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| Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者: Guthrie L.M.; Soma S.; Yuan S.; Silva A.; Zulkifli M.; Snavely T.C.; Greene H.F.; Nunez E.; Lynch B.; de Ville C.; Shanbhag V.; Lopez F.R.; Acharya A.; Petris M.J.; Kim B.-E.; Gohil V.M.; Sacchettini J.C.
  收藏 | 浏览/下载：38/0 | 提交时间：2020/07/28
copper copper zinc superoxide dismutase cytochrome c oxidase dopamine beta monooxygenase elesclomol monophenol monooxygenase protein lysine 6 oxidase copper cytochrome c oxidase elesclomol hydrazine derivative copper cytochrome enzyme enzyme activity mitochondrion mortality mutation pathology rodent survival animal cell animal experiment animal model animal tissue Article cohort analysis controlled study disease severity drug mechanism Golgi complex H9c2(2-1) cell line in vivo study male Menkes syndrome mitochondrial dynamics mortality rate mouse nerve degeneration nonhuman priority journal secretory pathway survival rate animal brain cell line degenerative disease disease model drug effect genetics knockout mouse Menkes syndrome metabolism mitochondrion pathology rat transport at the cellular level Murinae Mus Animals Biological Transport Brain Cell Line Copper Copper Transporter 1 Disease Models, Animal Electron Transport Complex IV Hydrazines Male Menkes Kinky Hair Syndrome Mice Mice, Knockout Mitochondria Neurodegenerative Diseases Rats |
| The genetic architecture of the human cerebral cortex 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者: Grasby K.L.; Jahanshad N.; Painter J.N.; Colodro-Conde L.; Bralten J.; Hibar D.P.; Lind P.A.; Pizzagalli F.; Ching C.R.K.; McMahon M.A.B.; Shatokhina N.; Zsembik L.C.P.; Thomopoulos S.I.; Zhu A.H.; Strike L.T.; Agartz I.; Alhusaini S.; Almeida M.A.A.; Alnæs D.; Amlien I.K.; Andersson M.; Ard T.; Armstrong N.J.; Ashley-Koch A.; Atkins J.R.; Bernard M.; Brouwer R.M.; Buimer E.E.L.; Bülow R.; Bürger C.; Cannon D.M.; Chakravarty M.; Chen Q.; Cheung J.W.; Couvy-Duchesne B.; Dale A.M.; Dalvie S.; de Araujo T.K.; de Zubicaray G.I.; de Zwarte S.M.C.; den Braber A.; Doan N.T.; Dohm K.; Ehrlich S.; Engelbrecht H.-R.; Erk S.; Fan C.C.; Fedko I.O.; Foley S.F.; Ford J.M.; Fukunaga M.; Garrett M.E.; Ge T.; Giddaluru S.; Goldman A.L.; Green M.J.; Groenewold N.A.; Grotegerd D.; Gurholt T.P.; Gutman B.A.; Hansell N.K.; Harris M.A.; Harrison M.B.; Haswell C.C.; Hauser M.; Herms S.; Heslenfeld D.J.; Ho N.F.; Hoehn D.; Hoffmann P.; Holleran L.; Hoogman M.; Hottenga J.-J.; Ikeda M.; Janowitz D.; Jansen I.E.; Jia T.; Jockwitz C.; Kanai R.; Karama S.; Kasperaviciute D.; Kaufmann T.; Kelly S.; Kikuchi M.; Klein M.; Knapp M.; Knodt A.R.; Krämer B.; Lam M.; Lancaster T.M.; Lee P.H.; Lett T.A.; Lewis L.B.; Lopes-Cendes I.; Luciano M.; Macciardi F.; Marquand A.F.; Mathias S.R.; Melzer T.R.; Milaneschi Y.; Mirza-Schreiber N.; Moreira J.C.V.; Mühleisen T.W.; Müller-Myhsok B.; Najt P.; Nakahara S.; Nho K.; Olde Loohuis L.M.; Orfanos D.P.; Pearson J.F.; Pitcher T.L.; Pütz B.; Quidé Y.; Ragothaman A.; Rashid F.M.; Reay W.R.; Redlich R.; Reinbold C.S.; Repple J.; Richard G.; Riedel B.C.; Risacher S.L.; Rocha C.S.; Mota N.R.; Salminen L.; Saremi A.; Saykin A.J.; Schlag F.; Schmaal L.; Schofield P.R.; Secolin R.; Shapland C.Y.; Shen L.; Shin J.; Shumskaya E.; Sønderby I.E.; Sprooten E.; Tansey K.E.; Teumer A.; Thalamuthu A.; Tordesillas-Gutiérrez D.; Turner J.A.; Uhlmann A.; Vallerga C.L.; van der Meer D.; van Donkelaar M.M.J.; van Eijk L.; van Erp T.G.M.; van Haren N.E.M.; van Rooij D.; van Tol M.-J.; Veldink J.H.; Verhoef E.; Walton E.; Wang M.; Wang Y.; Wardlaw J.M.; Wen W.; Westlye L.T.; Whelan C.D.; Witt S.H.; Wittfeld K.; Wolf C.; Wolfers T.; Wu J.Q.; Yasuda C.L.; Zaremba D.; Zhang Z.; Zwiers M.P.; Artiges E.; Assareh A.A.; Ayesa-Arriola R.; Belger A.; Brandt C.L.; Brown G.G.; Cichon S.; Curran J.E.; Davies G.E.; Degenhardt F.; Dennis M.F.; Dietsche B.; Djurovic S.; Doherty C.P.; Espiritu R.; Garijo D.; Gil Y.; Gowland P.A.; Green R.C.; Häusler A.N.; Heindel W.; Ho B.-C.; Hoffmann W.U.; Holsboer F.; Homuth G.; Hosten N.; Jack C.R.; Jang M.; Jansen A.; Kimbrel N.A.; Kolskår K.; Koops S.; Krug A.; Lim K.O.; Luykx J.J.; Mathalon D.H.; Mather K.A.; Mattay V.S.; Matthews S.; van Son J.M.; McEwen S.C.; Melle I.; Morris D.W.; Mueller B.A.; Nauck M.; Nordvik J.E.; Nöthen M.M.; O'Leary D.S.; Opel N.; Martinot M.-L.P.; Bruce Pike G.; Preda A.; Quinlan E.B.; Rasser P.E.; Ratnakar V.; Reppermund S.; Steen V.M.; Tooney P.A.; Torres F.R.; Veltman D.J.; Voyvodic J.T.; Whelan R.; White T.; Yamamori H.; Adams H.H.H.; Bis J.C.; Debette S.; Decarli C.; Fornage M.; Gudnason V.; Hofer E.; Arfan Ikram M.; Launer L.; Longstreth W.T.; Lopez O.L.; Mazoyer B.; Mosley T.H.; Roshchupkin G.V.; Satizabal C.L.; Schmidt R.; Seshadri S.; Yang Q.; Alvim M.K.M.; Ames D.; Anderson T.J.; Andreassen O.A.; Arias-Vasquez A.; Bastin M.E.; Baune B.T.; Beckham J.C.; Blangero J.; Boomsma D.I.; Brodaty H.; Brunner H.G.; Buckner R.L.; Buitelaar J.K.; Bustillo J.R.; Cahn W.; Cairns M.J.; Calhoun V.; Carr V.J.; Caseras X.; Caspers S.; Cavalleri G.L.; Cendes F.; Corvin A.; Crespo-Facorro B.; Dalrymple-Alford J.C.; Dannlowski U.; de Geus E.J.C.; Deary I.J.; Delanty N.; Depondt C.; Desrivières S.; Donohoe G.; Espeseth T.; Fernández G.; Fisher S.E.; Flor H.; Forstner A.J.; Francks C.; Franke B.; Glahn D.C.; Gollub R.L.; Grabe H.J.; Gruber O.; Håberg A.K.; Hariri A.R.; Hartman C.A.; Hashimoto R.; Heinz A.; Henskens F.A.; Hillegers M.H.J.; Hoekstra P.J.; Holmes A.J.; Elliot Hong L.; Hopkins W.D.; Hulshoff Pol H.E.; Jernigan T.L.; Jönsson E.G.; Kahn R.S.; Kennedy M.A.; Kircher T.T.J.; Kochunov P.; Kwok J.B.J.; Le Hellard S.; Loughland C.M.; Martin N.G.; Martinot J.-L.; McDonald C.; McMahon K.L.; Meyer-Lindenberg A.; Michie P.T.; Morey R.A.; Mowry B.; Nyberg L.; Oosterlaan J.; Ophoff R.A.; Pantelis C.; Paus T.; Pausova Z.; Penninx B.W.J.H.; Polderman T.J.C.; Posthuma D.; Rietschel M.; Roffman J.L.; Rowland L.M.; Sachdev P.S.; Sämann P.G.; Schall U.; Schumann G.; Scott R.J.; Sim K.; Sisodiya S.M.; Smoller J.W.; Sommer I.E.; Pourcain B.S.; Stein D.J.; Toga A.W.; Trollor J.N.; van der Wee N.J.A.; van't Ent D.; Völzke H.; Walter H.; Weber B.; Weinberger D.R.; Wright M.J.; Zhou J.; Stein J.L.; Thompson P.M.; Medland S.E.; Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)-Genetics working group
收藏 | 浏览/下载：61/0 | 提交时间：2020/07/28
brain genetic analysis meta-analysis resonance signaling surface area Article bioinformatics brain cortex brain function brain region brain tissue cortical thickness (brain) educational status evidence based medicine gene control gene locus genetic association genetic correlation genetic variability genome-wide association study human human genetics priority journal surface area tissue structure Wnt signaling anatomy and histology attention deficit disorder brain cortex brain mapping cognition genetic variation genetics meta analysis nuclear magnetic resonance imaging organ size Parkinson disease Attention Deficit Disorder with Hyperactivity Brain Mapping Cerebral Cortex Cognition Genetic Loci Genetic Variation Genome-Wide Association Study Humans Magnetic Resonance Imaging Organ Size Parkinson Disease |
| Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking 期刊论文
, 2020, 卷号: 368, 期号: 6487
作者: Lepack A.E.; Werner C.T.; Stewart A.F.; Fulton S.L.; Zhong P.; Farrelly L.A.; Smith A.C.W.; Ramakrishnan A.; Lyu Y.; Bastle R.M.; Martin J.A.; Mitra S.; O'Connor R.M.; Wang Z.-J.; Molina H.; Turecki G.; Shen L.; Yan Z.; Calipari E.S.; Dietz D.M.; Kenny P.J.; Maze I.
收藏 | 浏览/下载：51/0 | 提交时间：2020/07/28
amidase dopamine histone H3 histone transamidase protein glutamine gamma glutamyltransferase 2 RNA unclassified drug brain cell chemical compound chemical reaction gene expression genetic analysis protein action potential amino acid substitution amino terminal sequence Article cocaine dependence controlled study dopamine release dopaminergic nerve cell dopaminergic transmission down regulation drug seeking behavior enzyme activity gene expression histone dopaminylation histone modification human human tissue hyperpolarization in vitro study motivation nerve cell plasticity nerve projection neuropathology nucleus accumbens priority journal protein expression protein function reward RNA sequence ventral tegmentum Rattus |
| Marching to another clock 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者: Brown S.A.; Sato M.
收藏 | 浏览/下载：42/0 | 提交时间：2020/07/28
RNA transcription factor ARNTL transcription factor CLOCK transcription factor Ets brain circadian rhythm molecular analysis physiological response protein animal cell animal tissue Article binding site cell metabolism circadian rhythm controlled study feedback system genetic transcription molecular dynamics mouse nonhuman oxidation reduction reaction priority journal protein analysis protein binding protein expression protein function RNA analysis RNA transcription RNA translation suprachiasmatic nucleus music walking Circadian Rhythm Music Walking |
| Maintenance of neural stem cell positional identity by mixed-lineage leukemia 1 期刊论文
, 2020, 卷号: 368, 期号: 6486
作者: Delgado R.N.; Mansky B.; Ahanger S.H.; Lu C.; Andersen R.E.; Dou Y.; Alvarez-Buylla A.; Lim D.A.
收藏 | 浏览/下载：30/0 | 提交时间：2020/07/28
mixed lineage leukemia 1 protein mixed lineage leukemia protein morphogen sonic hedgehog protein unclassified drug anatomy brain cell component developmental biology inhibition adult animal cell animal experiment animal tissue Article controlled study embryo epigenetics forebrain in vivo study memory Mll1 gene mouse nerve cell nerve cell differentiation neural stem cell nonhuman priority journal Erinaceidae Murinae |
| A common hub for sleep and motor control in the substantia nigra 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者: Liu D.; Li W.; Ma C.; Zheng W.; Yao Y.; Tso C.F.; Zhong P.; Chen X.; Song J.H.; Choi W.; Paik S.-B.; Han H.; Dan Y.
收藏 | 浏览/下载：46/0 | 提交时间：2020/07/28
4 aminobutyric acid glutamate decarboxylase glutamate decarboxylase 2 parvalbumin unclassified drug brain chemical compound enzyme enzyme activity locomotion sleep animal experiment animal tissue arousal Article controlled study GABAergic system home-cage activity test locomotion motor control mouse nerve cell nerve projection nonhuman priority journal sleep substantia nigra pars reticulata wakefulness Animalia |
| An atlas of the protein-coding genes in the human, pig, and mouse brain 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者: Sjöstedt E.; Zhong W.; Fagerberg L.; Karlsson M.; Mitsios N.; Adori C.; Oksvold P.; Edfors F.; Limiszewska A.; Hikmet F.; Huang J.; Du Y.; Lin L.; Dong Z.; Yang L.; Liu X.; Jiang H.; Xu X.; Wang J.; Yang H.; Bolund L.; Mardinoglu A.; Zhang C.; von Feilitzen K.; Lindskog C.; Pontén F.; Luo Y.; Hökfelt T.; Uhlén M.; Mulder J.
收藏 | 浏览/下载：34/0 | 提交时间：2020/07/28
nerve protein transcriptome animal antibody specificity book brain C57BL mouse comparative study female gene expression regulation genetics human information processing male mouse physiology pig species difference Animals Atlases as Topic Brain Datasets as Topic Female Gene Expression Regulation Humans Male Mice Mice, Inbred C57BL Nerve Tissue Proteins Organ Specificity Species Specificity Swine Transcriptome |
| An atlas of the protein-coding genes in the human, pig, and mouse brain 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者: Sjöstedt E.; Zhong W.; Fagerberg L.; Karlsson M.; Mitsios N.; Adori C.; Oksvold P.; Edfors F.; Limiszewska A.; Hikmet F.; Huang J.; Du Y.; Lin L.; Dong Z.; Yang L.; Liu X.; Jiang H.; Xu X.; Wang J.; Yang H.; Bolund L.; Mardinoglu A.; Zhang C.; Von Feilitzen K.; Lindskog C.; Pontén F.; Luo Y.; Hökfelt T.; Uhlén M.; Mulder J.
收藏 | 浏览/下载：46/0 | 提交时间：2020/07/28
G protein coupled receptor neurotransmitter atlas brain gene gene expression pig protein Article astrocyte cerebellum gene expression level gene expression profiling gene mapping genetic code genome-wide association study genomics human hypothalamus in situ hybridization microglia nerve cell nonhuman oligodendroglia pig priority journal species comparison tissue specificity transcriptomics Mammalia Suidae |
| Cerebrospinal fluid influx drives acute ischemic tissue swelling 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者: Mestre H.; Du T.; Sweeney A.M.; Liu G.; Samson A.J.; Peng W.; Mortensen K.N.; Stæger F.F.; Bork P.A.R.; Bashford L.; Toro E.R.; Tithof J.; Kelley D.H.; Thomas J.H.; Hjorth P.G.; Martens E.A.; Mehta R.I.; Solis O.; Blinder P.; Kleinfeld D.; Hirase H.; Mori Y.; Nedergaard M.
收藏 | 浏览/下载：50/0 | 提交时间：2020/07/28
brain conceptual framework inflow stroke swelling adult animal cell animal experiment animal model animal tissue Article autopsy brain cell brain ischemia brain water cerebrospinal fluid flow controlled study glymphatic system histology human human tissue isotope labeling male mouse neuroimaging nonhuman nuclear magnetic resonance imaging perivascular space priority journal vasoconstriction Rodentia |
| Chromatin accessibility dynamics in a model of human forebrain development 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者: Trevino A.E.; Sinnott-Armstrong N.; Andersen J.; Yoon S.-J.; Huber N.; Pritchard J.K.; Chang H.Y.; Greenleaf W.J.; Pașca S.P.
收藏 | 浏览/下载：26/0 | 提交时间：2020/07/28
brain cell component developmental biology developmental stage disease genetic analysis nervous system disorder Article brain cortex brain development brain nerve cell brain tissue cell differentiation cell migration chromatin controlled study environmental factor fluorescence activated cell sorting forebrain GABAergic system glia cell heredity high throughput sequencing human human cell human tissue pluripotent stem cell priority journal RNA isolation RNA sequence RNA sequencing |
