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Transcription factor AP2 controls cnidarian germ cell induction 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:  DuBuc T.Q.;  Schnitzler C.E.;  Chrysostomou E.;  McMahon E.T.;  Febrimarsa;  Gahan J.M.;  Buggie T.;  Gornik S.G.;  Hanley S.;  Barreira S.N.;  Gonzalez P.;  Baxevanis A.D.;  Frank U.
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/28
transcription factor  transcription factor AP2  unclassified drug  clonal organism  gene expression  germ cell  invertebrate  physiological response  protein  adult  Article  cell fate  Cnidaria  embryo  female  genotype  germ cell  gonad development  Hydractinia symbiolongicarpus  male  nonhuman  phenotype  priority journal  protein expression  wild type  Animalia  Bilateria  Hydractinia symbiolongicarpus  Mammalia  
Single-cell transcriptional diversity is a hallmark of developmental potential 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者:  Gulati G.S.;  Sikandar S.S.;  Wesche D.J.;  Manjunath A.;  Bharadwaj A.;  Berger M.J.;  Ilagan F.;  Kuo A.H.;  Hsieh R.W.;  Cai S.;  Zabala M.;  Scheeren F.A.;  Lobo N.A.;  Qian D.;  Yu F.B.;  Dirbas F.M.;  Clarke M.F.;  Newman A.M.
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/28
cell  cell component  developmental biology  experimental study  genetic analysis  tumor  Article  breast cancer  breast carcinogenesis  carcinogenesis  cell differentiation  computer model  embryonic stem cell  gene expression  genetic code  genetic variability  human  in vivo study  nonhuman  phenotype  priority journal  scoring system  single cell RNA seq  upregulation  
A genetic mechanism for sexual dichromatism in birds 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Gazda M.A.;  Araújo P.M.;  Lopes R.J.;  Toomey M.B.;  Andrade P.;  Afonso S.;  Marques C.;  Nunes L.;  Pereira P.;  Trigo S.;  Hill G.E.;  Corbo J.C.;  Carneiro M.
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/28
carotenoid  color morph  enzyme activity  genetic analysis  hybrid  molecular analysis  ornamentation  phenotype  physiological response  sexual dimorphism  sexual selection  Aves  Carduelis cucullata  Fringillidae  carotenoid  dioxygenase  transcriptome  anatomy and histology  animal  evolution  female  finch  genetics  male  metabolism  physiology  pigmentation  Serinus  sex factor  sexual characteristics  Animals  Biological Evolution  Canaries  Carotenoids  Dioxygenases  Female  Finches  Male  Pigmentation  Sex Characteristics  Sex Factors  Transcriptome  
Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice 期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:  Kimura I.;  Miyamoto J.;  Ohue-Kitano R.;  Watanabe K.;  Yamada T.;  Onuki M.;  Aoki R.;  Isobe Y.;  Kashihara D.;  Inoue D.;  Inaba A.;  Takamura Y.;  Taira S.;  Kumaki S.;  Watanabe M.;  Ito M.;  Nakagawa F.;  Irie J.;  Kakuta H.;  Shinohara M.;  Iwatsuki K.;  Tsujimoto G.;  Ohno H.;  Arita M.;  Itoh H.;  Hase K.
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/28
G protein coupled receptor  G protein coupled receptor 41  G protein coupled receptor 43  glucagon like peptide 1  short chain fatty acid  unclassified drug  disease incidence  experimental study  female  microbial community  phenotype  pregnancy  rodent  adult  animal cell  animal experiment  animal model  animal tissue  Article  C57BL 6 mouse  cell differentiation  controlled study  developmental stage  diet composition  diet supplementation  dietary exposure  disease exacerbation  disease predisposition  embryo  embryo development  energy metabolism  enteroendocrine cell  female  fiber intake  germfree animal  glucose intolerance  high risk pregnancy  hyperglycemia  Institute for Cancer Research mouse  insulin metabolism  intestine flora  lipid diet  low fiber diet  male  maternal nutrition  metabolic syndrome X  mouse  newborn  nonhuman  obesity  pancreas islet beta cell  phenotype  pregnancy  prenatal development  priority journal  progeny  protein expression  risk reduction  Mus  
Translating preclinical models to humans 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:  Brubaker D.K.;  Lauffenburger D.A.
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/28
detection method  model  Article  bioengineering  biomedicine  cell differentiation  cell proliferation  computer model  conceptual framework  DNA sequence  drug development  epithelium cell  gene expression profiling  high throughput sequencing  human  machine learning  molecular dynamics  nonhuman  phenotype  priority journal  proteomics  RNA sequence  sex difference  signal transduction  T lymphocyte  transcription regulation  transcriptomics  translational research  
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance 期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:  ElTanbouly M.A.;  Zhao Y.;  Nowak E.;  Li J.;  Schaafsma E.;  Le Mercier I.;  Ceeraz S.;  Lines J.L.;  Peng C.;  Carriere C.;  Huang X.;  Day M.;  Koehn B.;  Lee S.W.;  Morales M.S.;  Hogquist K.A.;  Jameson S.C.;  Mueller D.;  Rothstein J.;  Blazar B.R.;  Cheng C.;  Noelle R.J.
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/28
cell protein  interferon  kruppel like factor 2  T lymphocyte receptor  unclassified drug  V type immunoglobulin domain containing suppressor of T cell activation protein  B7 antigen  Dies1 protein, mouse  lymphocyte antigen receptor  membrane protein  monoclonal antibody  VSIR protein, human  biological development  cell  gene expression  heterogeneity  homeostasis  immune response  immunity  tolerance  acute graft versus host disease  animal cell  animal experiment  animal model  Article  CD4+ T lymphocyte  cell death  cell expansion  cell fate  cell heterogeneity  cell loss  cell survival  controlled study  female  gene  gene deletion  homeostasis  immunological tolerance  in vivo study  long term survival  male  mouse  nonhuman  phenotype  priority journal  protein expression  protein function  rheumatoid arthritis  RNA sequencing  systemic lupus erythematosus  T lymphocyte  T lymphocyte activation  T lymphocyte subpopulation  TCR gene  upregulation  VISTA gene  animal  C57BL mouse  genetics  immunological tolerance  immunology  knockout mouse  lymphocyte activation  physiology  T lymphocyte  Mus  Animals  Antibodies, Monoclonal  B7 Antigens  Lymphocyte Activation  Membrane Proteins  Mice  Mice, Inbred C57BL  Mice, Knockout  Peripheral Tolerance  Receptors, Antigen, T-Cell  T-Lymphocytes  
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:  Ebright R.Y.;  Lee S.;  Wittner B.S.;  Niederhoffer K.L.;  Nicholson B.T.;  Bardia A.;  Truesdell S.;  Wiley D.F.;  Wesley B.;  Li S.;  Mai A.;  Aceto N.;  Vincent-Jordan N.;  Szabolcs A.;  Chirn B.;  Kreuzer J.;  Comaills V.;  Kalinich M.;  Haas W.;  Ting D.T.;  Toner M.;  Vasudevan S.;  Haber D.A.;  Maheswaran S.;  Micalizzi D.S.
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/28
CRISPR associated protein  epidermal growth factor receptor 2  Ki 67 antigen  ribosome protein  ribosome RNA  transcription factor E2F  ribosome protein  cancer  cell  gene expression  genetic engineering  protein  RNA  tumor  animal experiment  animal model  animal tissue  Article  biogenesis  bioluminescence  breast cancer  cell cycle progression  cell cycle regulation  cell proliferation  circulating tumor cell  controlled study  enzyme activation  epithelial mesenchymal transition  gene expression profiling  genetic transcription  human  human cell  lung metastasis  metastasis  microfluidics  mouse  nonhuman  overall survival  phenotype  priority journal  progression free survival  promoter region  protein expression  protein processing  protein synthesis  proteomics  RNA sequence  transcription regulation  animal  breast tumor  cancer transplantation  CRISPR Cas system  female  gene expression regulation  genetics  pathology  sequence analysis  tumor cell line  tumor embolism  Mus  Animals  Breast Neoplasms  Cell Line, Tumor  CRISPR-Cas Systems  Female  Gene Expression Regulation, Neoplastic  Humans  Mice  Neoplasm Metastasis  Neoplasm Transplantation  Neoplastic Cells, Circulating  Ribosomal Proteins  Sequence Analysis, RNA  
A lost world in Wallacea: Description of a montane archipelagic avifauna 期刊论文
, 2020, 卷号: 367, 期号: 6474
作者:  Rheindt F.E.;  Prawiradilaga D.M.;  Ashari H.;  Suparno;  Gwee C.Y.;  Lee G.W.X.;  Wu M.Y.;  Ng N.S.R.
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/28
avifauna  endemism  fieldwork  genomics  island biogeography  mountain environment  new species  phenotype  songbird  zoogeography  article  field work  human  Indonesia  nonhuman  Quaternary (period)  songbird  subspecies  animal  biodiversity  classification  island (geological)  phylogeography  species extinction  Greater Sunda Islands  Indonesia  Sulawesi  Sunda Isles  Wallacea  Animalia  Aves  Gabaza  Passeri  Animals  Biodiversity  Extinction, Biological  Indonesia  Islands  Phylogeography  Songbirds  
Pervasive functional translation of noncanonical human open reading frames 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Chen J.;  Brunner A.-D.;  Cogan J.Z.;  Nuñez J.K.;  Fields A.P.;  Adamson B.;  Itzhak D.N.;  Li J.Y.;  Mann M.;  Leonetti M.D.;  Weissman J.S.
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/28
messenger RNA  antigen  cell component  cell organelle  chemical binding  growth  phenotype  protein  Quaternary  RNA  Article  cell function  cell growth  cellular distribution  clustered regularly interspaced short palindromic repeat  gene sequence  genetic screening  HLA system  human  non-canonical base pairing  open reading frame  operon  priority journal  protein analysis  protein binding  protein function  transcriptomics  translation regulation  Mammalia  
An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者:  Reinhard K.;  Rengstl B.;  Oehm P.;  Michel K.;  Billmeier A.;  Hayduk N.;  Klein O.;  Kuna K.;  Ouchan Y.;  Wöll S.;  Christ E.;  Weber D.;  Suchan M.;  Bukur T.;  Birtel M.;  Jahndel V.;  Mroz K.;  Hobohm K.;  Kranz L.;  Diken M.;  Kühlcke K.;  Türeci Ö.;  Sahin U.
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/28
chimeric antigen receptor  claudin 6  RNA vaccine  antigen  cell component  protein  RNA  tumor  vaccine  animal cell  animal experiment  animal model  animal tissue  antigen presenting cell  antineoplastic activity  Article  cell stimulation  cell transport  chimeric antigen receptor T-cell immunotherapy  controlled study  drug efficacy  human  human cell  in vivo study  mouse  nonhuman  phenotype  priority journal  real time polymerase chain reaction  solid malignant neoplasm  therapy effect  vaccination coverage