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Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat 期刊论文
, 2020, 卷号: 368, 期号: 6493
作者:  Wang H.;  Sun S.;  Ge W.;  Zhao L.;  Hou B.;  Wang K.;  Lyu Z.;  Chen L.;  Xu S.;  Guo J.;  Li M.;  Su P.;  Li X.;  Wang G.;  Bo C.;  Fang X.;  Zhuang W.;  Cheng X.;  Wu J.;  Dong L.;  Chen W.;  Li W.;  Xiao G.;  Zhao J.;  Hao Y.;  Xu Y.;  Gao Y.;  Liu W.;  Liu Y.;  Yin H.;  Li J.;  Li X.;  Zhao Y.;  Wang X.;  Ni F.;  Ma X.;  Li A.;  Xu S.S.;  Bai G.;  Nevo E.;  Gao C.;  Ohm H.;  Kong L.
收藏  |  浏览/下载：49/0  |  提交时间：2020/07/28
fungus  gene transfer  genome  germplasm  toxin  wheat  Fungi  Fusarium  Lophopyrum elongatum  Triticum aestivum  glutathione transferase  disease resistance  Epichloe  Fusarium  genetics  horizontal gene transfer  microbiology  molecular cloning  pathogenicity  plant breeding  plant disease  Poaceae  wheat  Cloning, Molecular  Disease Resistance  Epichloe  Fusarium  Gene Transfer, Horizontal  Glutathione Transferase  Plant Breeding  Plant Diseases  Poaceae  Triticum  
Na+-gated water-conducting nanochannels for boosting CO2 conversion to liquid fuels 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Li H.;  Qiu C.;  Ren S.;  Dong Q.;  Zhang S.;  Zhou F.;  Liang X.;  Wang J.;  Li S.;  Yu M.
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/28
aluminum  carbon dioxide  carbon monoxide  copper  fuel  hydrogen  methanol  nanochannel  sodium ion  water  zeolite  zinc  carbon dioxide  high temperature  hydraulic conductivity  membrane  nanocomposite  nanotechnology  separation  sodium  thermodynamics  adsorption  Article  Brunauer Emmett Teller  catalyst  chemical composition  controlled study  crystal  density functional theory  energy dispersive X ray spectroscopy  gas  hydrogenation  measurement  priority journal  scanning electron microscopy  surface area  water permeability  
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Dai W.;  Zhang B.;  Jiang X.-M.;  Su H.;  Li J.;  Zhao Y.;  Xie X.;  Jin Z.;  Peng J.;  Liu F.;  Li C.;  Li Y.;  Bai F.;  Wang H.;  Cheng X.;  Cen X.;  Hu S.;  Yang X.;  Wang J.;  Liu X.;  Xiao G.;  Jiang H.;  Rao Z.;  Zhang L.-K.;  Xu Y.;  Yang H.;  Liu H.
收藏  |  浏览/下载：36/0  |  提交时间：2020/07/28
aldehyde  antimicrobial activity  drug  enzyme activity  infectivity  inhibitor  reaction kinetics  viral disease  Coronavirus  SARS coronavirus  3C-like proteinase, Coronavirus  antivirus agent  cysteine proteinase  viral protein  animal  Betacoronavirus  chemical structure  chemistry  Chlorocebus aethiops  Coronavirus infection  dog  drug design  drug effect  enzyme active site  enzymology  female  human  male  mouse  pandemic  preclinical study  protein tertiary structure  Sprague Dawley rat  toxicity testing  Vero cell line  virus pneumonia  Animals  Antiviral Agents  Betacoronavirus  Catalytic Domain  Chlorocebus aethiops  Coronavirus Infections  Cysteine Endopeptidases  Dogs  Drug Design  Drug Evaluation, Preclinical  Female  Humans  Male  Mice  Molecular Structure  Pandemics  Pneumonia, Viral  Protein Structure, Tertiary  Rats, Sprague-Dawley  Toxicity Tests  Vero Cells  Viral Nonstructural Proteins  
Structure of the RNA-dependent RNA polymerase from COVID-19 virus 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Gao Y.;  Yan L.;  Huang Y.;  Liu F.;  Zhao Y.;  Cao L.;  Wang T.;  Sun Q.;  Ming Z.;  Zhang L.;  Ge J.;  Zheng L.;  Zhang Y.;  Wang H.;  Zhu Y.;  Zhu C.;  Hu T.;  Hua T.;  Zhang B.;  Yang X.;  Li J.;  Yang H.;  Liu Z.;  Xu W.;  Guddat L.W.;  Wang Q.;  Lou Z.;  Rao Z.
收藏  |  浏览/下载：38/0  |  提交时间：2020/07/28
comparative study  drug  electron microscopy  enzyme  enzyme activity  RNA  virus  Coronavirus  SARS coronavirus  adenosine phosphate  alanine  antivirus agent  NSP7 protein, SARS-CoV-2  NSP8 protein, SARS-CoV-2  remdesivir  RNA directed RNA polymerase  RNA-dependent RNA polymerase, coronavirus  viral protein  beta sheet  Betacoronavirus  chemistry  cryoelectron microscopy  drug design  enzyme active site  enzymology  metabolism  molecular model  protein domain  ultrastructure  Adenosine Monophosphate  Alanine  Antiviral Agents  Betacoronavirus  Catalytic Domain  Cryoelectron Microscopy  Drug Design  Models, Molecular  Protein Conformation, beta-Strand  Protein Domains  RNA Replicase  Viral Nonstructural Proteins  
Helical quantum Hall phase in graphene on SrTiO3 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:  Veyrat L.;  Déprez C.;  Coissard A.;  Li X.;  Gay F.;  Watanabe K.;  Taniguchi T.;  Han Z.;  Piot B.A.;  Sellier H.;  Sacépé B.
收藏  |  浏览/下载：27/0  |  提交时间：2020/07/28
graphene  metal oxide  strontium titanate  unclassified drug  experimental study  magnetic field  temperature effect  topology  Article  controlled study  dielectric constant  magnetic field  prediction  priority journal  quantum mechanics  temperature  
A precise polyrotaxane synthesizer 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Qiu Y.;  Song B.;  Pezzato C.;  Shen D.;  Liu W.;  Zhang L.;  Feng Y.;  Guo Q.-H.;  Cai K.;  Li W.;  Chen H.;  Nguyen M.T.;  Shi Y.;  Cheng C.;  Dean Astumian R.;  Li X.;  Fraser Stoddart J.
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/28
A high-resolution summary of Cambrian to early Triassic marine invertebrate biodiversity 期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:  Fan J.-X.;  Shen S.-Z.;  Erwin D.H.;  Sadler P.M.;  MacLeod N.;  Cheng Q.-M.;  Hou X.-D.;  Yang J.;  Wang X.-D.;  Wang Y.;  Zhang H.;  Chen X.;  Li G.-X.;  Zhang Y.-C.;  Shi Y.-K.;  Yuan D.-X.;  Chen Q.;  Zhang L.-N.;  Li C.;  Zhao Y.-Y.
收藏  |  浏览/下载：27/0  |  提交时间：2020/07/28
autocorrelation  biodiversity  Cambrian  carbon dioxide  environmental change  extinction  fossil record  invertebrate  marine environment  Triassic  Article  biodiversity  calculation  Cambrian  China  ecology  environmental change  fossil  genetic algorithm  geology  nonhuman  priority journal  standardization  taxonomy  Triassic  animal  classification  evolution  genetics  invertebrate  partial pressure  species extinction  Invertebrata  carbon dioxide  Animals  Biodiversity  Biological Evolution  Carbon Dioxide  Extinction, Biological  Fossils  Invertebrates  Partial Pressure  
An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Tian H.;  Liu Y.;  Li Y.;  Wu C.-H.;  Chen B.;  Kraemer M.U.G.;  Li B.;  Cai J.;  Xu B.;  Yang Q.;  Wang B.;  Yang P.;  Cui Y.;  Song Y.;  Zheng P.;  Wang Q.;  Bjornstad O.N.;  Yang R.;  Grenfell B.T.;  Pybus O.G.;  Dye C.
收藏  |  浏览/下载：29/0  |  提交时间：2020/07/28
data set  disease control  disease incidence  disease transmission  epidemic  public health  viral disease  Article  China  coronavirus disease 2019  disease duration  disease transmission  epidemic  health care planning  human  incidence  infection control  influenza A (H1N1)  pandemic  patient isolation  priority journal  public health  sample size  scale up  traffic and transport  Betacoronavirus  communicable disease control  Coronavirus infection  epidemic  pandemic  public health service  regression analysis  statistical model  travel  virus pneumonia  China  Hubei  Wuhan  Coronavirus  Betacoronavirus  China  Communicable Disease Control  Coronavirus Infections  Epidemics  Humans  Incidence  Models, Statistical  Pandemics  Pneumonia, Viral  Public Health Practice  Regression Analysis  Travel  
A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Wu Y.;  Wang F.;  Shen C.;  Peng W.;  Li D.;  Zhao C.;  Li Z.;  Li S.;  Bi Y.;  Yang Y.;  Gong Y.;  Xiao H.;  Fan Z.;  Tan S.;  Wu G.;  Tan W.;  Lu X.;  Fan C.;  Wang Q.;  Liu Y.;  Zhang C.;  Qi J.;  Gao G.F.;  Gao F.;  Liu L.
收藏  |  浏览/下载：29/0  |  提交时间：2020/07/28
Coronavirus  angiotensin converting enzyme 2  coronavirus spike glycoprotein  dipeptidyl carboxypeptidase  epitope  monoclonal antibody  neutralizing antibody  virus antibody  virus receptor  animal  chemistry  Coronavirus infection  disease model  human  immunology  isolation and purification  lung  mouse  pandemic  protein domain  serodiagnosis  virology  virus load  virus pneumonia  Animals  Antibodies, Monoclonal  Antibodies, Neutralizing  Antibodies, Viral  Coronavirus Infections  Disease Models, Animal  Humans  Immunodominant Epitopes  Lung  Mice  Neutralization Tests  Pandemics  Peptidyl-Dipeptidase A  Pneumonia, Viral  Protein Domains  Receptors, Virus  Spike Glycoprotein, Coronavirus  Viral Load  
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Zhang L.;  Zhao Y.;  Gao Y.;  Wu L.;  Gao R.;  Zhang Q.;  Wang Y.;  Wu C.;  Wu F.;  Gurcha S.S.;  Veerapen N.;  Batt S.M.;  Zhao W.;  Qin L.;  Yang X.;  Wang M.;  Zhu Y.;  Zhang B.;  Bi L.;  Zhang X.;  Yang H.;  Guddat L.W.;  Xu W.;  Wang Q.;  Li J.;  Besra G.S.;  Rao Z.
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/28
biochemistry  cell component  chemical binding  detection method  drug  drug resistance  enzyme  enzyme activity  inhibition  mutation  Mycobacterium tuberculosis  arabinosyltransferase  ethambutol  glycosyltransferase  tuberculostatic agent  cell wall  chemistry  cryoelectron microscopy  enzymology  multidrug resistance  Mycobacterium tuberculosis  protein conformation  Antitubercular Agents  Cell Wall  Cryoelectron Microscopy  Drug Resistance, Multiple, Bacterial  Ethambutol  Mycobacterium tuberculosis  Pentosyltransferases  Protein Conformation