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Pre-evaluation on stability of proposed expressway embankment with existing geothermal regulation measures in permafrost regions 期刊论文
JOURNAL OF CENTRAL SOUTH UNIVERSITY, 2021, 卷号: 28, 期号: 1
作者:  Luo, Xiao-xiao;  Ma, Qin-guo;  Jiang, Hai-qiang
收藏  |  浏览/下载:27/0  |  提交时间:2022/04/28
TEMPERATURE-CONTROLLED VENTILATION  CRUSHED-ROCK INTERLAYER  QINGHAI-TIBET HIGHWAY  COOLING PERFORMANCE  NUMERICAL-ANALYSIS  FIELD EXPERIMENT  THERMAL REGIME  FREEZE-THAW  MECHANISM  THERMOSIPHONS  
CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Muendlein H.I.;  Jetton D.;  Connolly W.M.;  Eidell K.P.;  Magri Z.;  Smirnova I.;  Poltorak A.
收藏  |  浏览/下载:49/0  |  提交时间:2020/07/28
FLICE inhibitory protein  interleukin 1beta  lipopolysaccharide  messenger RNA  succinate dehydrogenase (ubiquinone)  Casp1 protein, mouse  caspase 8  Cflar protein, mouse  cryopyrin  FLICE inhibitory protein  IL1B protein, mouse  inflammasome  interleukin 1beta  interleukin 1beta converting enzyme  lipopolysaccharide  succinate dehydrogenase (ubiquinone)  cell  enzyme activity  inhibition  maturation  protein  animal cell  animal experiment  Article  bone marrow derived macrophage  cell death  cell protection  complex formation  controlled study  cytokine release  in vitro study  inflammation  mouse  nonhuman  priority journal  protein analysis  protein degradation  protein function  protein interaction  pyroptosis  animal  gene knockdown  genetics  immunology  macrophage  macrophage activation  metabolism  physiology  Murinae  Animals  CASP8 and FADD-Like Apoptosis Regulating Protein  Caspase 1  Caspase 8  Electron Transport Complex II  Gene Knockdown Techniques  Inflammasomes  Interleukin-1beta  Lipopolysaccharides  Macrophage Activation  Macrophages  Mice  NLR Family, Pyrin Domain-Containing 3 Protein  Pyroptosis  
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Guthrie L.M.;  Soma S.;  Yuan S.;  Silva A.;  Zulkifli M.;  Snavely T.C.;  Greene H.F.;  Nunez E.;  Lynch B.;  de Ville C.;  Shanbhag V.;  Lopez F.R.;  Acharya A.;  Petris M.J.;  Kim B.-E.;  Gohil V.M.;  Sacchettini J.C.
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28
copper  copper zinc superoxide dismutase  cytochrome c oxidase  dopamine beta monooxygenase  elesclomol  monophenol monooxygenase  protein lysine 6 oxidase  copper  cytochrome c oxidase  elesclomol  hydrazine derivative  copper  cytochrome  enzyme  enzyme activity  mitochondrion  mortality  mutation  pathology  rodent  survival  animal cell  animal experiment  animal model  animal tissue  Article  cohort analysis  controlled study  disease severity  drug mechanism  Golgi complex  H9c2(2-1) cell line  in vivo study  male  Menkes syndrome  mitochondrial dynamics  mortality rate  mouse  nerve degeneration  nonhuman  priority journal  secretory pathway  survival rate  animal  brain  cell line  degenerative disease  disease model  drug effect  genetics  knockout mouse  Menkes syndrome  metabolism  mitochondrion  pathology  rat  transport at the cellular level  Murinae  Mus  Animals  Biological Transport  Brain  Cell Line  Copper  Copper Transporter 1  Disease Models, Animal  Electron Transport Complex IV  Hydrazines  Male  Menkes Kinky Hair Syndrome  Mice  Mice, Knockout  Mitochondria  Neurodegenerative Diseases  Rats  
Intravital imaging of mouse embryos 期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:  Huang Q.;  Cohen M.A.;  Alsina F.C.;  Devlin G.;  Garrett A.;  McKey J.;  Havlik P.;  Rakhilin N.;  Wang E.;  Xiang K.;  Mathews P.;  Wang L.;  Bock C.;  Ruthig V.;  Wang Y.;  Negrete M.;  Wong C.W.;  Murthy P.K.L.;  Zhang S.;  Daniel A.R.;  Kirsch D.G.;  Kang Y.;  Capel B.;  Asokan A.;  Silver D.L.;  Jaenisch R.;  Shen X.
收藏  |  浏览/下载:48/0  |  提交时间:2020/07/28
cell  embryo  embryonic development  imaging method  physiology  animal cell  animal experiment  article  autophagy (cellular)  brain cell  cell division  chimera  controlled study  diffusion  electroporation  embryo  female  microscopy  mouse  mouse embryo  neural crest cell  neurotransmission  nonhuman  placenta  retina  uterus  vascularization  viral gene delivery system  
Circadian rhythms in the absence of the clock gene Bmal1 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:  Ray S.;  Valekunja U.K.;  Stangherlin A.;  Howell S.A.;  Snijders A.P.;  Damodaran G.;  Reddy A.B.
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/28
phosphoproteome  proteome  transcription factor ARNTL  transcription factor Ets  transcriptome  unclassified drug  cell component  circadian rhythm  gene  gene expression  genome  molecular analysis  animal experiment  animal tissue  Article  Bmal1 gene  circadian rhythm  controlled study  gene deletion  gene expression regulation  gene function  gene knockout  genotype  knockout mouse  light dark cycle  liver  mouse  nonhuman  oscillation  oxidation reduction potential  priority journal  RNA sequence  skin fibroblast  temperature  transcription regulation  Mammalia  Mus  
Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b 期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:  Weber C.;  Zhou Y.;  Lee J.G.;  Looger L.L.;  Qian G.;  Ge C.;  Capel B.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
STAT3 protein  calcium  histone demethylase  STAT3 protein  embryonic development  gene expression  sex determination  temperature effect  turtle  animal cell  animal experiment  Article  binding site  calcium transport  cell activation  chromatin immunoprecipitation  controlled study  dimerization  Dmrt1 gene  embryo  embryo development  environmental temperature  epigenetic repression  female  gene  gene activation  gene interaction  gene targeting  genetic transcription  gonad  high temperature  immunofluorescence test  Kdm6b gene  male  nonhuman  priority journal  protein phosphorylation  real time polymerase chain reaction  sex determination  signal transduction  temperature dependence  thermoregulation  transcription regulation  upregulation  Western blotting  animal  embryology  gene expression regulation  genetics  metabolism  phosphorylation  sex determination process  temperature  turtle  Reptilia  Trachemys scripta  Trachemys scripta elegans  Animals  Calcium  Female  Gene Expression Regulation, Developmental  Jumonji Domain-Containing Histone Demethylases  Male  Phosphorylation  Sex Determination Processes  STAT3 Transcription Factor  Temperature  Transcription, Genetic  Turtles  
Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者:  Uckelmann H.J.;  Kim S.M.;  Wong E.M.;  Hatton C.;  Giovinazzo H.;  Gadrey J.Y.;  Krivtsov A.V.;  Rücker F.G.;  Döhner K.;  McGeehan G.M.;  Levine R.L.;  Bullinger L.;  Vassiliou G.S.;  Armstrong S.A.
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28
antileukemic agent  methionine  unclassified drug  vtp 50469  biological development  cancer  cell  disease treatment  mutation  numerical model  oral health  acute myeloid leukemia  animal cell  animal experiment  animal model  antineoplastic activity  Article  cell proliferation  cell self-renewal  chromatin  controlled study  drug targeting  gene  gene mutation  leukemia cell  molecularly targeted therapy  mouse  mouse model  nonhuman  NPM1 gene  preleukemia  priority journal  Mus  
The Adaptive Value of Numerical Competence 期刊论文
, 2020, 卷号: 35, 期号: 7
作者:  Nieder A.
收藏  |  浏览/下载:31/0  |  提交时间:2020/07/28
evolution  fitness  foraging behavior  hunting  numerical response  predation  quantitative analysis  reproductive success  social behavior  survival  Animalia  avoidance behavior  controlled study  differential threshold  foraging  human  human experiment  predation  quantitative analysis  reproduction  review  social interaction  
Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing 期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:  Bessman N.J.;  Mathieu J.R.R.;  Renassia C.;  Zhou L.;  Fung T.C.;  Fernandez K.C.;  Austin C.;  Moeller J.B.;  Zumerle S.;  Louis S.;  Vaulont S.;  Ajami N.J.;  Sokol H.;  Putzel G.G.;  Arvedson T.;  Sockolow R.E.;  Lakhal-Littleton S.;  Cloonan S.M.;  Arora M.;  Peyssonnaux C.;  Sonnenberg G.F.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
ferroportin  hepcidin  iron  cation transport protein  Hamp protein, mouse  hepcidin  iron  metal transporting protein 1  cell  digestive system disorder  immunity  iron  microorganism  animal cell  animal experiment  animal model  animal tissue  Article  controlled study  dendritic cell  enteritis  healing  immunity  intestine flora  intestine injury  iron blood level  iron homeostasis  iron metabolism  iron sequestration  mouse  mucosal healing  mucosal immunity  nonhuman  nutritional immunity  phagocyte  priority journal  protein expression  tissue regeneration  tissue repair  animal  dendritic cell  enteropathy  fecal microbiota transplantation  gene deletion  genetics  homeostasis  intestine mucosa  metabolism  microbiology  mutant mouse strain  physiology  Mus  Animals  Cation Transport Proteins  Dendritic Cells  Fecal Microbiota Transplantation  Gastrointestinal Microbiome  Gene Deletion  Hepcidins  Homeostasis  Intestinal Diseases  Intestinal Mucosa  Iron  Mice  Mice, Mutant Strains  Phagocytes  
Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice 期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:  Kimura I.;  Miyamoto J.;  Ohue-Kitano R.;  Watanabe K.;  Yamada T.;  Onuki M.;  Aoki R.;  Isobe Y.;  Kashihara D.;  Inoue D.;  Inaba A.;  Takamura Y.;  Taira S.;  Kumaki S.;  Watanabe M.;  Ito M.;  Nakagawa F.;  Irie J.;  Kakuta H.;  Shinohara M.;  Iwatsuki K.;  Tsujimoto G.;  Ohno H.;  Arita M.;  Itoh H.;  Hase K.
收藏  |  浏览/下载:45/0  |  提交时间:2020/07/28
G protein coupled receptor  G protein coupled receptor 41  G protein coupled receptor 43  glucagon like peptide 1  short chain fatty acid  unclassified drug  disease incidence  experimental study  female  microbial community  phenotype  pregnancy  rodent  adult  animal cell  animal experiment  animal model  animal tissue  Article  C57BL 6 mouse  cell differentiation  controlled study  developmental stage  diet composition  diet supplementation  dietary exposure  disease exacerbation  disease predisposition  embryo  embryo development  energy metabolism  enteroendocrine cell  female  fiber intake  germfree animal  glucose intolerance  high risk pregnancy  hyperglycemia  Institute for Cancer Research mouse  insulin metabolism  intestine flora  lipid diet  low fiber diet  male  maternal nutrition  metabolic syndrome X  mouse  newborn  nonhuman  obesity  pancreas islet beta cell  phenotype  pregnancy  prenatal development  priority journal  progeny  protein expression  risk reduction  Mus