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Immunogenicity and efficacy of the COVID-19 candidate vector vaccine MVA-SARS-2-S in preclinical vaccination 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 28
作者:  Tscherne A.;  Hendrik Schwarz J.;  Rohde C.;  Kupke A.;  Kalodimou G.;  Limpinsel L.;  Okba N.M.A.;  Bošnjak B.;  Sandrock I.;  Odak I.;  Halwe S.;  Sauerhering L.;  Brosinski K.;  Liangliang N.;  Duell E.;  Jany S.;  Freudenstein A.;  Schmidt J.;  Werner A.;  Serra M.G.;  Klüver M.;  Guggemos W.;  Seilmaier M.;  Wendtner C.-M.;  Förster R.;  Haagmans B.L.;  Becker S.;  Sutter G.;  Volz A.
收藏  |  浏览/下载:40/0  |  提交时间:2021/11/25
Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 38
作者:  Dalvie N.C.;  Rodriguez-Aponte S.A.;  Hartwell B.L.;  Tostanoski L.H.;  Biedermann A.M.;  Crowell L.E.;  Kaur K.;  Kumru O.S.;  Carter L.;  Yu J.;  Chang A.;  McMahan K.;  Courant T.;  Lebas C.;  Lemnios A.A.;  Rodrigues K.A.;  Silva M.;  Johnston R.S.;  Naranjo C.A.;  Tracey M.K.;  Brady J.R.;  Whittaker C.A.;  Yun D.;  Brunette N.;  Wang J.Y.;  Walkey C.;  Fiala B.;  Kar S.;  Porto M.;  Lok M.;  Andersen H.;  Lewis M.G.;  Love K.R.;  Camp D.L.;  Silverman J.M.;  Kleanthous H.;  Joshi S.B.;  Volkin D.B.;  Dubois P.M.;  Collin N.;  King N.P.;  Barouch D.H.;  Irvine D.J.;  Love J.C.
收藏  |  浏览/下载:27/0  |  提交时间:2021/11/25
Design and proof of concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 30
作者:  Staquicini D.I.;  Tang F.H.F.;  Markosian C.;  Yao V.J.;  Staquicini F.I.;  Dodero-Rojas E.;  Contessoto V.G.;  Davis D.;  O’Brien P.;  Habib N.;  Smith T.L.;  Bruiners N.;  Sidman R.L.;  Gennaro M.L.;  Lattime E.C.;  Libutti S.K.;  Whitford P.C.;  Burley S.K.;  Onuchic J.N.;  Arap W.;  Pasqualini R.
收藏  |  浏览/下载:38/0  |  提交时间:2021/11/25
DNAM-1 regulates Foxp3 expression in regulatory T cells by interfering with TIGIT under inflammatory conditions 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 21
作者:  Sato K.;  Yamashita-Kanemaru Y.;  Abe F.;  Murata R.;  Nakamura-Shinya Y.;  Kanemaru K.;  Muratani M.;  Veillette A.;  Goto M.;  Ito M.;  Shibuya A.;  Shibuya K.
收藏  |  浏览/下载:22/0  |  提交时间:2022/02/22
Pharmacological inhibition of MDA-9/Syntenin blocks breast cancer metastasis through suppression of IL-1β 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 21
作者:  Pradhan A.K.;  Maji S.;  Bhoopathi P.;  Talukdar S.;  Mannangatti P.;  Guo C.;  Wang X.-Y.;  Cartagena L.C.;  Idowu M.;  Landry J.W.;  Sarkar D.;  Emdad L.;  Cavenee W.K.;  Das S.K.;  Fisher P.B.
收藏  |  浏览/下载:122/0  |  提交时间:2022/02/22
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody 期刊论文
Science, 2021, 卷号: 371, 期号: 6531
作者:  Garrett Rappazzo C.;  Tse L.V.;  Kaku C.I.;  Wrapp D.;  Sakharkar M.;  Huang D.;  Deveau L.M.;  Yockachonis T.J.;  Herbert A.S.;  Battles M.B.;  O’Brien C.M.;  Brown M.E.;  Geoghegan J.C.;  Belk J.;  Peng L.;  Yang L.;  Hou Y.;  Scobey T.D.;  Burton D.R.;  Nemazee D.;  Dye J.M.;  Voss J.E.;  Gunn B.M.;  McLellan J.S.;  Baric R.S.;  Gralinski L.E.;  Walker L.M.
收藏  |  浏览/下载:46/0  |  提交时间:2022/01/14
Fluorine assembly nanocluster breaks the shackles of immunosuppression to turn the cold tumor hot 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 117, 期号: 52
作者:  Li Z.;  Zhu L.;  Sun H.;  Shen Y.;  Hu D.;  Wu W.;  Wang Y.;  Qian C.;  Sun M.
收藏  |  浏览/下载:25/0  |  提交时间:2021/05/24
Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Zhou Z.;  He H.;  Wang K.;  Shi X.;  Wang Y.;  Su Y.;  Wang Y.;  Li D.;  Liu W.;  Zhang Y.;  Shen L.;  Han W.;  Shen L.;  Ding J.;  Shao F.
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/28
cell  cell component  cytology  enzyme  enzyme activity  gene expression  immunity  tumor  Mus  gamma interferon  granzyme  GSDMB protein, human  GZMA protein, human  pore forming cytotoxic protein  tumor protein  animal  Bagg albino mouse  chemistry  cytotoxic T lymphocyte  enzymology  genetics  HEK293 cell line  human  immunology  metabolism  mouse  natural killer cell  neoplasm  pathology  protein degradation  protein domain  pyroptosis  transgenic mouse  Animals  Granzymes  HEK293 Cells  Humans  Interferon-gamma  Killer Cells, Natural  Mice  Mice, Inbred BALB C  Mice, Transgenic  Neoplasm Proteins  Neoplasms  Pore Forming Cytotoxic Proteins  Protein Domains  Proteolysis  Pyroptosis  T-Lymphocytes, Cytotoxic  
Development of an inactivated vaccine candidate for SARS-CoV-2 期刊论文
, 2020, 卷号: 369, 期号: 6499
作者:  Gao Q.;  Bao L.;  Mao H.;  Wang L.;  Xu K.;  Yang M.;  Li Y.;  Zhu L.;  Wang N.;  Lv Z.;  Gao H.;  Ge X.;  Kan B.;  Hu Y.;  Liu J.;  Cai F.;  Jiang D.;  Yin Y.;  Qin C.;  Li J.;  Gong X.;  Lou X.;  Shi W.;  Wu D.;  Zhang H.;  Zhu L.;  Deng W.;  Li Y.;  Lu J.;  Li C.;  Wang X.;  Yin W.;  Zhang Y.;  Qin C.
收藏  |  浏览/下载:33/0  |  提交时间:2020/07/28
COVID-19 vaccine  immunoglobulin G  inactivated vaccine  neutralizing antibody  virus antibody  virus vaccine  animal  Bagg albino mouse  Betacoronavirus  biosynthesis  blood  Chlorocebus aethiops  Coronavirus infection  dose response  female  immunology  isolation and purification  male  mouse  pandemic  pilot study  rat  rhesus monkey  vaccine immunogenicity  Vero cell line  virology  virus load  virus pneumonia  Wistar rat  Animals  Antibodies, Neutralizing  Antibodies, Viral  Betacoronavirus  Chlorocebus aethiops  Coronavirus Infections  Dose-Response Relationship, Immunologic  Female  Immunogenicity, Vaccine  Immunoglobulin G  Macaca mulatta  Male  Mice  Mice, Inbred BALB C  Pandemics  Pilot Projects  Pneumonia, Viral  Rats  Rats, Wistar  Vaccines, Inactivated  Vero Cells  Viral Load  Viral Vaccines  
Smoldering and flaming biomass wood smoke inhibit respiratory responses in mice 期刊论文
Inhalation Toxicology, 2019, 卷号: 31, 期号: 6
作者:  Hargrove M.M.;  Kim Y.H.;  King C.;  Wood C.E.;  Gilmour M.I.;  Dye J.A.;  Gavett S.H.
收藏  |  浏览/下载:16/0  |  提交时间:2021/05/17