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期刊论文 [5]
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2020 [5]
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英语 [5]
来源机构
Science [5]
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Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:
Dai W.
;
Zhang B.
;
Jiang X.-M.
;
Su H.
;
Li J.
;
Zhao Y.
;
Xie X.
;
Jin Z.
;
Peng J.
;
Liu F.
;
Li C.
;
Li Y.
;
Bai F.
;
Wang H.
;
Cheng X.
;
Cen X.
;
Hu S.
;
Yang X.
;
Wang J.
;
Liu X.
;
Xiao G.
;
Jiang H.
;
Rao Z.
;
Zhang L.-K.
;
Xu Y.
;
Yang H.
;
Liu H.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
aldehyde
antimicrobial activity
drug
enzyme activity
infectivity
inhibitor
reaction kinetics
viral disease
Coronavirus
SARS coronavirus
3C-like proteinase, Coronavirus
antivirus agent
cysteine proteinase
viral protein
animal
Betacoronavirus
chemical structure
chemistry
Chlorocebus aethiops
Coronavirus infection
dog
drug design
drug effect
enzyme active site
enzymology
female
human
male
mouse
pandemic
preclinical study
protein tertiary structure
Sprague Dawley rat
toxicity testing
Vero cell line
virus pneumonia
Animals
Antiviral Agents
Betacoronavirus
Catalytic Domain
Chlorocebus aethiops
Coronavirus Infections
Cysteine Endopeptidases
Dogs
Drug Design
Drug Evaluation, Preclinical
Female
Humans
Male
Mice
Molecular Structure
Pandemics
Pneumonia, Viral
Protein Structure, Tertiary
Rats, Sprague-Dawley
Toxicity Tests
Vero Cells
Viral Nonstructural Proteins
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance
期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:
ElTanbouly M.A.
;
Zhao Y.
;
Nowak E.
;
Li J.
;
Schaafsma E.
;
Le Mercier I.
;
Ceeraz S.
;
Lines J.L.
;
Peng C.
;
Carriere C.
;
Huang X.
;
Day M.
;
Koehn B.
;
Lee S.W.
;
Morales M.S.
;
Hogquist K.A.
;
Jameson S.C.
;
Mueller D.
;
Rothstein J.
;
Blazar B.R.
;
Cheng C.
;
Noelle R.J.
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/28
cell protein
interferon
kruppel like factor 2
T lymphocyte receptor
unclassified drug
V type immunoglobulin domain containing suppressor of T cell activation protein
B7 antigen
Dies1 protein, mouse
lymphocyte antigen receptor
membrane protein
monoclonal antibody
VSIR protein, human
biological development
cell
gene expression
heterogeneity
homeostasis
immune response
immunity
tolerance
acute graft versus host disease
animal cell
animal experiment
animal model
Article
CD4+ T lymphocyte
cell death
cell expansion
cell fate
cell heterogeneity
cell loss
cell survival
controlled study
female
gene
gene deletion
homeostasis
immunological tolerance
in vivo study
long term survival
male
mouse
nonhuman
phenotype
priority journal
protein expression
protein function
rheumatoid arthritis
RNA sequencing
systemic lupus erythematosus
T lymphocyte
T lymphocyte activation
T lymphocyte subpopulation
TCR gene
upregulation
VISTA gene
animal
C57BL mouse
genetics
immunological tolerance
immunology
knockout mouse
lymphocyte activation
physiology
T lymphocyte
Mus
Animals
Antibodies, Monoclonal
B7 Antigens
Lymphocyte Activation
Membrane Proteins
Mice
Mice, Inbred C57BL
Mice, Knockout
Peripheral Tolerance
Receptors, Antigen, T-Cell
T-Lymphocytes
Three-dimensional cross-nanowire networks recover full terahertz state
期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:
Peng K.
;
Jevtics D.
;
Zhang F.
;
Sterzl S.
;
Damry D.A.
;
Rothmann M.U.
;
Guilhabert B.
;
Strain M.J.
;
Tan H.H.
;
Herz L.M.
;
Fu L.
;
Dawson M.D.
;
Hurtado A.
;
Jagadish C.
;
Johnston M.B.
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/28
nanowire
electric field
imaging method
nanotechnology
polarization
quality control
semiconductor industry
Article
electric field
measurement
nanofabrication
nanotechnology
polarization
priority journal
terahertz radiation
A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:
Wu Y.
;
Wang F.
;
Shen C.
;
Peng W.
;
Li D.
;
Zhao C.
;
Li Z.
;
Li S.
;
Bi Y.
;
Yang Y.
;
Gong Y.
;
Xiao H.
;
Fan Z.
;
Tan S.
;
Wu G.
;
Tan W.
;
Lu X.
;
Fan C.
;
Wang Q.
;
Liu Y.
;
Zhang C.
;
Qi J.
;
Gao G.F.
;
Gao F.
;
Liu L.
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/28
Coronavirus
angiotensin converting enzyme 2
coronavirus spike glycoprotein
dipeptidyl carboxypeptidase
epitope
monoclonal antibody
neutralizing antibody
virus antibody
virus receptor
animal
chemistry
Coronavirus infection
disease model
human
immunology
isolation and purification
lung
mouse
pandemic
protein domain
serodiagnosis
virology
virus load
virus pneumonia
Animals
Antibodies, Monoclonal
Antibodies, Neutralizing
Antibodies, Viral
Coronavirus Infections
Disease Models, Animal
Humans
Immunodominant Epitopes
Lung
Mice
Neutralization Tests
Pandemics
Peptidyl-Dipeptidase A
Pneumonia, Viral
Protein Domains
Receptors, Virus
Spike Glycoprotein, Coronavirus
Viral Load
Aligned, high-density semiconducting carbon nanotube arrays for high-performance electronics
期刊论文
, 2020, 卷号: 368, 期号: 6493
作者:
Liu L.
;
Han J.
;
Xu L.
;
Zhou J.
;
Zhao C.
;
Ding S.
;
Shi H.
;
Xiao M.
;
Ding L.
;
Ma Z.
;
Jin C.
;
Zhang Z.
;
Peng L.-M.
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/28
array
carbon nanotube
electronic commerce
electronic equipment
nanotube
performance assessment
silicon
superconductivity