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期刊论文 [19]
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2020 [19]
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英语 [19]
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Science [19]
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CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation
期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:
Muendlein H.I.
;
Jetton D.
;
Connolly W.M.
;
Eidell K.P.
;
Magri Z.
;
Smirnova I.
;
Poltorak A.
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/28
FLICE inhibitory protein
interleukin 1beta
lipopolysaccharide
messenger RNA
succinate dehydrogenase (ubiquinone)
Casp1 protein, mouse
caspase 8
Cflar protein, mouse
cryopyrin
FLICE inhibitory protein
IL1B protein, mouse
inflammasome
interleukin 1beta
interleukin 1beta converting enzyme
lipopolysaccharide
succinate dehydrogenase (ubiquinone)
cell
enzyme activity
inhibition
maturation
protein
animal cell
animal experiment
Article
bone marrow derived macrophage
cell death
cell protection
complex formation
controlled study
cytokine release
in vitro study
inflammation
mouse
nonhuman
priority journal
protein analysis
protein degradation
protein function
protein interaction
pyroptosis
animal
gene knockdown
genetics
immunology
macrophage
macrophage activation
metabolism
physiology
Murinae
Animals
CASP8 and FADD-Like Apoptosis Regulating Protein
Caspase 1
Caspase 8
Electron Transport Complex II
Gene Knockdown Techniques
Inflammasomes
Interleukin-1beta
Lipopolysaccharides
Macrophage Activation
Macrophages
Mice
NLR Family, Pyrin Domain-Containing 3 Protein
Pyroptosis
Computing cancer's weak spots
期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:
Khamsi R.
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/28
ruxolitinib
STAT3 protein
antineoplastic agent
transcription factor
algorithm
cancer
computer simulation
disease treatment
drug development
medicine
Article
cancer cell
cancer radiotherapy
enzyme inhibition
gene activity
gene expression regulation
gene interaction
gene mutation
gene repression
gene targeting
human
laboratory test
malignant neoplasm
molecular dynamics
nonhuman
oncologist
priority journal
RNA sequencing
algorithm
genetics
mutation
neoplasm
personalized medicine
procedures
systems biology
Algorithms
Antineoplastic Agents
Humans
Mutation
Neoplasms
Precision Medicine
Systems Biology
Transcription Factors
Circadian rhythms in the absence of the clock gene Bmal1
期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:
Ray S.
;
Valekunja U.K.
;
Stangherlin A.
;
Howell S.A.
;
Snijders A.P.
;
Damodaran G.
;
Reddy A.B.
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/28
phosphoproteome
proteome
transcription factor ARNTL
transcription factor Ets
transcriptome
unclassified drug
cell component
circadian rhythm
gene
gene expression
genome
molecular analysis
animal experiment
animal tissue
Article
Bmal1 gene
circadian rhythm
controlled study
gene deletion
gene expression regulation
gene function
gene knockout
genotype
knockout mouse
light dark cycle
liver
mouse
nonhuman
oscillation
oxidation reduction potential
priority journal
RNA sequence
skin fibroblast
temperature
transcription regulation
Mammalia
Mus
Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b
期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:
Weber C.
;
Zhou Y.
;
Lee J.G.
;
Looger L.L.
;
Qian G.
;
Ge C.
;
Capel B.
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/28
STAT3 protein
calcium
histone demethylase
STAT3 protein
embryonic development
gene expression
sex determination
temperature effect
turtle
animal cell
animal experiment
Article
binding site
calcium transport
cell activation
chromatin immunoprecipitation
controlled study
dimerization
Dmrt1 gene
embryo
embryo development
environmental temperature
epigenetic repression
female
gene
gene activation
gene interaction
gene targeting
genetic transcription
gonad
high temperature
immunofluorescence test
Kdm6b gene
male
nonhuman
priority journal
protein phosphorylation
real time polymerase chain reaction
sex determination
signal transduction
temperature dependence
thermoregulation
transcription regulation
upregulation
Western blotting
animal
embryology
gene expression regulation
genetics
metabolism
phosphorylation
sex determination process
temperature
turtle
Reptilia
Trachemys scripta
Trachemys scripta elegans
Animals
Calcium
Female
Gene Expression Regulation, Developmental
Jumonji Domain-Containing Histone Demethylases
Male
Phosphorylation
Sex Determination Processes
STAT3 Transcription Factor
Temperature
Transcription, Genetic
Turtles
N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription
期刊论文
, 2020, 卷号: 367, 期号: 6477
作者:
Liu J.
;
Dou X.
;
Chen C.
;
Chen C.
;
Liu C.
;
Michelle Xu M.
;
Zhao S.
;
Shen B.
;
Gao Y.
;
Han D.
;
He C.
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/28
6 n methyladenosine
chromosome associated regulatory RNA
enhancer RNA
messenger RNA
promoter associated RNA
repeat RNA
RNA
unclassified drug
cell component
chemical compound
chromosome
methylation
RNA
animal cell
Article
biodegradation
chemical modification
chromatin
controlled study
demethylation
embryo
embryonic stem cell
exosome
methylation
METTL3 gene
mouse
nonhuman
nuclear degradation
priority journal
transcription regulation
Ythdc1 gene
Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Bessman N.J.
;
Mathieu J.R.R.
;
Renassia C.
;
Zhou L.
;
Fung T.C.
;
Fernandez K.C.
;
Austin C.
;
Moeller J.B.
;
Zumerle S.
;
Louis S.
;
Vaulont S.
;
Ajami N.J.
;
Sokol H.
;
Putzel G.G.
;
Arvedson T.
;
Sockolow R.E.
;
Lakhal-Littleton S.
;
Cloonan S.M.
;
Arora M.
;
Peyssonnaux C.
;
Sonnenberg G.F.
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/28
ferroportin
hepcidin
iron
cation transport protein
Hamp protein, mouse
hepcidin
iron
metal transporting protein 1
cell
digestive system disorder
immunity
iron
microorganism
animal cell
animal experiment
animal model
animal tissue
Article
controlled study
dendritic cell
enteritis
healing
immunity
intestine flora
intestine injury
iron blood level
iron homeostasis
iron metabolism
iron sequestration
mouse
mucosal healing
mucosal immunity
nonhuman
nutritional immunity
phagocyte
priority journal
protein expression
tissue regeneration
tissue repair
animal
dendritic cell
enteropathy
fecal microbiota transplantation
gene deletion
genetics
homeostasis
intestine mucosa
metabolism
microbiology
mutant mouse strain
physiology
Mus
Animals
Cation Transport Proteins
Dendritic Cells
Fecal Microbiota Transplantation
Gastrointestinal Microbiome
Gene Deletion
Hepcidins
Homeostasis
Intestinal Diseases
Intestinal Mucosa
Iron
Mice
Mice, Mutant Strains
Phagocytes
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Lepack A.E.
;
Werner C.T.
;
Stewart A.F.
;
Fulton S.L.
;
Zhong P.
;
Farrelly L.A.
;
Smith A.C.W.
;
Ramakrishnan A.
;
Lyu Y.
;
Bastle R.M.
;
Martin J.A.
;
Mitra S.
;
O'Connor R.M.
;
Wang Z.-J.
;
Molina H.
;
Turecki G.
;
Shen L.
;
Yan Z.
;
Calipari E.S.
;
Dietz D.M.
;
Kenny P.J.
;
Maze I.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
amidase
dopamine
histone H3
histone transamidase
protein glutamine gamma glutamyltransferase 2
RNA
unclassified drug
brain
cell
chemical compound
chemical reaction
gene expression
genetic analysis
protein
action potential
amino acid substitution
amino terminal sequence
Article
cocaine dependence
controlled study
dopamine release
dopaminergic nerve cell
dopaminergic transmission
down regulation
drug seeking behavior
enzyme activity
gene expression
histone dopaminylation
histone modification
human
human tissue
hyperpolarization
in vitro study
motivation
nerve cell plasticity
nerve projection
neuropathology
nucleus accumbens
priority journal
protein expression
protein function
reward
RNA sequence
ventral tegmentum
Rattus
Translating preclinical models to humans
期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:
Brubaker D.K.
;
Lauffenburger D.A.
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/28
detection method
model
Article
bioengineering
biomedicine
cell differentiation
cell proliferation
computer model
conceptual framework
DNA sequence
drug development
epithelium cell
gene expression profiling
high throughput sequencing
human
machine learning
molecular dynamics
nonhuman
phenotype
priority journal
proteomics
RNA sequence
sex difference
signal transduction
T lymphocyte
transcription regulation
transcriptomics
translational research
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis
期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:
Ebright R.Y.
;
Lee S.
;
Wittner B.S.
;
Niederhoffer K.L.
;
Nicholson B.T.
;
Bardia A.
;
Truesdell S.
;
Wiley D.F.
;
Wesley B.
;
Li S.
;
Mai A.
;
Aceto N.
;
Vincent-Jordan N.
;
Szabolcs A.
;
Chirn B.
;
Kreuzer J.
;
Comaills V.
;
Kalinich M.
;
Haas W.
;
Ting D.T.
;
Toner M.
;
Vasudevan S.
;
Haber D.A.
;
Maheswaran S.
;
Micalizzi D.S.
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/28
CRISPR associated protein
epidermal growth factor receptor 2
Ki 67 antigen
ribosome protein
ribosome RNA
transcription factor E2F
ribosome protein
cancer
cell
gene expression
genetic engineering
protein
RNA
tumor
animal experiment
animal model
animal tissue
Article
biogenesis
bioluminescence
breast cancer
cell cycle progression
cell cycle regulation
cell proliferation
circulating tumor cell
controlled study
enzyme activation
epithelial mesenchymal transition
gene expression profiling
genetic transcription
human
human cell
lung metastasis
metastasis
microfluidics
mouse
nonhuman
overall survival
phenotype
priority journal
progression free survival
promoter region
protein expression
protein processing
protein synthesis
proteomics
RNA sequence
transcription regulation
animal
breast tumor
cancer transplantation
CRISPR Cas system
female
gene expression regulation
genetics
pathology
sequence analysis
tumor cell line
tumor embolism
Mus
Animals
Breast Neoplasms
Cell Line, Tumor
CRISPR-Cas Systems
Female
Gene Expression Regulation, Neoplastic
Humans
Mice
Neoplasm Metastasis
Neoplasm Transplantation
Neoplastic Cells, Circulating
Ribosomal Proteins
Sequence Analysis, RNA
Peptide signaling for drought-induced tomato flower drop
期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:
Reichardt S.
;
Piepho H.-P.
;
Stintzi A.
;
Schaller A.
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/28
mitogen activated protein kinase
peptide hormone
phytaspase 2
phytosulfokine
unclassified drug
abscission
aspartic acid
crop yield
drought stress
enzyme activity
flower
fruit
gene expression
hormone
peptide
abscission
Arabidopsis
Article
bioassay
cell separation
controlled study
cytokine production
down regulation
drought
environmental stress
enzyme activity
enzyme specificity
ERF4 gene
ERT10 gene
flower
hydrolysis
hydrophobicity
IAA3 gene
immunomodulation
molecular dynamics
nonhuman
peptide signaling
PK7 gene
plant development
plant genome
priority journal
productivity
protein cleavage
protein degradation
protein expression
protein function
protein processing
regulator gene
signal transduction
tomato
TPRP gene
Lycopersicon esculentum