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Integrating UPLC-Q-Exactive Orbitrap/MS, network pharmacology and experimental validation to reveal the potential mechanism of Tibetan medicine Rhodiola granules in improving myocardial ischemia-reperfusion injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 314
作者:  Xing, Nan;  Qin, Jing;  Ren, Dongsheng;  Du, Qinyun;  Li, Yuying;  Mi, Jiao;  Zhang, Fengming;  Ai, Li;  Zhang, Sanyin;  Zhang, Yi;  Wang, Shaohui
收藏  |  浏览/下载：7/0  |  提交时间：2024/03/01
UPLC-Q-exactive orbitrap  MS  Network pharmacology  Rhodiola granules  Myocardial ischemia-reperfusion injury  Experimental validation  
OCT4 induces embryonic pluripotency via STAT3 signaling and metabolic mechanisms 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 3
作者:  Stirparo G.G.;  Kurowski A.;  Yanagida A.;  Bates L.E.;  Strawbridge S.E.;  Hladkou S.;  Stuart H.T.;  Boroviak T.E.;  Silva J.C.R.;  Nichols J.
收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24
Pharmacological inhibition of MDA-9/Syntenin blocks breast cancer metastasis through suppression of IL-1β 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 21
作者:  Pradhan A.K.;  Maji S.;  Bhoopathi P.;  Talukdar S.;  Mannangatti P.;  Guo C.;  Wang X.-Y.;  Cartagena L.C.;  Idowu M.;  Landry J.W.;  Sarkar D.;  Emdad L.;  Cavenee W.K.;  Das S.K.;  Fisher P.B.
收藏  |  浏览/下载：130/0  |  提交时间：2022/02/22
Agonist of growth hormone–releasing hormone enhances retinal ganglion cell protection induced by macrophages after optic nerve injury 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 28
作者:  Cen L.-P.;  Ng T.K.;  Liang J.-J.;  Xu C.;  Zhuang X.;  Liu Y.-F.;  Chen S.-L.;  Xu Y.;  Yang Q.;  Yuan X.-L.;  Qin Y.J.;  Chan S.O.;  Chen H.;  Zhang M.;  Schally A.V.;  Pang C.P.
收藏  |  浏览/下载：29/0  |  提交时间：2022/02/22
Chemerin reverses the malignant phenotype and induces differentiation of human hepatoma SMMC7721 cells 期刊论文
ARCHIVES OF PHARMACAL RESEARCH, 2021, 卷号: 44, 期号: 2
作者:  Li, Ming;  Sun, Pengcheng;  Dong, Kaikai;  Xin, Ye;  TaiLulu, Aslee;  Li, Qinyu;  Sun, Jing;  Peng, Min;  Shi, Ping
收藏  |  浏览/下载：31/0  |  提交时间：2022/04/28
TRANSPEPTIDASE MESSENGER-RNA  HEPATOCELLULAR-CARCINOMA  SIGNAL TRANSDUCER  ACTIVATION  GROWTH  CANCER  STAT3  SUPPRESSES  EXPRESSION  INDICATOR  
HIV proviral DNA integration can drive T cell growth ex vivo 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 117, 期号: 52
作者:  Yoon J.K.;  Holloway J.R.;  Wells D.W.;  Kaku M.;  Jetton D.;  Brown R.;  Coffin J.M.
收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24
Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 2
作者:  Cui L.;  Moraga I.;  Lerbs T.;  van Neste C.;  Wilmes S.;  Tsutsumi N.;  Trotman-Grant A.C.;  Gakovic M.;  Andrews S.;  Gotlib J.;  Darmanis S.;  Enge M.;  Quake S.;  Hitchcock I.S.;  Piehler J.;  Christopher Garcia K.;  Wernig G.
收藏  |  浏览/下载：32/0  |  提交时间：2021/05/24
Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b 期刊论文
Science, 2020, 卷号: 368, 期号: 6488
作者:  Weber C.;  Zhou Y.;  Lee J.G.;  Looger L.L.;  Qian G.;  Ge C.;  Capel B.
收藏  |  浏览/下载：22/0  |  提交时间：2022/01/14
Computing cancer's weak spots 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Khamsi R.
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/28
ruxolitinib  STAT3 protein  antineoplastic agent  transcription factor  algorithm  cancer  computer simulation  disease treatment  drug development  medicine  Article  cancer cell  cancer radiotherapy  enzyme inhibition  gene activity  gene expression regulation  gene interaction  gene mutation  gene repression  gene targeting  human  laboratory test  malignant neoplasm  molecular dynamics  nonhuman  oncologist  priority journal  RNA sequencing  algorithm  genetics  mutation  neoplasm  personalized medicine  procedures  systems biology  Algorithms  Antineoplastic Agents  Humans  Mutation  Neoplasms  Precision Medicine  Systems Biology  Transcription Factors  
Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b 期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:  Weber C.;  Zhou Y.;  Lee J.G.;  Looger L.L.;  Qian G.;  Ge C.;  Capel B.
收藏  |  浏览/下载：24/0  |  提交时间：2020/07/28
STAT3 protein  calcium  histone demethylase  STAT3 protein  embryonic development  gene expression  sex determination  temperature effect  turtle  animal cell  animal experiment  Article  binding site  calcium transport  cell activation  chromatin immunoprecipitation  controlled study  dimerization  Dmrt1 gene  embryo  embryo development  environmental temperature  epigenetic repression  female  gene  gene activation  gene interaction  gene targeting  genetic transcription  gonad  high temperature  immunofluorescence test  Kdm6b gene  male  nonhuman  priority journal  protein phosphorylation  real time polymerase chain reaction  sex determination  signal transduction  temperature dependence  thermoregulation  transcription regulation  upregulation  Western blotting  animal  embryology  gene expression regulation  genetics  metabolism  phosphorylation  sex determination process  temperature  turtle  Reptilia  Trachemys scripta  Trachemys scripta elegans  Animals  Calcium  Female  Gene Expression Regulation, Developmental  Jumonji Domain-Containing Histone Demethylases  Male  Phosphorylation  Sex Determination Processes  STAT3 Transcription Factor  Temperature  Transcription, Genetic  Turtles