-L.P.;  Bruce Pike G.;  Preda A.;  Quinlan E.B.;  Rasser P.E.;  Ratnakar V.;  Reppermund S.;  Steen V.M.;  Tooney P.A.;  Torres F.R.;  Veltman D.J.;  Voyvodic J.T.;  Whelan R.;  White T.;  Yamamori H.;  Adams H.H.H.;  Bis J.C.;  Debette S.;  Decarli C.;  Fornage M.;  Gudnason V.;  Hofer E.;  Arfan Ikram M.;  Launer L.;  Longstreth W.T.;  Lopez O.L.;  Mazoyer B.;  Mosley T.H.;  Roshchupkin G.V.;  Satizabal C.L.;  Schmidt R.;  Seshadri S.;  Yang Q.;  Alvim M.K.M.;  Ames D.;  Anderson T.J.;  Andreassen O.A.;  Arias-Vasquez A.;  Bastin M.E.;  Baune B.T.;  Beckham J.C.;  Blangero J.;  Boomsma D.I.;  Brodaty H.;  Brunner H.G.;  Buckner R.L.;  Buitelaar J.K.;  Bustillo J.R.;  Cahn W.;  Cairns M.J.;  Calhoun V.;  Carr V.J.;  Caseras X.;  Caspers S.;  Cavalleri G.L.;  Cendes F.;  Corvin A.;  Crespo-Facorro B.;  Dalrymple-Alford J.C.;  Dannlowski U.;  de Geus E.J.C.;  Deary I.J.;  Delanty N.;  Depondt C.;  Desrivières S.;  Donohoe G.;  Espeseth T.;  Fernández G.;  Fisher S.E.;  Flor H.;  Forstner A.J.;  Francks C.;  Franke B.;  Glahn D.C.;  Gollub R.L.;  Grabe H.J.;  Gruber O.;  Håberg A.K.;  Hariri A.R.;  Hartman C.A.;  Hashimoto R.;  Heinz A.;  Henskens F.A.;  Hillegers M.H.J.;  Hoekstra P.J.;  Holmes A.J.;  Elliot Hong L.;  Hopkins W.D.;  Hulshoff Pol H.E.;  Jernigan T.L.;  Jönsson E.G.;  Kahn R.S.;  Kennedy M.A.;  Kircher T.T.J.;  Kochunov P.;  Kwok J.B.J.;  Le Hellard S.;  Loughland C.M.;  Martin N.G.;  Martinot J.-L.;  McDonald C.;  McMahon K.L.;  Meyer-Lindenberg A.;  Michie P.T.;  Morey R.A.;  Mowry B.;  Nyberg L.;  Oosterlaan J.;  Ophoff R.A.;  Pantelis C.;  Paus T.;  Pausova Z.;  Penninx B.W.J.H.;  Polderman T.J.C.;  Posthuma D.;  Rietschel M.;  Roffman J.L.;  Rowland L.M.;  Sachdev P.S.;  Sämann P.G.;  Schall U.;  Schumann G.;  Scott R.J.;  Sim K.;  Sisodiya S.M.;  Smoller J.W.;  Sommer I.E.;  Pourcain B.S.;  Stein D.J.;  Toga A.W.;  Trollor J.N.;  van der Wee N.J.A.;  van't Ent D.;  Völzke H.;  Walter H.;  Weber B.;  Weinberger D.R.;  Wright M.J.;  Zhou J.;  Stein J.L.;  Thompson P.M.;  Medland S.E.;  Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)-Genetics working group
收藏  |  浏览/下载：47/0  |  提交时间：2020/07/28
brain  genetic analysis  meta-analysis  resonance  signaling  surface area  Article  bioinformatics  brain cortex  brain function  brain region  brain tissue  cortical thickness (brain)  educational status  evidence based medicine  gene control  gene locus  genetic association  genetic correlation  genetic variability  genome-wide association study  human  human genetics  priority journal  surface area  tissue structure  Wnt signaling  anatomy and histology  attention deficit disorder  brain cortex  brain mapping  cognition  genetic variation  genetics  meta analysis  nuclear magnetic resonance imaging  organ size  Parkinson disease  Attention Deficit Disorder with Hyperactivity  Brain Mapping  Cerebral Cortex  Cognition  Genetic Loci  Genetic Variation  Genome-Wide Association Study  Humans  Magnetic Resonance Imaging  Organ Size  Parkinson Disease  
Structural basis of Gs and Gi recognition by the human glucagon receptor 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Qiao A.;  Han S.;  Li X.;  Li Z.;  Zhao P.;  Dai A.;  Chang R.;  Tai L.;  Tan Q.;  Chu X.;  Ma L.;  Thorsen T.S.;  Reedtz-Runge S.;  Yang D.;  Wang M.-W.;  Sexton P.M.;  Wootten D.;  Sun F.;  Zhao Q.;  Wu B.
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/28
cyclic AMP  glucagon  glucagon receptor  inhibitory guanine nucleotide binding protein  stimulatory guanine nucleotide binding protein  glucagon receptor  inhibitory guanine nucleotide binding protein  protein binding  stimulatory guanine nucleotide binding protein  chemical binding  enzyme activity  gene expression  mutagenicity  protein  alpha helix  Article  binding affinity  carboxy terminal sequence  conformational transition  cryoelectron microscopy  human  molecular recognition  mutagenesis  priority journal  protein binding  protein function  protein protein interaction  protein structure  signal transduction  binding site  chemistry  metabolism  molecular model  protein conformation  ultrastructure  Binding Sites  Cryoelectron Microscopy  Glucagon  GTP-Binding Protein alpha Subunits, Gi-Go  GTP-Binding Protein alpha Subunits, Gs  Humans  Models, Molecular  Protein Binding  Protein Conformation  Protein Conformation, alpha-Helical  Receptors, Glucagon  Signal Transduction  
Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Zhou Z.;  He H.;  Wang K.;  Shi X.;  Wang Y.;  Su Y.;  Wang Y.;  Li D.;  Liu W.;  Zhang Y.;  Shen L.;  Han W.;  Shen L.;  Ding J.;  Shao F.
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/28
cell  cell component  cytology  enzyme  enzyme activity  gene expression  immunity  tumor  Mus  gamma interferon  granzyme  GSDMB protein, human  GZMA protein, human  pore forming cytotoxic protein  tumor protein  animal  Bagg albino mouse  chemistry  cytotoxic T lymphocyte  enzymology  genetics  HEK293 cell line  human  immunology  metabolism  mouse  natural killer cell  neoplasm  pathology  protein degradation  protein domain  pyroptosis  transgenic mouse  Animals  Granzymes  HEK293 Cells  Humans  Interferon-gamma  Killer Cells, Natural  Mice  Mice, Inbred BALB C  Mice, Transgenic  Neoplasm Proteins  Neoplasms  Pore Forming Cytotoxic Proteins  Protein Domains  Proteolysis  Pyroptosis  T-Lymphocytes, Cytotoxic  
Kinetic pathways of ionic transport in fast-charging lithium titanate 期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:  Zhang W.;  Seo D.-H.;  Chen T.;  Wu L.;  Topsakal M.;  Zhu Y.;  Lu D.;  Ceder G.;  Wang F.
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1 butyl 1 methylpyrrolidinium bis(trifluoromethylsulfonyl) imide  electrolyte  imide  ionic liquid electrolyte  lithium  lithium bis (trifluoromethanesulfonyl)imide  lithium ion  lithium titanate  oxygen  unclassified drug  diffusion  electrode  ionic composition  lithium  reaction kinetics  titanate  transformation  two phase flow  Article  chemical bond  chemical reaction kinetics  concentration (parameter)  cyclic voltammetry  electricity  electrochemical analysis  electron energy loss spectroscopy  energy  ion transport  kinetics  neutron diffraction  nuclear magnetic resonance spectroscopy  priority journal  quantitative analysis  reduction (chemistry)  transmission electron microscopy  X ray absorption spectroscopy  
A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Wu Y.;  Wang F.;  Shen C.;  Peng W.;  Li D.;  Zhao C.;  Li Z.;  Li S.;  Bi Y.;  Yang Y.;  Gong Y.;  Xiao H.;  Fan Z.;  Tan S.;  Wu G.;  Tan W.;  Lu X.;  Fan C.;  Wang Q.;  Liu Y.;  Zhang C.;  Qi J.;  Gao G.F.;  Gao F.;  Liu L.
收藏  |  浏览/下载：29/0  |  提交时间：2020/07/28
Coronavirus  angiotensin converting enzyme 2  coronavirus spike glycoprotein  dipeptidyl carboxypeptidase  epitope  monoclonal antibody  neutralizing antibody  virus antibody  virus receptor  animal  chemistry  Coronavirus infection  disease model  human  immunology  isolation and purification  lung  mouse  pandemic  protein domain  serodiagnosis  virology  virus load  virus pneumonia  Animals  Antibodies, Monoclonal  Antibodies, Neutralizing  Antibodies, Viral  Coronavirus Infections  Disease Models, Animal  Humans  Immunodominant Epitopes  Lung  Mice  Neutralization Tests  Pandemics  Peptidyl-Dipeptidase A  Pneumonia, Viral  Protein Domains  Receptors, Virus  Spike Glycoprotein, Coronavirus  Viral Load  
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Zhang L.;  Zhao Y.;  Gao Y.;  Wu L.;  Gao R.;  Zhang Q.;  Wang Y.;  Wu C.;  Wu F.;  Gurcha S.S.;  Veerapen N.;  Batt S.M.;  Zhao W.;  Qin L.;  Yang X.;  Wang M.;  Zhu Y.;  Zhang B.;  Bi L.;  Zhang X.;  Yang H.;  Guddat L.W.;  Xu W.;  Wang Q.;  Li J.;  Besra G.S.;  Rao Z.
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/28
biochemistry  cell component  chemical binding  detection method  drug  drug resistance  enzyme  enzyme activity  inhibition  mutation  Mycobacterium tuberculosis  arabinosyltransferase  ethambutol  glycosyltransferase  tuberculostatic agent  cell wall  chemistry  cryoelectron microscopy  enzymology  multidrug resistance  Mycobacterium tuberculosis  protein conformation  Antitubercular Agents  Cell Wall  Cryoelectron Microscopy  Drug Resistance, Multiple, Bacterial  Ethambutol  Mycobacterium tuberculosis  Pentosyltransferases  Protein Conformation  
Endoplasmic reticulum-associated degradation regulates mitochondrial dynamics in brown adipocytes 期刊论文
, 2020, 卷号: 368, 期号: 6486
作者:  Zhou Z.;  Torres M.;  Sha H.;  Halbrook C.J.;  van den Bergh F.;  Reinert R.B.;  Yamada T.;  Wang S.;  Luo Y.;  Hunter A.H.;  Wang C.;  Sanderson T.H.;  Liu M.;  Taylor A.;  Sesaki H.;  Lyssiotis C.A.;  Wu J.;  Kersten S.;  Beard D.A.;  Qi L.
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/28
Hrd1 protein  membrane protein  Sel1L protein  sigma opiate receptor  sigma receptor 1  ubiquitin protein ligase E3  unclassified drug  biodegradation  cell organelle  membrane  mitochondrion  physiology  protein  turnover  animal cell  Article  brown adipocyte  cell contact  controlled study  endoplasmic reticulum  endoplasmic reticulum associated degradation  megamitochondria  mitochondrial dynamics  mitochondrion  mouse  nonhuman  priority journal  protein metabolism  protein protein interaction  thermogenesis  three-dimensional imaging  Mus