气候变化领域集成服务门户(CCPortal): An atlas of the protein-coding genes in the human, pig, and mouse brain

CCPortal

DOI	10.1126/science.aay5947
	An atlas of the protein-coding genes in the human, pig, and mouse brain
	Sjöstedt E.; Zhong W.; Fagerberg L.; Karlsson M.; Mitsios N.; Adori C.; Oksvold P.; Edfors F.; Limiszewska A.; Hikmet F.; Huang J.; Du Y.; Lin L.; Dong Z.; Yang L.; Liu X.; Jiang H.; Xu X.; Wang J.; Yang H.; Bolund L.; Mardinoglu A.; Zhang C.; von Feilitzen K.; Lindskog C.; Pontén F.; Luo Y.; Hökfelt T.; Uhlén M.; Mulder J.
发表日期	2020
ISSN	10959203
卷号	367 期号:6482
英文摘要	The brain, with its diverse physiology and intricate cellular organization, is the most complex organ of the mammalian body. To expand our basic understanding of the neurobiology of the brain and its diseases, we performed a comprehensive molecular dissection of 10 major brain regions and multiple subregions using a variety of transcriptomics methods and antibody-based mapping. This analysis was carried out in the human, pig, and mouse brain to allow the identification of regional expression profiles, as well as to study similarities and differences in expression levels between the three species. The resulting data have been made available in an open-access Brain Atlas resource, part of the Human Protein Atlas, to allow exploration and comparison of the expression of individual protein-coding genes in various parts of the mammalian brain. Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
关键词	nerve protein transcriptome animal antibody specificity book brain C57BL mouse comparative study female gene expression regulation genetics human information processing male mouse physiology pig species difference Animals Atlases as Topic Brain Datasets as Topic Female Gene Expression Regulation Humans Male Mice Mice, Inbred C57BL Nerve Tissue Proteins Organ Specificity Species Specificity Swine Transcriptome
语种	英语
来源机构	Science (New York, N.Y.)
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/133651
推荐引用方式 GB/T 7714	Sjöstedt E.,Zhong W.,Fagerberg L.,et al. An atlas of the protein-coding genes in the human, pig, and mouse brain[J]. Science (New York, N.Y.),2020,367(6482).
APA	Sjöstedt E..,Zhong W..,Fagerberg L..,Karlsson M..,Mitsios N..,...&Mulder J..(2020).An atlas of the protein-coding genes in the human, pig, and mouse brain.,367(6482).
MLA	Sjöstedt E.,et al."An atlas of the protein-coding genes in the human, pig, and mouse brain".367.6482(2020).