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期刊论文 [17]
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2020 [17]
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英语 [17]
来源机构
Science [17]
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CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation
期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:
Muendlein H.I.
;
Jetton D.
;
Connolly W.M.
;
Eidell K.P.
;
Magri Z.
;
Smirnova I.
;
Poltorak A.
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/07/28
FLICE inhibitory protein
interleukin 1beta
lipopolysaccharide
messenger RNA
succinate dehydrogenase (ubiquinone)
Casp1 protein, mouse
caspase 8
Cflar protein, mouse
cryopyrin
FLICE inhibitory protein
IL1B protein, mouse
inflammasome
interleukin 1beta
interleukin 1beta converting enzyme
lipopolysaccharide
succinate dehydrogenase (ubiquinone)
cell
enzyme activity
inhibition
maturation
protein
animal cell
animal experiment
Article
bone marrow derived macrophage
cell death
cell protection
complex formation
controlled study
cytokine release
in vitro study
inflammation
mouse
nonhuman
priority journal
protein analysis
protein degradation
protein function
protein interaction
pyroptosis
animal
gene knockdown
genetics
immunology
macrophage
macrophage activation
metabolism
physiology
Murinae
Animals
CASP8 and FADD-Like Apoptosis Regulating Protein
Caspase 1
Caspase 8
Electron Transport Complex II
Gene Knockdown Techniques
Inflammasomes
Interleukin-1beta
Lipopolysaccharides
Macrophage Activation
Macrophages
Mice
NLR Family, Pyrin Domain-Containing 3 Protein
Pyroptosis
Circadian rhythms in the absence of the clock gene Bmal1
期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:
Ray S.
;
Valekunja U.K.
;
Stangherlin A.
;
Howell S.A.
;
Snijders A.P.
;
Damodaran G.
;
Reddy A.B.
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/28
phosphoproteome
proteome
transcription factor ARNTL
transcription factor Ets
transcriptome
unclassified drug
cell component
circadian rhythm
gene
gene expression
genome
molecular analysis
animal experiment
animal tissue
Article
Bmal1 gene
circadian rhythm
controlled study
gene deletion
gene expression regulation
gene function
gene knockout
genotype
knockout mouse
light dark cycle
liver
mouse
nonhuman
oscillation
oxidation reduction potential
priority journal
RNA sequence
skin fibroblast
temperature
transcription regulation
Mammalia
Mus
Liquid-liquid phase separation drives skin barrier formation
期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:
Quiroz F.G.
;
Fiore V.F.
;
Levorse J.
;
Polak L.
;
Wong E.
;
Pasolli H.A.
;
Fuchs E.
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/28
filaggrin
keratohyalin
coalescence
differentiation
separation
skin
skin disorder
stratification
amino acid composition
Article
bioengineering
biophysics
cell differentiation
cell function
cell structure
epidermis cell
genetic transfection
human
keratinocyte
liquid
live cell imaging
molecular dynamics
nonhuman
pH
phase separation
phase transition
priority journal
proteomics
sequence analysis
signal transduction
skin
skin surface
Mus
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Lepack A.E.
;
Werner C.T.
;
Stewart A.F.
;
Fulton S.L.
;
Zhong P.
;
Farrelly L.A.
;
Smith A.C.W.
;
Ramakrishnan A.
;
Lyu Y.
;
Bastle R.M.
;
Martin J.A.
;
Mitra S.
;
O'Connor R.M.
;
Wang Z.-J.
;
Molina H.
;
Turecki G.
;
Shen L.
;
Yan Z.
;
Calipari E.S.
;
Dietz D.M.
;
Kenny P.J.
;
Maze I.
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/07/28
amidase
dopamine
histone H3
histone transamidase
protein glutamine gamma glutamyltransferase 2
RNA
unclassified drug
brain
cell
chemical compound
chemical reaction
gene expression
genetic analysis
protein
action potential
amino acid substitution
amino terminal sequence
Article
cocaine dependence
controlled study
dopamine release
dopaminergic nerve cell
dopaminergic transmission
down regulation
drug seeking behavior
enzyme activity
gene expression
histone dopaminylation
histone modification
human
human tissue
hyperpolarization
in vitro study
motivation
nerve cell plasticity
nerve projection
neuropathology
nucleus accumbens
priority journal
protein expression
protein function
reward
RNA sequence
ventral tegmentum
Rattus
Marching to another clock
期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:
Brown S.A.
;
Sato M.
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/07/28
RNA
transcription factor ARNTL
transcription factor CLOCK
transcription factor Ets
brain
circadian rhythm
molecular analysis
physiological response
protein
animal cell
animal tissue
Article
binding site
cell metabolism
circadian rhythm
controlled study
feedback system
genetic transcription
molecular dynamics
mouse
nonhuman
oxidation reduction reaction
priority journal
protein analysis
protein binding
protein expression
protein function
RNA analysis
RNA transcription
RNA translation
suprachiasmatic nucleus
music
walking
Circadian Rhythm
Music
Walking
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance
期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:
ElTanbouly M.A.
;
Zhao Y.
;
Nowak E.
;
Li J.
;
Schaafsma E.
;
Le Mercier I.
;
Ceeraz S.
;
Lines J.L.
;
Peng C.
;
Carriere C.
;
Huang X.
;
Day M.
;
Koehn B.
;
Lee S.W.
;
Morales M.S.
;
Hogquist K.A.
;
Jameson S.C.
;
Mueller D.
;
Rothstein J.
;
Blazar B.R.
;
Cheng C.
;
Noelle R.J.
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2020/07/28
cell protein
interferon
kruppel like factor 2
T lymphocyte receptor
unclassified drug
V type immunoglobulin domain containing suppressor of T cell activation protein
B7 antigen
Dies1 protein, mouse
lymphocyte antigen receptor
membrane protein
monoclonal antibody
VSIR protein, human
biological development
cell
gene expression
heterogeneity
homeostasis
immune response
immunity
tolerance
acute graft versus host disease
animal cell
animal experiment
animal model
Article
CD4+ T lymphocyte
cell death
cell expansion
cell fate
cell heterogeneity
cell loss
cell survival
controlled study
female
gene
gene deletion
homeostasis
immunological tolerance
in vivo study
long term survival
male
mouse
nonhuman
phenotype
priority journal
protein expression
protein function
rheumatoid arthritis
RNA sequencing
systemic lupus erythematosus
T lymphocyte
T lymphocyte activation
T lymphocyte subpopulation
TCR gene
upregulation
VISTA gene
animal
C57BL mouse
genetics
immunological tolerance
immunology
knockout mouse
lymphocyte activation
physiology
T lymphocyte
Mus
Animals
Antibodies, Monoclonal
B7 Antigens
Lymphocyte Activation
Membrane Proteins
Mice
Mice, Inbred C57BL
Mice, Knockout
Peripheral Tolerance
Receptors, Antigen, T-Cell
T-Lymphocytes
Peptide signaling for drought-induced tomato flower drop
期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:
Reichardt S.
;
Piepho H.-P.
;
Stintzi A.
;
Schaller A.
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/28
mitogen activated protein kinase
peptide hormone
phytaspase 2
phytosulfokine
unclassified drug
abscission
aspartic acid
crop yield
drought stress
enzyme activity
flower
fruit
gene expression
hormone
peptide
abscission
Arabidopsis
Article
bioassay
cell separation
controlled study
cytokine production
down regulation
drought
environmental stress
enzyme activity
enzyme specificity
ERF4 gene
ERT10 gene
flower
hydrolysis
hydrophobicity
IAA3 gene
immunomodulation
molecular dynamics
nonhuman
peptide signaling
PK7 gene
plant development
plant genome
priority journal
productivity
protein cleavage
protein degradation
protein expression
protein function
protein processing
regulator gene
signal transduction
tomato
TPRP gene
Lycopersicon esculentum
Structure of nucleosome-bound human BAF complex
期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:
He S.
;
Wu Z.
;
Tian Y.
;
Yu Z.
;
Yu J.
;
Wang X.
;
Li J.
;
Liu B.
;
Xu Y.
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/28
actin related protein
adenosine triphosphatase
BRG1 BRM associated factor
DNA
multiprotein complex
protein SWI
retinoblastoma binding protein 2
SMARCC protein
SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily B member 1
transcription factor
transcription factor SNF
unclassified drug
cancer
enzyme activity
gene expression
hydrolysis
mutation
protein
alpha helix
Article
carboxy terminal sequence
cell interaction
cryoelectron microscopy
disease association
human
malignant neoplasm
molecular recognition
mutation
nucleosome
priority journal
protein function
protein hydrolysis
protein structure
structure analysis
Mammalia
Massively multiplex chemical transcriptomics at single-cell resolution
期刊论文
, 2020, 卷号: 367, 期号: 6473
作者:
Srivatsan S.R.
;
McFaline-Figueroa J.L.
;
Ramani V.
;
Saunders L.
;
Cao J.
;
Packer J.
;
Pliner H.A.
;
Jackson D.L.
;
Daza R.M.
;
Christiansen L.
;
Zhang F.
;
Steemers F.
;
Shendure J.
;
Trapnell C.
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/28
4 (2 aminoethylamino) 1,8 dimethylimidazo[1,2 a]quinoxaline
abexinostat
acetic acid
belinostat
cudc 101
fimepinostat
givinostat
histone deacetylase inhibitor
m 344
n [2 [3 (1 piperazinylmethyl)imidazo[2,1 b]thiazol 6 yl]phenyl] 2 quinoxalinecarboxamide
panobinostat
pracinostat
rec 2282
trametinib
transcriptome
trichostatin A
unclassified drug
transcriptome
cancer
cell
chemical analysis
detection method
experimental study
genetic analysis
resolution
A-549 cell line
animal cell
animal experiment
Article
cell function
cell heterogeneity
cell labeling
cell proliferation
chromatin
controlled study
dose response
drug activity
experimentation
gene control
genetic transcription
human
human cell
K-562 cell line
MCF-7 cell line
mouse
nonhuman
pilot study
priority journal
proof of concept
RNA sequence
screening
single cell analysis
transcriptomics
cell nucleus
drug effect
genetics
genomics
high throughput screening
metabolism
neoplasm
procedures
single cell analysis
A549 Cells
Acetates
Cell Nucleus
Chromatin
Genomics
High-Throughput Screening Assays
Histone Deacetylase Inhibitors
Humans
K562 Cells
MCF-7 Cells
Neoplasms
RNA-Seq
Single-Cell Analysis
Transcriptome
A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites
期刊论文
, 2020, 卷号: 367, 期号: 6473
作者:
Birnbaum J.
;
Scharf S.
;
Schmidt S.
;
Jonscher E.
;
Maria Hoeijmakers W.A.
;
Flemming S.
;
Toenhake C.G.
;
Schmitt M.
;
Sabitzki R.
;
Bergmann B.
;
Fröhlke U.
;
Mesén-Ramírez P.
;
Soares A.B.
;
Herrmann H.
;
Bártfai R.
;
Spielmann T.
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/28
artemisinin
artemisinin derivative
cytosol receptor
hemoglobin
protein Kelch13
protozoal protein
unclassified drug
antimalarial agent
cell
drug resistance
hemoglobin
malaria
mutation
physiology
protein
antimalarial drug resistance
Article
controlled study
endocytosis
gene inactivation
gene mutation
host cell
Kelch13 gene
nonhuman
Plasmodium
priority journal
protein analysis
protein function