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Zhao Y. [3]
Gao Y. [2]
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期刊论文 [7]
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2020 [7]
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英语 [7]
来源机构
Science [7]
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Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat
期刊论文
, 2020, 卷号: 368, 期号: 6493
作者:
Wang H.
;
Sun S.
;
Ge W.
;
Zhao L.
;
Hou B.
;
Wang K.
;
Lyu Z.
;
Chen L.
;
Xu S.
;
Guo J.
;
Li M.
;
Su P.
;
Li X.
;
Wang G.
;
Bo C.
;
Fang X.
;
Zhuang W.
;
Cheng X.
;
Wu J.
;
Dong L.
;
Chen W.
;
Li W.
;
Xiao G.
;
Zhao J.
;
Hao Y.
;
Xu Y.
;
Gao Y.
;
Liu W.
;
Liu Y.
;
Yin H.
;
Li J.
;
Li X.
;
Zhao Y.
;
Wang X.
;
Ni F.
;
Ma X.
;
Li A.
;
Xu S.S.
;
Bai G.
;
Nevo E.
;
Gao C.
;
Ohm H.
;
Kong L.
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/28
fungus
gene transfer
genome
germplasm
toxin
wheat
Fungi
Fusarium
Lophopyrum elongatum
Triticum aestivum
glutathione transferase
disease resistance
Epichloe
Fusarium
genetics
horizontal gene transfer
microbiology
molecular cloning
pathogenicity
plant breeding
plant disease
Poaceae
wheat
Cloning, Molecular
Disease Resistance
Epichloe
Fusarium
Gene Transfer, Horizontal
Glutathione Transferase
Plant Breeding
Plant Diseases
Poaceae
Triticum
Structure of the RNA-dependent RNA polymerase from COVID-19 virus
期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:
Gao Y.
;
Yan L.
;
Huang Y.
;
Liu F.
;
Zhao Y.
;
Cao L.
;
Wang T.
;
Sun Q.
;
Ming Z.
;
Zhang L.
;
Ge J.
;
Zheng L.
;
Zhang Y.
;
Wang H.
;
Zhu Y.
;
Zhu C.
;
Hu T.
;
Hua T.
;
Zhang B.
;
Yang X.
;
Li J.
;
Yang H.
;
Liu Z.
;
Xu W.
;
Guddat L.W.
;
Wang Q.
;
Lou Z.
;
Rao Z.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
comparative study
drug
electron microscopy
enzyme
enzyme activity
RNA
virus
Coronavirus
SARS coronavirus
adenosine phosphate
alanine
antivirus agent
NSP7 protein, SARS-CoV-2
NSP8 protein, SARS-CoV-2
remdesivir
RNA directed RNA polymerase
RNA-dependent RNA polymerase, coronavirus
viral protein
beta sheet
Betacoronavirus
chemistry
cryoelectron microscopy
drug design
enzyme active site
enzymology
metabolism
molecular model
protein domain
ultrastructure
Adenosine Monophosphate
Alanine
Antiviral Agents
Betacoronavirus
Catalytic Domain
Cryoelectron Microscopy
Drug Design
Models, Molecular
Protein Conformation, beta-Strand
Protein Domains
RNA Replicase
Viral Nonstructural Proteins
Quantum interference in H + HD → H2 + D between direct abstraction and roaming insertion pathways
期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:
Xie Y.
;
Zhao H.
;
Wang Y.
;
Huang Y.
;
Wang T.
;
Xu X.
;
Xiao C.
;
Sun Z.
;
Zhang D.H.
;
Yang X.
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/28
chemical reaction
energetics
oscillation
probe
quantum mechanics
topology
vibration
article
oscillation
physics
Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2
期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:
Shi J.
;
Wen Z.
;
Zhong G.
;
Yang H.
;
Wang C.
;
Huang B.
;
Liu R.
;
He X.
;
Shuai L.
;
Sun Z.
;
Zhao Y.
;
Liu P.
;
Liang L.
;
Cui P.
;
Wang J.
;
Zhang X.
;
Guan Y.
;
Tan W.
;
Wu G.
;
Chen H.
;
Bu Z.
;
Bu Z.
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/28
bat
canid
disease control
disease transmission
felid
global perspective
infectious disease
poultry
severe acute respiratory syndrome
viral disease
virus
China
Hubei
Wuhan
Anas
Animalia
Canis familiaris
Coronavirus
Gallus gallus
Mustela
SARS coronavirus
Suidae
virus antibody
virus RNA
animal
Betacoronavirus
blood
cat
chicken
Coronavirus infection
disease model
disease predisposition
dog
domestic animal
duck
feces
female
immunology
isolation and purification
male
Mustela putorius furo
pandemic
physiology
pig
respiratory system
species difference
virology
virus attachment
virus pneumonia
virus replication
Animals
Animals, Domestic
Antibodies, Viral
Betacoronavirus
Cats
Chickens
Coronavirus Infections
Disease Models, Animal
Disease Susceptibility
Dogs
Ducks
Feces
Female
Ferrets
Male
Pandemics
Pneumonia, Viral
Respiratory System
RNA, Viral
Species Specificity
Sus scrofa
Virus Attachment
Virus Replication
The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak
期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:
Chinazzi M.
;
Davis J.T.
;
Ajelli M.
;
Gioannini C.
;
Litvinova M.
;
Merler S.
;
Pastore y Piontti A.
;
Mu K.
;
Rossi L.
;
Sun K.
;
Viboud C.
;
Xiong X.
;
Yu H.
;
Elizabeth Halloran M.
;
Longini I.M.
;
Jr.
;
Vespignani A.
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/28
disease severity
disease transmission
epidemic
infectivity
metapopulation
quarantine
travel behavior
viral disease
virus
Article
communicable disease control
coronavirus disease 2019
disease transmission
epidemic
human
incidence
incubation time
infection rate
population risk
prevalence
priority journal
quarantine
risk reduction
travel restriction
China
Hubei
Wuhan
Coronavirus
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved a-ketoamide inhibitors
期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:
Zhang L.
;
Lin D.
;
Sun X.
;
Curth U.
;
Drosten C.
;
Sauerhering L.
;
Becker S.
;
Rox K.
;
Hilgenfeld R.
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/28
alanine
alpha ketoamide inhibitor
antivirus agent
isoleucine
leucine
proteinase
Severe acute respiratory syndrome coronavirus 2 main protease
threonine
unclassified drug
crystal structure
drug
enzyme
enzyme activity
inhibitor
reaction kinetics
amino acid sequence
animal cell
animal experiment
animal tissue
antiviral activity
Article
catalysis
catalytic efficiency
controlled study
crystal structure
dimerization
dissociation constant
drug clearance
drug design
drug distribution
drug half life
drug potency
drug protein binding
drug solubility
drug structure
EC50
enzyme inhibition
human
human cell
hydrogen bond
hydrophobicity
IC50
maximum concentration
mean residence time
metabolic stability
mouse
nonhuman
priority journal
protein structure
RNA replication
SARS coronavirus
Severe acute respiratory syndrome coronavirus 2
viral tropism
virus inhibition
Coronavirus
SARS coronavirus
An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis
期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:
Zhao P.
;
Sun X.
;
Chaggan C.
;
Liao Z.
;
Wong K.I.
;
He F.
;
Singh S.
;
Loomba R.
;
Karin M.
;
Witztum J.L.
;
Saltiel A.R.
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/28
6,7 dihydro 4 hydroxy 3 (2' hydroxy 1,1' biphenyl 4 yl) 6 oxothieno[2,3 b]pyridine 5 carbonitrile
adenosine phosphate
caspase 3
caspase 6
caspase 7
cytochrome c
hydroxymethylglutaryl coenzyme A reductase kinase
matrix metalloproteinase
apoptosis
cytochrome
enzyme
enzyme activity
inhibition
protein
rodent
AMPK signaling
animal experiment
animal model
animal tissue
apoptosis
Article
C57BL 6 mouse
cell death
controlled study
drug mechanism
enzyme activation
enzyme activity
enzyme inhibition
enzyme phosphorylation
enzyme repression
gene knockout
human
human cell
human tissue
liver cell
liver fibrosis
liver injury
male
mouse
nonalcoholic steatohepatitis
nonhuman
priority journal
protein cleavage
protein secretion