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| A mirror-image protein-based information barcoding and storage technology 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 15
作者: Zheng J.-S.; Liang J.; Shi W.-W.; Li Y.; Hu H.-G.; Tian C.-L.; Liu L.
  收藏 | 浏览/下载：20/0 | 提交时间：2021/09/01
Chemical protein synthesis Information barcoding and storage Mirror-image proteins Protein sequencing Protein-of-things |
| Temporal integration of mitogen history in mother cells controls proliferation of daughter cells 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者: Min M.; Rong Y.; Tian C.; Spencer S.L.
收藏 | 浏览/下载：29/0 | 提交时间：2020/07/28
cyclin D mitogen activated protein kinase kinase mitogenic agent cell cycle G1 phase cell cycle G2 phase cell proliferation genetics human metabolism physiology protein synthesis signal transduction stem cell Cell Proliferation Cyclin D G1 Phase G2 Phase Humans Mitogen-Activated Protein Kinase Kinases Mitogens Protein Biosynthesis Signal Transduction Stem Cells |
| Transcription polymerase-catalyzed emergence of novel RNA replicons 期刊论文
, 2020, 卷号: 368, 期号: 6487
作者: Jain N.; Blauch L.R.; Szymanski M.R.; Das R.; Tang S.K.Y.; Yin Y.W.; Fire A.Z.
收藏 | 浏览/下载：38/0 | 提交时间：2020/07/28
cell component enzyme enzyme activity genetic analysis RNA article bacteriophage catalysis DNA replication origin heredity in vitro study nonhuman plant seed replicon RNA replication synthesis transcription initiation biocatalysis biosynthesis genetic transcription metabolism Animalia Hepatitis delta virus Viroids bacteriophage T7 RNA polymerase DNA directed RNA polymerase RNA viral protein Biocatalysis DNA-Directed RNA Polymerases Replicon RNA Transcription, Genetic Viral Proteins |
| Pervasive functional translation of noncanonical human open reading frames 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者: Chen J.; Brunner A.-D.; Cogan J.Z.; Nuñez J.K.; Fields A.P.; Adamson B.; Itzhak D.N.; Li J.Y.; Mann M.; Leonetti M.D.; Weissman J.S.
收藏 | 浏览/下载：30/0 | 提交时间：2020/07/28
messenger RNA peptide transcriptome CRISPR Cas system genetics human metabolism open reading frame operon protein synthesis ribosome CRISPR-Cas Systems Humans Open Reading Frames Operon Peptides Protein Biosynthesis Ribosomes RNA, Messenger Transcriptome |
| Metabolomics and mass spectrometry imaging reveal channeled de novo purine synthesis in cells 期刊论文
, 2020, 卷号: 368, 期号: 6488
作者: Pareek V.; Tian H.; Winograd N.; Benkovic S.J.
收藏 | 浏览/下载：36/0 | 提交时间：2020/07/28
adenosine phosphate guanosine phosphate multienzyme complex nucleotide purine purine purine derivative cell experimental study imaging method mass spectrometry metabolism protein Article biochemistry enzyme assay gas cluster ion beam secondary ion mass spectrometry image analysis mass spectrometry metabolomics mitochondrion molecular imaging molecular probe priority journal purine synthesis reaction analysis single cell analysis biosynthesis fluorescence imaging HeLa cell line human metabolism metabolomics procedures secondary ion mass spectrometry HeLa Cells Humans Metabolomics Mitochondria Multienzyme Complexes Optical Imaging Purines Single-Cell Analysis Spectrometry, Mass, Secondary Ion |
| Monosomes actively translate synaptic mRNAs in neuronal processes 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者: Biever A.; Glock C.; Tushev G.; Ciirdaeva E.; Dalmay T.; Langer J.D.; Schuman E.M.
收藏 | 浏览/下载：21/0 | 提交时间：2020/07/28
proteome cell cell component protein proteomics RNA adult animal cell animal tissue Article controlled study dendrite monosome mouse neuropil nonhuman priority journal protein synthesis rat ribosome RNA transcription RNA translation synapse Rodentia |
| Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者: Ebright R.Y.; Lee S.; Wittner B.S.; Niederhoffer K.L.; Nicholson B.T.; Bardia A.; Truesdell S.; Wiley D.F.; Wesley B.; Li S.; Mai A.; Aceto N.; Vincent-Jordan N.; Szabolcs A.; Chirn B.; Kreuzer J.; Comaills V.; Kalinich M.; Haas W.; Ting D.T.; Toner M.; Vasudevan S.; Haber D.A.; Maheswaran S.; Micalizzi D.S.
收藏 | 浏览/下载：55/0 | 提交时间：2020/07/28
CRISPR associated protein epidermal growth factor receptor 2 Ki 67 antigen ribosome protein ribosome RNA transcription factor E2F ribosome protein cancer cell gene expression genetic engineering protein RNA tumor animal experiment animal model animal tissue Article biogenesis bioluminescence breast cancer cell cycle progression cell cycle regulation cell proliferation circulating tumor cell controlled study enzyme activation epithelial mesenchymal transition gene expression profiling genetic transcription human human cell lung metastasis metastasis microfluidics mouse nonhuman overall survival phenotype priority journal progression free survival promoter region protein expression protein processing protein synthesis proteomics RNA sequence transcription regulation animal breast tumor cancer transplantation CRISPR Cas system female gene expression regulation genetics pathology sequence analysis tumor cell line tumor embolism Mus Animals Breast Neoplasms Cell Line, Tumor CRISPR-Cas Systems Female Gene Expression Regulation, Neoplastic Humans Mice Neoplasm Metastasis Neoplasm Transplantation Neoplastic Cells, Circulating Ribosomal Proteins Sequence Analysis, RNA |
| Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者: Wang J.; Li P.; Yu Y.; Fu Y.; Jiang H.; Lu M.; Sun Z.; Jiang S.; Lu L.; Wu M.X.
收藏 | 浏览/下载：43/0 | 提交时间：2020/07/28
2',3' cyclic guanosine monophosphate adenosine monophosphate influenza vaccine interferon nanoparticle pulmonary surfactant biomimetic nanoparticle purine nucleotide surfactant protein A surfactant protein D unclassified drug cell drug resistance immune response immunity induced response influenza nanoparticle rodent surfactant vaccine animal cell animal experiment animal model animal tissue Article CD8+ T lymphocyte cellular immunity controlled study cross protection cytokine response drug efficacy drug safety drug synthesis female human humoral immunity hydrophilicity immune response immunopathology immunosurveillance influenza innate immunity lung alveolus epithelium cell lung alveolus macrophage mouse Mustela putorius furo nanoencapsulation nonhuman priority journal Mus Mustela |
| Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者: Reisberg S.H.; Gao Y.; Walker A.S.; Helfrich E.J.N.; Clardy J.; Baran P.S.
收藏 | 浏览/下载：43/0 | 提交时间：2020/07/28
alkaloid tryptorubin A unclassified drug alkaloid connectivity molecular analysis peptide alkylation Article bioinformatics carbon nuclear magnetic resonance chemical structure chirality cyclization dehydrogenation high performance liquid chromatography hydrogen bond hydrophobicity isomerism nonhuman nuclear magnetic resonance spectroscopy oxidation priority journal protein processing proton nuclear magnetic resonance stereochemistry Streptomyces synthesis X ray crystallography |
| Synthesis of proteins by automated flow chemistry 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者: Hartrampf N.; Saebi A.; Poskus M.; Gates Z.P.; Callahan A.J.; Cowfer A.E.; Hanna S.; Antilla S.; Schissel C.K.; Quartararo A.J.; Ye X.; Mijalis A.J.; Simon M.D.; Loas A.; Liu S.; Jessen C.; Nielsen T.E.; Pentelute B.L.
收藏 | 浏览/下载：41/0 | 提交时间：2020/07/28
amino acid cell component chemistry instrumentation peptide protein purification peptide protein chemistry isolation and purification procedures protein domain protein folding solid phase synthesis synthesis Peptides Protein Domains Protein Folding Proteins Solid-Phase Synthesis Techniques |
