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Trait dimensions in bacteria and archaea compared to vascular plants 期刊论文
Ecology Letters, 2021, 卷号: 24, 期号: 7
作者:  Westoby M.;  Gillings M.R.;  Madin J.S.;  Nielsen D.A.;  Paulsen I.T.;  Tetu S.G.
收藏  |  浏览/下载:27/0  |  提交时间:2021/09/01
archaea  bacteria  cell radial diameter  ecological strategies  genome size  maximum growth rate  plants  rRNA operon copy number  signal transduction proteins  trait ecology  
A mirror-image protein-based information barcoding and storage technology 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 15
作者:  Zheng J.-S.;  Liang J.;  Shi W.-W.;  Li Y.;  Hu H.-G.;  Tian C.-L.;  Liu L.
收藏  |  浏览/下载:20/0  |  提交时间:2021/09/01
Chemical protein synthesis  Information barcoding and storage  Mirror-image proteins  Protein sequencing  Protein-of-things  
A systematic survey of PRMT interactomes reveals the key roles of arginine methylation in the global control of RNA splicing and translation 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 13
作者:  Wei H.-H.;  Fan X.-J.;  Hu Y.;  Tian X.-X.;  Guo M.;  Mao M.-W.;  Fang Z.-Y.;  Wu P.;  Gao S.-X.;  Peng C.;  Yang Y.;  Wang Z.
收藏  |  浏览/下载:32/0  |  提交时间:2021/09/01
Alternative splicing  mRNA translation  Post-translational modification  Protein arginine methyltransferase  Ribosomal proteins  RNA-binding protein  
Deletion of phosphatidylserine flippase beta-subunit Tmem30a in satellite cells leads to delayed skeletal muscle regeneration 期刊论文
ZOOLOGICAL RESEARCH, 2021, 卷号: 42, 期号: 5
作者:  Sun, Kuan-Xiang;  Jiang, Xiao-Yan;  Li, Xiao;  Su, Yu-Jing;  Wang, Ju-Lin;  Zhang, Lin;  Yang, Ye-Ming;  Zhu, Xian-Jun
收藏  |  浏览/下载:35/0  |  提交时间:2022/04/28
PHOSPHOLIPID FLIPPASE  MUSCULAR-DYSTROPHY  CDC50 PROTEINS  STEM-CELLS  FIBROBLASTS  EXPRESSION  TRANSPORT  PROLIFERATION  LOCALIZATION  MAINTENANCE  
Genomic Signature of Shifts in Selection and Alkaline Adaptation in Highland Fish 期刊论文
GENOME BIOLOGY AND EVOLUTION, 2021, 卷号: 13, 期号: 5
作者:  Tong, Chao;  Li, Miao;  Tang, Yongtao;  Zhao, Kai
收藏  |  浏览/下载:36/0  |  提交时间:2022/04/28
ACID-BASE REGULATION  TIBETAN PLATEAU  SCHIZOTHORACINAE FISH  WIDE IDENTIFICATION  EVOLUTION  REVEALS  INSIGHTS  RESPONSES  PROTEINS  FUNDULUS  
Loss of phosphatidylserine flippase beta-subunit Tmem30a in podocytes leads to albuminuria and glomerulosclerosis 期刊论文
DISEASE MODELS & MECHANISMS, 2021, 卷号: 14, 期号: 6
作者:  Liu, Wenjing;  Peng, Lei;  Tian, Wanli;  Li, Yi;  Zhang, Ping;  Sun, Kuanxiang;  Yang, Yeming;  Li, Xiao;  Li, Guisen;  Zhu, Xianjun
收藏  |  浏览/下载:31/0  |  提交时间:2022/04/28
ENDOPLASMIC-RETICULUM STRESS  FOCAL SEGMENTAL GLOMERULOSCLEROSIS  SUBCELLULAR-LOCALIZATION  VIABLE PODOCYTES  EPITHELIAL-CELLS  MESANGIAL CELL  CDC50 PROTEINS  MOUSE MODELS  EXPRESSION  NEPHROPATHY  
The phosphatidylserine flippase beta-subunit Tmem30a is essential for normal insulin maturation and secretion 期刊论文
MOLECULAR THERAPY, 2021, 卷号: 29, 期号: 9
作者:  Yang, Yeming;  Sun, Kuanxiang;  Liu, Wenjing;  Li, Xiao;  Tian, Wanli;  Shuai, Ping;  Zhu, Xianjun
收藏  |  浏览/下载:27/0  |  提交时间:2022/04/28
PANCREATIC BETA-CELLS  FATTY LIVER-DISEASE  TRANS-GOLGI NETWORK  PHOSPHOLIPID TRANSLOCATION  ENDOPLASMIC-RETICULUM  PLASMA-MEMBRANE  CDC50 PROTEINS  OBESITY  ATPASE  GENE  
A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity 期刊论文
, 2020, 卷号: 369, 期号: 6499
作者:  Meeske A.J.;  Jia N.;  Cassel A.K.;  Kozlova A.;  Liao J.;  Wiedmann M.;  Patel D.J.;  Marraffini L.A.
收藏  |  浏览/下载:39/0  |  提交时间:2020/07/28
CRISPR associated protein  endonuclease  guide RNA  viral protein  virus RNA  bacteriophage  clustered regularly interspaced short palindromic repeat  CRISPR Cas system  DNA cleavage  genetics  Listeria  metabolism  RNA stability  virology  Bacteriophages  Clustered Regularly Interspaced Short Palindromic Repeats  CRISPR-Associated Proteins  CRISPR-Cas Systems  DNA Cleavage  Endonucleases  Listeria  RNA Stability  RNA, Guide  RNA, Viral  Viral Proteins  
Human CNS barrier-forming organoids with cerebrospinal fluid production 期刊论文
, 2020, 卷号: 369, 期号: 6500
作者:  Pellegrini L.;  Bonfio C.;  Chadwick J.;  Begum F.;  Skehel M.;  Lancaster M.A.
收藏  |  浏览/下载:39/0  |  提交时间:2020/07/28
blood brain barrier  cell culture technique  cerebrospinal fluid  choroid plexus  gene expression profiling  human  metabolism  organoid  physiology  protein cerebrospinal fluid level  proteomics  single cell analysis  Blood-Brain Barrier  Cell Culture Techniques  Cerebrospinal Fluid  Cerebrospinal Fluid Proteins  Choroid Plexus  Gene Expression Profiling  Humans  Organoids  Proteomics  Single-Cell Analysis  
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Dai W.;  Zhang B.;  Jiang X.-M.;  Su H.;  Li J.;  Zhao Y.;  Xie X.;  Jin Z.;  Peng J.;  Liu F.;  Li C.;  Li Y.;  Bai F.;  Wang H.;  Cheng X.;  Cen X.;  Hu S.;  Yang X.;  Wang J.;  Liu X.;  Xiao G.;  Jiang H.;  Rao Z.;  Zhang L.-K.;  Xu Y.;  Yang H.;  Liu H.
收藏  |  浏览/下载:45/0  |  提交时间:2020/07/28
aldehyde  antimicrobial activity  drug  enzyme activity  infectivity  inhibitor  reaction kinetics  viral disease  Coronavirus  SARS coronavirus  3C-like proteinase, Coronavirus  antivirus agent  cysteine proteinase  viral protein  animal  Betacoronavirus  chemical structure  chemistry  Chlorocebus aethiops  Coronavirus infection  dog  drug design  drug effect  enzyme active site  enzymology  female  human  male  mouse  pandemic  preclinical study  protein tertiary structure  Sprague Dawley rat  toxicity testing  Vero cell line  virus pneumonia  Animals  Antiviral Agents  Betacoronavirus  Catalytic Domain  Chlorocebus aethiops  Coronavirus Infections  Cysteine Endopeptidases  Dogs  Drug Design  Drug Evaluation, Preclinical  Female  Humans  Male  Mice  Molecular Structure  Pandemics  Pneumonia, Viral  Protein Structure, Tertiary  Rats, Sprague-Dawley  Toxicity Tests  Vero Cells  Viral Nonstructural Proteins