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Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b 期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:  Weber C.;  Zhou Y.;  Lee J.G.;  Looger L.L.;  Qian G.;  Ge C.;  Capel B.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
STAT3 protein  calcium  histone demethylase  STAT3 protein  embryonic development  gene expression  sex determination  temperature effect  turtle  animal cell  animal experiment  Article  binding site  calcium transport  cell activation  chromatin immunoprecipitation  controlled study  dimerization  Dmrt1 gene  embryo  embryo development  environmental temperature  epigenetic repression  female  gene  gene activation  gene interaction  gene targeting  genetic transcription  gonad  high temperature  immunofluorescence test  Kdm6b gene  male  nonhuman  priority journal  protein phosphorylation  real time polymerase chain reaction  sex determination  signal transduction  temperature dependence  thermoregulation  transcription regulation  upregulation  Western blotting  animal  embryology  gene expression regulation  genetics  metabolism  phosphorylation  sex determination process  temperature  turtle  Reptilia  Trachemys scripta  Trachemys scripta elegans  Animals  Calcium  Female  Gene Expression Regulation, Developmental  Jumonji Domain-Containing Histone Demethylases  Male  Phosphorylation  Sex Determination Processes  STAT3 Transcription Factor  Temperature  Transcription, Genetic  Turtles  
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking 期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:  Lepack A.E.;  Werner C.T.;  Stewart A.F.;  Fulton S.L.;  Zhong P.;  Farrelly L.A.;  Smith A.C.W.;  Ramakrishnan A.;  Lyu Y.;  Bastle R.M.;  Martin J.A.;  Mitra S.;  O'Connor R.M.;  Wang Z.-J.;  Molina H.;  Turecki G.;  Shen L.;  Yan Z.;  Calipari E.S.;  Dietz D.M.;  Kenny P.J.;  Maze I.
收藏  |  浏览/下载:49/0  |  提交时间:2020/07/28
amidase  dopamine  histone H3  histone transamidase  protein glutamine gamma glutamyltransferase 2  RNA  unclassified drug  brain  cell  chemical compound  chemical reaction  gene expression  genetic analysis  protein  action potential  amino acid substitution  amino terminal sequence  Article  cocaine dependence  controlled study  dopamine release  dopaminergic nerve cell  dopaminergic transmission  down regulation  drug seeking behavior  enzyme activity  gene expression  histone dopaminylation  histone modification  human  human tissue  hyperpolarization  in vitro study  motivation  nerve cell plasticity  nerve projection  neuropathology  nucleus accumbens  priority journal  protein expression  protein function  reward  RNA sequence  ventral tegmentum  Rattus  
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:  Ebright R.Y.;  Lee S.;  Wittner B.S.;  Niederhoffer K.L.;  Nicholson B.T.;  Bardia A.;  Truesdell S.;  Wiley D.F.;  Wesley B.;  Li S.;  Mai A.;  Aceto N.;  Vincent-Jordan N.;  Szabolcs A.;  Chirn B.;  Kreuzer J.;  Comaills V.;  Kalinich M.;  Haas W.;  Ting D.T.;  Toner M.;  Vasudevan S.;  Haber D.A.;  Maheswaran S.;  Micalizzi D.S.
收藏  |  浏览/下载:55/0  |  提交时间:2020/07/28
CRISPR associated protein  epidermal growth factor receptor 2  Ki 67 antigen  ribosome protein  ribosome RNA  transcription factor E2F  ribosome protein  cancer  cell  gene expression  genetic engineering  protein  RNA  tumor  animal experiment  animal model  animal tissue  Article  biogenesis  bioluminescence  breast cancer  cell cycle progression  cell cycle regulation  cell proliferation  circulating tumor cell  controlled study  enzyme activation  epithelial mesenchymal transition  gene expression profiling  genetic transcription  human  human cell  lung metastasis  metastasis  microfluidics  mouse  nonhuman  overall survival  phenotype  priority journal  progression free survival  promoter region  protein expression  protein processing  protein synthesis  proteomics  RNA sequence  transcription regulation  animal  breast tumor  cancer transplantation  CRISPR Cas system  female  gene expression regulation  genetics  pathology  sequence analysis  tumor cell line  tumor embolism  Mus  Animals  Breast Neoplasms  Cell Line, Tumor  CRISPR-Cas Systems  Female  Gene Expression Regulation, Neoplastic  Humans  Mice  Neoplasm Metastasis  Neoplasm Transplantation  Neoplastic Cells, Circulating  Ribosomal Proteins  Sequence Analysis, RNA  
Patterns of DNA methylation changes in elite Eucalyptus clones across contrasting environments 期刊论文
, 2020, 卷号: 474
作者:  Jacinto Pereira W.;  de Castro Rodrigues Pappas M.;  Camargo Campoe O.;  Stape J.L.;  Grattapaglia D.;  Joannis Pappas Jr G.
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/28
Alkylation  Climate change  Cloning  DNA  Environmental regulations  Forestry  Gene encoding  Association analysis  Epigenetic modification  Epigenetic regulation  Global climate changes  Multiple correspondence analysis  Phenotypic plasticity  Transposable elements  Variable environment  Methylation  adaptation  complexity  correspondence analysis  DNA  environmental response  evergreen tree  genetic variation  genome  global change  methylation  phenotypic plasticity  sampling  xylem  Alkylation  Environmental Regulations  Eucalyptus Grandis  Forestry  Methylation  Nucleic Acids  Patterns  Sites  Brazil  Eucalyptus  Eucalyptus grandis  Eucalyptus urophylla  
Vertebrate diapause preserves organisms long term through Polycomb complex members 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Hu C.-K.;  Wang W.;  Brind'Amour J.;  Singh P.P.;  Adam Reeves G.;  Lorincz M.C.;  Alvarado A.S.;  Brunet A.
收藏  |  浏览/下载:43/0  |  提交时间:2020/07/28
polycomb group protein  protein CBX7  transcriptome  unclassified drug  diapause  gene expression  metabolism  muscle  vertebrate  Article  chromatin  complex formation  developmental gene  diapause  down regulation  embryo development  fertility  gene  gene expression regulation  gene repression  genetic regulation  growth rate  lifespan  lipid metabolism  metabolism  muscle atrophy  muscle gene  neuromuscular junction  nonhuman  priority journal  protein function  tissue preservation  upregulation  vertebrate  Cyprinodontoidei  Nothobranchius furzeri  Vertebrata  
The malaria parasite has an intrinsic clock 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Rijo-Ferreira F.;  Acosta-Rodriguez V.A.;  Abel J.H.;  Kornblum I.;  Bento I.;  Kilaru G.;  Klerman E.B.;  Mota M.M.;  Takahashi J.S.
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/28
cell  circadian rhythm  food intake  malaria  Mus  Plasmodium chabaudi  transcription factor CLOCK  animal  association  circadian rhythm  darkness  eating  erythrocyte  feeding behavior  fever  gene expression regulation  genetic transcription  genetics  host parasite interaction  malaria  mouse  mutant mouse strain  parasitology  pathophysiology  physiology  Plasmodium chabaudi  Animals  Circadian Rhythm  CLOCK Proteins  Cues  Darkness  Eating  Erythrocytes  Feeding Behavior  Fever  Gene Expression Regulation  Host-Parasite Interactions  Malaria  Mice  Mice, Mutant Strains  Plasmodium chabaudi  Transcription, Genetic  
Pervasive functional translation of noncanonical human open reading frames 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Chen J.;  Brunner A.-D.;  Cogan J.Z.;  Nuñez J.K.;  Fields A.P.;  Adamson B.;  Itzhak D.N.;  Li J.Y.;  Mann M.;  Leonetti M.D.;  Weissman J.S.
收藏  |  浏览/下载:53/0  |  提交时间:2020/07/28
messenger RNA  antigen  cell component  cell organelle  chemical binding  growth  phenotype  protein  Quaternary  RNA  Article  cell function  cell growth  cellular distribution  clustered regularly interspaced short palindromic repeat  gene sequence  genetic screening  HLA system  human  non-canonical base pairing  open reading frame  operon  priority journal  protein analysis  protein binding  protein function  transcriptomics  translation regulation  Mammalia  
Next-generation epigenetic inhibitors 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Filippakopoulos P.;  Knapp S.
收藏  |  浏览/下载:21/0  |  提交时间:2020/07/28
biological marker  bromodomain inhibitor  DNA  experiment  genetic analysis  inhibitor  Article  binding site  down regulation  gene expression  histone modification  human  nonhuman  pleiotropy  priority journal  protein domain  protein folding  protein interaction  protein processing  protein targeting  transcription elongation  transcription regulation