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文献类型
期刊论文 [24]
发表日期
2020 [24]
语种
英语 [24]
来源机构
Science [24]
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CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation
期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:
Muendlein H.I.
;
Jetton D.
;
Connolly W.M.
;
Eidell K.P.
;
Magri Z.
;
Smirnova I.
;
Poltorak A.
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/28
FLICE inhibitory protein
interleukin 1beta
lipopolysaccharide
messenger RNA
succinate dehydrogenase (ubiquinone)
Casp1 protein, mouse
caspase 8
Cflar protein, mouse
cryopyrin
FLICE inhibitory protein
IL1B protein, mouse
inflammasome
interleukin 1beta
interleukin 1beta converting enzyme
lipopolysaccharide
succinate dehydrogenase (ubiquinone)
cell
enzyme activity
inhibition
maturation
protein
animal cell
animal experiment
Article
bone marrow derived macrophage
cell death
cell protection
complex formation
controlled study
cytokine release
in vitro study
inflammation
mouse
nonhuman
priority journal
protein analysis
protein degradation
protein function
protein interaction
pyroptosis
animal
gene knockdown
genetics
immunology
macrophage
macrophage activation
metabolism
physiology
Murinae
Animals
CASP8 and FADD-Like Apoptosis Regulating Protein
Caspase 1
Caspase 8
Electron Transport Complex II
Gene Knockdown Techniques
Inflammasomes
Interleukin-1beta
Lipopolysaccharides
Macrophage Activation
Macrophages
Mice
NLR Family, Pyrin Domain-Containing 3 Protein
Pyroptosis
Structure of the RNA-dependent RNA polymerase from COVID-19 virus
期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:
Gao Y.
;
Yan L.
;
Huang Y.
;
Liu F.
;
Zhao Y.
;
Cao L.
;
Wang T.
;
Sun Q.
;
Ming Z.
;
Zhang L.
;
Ge J.
;
Zheng L.
;
Zhang Y.
;
Wang H.
;
Zhu Y.
;
Zhu C.
;
Hu T.
;
Hua T.
;
Zhang B.
;
Yang X.
;
Li J.
;
Yang H.
;
Liu Z.
;
Xu W.
;
Guddat L.W.
;
Wang Q.
;
Lou Z.
;
Rao Z.
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/07/28
comparative study
drug
electron microscopy
enzyme
enzyme activity
RNA
virus
Coronavirus
SARS coronavirus
adenosine phosphate
alanine
antivirus agent
NSP7 protein, SARS-CoV-2
NSP8 protein, SARS-CoV-2
remdesivir
RNA directed RNA polymerase
RNA-dependent RNA polymerase, coronavirus
viral protein
beta sheet
Betacoronavirus
chemistry
cryoelectron microscopy
drug design
enzyme active site
enzymology
metabolism
molecular model
protein domain
ultrastructure
Adenosine Monophosphate
Alanine
Antiviral Agents
Betacoronavirus
Catalytic Domain
Cryoelectron Microscopy
Drug Design
Models, Molecular
Protein Conformation, beta-Strand
Protein Domains
RNA Replicase
Viral Nonstructural Proteins
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Guthrie L.M.
;
Soma S.
;
Yuan S.
;
Silva A.
;
Zulkifli M.
;
Snavely T.C.
;
Greene H.F.
;
Nunez E.
;
Lynch B.
;
de Ville C.
;
Shanbhag V.
;
Lopez F.R.
;
Acharya A.
;
Petris M.J.
;
Kim B.-E.
;
Gohil V.M.
;
Sacchettini J.C.
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/28
copper
copper zinc superoxide dismutase
cytochrome c oxidase
dopamine beta monooxygenase
elesclomol
monophenol monooxygenase
protein lysine 6 oxidase
copper
cytochrome c oxidase
elesclomol
hydrazine derivative
copper
cytochrome
enzyme
enzyme activity
mitochondrion
mortality
mutation
pathology
rodent
survival
animal cell
animal experiment
animal model
animal tissue
Article
cohort analysis
controlled study
disease severity
drug mechanism
Golgi complex
H9c2(2-1) cell line
in vivo study
male
Menkes syndrome
mitochondrial dynamics
mortality rate
mouse
nerve degeneration
nonhuman
priority journal
secretory pathway
survival rate
animal
brain
cell line
degenerative disease
disease model
drug effect
genetics
knockout mouse
Menkes syndrome
metabolism
mitochondrion
pathology
rat
transport at the cellular level
Murinae
Mus
Animals
Biological Transport
Brain
Cell Line
Copper
Copper Transporter 1
Disease Models, Animal
Electron Transport Complex IV
Hydrazines
Male
Menkes Kinky Hair Syndrome
Mice
Mice, Knockout
Mitochondria
Neurodegenerative Diseases
Rats
Widespread receptor-driven modulation in peripheral olfactory coding
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Xu L.
;
Li W.
;
Voleti V.
;
Zou D.-J.
;
Hillman E.M.C.
;
Firestein S.
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/28
antagonism
cell component
detection method
odor
olfaction
protein
animal cell
animal experiment
article
excitation
high throughput analysis
male
microscopy
mouse
nonhuman
odor
olfactory epithelium
olfactory receptor neuron
animal
confocal microscopy
innervation
mutant mouse strain
olfactory mucosa
physiology
single cell analysis
acetophenone
acetophenone derivative
benzyl acetate
benzyl derivative
citral
fragrance
Acetophenones
Acyclic Monoterpenes
Animals
Benzyl Compounds
Mice
Mice, Mutant Strains
Microscopy, Confocal
Odorants
Olfactory Mucosa
Olfactory Receptor Neurons
Single-Cell Analysis
Smell
The Ccr4-Not complex monitors the translating ribosome for codon optimality
期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:
Buschauer R.
;
Matsuo Y.
;
Sugiyama T.
;
Chen Y.-H.
;
Alhusaini N.
;
Sweet T.
;
Ikeuchi K.
;
Cheng J.
;
Matsuki Y.
;
Nobuta R.
;
Gilmozzi A.
;
Berninghausen O.
;
Tesina P.
;
Becker T.
;
Coller J.
;
Inada T.
;
Beckmann R.
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/28
exonuclease
initiation factor 5A
messenger RNA
ribosome RNA
transfer RNA
ubiquitin protein ligase E3
bioassay
biomonitoring
cell component
plant and fungus structure and form
40S ribosomal subunit
adenylation
amino terminal sequence
Article
binding site
biochemical analysis
carbon catabolite repressor 4 negative on tata complex
codon
complex formation
controlled study
cryoelectron microscopy
homeostasis
molecular interaction
nonhuman
priority journal
protein conformation
ribosome
Saccharomyces cerevisiae
sequence analysis
ubiquitination
Saccharomyces cerevisiae
Metabolomics and mass spectrometry imaging reveal channeled de novo purine synthesis in cells
期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:
Pareek V.
;
Tian H.
;
Winograd N.
;
Benkovic S.J.
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/28
adenosine phosphate
guanosine phosphate
multienzyme complex
nucleotide
purine
purine
purine derivative
cell
experimental study
imaging method
mass spectrometry
metabolism
protein
Article
biochemistry
enzyme assay
gas cluster ion beam secondary ion mass spectrometry
image analysis
mass spectrometry
metabolomics
mitochondrion
molecular imaging
molecular probe
priority journal
purine synthesis
reaction analysis
single cell analysis
biosynthesis
fluorescence imaging
HeLa cell line
human
metabolism
metabolomics
procedures
secondary ion mass spectrometry
HeLa Cells
Humans
Metabolomics
Mitochondria
Multienzyme Complexes
Optical Imaging
Purines
Single-Cell Analysis
Spectrometry, Mass, Secondary Ion
Pectin homogalacturonan nanofilament expansion drives morphogenesis in plant epidermal cells
期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:
Haas K.T.
;
Wightman R.
;
Meyerowitz E.M.
;
Peaucelle A.
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/28
cellulose
glycan
hemicellulose
pectin
pectin homogalacturonan
polysaccharide
unclassified drug
biochemistry
body shape
cell
morphogenesis
physiological response
protein
shape analysis
anisotropy
Arabidopsis
Article
cell membrane
cell shape
cell wall
controlled study
cotyledon
demethylation
epidermis cell
extracellular matrix
fibril
morphogenesis
nanoimaging
nonhuman
plant cell
plant growth
priority journal
protein domain
turgor pressure
Animalia
Light-powered CO2 fixation in a chloroplast mimic with natural and synthetic parts
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Miller T.E.
;
Beneyton T.
;
Schwander T.
;
Diehl C.
;
Girault M.
;
McLean R.
;
Chotel T.
;
Claus P.
;
Cortina N.S.
;
Baret J.-C.
;
Erb T.J.
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/28
carbon dioxide
coenzyme A
crotonyl coenzyme A
ethylmalonyl coenzyme A
hydroxybutyryl coenzyme A
unclassified drug
acyl coenzyme A
carbon dioxide
ethylmalonyl-coenzyme A
carbon dioxide
carbon fixation
catalysis
catalyst
chloroplast
enzyme
enzyme activity
Article
automation
cell size
chemical analysis
chloroplast
controlled study
encapsulation
enzyme activity
enzyme mechanism
microfluidics
photoreactivity
photosynthesis
physical parameters
priority journal
biocatalysis
biomimetics
carbon cycle
chloroplast
light
metabolism
photosynthesis
radiation response
spinach
Acyl Coenzyme A
Biocatalysis
Biomimetics
Carbon Cycle
Carbon Dioxide
Chloroplasts
Light
Photosynthesis
Spinacia oleracea
The genetic architecture of the human cerebral cortex
期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:
Grasby K.L.
;
Jahanshad N.
;
Painter J.N.
;
Colodro-Conde L.
;
Bralten J.
;
Hibar D.P.
;
Lind P.A.
;
Pizzagalli F.
;
Ching C.R.K.
;
McMahon M.A.B.
;
Shatokhina N.
;
Zsembik L.C.P.
;
Thomopoulos S.I.
;
Zhu A.H.
;
Strike L.T.
;
Agartz I.
;
Alhusaini S.
;
Almeida M.A.A.
;
Alnæs D.
;
Amlien I.K.
;
Andersson M.
;
Ard T.
;
Armstrong N.J.
;
Ashley-Koch A.
;
Atkins J.R.
;
Bernard M.
;
Brouwer R.M.
;
Buimer E.E.L.
;
Bülow R.
;
Bürger C.
;
Cannon D.M.
;
Chakravarty M.
;
Chen Q.
;
Cheung J.W.
;
Couvy-Duchesne B.
;
Dale A.M.
;
Dalvie S.
;
de Araujo T.K.
;
de Zubicaray G.I.
;
de Zwarte S.M.C.
;
den Braber A.
;
Doan N.T.
;
Dohm K.
;
Ehrlich S.
;
Engelbrecht H.-R.
;
Erk S.
;
Fan C.C.
;
Fedko I.O.
;
Foley S.F.
;
Ford J.M.
;
Fukunaga M.
;
Garrett M.E.
;
Ge T.
;
Giddaluru S.
;
Goldman A.L.
;
Green M.J.
;
Groenewold N.A.
;
Grotegerd D.
;
Gurholt T.P.
;
Gutman B.A.
;
Hansell N.K.
;
Harris M.A.
;
Harrison M.B.
;
Haswell C.C.
;
Hauser M.
;
Herms S.
;
Heslenfeld D.J.
;
Ho N.F.
;
Hoehn D.
;
Hoffmann P.
;
Holleran L.
;
Hoogman M.
;
Hottenga J.-J.
;
Ikeda M.
;
Janowitz D.
;
Jansen I.E.
;
Jia T.
;
Jockwitz C.
;
Kanai R.
;
Karama S.
;
Kasperaviciute D.
;
Kaufmann T.
;
Kelly S.
;
Kikuchi M.
;
Klein M.
;
Knapp M.
;
Knodt A.R.
;
Krämer B.
;
Lam M.
;
Lancaster T.M.
;
Lee P.H.
;
Lett T.A.
;
Lewis L.B.
;
Lopes-Cendes I.
;
Luciano M.
;
Macciardi F.
;
Marquand A.F.
;
Mathias S.R.
;
Melzer T.R.
;
Milaneschi Y.
;
Mirza-Schreiber N.
;
Moreira J.C.V.
;
Mühleisen T.W.
;
Müller-Myhsok B.
;
Najt P.
;
Nakahara S.
;
Nho K.
;
Olde Loohuis L.M.
;
Orfanos D.P.
;
Pearson J.F.
;
Pitcher T.L.
;
Pütz B.
;
Quidé Y.
;
Ragothaman A.
;
Rashid F.M.
;
Reay W.R.
;
Redlich R.
;
Reinbold C.S.
;
Repple J.
;
Richard G.
;
Riedel B.C.
;
Risacher S.L.
;
Rocha C.S.
;
Mota N.R.
;
Salminen L.
;
Saremi A.
;
Saykin A.J.
;
Schlag F.
;
Schmaal L.
;
Schofield P.R.
;
Secolin R.
;
Shapland C.Y.
;
Shen L.
;
Shin J.
;
Shumskaya E.
;
Sønderby I.E.
;
Sprooten E.
;
Tansey K.E.
;
Teumer A.
;
Thalamuthu A.
;
Tordesillas-Gutiérrez D.
;
Turner J.A.
;
Uhlmann A.
;
Vallerga C.L.
;
van der Meer D.
;
van Donkelaar M.M.J.
;
van Eijk L.
;
van Erp T.G.M.
;
van Haren N.E.M.
;
van Rooij D.
;
van Tol M.-J.
;
Veldink J.H.
;
Verhoef E.
;
Walton E.
;
Wang M.
;
Wang Y.
;
Wardlaw J.M.
;
Wen W.
;
Westlye L.T.
;
Whelan C.D.
;
Witt S.H.
;
Wittfeld K.
;
Wolf C.
;
Wolfers T.
;
Wu J.Q.
;
Yasuda C.L.
;
Zaremba D.
;
Zhang Z.
;
Zwiers M.P.
;
Artiges E.
;
Assareh A.A.
;
Ayesa-Arriola R.
;
Belger A.
;
Brandt C.L.
;
Brown G.G.
;
Cichon S.
;
Curran J.E.
;
Davies G.E.
;
Degenhardt F.
;
Dennis M.F.
;
Dietsche B.
;
Djurovic S.
;
Doherty C.P.
;
Espiritu R.
;
Garijo D.
;
Gil Y.
;
Gowland P.A.
;
Green R.C.
;
Häusler A.N.
;
Heindel W.
;
Ho B.-C.
;
Hoffmann W.U.
;
Holsboer F.
;
Homuth G.
;
Hosten N.
;
Jack C.R.
;
Jang M.
;
Jansen A.
;
Kimbrel N.A.
;
Kolskår K.
;
Koops S.
;
Krug A.
;
Lim K.O.
;
Luykx J.J.
;
Mathalon D.H.
;
Mather K.A.
;
Mattay V.S.
;
Matthews S.
;
van Son J.M.
;
McEwen S.C.
;
Melle I.
;
Morris D.W.
;
Mueller B.A.
;
Nauck M.
;
Nordvik J.E.
;
Nöthen M.M.
;
O'Leary D.S.
;
Opel N.
;
Martinot M.-L.P.
;
Bruce Pike G.
;
Preda A.
;
Quinlan E.B.
;
Rasser P.E.
;
Ratnakar V.
;
Reppermund S.
;
Steen V.M.
;
Tooney P.A.
;
Torres F.R.
;
Veltman D.J.
;
Voyvodic J.T.
;
Whelan R.
;
White T.
;
Yamamori H.
;
Adams H.H.H.
;
Bis J.C.
;
Debette S.
;
Decarli C.
;
Fornage M.
;
Gudnason V.
;
Hofer E.
;
Arfan Ikram M.
;
Launer L.
;
Longstreth W.T.
;
Lopez O.L.
;
Mazoyer B.
;
Mosley T.H.
;
Roshchupkin G.V.
;
Satizabal C.L.
;
Schmidt R.
;
Seshadri S.
;
Yang Q.
;
Alvim M.K.M.
;
Ames D.
;
Anderson T.J.
;
Andreassen O.A.
;
Arias-Vasquez A.
;
Bastin M.E.
;
Baune B.T.
;
Beckham J.C.
;
Blangero J.
;
Boomsma D.I.
;
Brodaty H.
;
Brunner H.G.
;
Buckner R.L.
;
Buitelaar J.K.
;
Bustillo J.R.
;
Cahn W.
;
Cairns M.J.
;
Calhoun V.
;
Carr V.J.
;
Caseras X.
;
Caspers S.
;
Cavalleri G.L.
;
Cendes F.
;
Corvin A.
;
Crespo-Facorro B.
;
Dalrymple-Alford J.C.
;
Dannlowski U.
;
de Geus E.J.C.
;
Deary I.J.
;
Delanty N.
;
Depondt C.
;
Desrivières S.
;
Donohoe G.
;
Espeseth T.
;
Fernández G.
;
Fisher S.E.
;
Flor H.
;
Forstner A.J.
;
Francks C.
;
Franke B.
;
Glahn D.C.
;
Gollub R.L.
;
Grabe H.J.
;
Gruber O.
;
Håberg A.K.
;
Hariri A.R.
;
Hartman C.A.
;
Hashimoto R.
;
Heinz A.
;
Henskens F.A.
;
Hillegers M.H.J.
;
Hoekstra P.J.
;
Holmes A.J.
;
Elliot Hong L.
;
Hopkins W.D.
;
Hulshoff Pol H.E.
;
Jernigan T.L.
;
Jönsson E.G.
;
Kahn R.S.
;
Kennedy M.A.
;
Kircher T.T.J.
;
Kochunov P.
;
Kwok J.B.J.
;
Le Hellard S.
;
Loughland C.M.
;
Martin N.G.
;
Martinot J.-L.
;
McDonald C.
;
McMahon K.L.
;
Meyer-Lindenberg A.
;
Michie P.T.
;
Morey R.A.
;
Mowry B.
;
Nyberg L.
;
Oosterlaan J.
;
Ophoff R.A.
;
Pantelis C.
;
Paus T.
;
Pausova Z.
;
Penninx B.W.J.H.
;
Polderman T.J.C.
;
Posthuma D.
;
Rietschel M.
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Roffman J.L.
;
Rowland L.M.
;
Sachdev P.S.
;
Sämann P.G.
;
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;
Schumann G.
;
Scott R.J.
;
Sim K.
;
Sisodiya S.M.
;
Smoller J.W.
;
Sommer I.E.
;
Pourcain B.S.
;
Stein D.J.
;
Toga A.W.
;
Trollor J.N.
;
van der Wee N.J.A.
;
van't Ent D.
;
Völzke H.
;
Walter H.
;
Weber B.
;
Weinberger D.R.
;
Wright M.J.
;
Zhou J.
;
Stein J.L.
;
Thompson P.M.
;
Medland S.E.
;
Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)-Genetics working group
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浏览/下载:47/0
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提交时间:2020/07/28
brain
genetic analysis
meta-analysis
resonance
signaling
surface area
Article
bioinformatics
brain cortex
brain function
brain region
brain tissue
cortical thickness (brain)
educational status
evidence based medicine
gene control
gene locus
genetic association
genetic correlation
genetic variability
genome-wide association study
human
human genetics
priority journal
surface area
tissue structure
Wnt signaling
anatomy and histology
attention deficit disorder
brain cortex
brain mapping
cognition
genetic variation
genetics
meta analysis
nuclear magnetic resonance imaging
organ size
Parkinson disease
Attention Deficit Disorder with Hyperactivity
Brain Mapping
Cerebral Cortex
Cognition
Genetic Loci
Genetic Variation
Genome-Wide Association Study
Humans
Magnetic Resonance Imaging
Organ Size
Parkinson Disease
Self-induced spin glass state in elemental and crystalline neodymium
期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:
Kamber U.
;
Bergman A.
;
Eich A.
;
Iusan D.
;
Steinbrecher M.
;
Hauptmann N.
;
Nordström L.
;
Katsnelson M.I.
;
Wegner D.
;
Eriksson O.
;
Eriksson O.
;
Khajetoorians A.A.
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浏览/下载:23/0
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提交时间:2020/07/28
film
glass
magnetic field
neodymium
quantitative analysis
simulation