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Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat
期刊论文
, 2020, 卷号: 368, 期号: 6493
作者:
Wang H.
;
Sun S.
;
Ge W.
;
Zhao L.
;
Hou B.
;
Wang K.
;
Lyu Z.
;
Chen L.
;
Xu S.
;
Guo J.
;
Li M.
;
Su P.
;
Li X.
;
Wang G.
;
Bo C.
;
Fang X.
;
Zhuang W.
;
Cheng X.
;
Wu J.
;
Dong L.
;
Chen W.
;
Li W.
;
Xiao G.
;
Zhao J.
;
Hao Y.
;
Xu Y.
;
Gao Y.
;
Liu W.
;
Liu Y.
;
Yin H.
;
Li J.
;
Li X.
;
Zhao Y.
;
Wang X.
;
Ni F.
;
Ma X.
;
Li A.
;
Xu S.S.
;
Bai G.
;
Nevo E.
;
Gao C.
;
Ohm H.
;
Kong L.
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/07/28
fungus
gene transfer
genome
germplasm
toxin
wheat
Fungi
Fusarium
Lophopyrum elongatum
Triticum aestivum
glutathione transferase
disease resistance
Epichloe
Fusarium
genetics
horizontal gene transfer
microbiology
molecular cloning
pathogenicity
plant breeding
plant disease
Poaceae
wheat
Cloning, Molecular
Disease Resistance
Epichloe
Fusarium
Gene Transfer, Horizontal
Glutathione Transferase
Plant Breeding
Plant Diseases
Poaceae
Triticum
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:
Dai W.
;
Zhang B.
;
Jiang X.-M.
;
Su H.
;
Li J.
;
Zhao Y.
;
Xie X.
;
Jin Z.
;
Peng J.
;
Liu F.
;
Li C.
;
Li Y.
;
Bai F.
;
Wang H.
;
Cheng X.
;
Cen X.
;
Hu S.
;
Yang X.
;
Wang J.
;
Liu X.
;
Xiao G.
;
Jiang H.
;
Rao Z.
;
Zhang L.-K.
;
Xu Y.
;
Yang H.
;
Liu H.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
aldehyde
antimicrobial activity
drug
enzyme activity
infectivity
inhibitor
reaction kinetics
viral disease
Coronavirus
SARS coronavirus
3C-like proteinase, Coronavirus
antivirus agent
cysteine proteinase
viral protein
animal
Betacoronavirus
chemical structure
chemistry
Chlorocebus aethiops
Coronavirus infection
dog
drug design
drug effect
enzyme active site
enzymology
female
human
male
mouse
pandemic
preclinical study
protein tertiary structure
Sprague Dawley rat
toxicity testing
Vero cell line
virus pneumonia
Animals
Antiviral Agents
Betacoronavirus
Catalytic Domain
Chlorocebus aethiops
Coronavirus Infections
Cysteine Endopeptidases
Dogs
Drug Design
Drug Evaluation, Preclinical
Female
Humans
Male
Mice
Molecular Structure
Pandemics
Pneumonia, Viral
Protein Structure, Tertiary
Rats, Sprague-Dawley
Toxicity Tests
Vero Cells
Viral Nonstructural Proteins
Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses
期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:
Wu N.C.
;
Thompson A.J.
;
Lee J.M.
;
Su W.
;
Arlian B.M.
;
Xie J.
;
Lerner R.A.
;
Yen H.-L.
;
Bloom J.D.
;
Wilson I.A.
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/28
genetic analysis
hematology
influenza
mutation
pathogenicity
vaccine
virus
epitope
influenza vaccine
Influenza virus hemagglutinin
neutralizing antibody
virus antibody
chemistry
genetics
human
immunological tolerance
immunology
Influenza A virus (H1N1)
Influenza A virus (H3N2)
mutation
Antibodies, Neutralizing
Antibodies, Viral
Hemagglutinin Glycoproteins, Influenza Virus
Humans
Immune Tolerance
Immunodominant Epitopes
Influenza A Virus, H1N1 Subtype
Influenza A Virus, H3N2 Subtype
Influenza Vaccines
Mutation
Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells
期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:
Zhou Z.
;
He H.
;
Wang K.
;
Shi X.
;
Wang Y.
;
Su Y.
;
Wang Y.
;
Li D.
;
Liu W.
;
Zhang Y.
;
Shen L.
;
Han W.
;
Shen L.
;
Ding J.
;
Shao F.
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/28
cell
cell component
cytology
enzyme
enzyme activity
gene expression
immunity
tumor
Mus
gamma interferon
granzyme
GSDMB protein, human
GZMA protein, human
pore forming cytotoxic protein
tumor protein
animal
Bagg albino mouse
chemistry
cytotoxic T lymphocyte
enzymology
genetics
HEK293 cell line
human
immunology
metabolism
mouse
natural killer cell
neoplasm
pathology
protein degradation
protein domain
pyroptosis
transgenic mouse
Animals
Granzymes
HEK293 Cells
Humans
Interferon-gamma
Killer Cells, Natural
Mice
Mice, Inbred BALB C
Mice, Transgenic
Neoplasm Proteins
Neoplasms
Pore Forming Cytotoxic Proteins
Protein Domains
Proteolysis
Pyroptosis
T-Lymphocytes, Cytotoxic
Structural insights into immunoglobulin M
期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:
Li Y.
;
Wang G.
;
Li N.
;
Wang Y.
;
Zhu Q.
;
Chu H.
;
Wu W.
;
Tan Y.
;
Yu F.
;
Su X.-D.
;
Gao N.
;
Xiao J.
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/28
immunoglobulin M
secretory component
antibody
immunity
molecular analysis
polymer
protein
Article
binding site
conformational transition
cryoelectron microscopy
crystal structure
human
hydrophobicity
nonhuman
oligomerization
priority journal
protein assembly
protein domain
protein function
protein interaction
protein stability
protein structure
protein transport
surface area
On-chip integrated laser-driven particle accelerator
期刊论文
, 2020, 卷号: 367, 期号: 6473
作者:
Sapra N.V.
;
Yang K.Y.
;
Vercruysse D.
;
Leedle K.J.
;
Black D.S.
;
Joel England R.
;
Su L.
;
Trivedi R.
;
Miao Y.
;
Solgaard O.
;
Byer R.L.
;
Vučković J.
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/28
acceleration
accelerometer
integrated approach
numerical model
particle size
acceleration
Article
controlled study
cost effectiveness analysis
dielectric laser accelerator
electron radiation
optics
priority journal
process model
radiation detection
Diverse functionalization of strong alkyl C–H bonds by undirected borylation
期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:
Oeschger R.
;
Su B.
;
Yu I.
;
Ehinger C.
;
Romero E.
;
He S.
;
Hartwig J.
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/28
catalyst
chemical bonding
chemical reaction
ligand
molecular analysis