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文献类型
期刊论文 [119]
发表日期
2020 [119]
语种
英语 [119]
来源机构
Science [119]
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CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation
期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:
Muendlein H.I.
;
Jetton D.
;
Connolly W.M.
;
Eidell K.P.
;
Magri Z.
;
Smirnova I.
;
Poltorak A.
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/28
FLICE inhibitory protein
interleukin 1beta
lipopolysaccharide
messenger RNA
succinate dehydrogenase (ubiquinone)
Casp1 protein, mouse
caspase 8
Cflar protein, mouse
cryopyrin
FLICE inhibitory protein
IL1B protein, mouse
inflammasome
interleukin 1beta
interleukin 1beta converting enzyme
lipopolysaccharide
succinate dehydrogenase (ubiquinone)
cell
enzyme activity
inhibition
maturation
protein
animal cell
animal experiment
Article
bone marrow derived macrophage
cell death
cell protection
complex formation
controlled study
cytokine release
in vitro study
inflammation
mouse
nonhuman
priority journal
protein analysis
protein degradation
protein function
protein interaction
pyroptosis
animal
gene knockdown
genetics
immunology
macrophage
macrophage activation
metabolism
physiology
Murinae
Animals
CASP8 and FADD-Like Apoptosis Regulating Protein
Caspase 1
Caspase 8
Electron Transport Complex II
Gene Knockdown Techniques
Inflammasomes
Interleukin-1beta
Lipopolysaccharides
Macrophage Activation
Macrophages
Mice
NLR Family, Pyrin Domain-Containing 3 Protein
Pyroptosis
Computing cancer's weak spots
期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:
Khamsi R.
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/28
ruxolitinib
STAT3 protein
antineoplastic agent
transcription factor
algorithm
cancer
computer simulation
disease treatment
drug development
medicine
Article
cancer cell
cancer radiotherapy
enzyme inhibition
gene activity
gene expression regulation
gene interaction
gene mutation
gene repression
gene targeting
human
laboratory test
malignant neoplasm
molecular dynamics
nonhuman
oncologist
priority journal
RNA sequencing
algorithm
genetics
mutation
neoplasm
personalized medicine
procedures
systems biology
Algorithms
Antineoplastic Agents
Humans
Mutation
Neoplasms
Precision Medicine
Systems Biology
Transcription Factors
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Guthrie L.M.
;
Soma S.
;
Yuan S.
;
Silva A.
;
Zulkifli M.
;
Snavely T.C.
;
Greene H.F.
;
Nunez E.
;
Lynch B.
;
de Ville C.
;
Shanbhag V.
;
Lopez F.R.
;
Acharya A.
;
Petris M.J.
;
Kim B.-E.
;
Gohil V.M.
;
Sacchettini J.C.
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/28
copper
copper zinc superoxide dismutase
cytochrome c oxidase
dopamine beta monooxygenase
elesclomol
monophenol monooxygenase
protein lysine 6 oxidase
copper
cytochrome c oxidase
elesclomol
hydrazine derivative
copper
cytochrome
enzyme
enzyme activity
mitochondrion
mortality
mutation
pathology
rodent
survival
animal cell
animal experiment
animal model
animal tissue
Article
cohort analysis
controlled study
disease severity
drug mechanism
Golgi complex
H9c2(2-1) cell line
in vivo study
male
Menkes syndrome
mitochondrial dynamics
mortality rate
mouse
nerve degeneration
nonhuman
priority journal
secretory pathway
survival rate
animal
brain
cell line
degenerative disease
disease model
drug effect
genetics
knockout mouse
Menkes syndrome
metabolism
mitochondrion
pathology
rat
transport at the cellular level
Murinae
Mus
Animals
Biological Transport
Brain
Cell Line
Copper
Copper Transporter 1
Disease Models, Animal
Electron Transport Complex IV
Hydrazines
Male
Menkes Kinky Hair Syndrome
Mice
Mice, Knockout
Mitochondria
Neurodegenerative Diseases
Rats
Intravital imaging of mouse embryos
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Huang Q.
;
Cohen M.A.
;
Alsina F.C.
;
Devlin G.
;
Garrett A.
;
McKey J.
;
Havlik P.
;
Rakhilin N.
;
Wang E.
;
Xiang K.
;
Mathews P.
;
Wang L.
;
Bock C.
;
Ruthig V.
;
Wang Y.
;
Negrete M.
;
Wong C.W.
;
Murthy P.K.L.
;
Zhang S.
;
Daniel A.R.
;
Kirsch D.G.
;
Kang Y.
;
Capel B.
;
Asokan A.
;
Silver D.L.
;
Jaenisch R.
;
Shen X.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
cell
embryo
embryonic development
imaging method
physiology
animal cell
animal experiment
article
autophagy (cellular)
brain cell
cell division
chimera
controlled study
diffusion
electroporation
embryo
female
microscopy
mouse
mouse embryo
neural crest cell
neurotransmission
nonhuman
placenta
retina
uterus
vascularization
viral gene delivery system
A parapithecid stem anthropoid of African origin in the Paleogene of South America
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Seiffert E.R.
;
Tejedor M.F.
;
Fleagle J.G.
;
Novo N.M.
;
Cornejo F.M.
;
Bond M.
;
De Vries D.
;
Campbell K.E.
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/28
cladistics
dispersal
Eocene-Oligocene boundary
new record
Paleogene
phylogenetics
primate
rodent
article
cladistics
Eocene
nonhuman
Oligocene
phylogeny
primate
sea level
South America
Africa
Amazonia
Arabian Peninsula
Arabian Peninsula
Guatemala [Central America]
Peru
Santa Rosa
South America
Western Hemisphere
Caviomorpha
Mammalia
Parapithecidae
Primates
Rodentia
Simiiformes
Transcription polymerase-catalyzed emergence of novel RNA replicons
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Jain N.
;
Blauch L.R.
;
Szymanski M.R.
;
Das R.
;
Tang S.K.Y.
;
Yin Y.W.
;
Fire A.Z.
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/28
cell component
enzyme
enzyme activity
genetic analysis
RNA
article
bacteriophage
catalysis
DNA replication origin
heredity
in vitro study
nonhuman
plant seed
replicon
RNA replication
synthesis
transcription initiation
biocatalysis
biosynthesis
genetic transcription
metabolism
Animalia
Hepatitis delta virus
Viroids
bacteriophage T7 RNA polymerase
DNA directed RNA polymerase
RNA
viral protein
Biocatalysis
DNA-Directed RNA Polymerases
Replicon
RNA
Transcription, Genetic
Viral Proteins
Widespread receptor-driven modulation in peripheral olfactory coding
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Xu L.
;
Li W.
;
Voleti V.
;
Zou D.-J.
;
Hillman E.M.C.
;
Firestein S.
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/28
antagonism
cell component
detection method
odor
olfaction
protein
animal cell
animal experiment
article
excitation
high throughput analysis
male
microscopy
mouse
nonhuman
odor
olfactory epithelium
olfactory receptor neuron
animal
confocal microscopy
innervation
mutant mouse strain
olfactory mucosa
physiology
single cell analysis
acetophenone
acetophenone derivative
benzyl acetate
benzyl derivative
citral
fragrance
Acetophenones
Acyclic Monoterpenes
Animals
Benzyl Compounds
Mice
Mice, Mutant Strains
Microscopy, Confocal
Odorants
Olfactory Mucosa
Olfactory Receptor Neurons
Single-Cell Analysis
Smell
A neurodevelopmental origin of behavioral individuality in the Drosophila visual system
期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:
Linneweber G.A.
;
Andriatsilavo M.
;
Dutta S.B.
;
Bengochea M.
;
Hellbruegge L.
;
Liu G.
;
Ejsmont R.K.
;
Straw A.D.
;
Wernet M.
;
Hiesinger P.R.
;
Hassan B.A.
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/28
anatomy
asymmetry
brain
genome
neurology
orientation
visual analysis
article
brain
Drosophila melanogaster
human experiment
individuality
nerve cell
nonhuman
stochastic model
visual system
walking
anatomy and histology
animal
Drosophila melanogaster
genetic variation
genetics
growth, development and aging
nervous system development
orientation
physiology
visual field
visual system
Drosophila melanogaster
Animals
Brain
Drosophila melanogaster
Genetic Variation
Individuality
Neurogenesis
Orientation
Visual Fields
Visual Pathways
PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis
期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:
Wang Q.
;
Boshoff H.I.M.
;
Harrison J.R.
;
Ray P.C.
;
Green S.R.
;
Wyatt P.G.
;
Barry Iii C.E.
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/28
3,3 bis di(methylsulfonyl)propionamide
antiinfective agent
bacterial protein
glucose
glycerol
magnesium
phosphate
propionamide derivative
protein proline proline glutamate
protein proline proline glutamate 51
unclassified drug
amide
bacterial protein
lipid
phthiocerol dimycocerosate
propionamide
thiol derivative
cell component
chemical compound
membrane
mutation
protein
tuberculosis
antibiotic resistance
Article
bacterial cell
bacterial cell wall
bacterial growth
bacterial outer membrane
cell division
drug structure
Mycobacterium tuberculosis
nonhuman
nutrient uptake
priority journal
protein depletion
cell membrane
cell membrane permeability
chemistry
drug effect
gene deletion
genetics
metabolism
transport at the cellular level
Mycobacterium tuberculosis
Amides
Bacterial Proteins
Biological Transport
Cell Membrane
Cell Membrane Permeability
Drug Resistance, Bacterial
Gene Deletion
Glucose
Glycerol
Lipids
Mycobacterium tuberculosis
Sulfhydryl Compounds
Transcription factor AP2 controls cnidarian germ cell induction
期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:
DuBuc T.Q.
;
Schnitzler C.E.
;
Chrysostomou E.
;
McMahon E.T.
;
Febrimarsa
;
Gahan J.M.
;
Buggie T.
;
Gornik S.G.
;
Hanley S.
;
Barreira S.N.
;
Gonzalez P.
;
Baxevanis A.D.
;
Frank U.
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/28
transcription factor
transcription factor AP2
unclassified drug
clonal organism
gene expression
germ cell
invertebrate
physiological response
protein
adult
Article
cell fate
Cnidaria
embryo
female
genotype
germ cell
gonad development
Hydractinia symbiolongicarpus
male
nonhuman
phenotype
priority journal
protein expression
wild type
Animalia
Bilateria
Hydractinia symbiolongicarpus
Mammalia