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| Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations 期刊论文 , 2020, 卷号: 367, 期号: 6478 作者: Wilmes S.; Hafer M.; Vuorio J.; Tucker J.A.; Winkelmann H.; Löchte S.; Stanly T.A.; Pulgar Prieto K.D.; Poojari C.; Sharma V.; Richter C.P.; Kurre R.; Hubbard S.R.; Christopher Garcia K.; Moraga I.; Vattulainen I.; Hitchcock I.S.; Piehler J.
![](/themes/default/image/downing1.png) 收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28 cytokine receptor homodimer Janus kinase 2 ligand oncoprotein cancer enzyme enzyme activity membrane molecular analysis mutation protein activation analysis Article cell membrane computer model controlled study dimerization fluorescence microscopy gene mutation HeLa cell line molecular dynamics mutant oncogene priority journal protein domain protein interaction quantitative analysis signal transduction |
| Membrane-proximal F-actin restricts local membrane protrusions and directs cell migration 期刊论文 , 2020, 卷号: 368, 期号: 6496 作者: Bisaria A.; Hayer A.; Garbett D.; Cohen D.; Meyer T.
![](/themes/default/image/downing1.png) 收藏  |  浏览/下载:31/0  |  提交时间:2020/07/28 cell component concentration (composition) membrane polymerization protein actin green fluorescent protein cell membrane cell motion cell polarity cell surface chemistry genetics human metabolism umbilical vein endothelial cell Actins Cell Membrane Cell Movement Cell Polarity Cell Surface Extensions Green Fluorescent Proteins Human Umbilical Vein Endothelial Cells Humans |
| Microenvironment mapping via Dexter energy transfer on immune cells 期刊论文 , 2020, 卷号: 367, 期号: 6482 作者: Geri J.B.; Oakley J.V.; Reyes-Robles T.; Wang T.; McCarver S.J.; White C.H.; Rodriguez-Rivera F.P.; Parker D.L.; Hett E.C.; Fadeyi O.O.; Oslund R.C.; MacMillan D.W.C.
![](/themes/default/image/downing1.png) 收藏  |  浏览/下载:33/0  |  提交时间:2020/07/28 antibody conjugate carbene programmed death 1 ligand 1 methane programmed death 1 ligand 1 antibody catalysis catalyst cell component detection method enzyme enzyme activity protein antigen binding Article cell membrane energy transfer human immunocompetent cell immunological synapse lymphocyte photocatalysis priority journal protein analysis protein protein interaction tumor microenvironment catalysis chemistry energy transfer Jurkat cell line metabolism photochemistry procedures radiation response ultraviolet radiation B7-H1 Antigen Catalysis Cell Membrane Cellular Microenvironment Energy Transfer Humans Jurkat Cells Lymphocytes Methane Photochemical Processes Protein Interaction Mapping Protein Interaction Maps Ultraviolet Rays |
| PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis 期刊论文 , 2020, 卷号: 367, 期号: 6482 作者: Wang Q.; Boshoff H.I.M.; Harrison J.R.; Ray P.C.; Green S.R.; Wyatt P.G.; Barry Iii C.E.
![](/themes/default/image/downing1.png) 收藏  |  浏览/下载:21/0  |  提交时间:2020/07/28 3,3 bis di(methylsulfonyl)propionamide antiinfective agent bacterial protein glucose glycerol magnesium phosphate propionamide derivative protein proline proline glutamate protein proline proline glutamate 51 unclassified drug amide bacterial protein lipid phthiocerol dimycocerosate propionamide thiol derivative cell component chemical compound membrane mutation protein tuberculosis antibiotic resistance Article bacterial cell bacterial cell wall bacterial growth bacterial outer membrane cell division drug structure Mycobacterium tuberculosis nonhuman nutrient uptake priority journal protein depletion cell membrane cell membrane permeability chemistry drug effect gene deletion genetics metabolism transport at the cellular level Mycobacterium tuberculosis Amides Bacterial Proteins Biological Transport Cell Membrane Cell Membrane Permeability Drug Resistance, Bacterial Gene Deletion Glucose Glycerol Lipids Mycobacterium tuberculosis Sulfhydryl Compounds |
| Pectin homogalacturonan nanofilament expansion drives morphogenesis in plant epidermal cells 期刊论文 , 2020, 卷号: 367, 期号: 6481 作者: Haas K.T.; Wightman R.; Meyerowitz E.M.; Peaucelle A.
![](/themes/default/image/downing1.png) 收藏  |  浏览/下载:41/0  |  提交时间:2020/07/28 cellulose glycan hemicellulose pectin pectin homogalacturonan polysaccharide unclassified drug biochemistry body shape cell morphogenesis physiological response protein shape analysis anisotropy Arabidopsis Article cell membrane cell shape cell wall controlled study cotyledon demethylation epidermis cell extracellular matrix fibril morphogenesis nanoimaging nonhuman plant cell plant growth priority journal protein domain turgor pressure Animalia |
| Endoplasmic reticulum contact sites regulate the dynamics of membraneless organelles 期刊论文 , 2020, 卷号: 367, 期号: 6477 作者: Lee J.E.; Cathey P.I.; Wu H.; Parker R.; Voeltz G.K.
![](/themes/default/image/downing1.png) 收藏  |  浏览/下载:19/0  |  提交时间:2020/07/28 cell component cell organelle membrane protein Article biogenesis cell division cell organelle cell population cell proliferation cell structure controlled study cytoplasm dimerization endoplasmic reticulum endoplasmic reticulum stress endosome fluorescence microscopy human human cell membraneless organelle mitochondrion priority journal ribonucleoprotein granule RNA translation stress granule |
| Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division 期刊论文 , 2020, 卷号: 367, 期号: 6484 作者: Nagashima S.; Tábara L.-C.; Tilokani L.; Paupe V.; Anand H.; Pogson J.H.; Zunino R.; McBride H.M.; Prudent J.
![](/themes/default/image/downing1.png) 收藏  |  浏览/下载:27/0  |  提交时间:2020/07/28 adenosine diphosphate ribosylation factor 1 dynamin related protein 1 mitochondrial protein phosphatidylinositol 4 kinase IIIbeta phosphatidylinositol 4 phosphate phosphatidylinositol kinase unclassified drug adenosine diphosphate ribosylation factor 1 ARF1 protein, human DNM1L protein, human dynamin phosphatidylinositol 4-phosphate phosphatidylinositol kinase polyphosphoinositide cell component cell organelle chemical compound enzyme enzyme activity mitochondrion protein Article controlled study COS-7 cell line endoplasmic reticulum fibroblast gene silencing HeLa cell line human human cell membrane microdomain mitochondrial division mitochondrial dynamics mitochondrial scission priority journal protein localization trans Golgi network U2OS cell line animal cell line Chlorocebus aethiops CV-1 cell line genetics metabolism mitochondrial membrane mitochondrion RNA interference trans Golgi network ultrastructure Mammalia 1-Phosphatidylinositol 4-Kinase ADP-Ribosylation Factor 1 Animals Cell Line Chlorocebus aethiops COS Cells Dynamins Endoplasmic Reticulum HeLa Cells Humans Membrane Microdomains Mitochondria Mitochondrial Dynamics Mitochondrial Membranes Phosphatidylinositol Phosphates RNA Interference trans-Golgi Network |
| VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance 期刊论文 , 2020, 卷号: 367, 期号: 6475 作者: ElTanbouly M.A.; Zhao Y.; Nowak E.; Li J.; Schaafsma E.; Le Mercier I.; Ceeraz S.; Lines J.L.; Peng C.; Carriere C.; Huang X.; Day M.; Koehn B.; Lee S.W.; Morales M.S.; Hogquist K.A.; Jameson S.C.; Mueller D.; Rothstein J.; Blazar B.R.; Cheng C.; Noelle R.J.
![](/themes/default/image/downing1.png) 收藏  |  浏览/下载:47/0  |  提交时间:2020/07/28 cell protein interferon kruppel like factor 2 T lymphocyte receptor unclassified drug V type immunoglobulin domain containing suppressor of T cell activation protein B7 antigen Dies1 protein, mouse lymphocyte antigen receptor membrane protein monoclonal antibody VSIR protein, human biological development cell gene expression heterogeneity homeostasis immune response immunity tolerance acute graft versus host disease animal cell animal experiment animal model Article CD4+ T lymphocyte cell death cell expansion cell fate cell heterogeneity cell loss cell survival controlled study female gene gene deletion homeostasis immunological tolerance in vivo study long term survival male mouse nonhuman phenotype priority journal protein expression protein function rheumatoid arthritis RNA sequencing systemic lupus erythematosus T lymphocyte T lymphocyte activation T lymphocyte subpopulation TCR gene upregulation VISTA gene animal C57BL mouse genetics immunological tolerance immunology knockout mouse lymphocyte activation physiology T lymphocyte Mus Animals Antibodies, Monoclonal B7 Antigens Lymphocyte Activation Membrane Proteins Mice Mice, Inbred C57BL Mice, Knockout Peripheral Tolerance Receptors, Antigen, T-Cell T-Lymphocytes |
| Endoplasmic reticulum-associated degradation regulates mitochondrial dynamics in brown adipocytes 期刊论文 , 2020, 卷号: 368, 期号: 6486 作者: Zhou Z.; Torres M.; Sha H.; Halbrook C.J.; van den Bergh F.; Reinert R.B.; Yamada T.; Wang S.; Luo Y.; Hunter A.H.; Wang C.; Sanderson T.H.; Liu M.; Taylor A.; Sesaki H.; Lyssiotis C.A.; Wu J.; Kersten S.; Beard D.A.; Qi L.
![](/themes/default/image/downing1.png) 收藏  |  浏览/下载:34/0  |  提交时间:2020/07/28 Hrd1 protein membrane protein Sel1L protein sigma opiate receptor sigma receptor 1 ubiquitin protein ligase E3 unclassified drug biodegradation cell organelle membrane mitochondrion physiology protein turnover animal cell Article brown adipocyte cell contact controlled study endoplasmic reticulum endoplasmic reticulum associated degradation megamitochondria mitochondrial dynamics mitochondrion mouse nonhuman priority journal protein metabolism protein protein interaction thermogenesis three-dimensional imaging Mus |
| Liquid droplets in the skin 期刊论文 , 2020, 卷号: 367, 期号: 6483 作者: Rai A.; Pelkmans L.
![](/themes/default/image/downing1.png) 收藏  |  浏览/下载:22/0  |  提交时间:2020/07/28 keratin keratohyalin profilaggrin filaggrin keratohyalin polyadenylic acid binding protein droplet membrane physiological response separation skin cell component cell organelle physiology protein acidification Article cell culture cell differentiation cell protection cell structure epidermis human keratinocyte nonhuman permeability barrier pH phase separation priority journal protein aggregation protein expression protein phosphorylation protein processing skin cell skin permeability stoichiometry stratum corneum tissue differentiation liquid crystal skin surface property calcium cell level cell compartmentalization degenerative disease environmental stress epidermis cell ichthyosis vulgaris iquid liquid phase separation keratinocyte macromolecular crowding protein cross linking protein degradation Short Survey signal transduction Liquid Crystals Skin Surface Properties |