CCPortal

浏览/检索结果: 共7条,第1-7条 帮助

已选(0)清除 条数/页:   排序方式:
Fertilization effects on soil ecology strongly depend on the genotype in a willow (Salix spp.) plantation 期刊论文
, 2020, 卷号: 466
作者:  Baum C.;  Amm T.;  Kahle P.;  Weih M.
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/28
Aggregates  Ecology  Forestry  Fungi  Magnesium  Organic carbon  Phosphorus  Aggregate stability  Arbuscular mycorrhizal  Arbuscular mycorrhizal fungi  Dehydrogenase activity  Short rotation coppice  Soil aggregate stability  Soil microbial activities  Soil organic carbon  Soils  aggregate stability  arbuscular mycorrhiza  coppice  deciduous tree  environmental indicator  enzyme activity  fertilizer application  fungus  genotype  microbial activity  phosphorus  plantation  protein  soil carbon  soil ecosystem  Ecology  Fertilization  Forestry  Fungi  Magnesium  Phosphorus  Salix  Soil  Sweden  Fungi  Salix  Salix arbusculoides  
A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity 期刊论文
, 2020, 卷号: 369, 期号: 6499
作者:  Meeske A.J.;  Jia N.;  Cassel A.K.;  Kozlova A.;  Liao J.;  Wiedmann M.;  Patel D.J.;  Marraffini L.A.
收藏  |  浏览/下载:40/0  |  提交时间:2020/07/28
CRISPR associated protein  endonuclease  guide RNA  viral protein  virus RNA  bacteriophage  clustered regularly interspaced short palindromic repeat  CRISPR Cas system  DNA cleavage  genetics  Listeria  metabolism  RNA stability  virology  Bacteriophages  Clustered Regularly Interspaced Short Palindromic Repeats  CRISPR-Associated Proteins  CRISPR-Cas Systems  DNA Cleavage  Endonucleases  Listeria  RNA Stability  RNA, Guide  RNA, Viral  Viral Proteins  
Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance 期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:  Freeman S.A.;  Uderhardt S.;  Saric A.;  Collins R.F.;  Buckley C.M.;  Mylvaganam S.;  Boroumand P.;  Plumb J.;  Germain R.N.;  Ren D.;  Grinstein S.
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/28
cation channel  chemokine receptor CCR2  chloride  colony stimulating factor 1  epidermal growth factor  epidermal growth factor receptor  lipid  sialoadhesin  sodium ion  tetrandrine  two pore channel  unclassified drug  calcium channel  lipid  Mcoln1 protein, mouse  sodium  TPCN1 protein, mouse  TPCN2 protein, mouse  transient receptor potential channel  cation  homeostasis  immune system  protein  recycling  animal experiment  Article  bone marrow derived macrophage  cell vacuole  cell volume  channel gating  chloride transport  concentration (parameter)  controlled study  endocytosis  extracellular fluid  extracellular space  homeostasis  human  human cell  human tissue  immunosurveillance  in vitro study  internalization  ion current  knockout mouse  macropinocytosis  mouse  nonhuman  priority journal  protein stability  RNA interference  sodium transport  tonoplast  animal  cell organelle  endosome  genetics  immunology  ion transport  macrophage  metabolism  osmosis  physiology  pinocytosis  Animals  Calcium Channels  Endosomes  Immunologic Surveillance  Ion Transport  Lipids  Macrophages  Mice  Mice, Knockout  Organelles  Osmosis  Pinocytosis  Sodium  Transient Receptor Potential Channels  Vacuoles  
Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Wingler L.M.;  Skiba M.A.;  McMahon C.;  Staus D.P.;  Kleinhenz A.L.W.;  Suomivuori C.-M.;  Latorraca N.R.;  Dror R.O.;  Lefkowitz R.J.;  Kruse A.C.
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28
angiotensin 1 receptor  beta arrestin  G protein coupled receptor  biochemistry  crystal chemistry  crystal structure  physiological response  protein  signaling  allosterism  alpha helix  amino terminal sequence  Article  binding affinity  binding site  carboxy terminal sequence  conformational transition  crystallization  hydrogen bond  molecular dynamics  priority journal  protein binding  protein conformation  protein protein interaction  protein stability  signal transduction  thermostability  
Structural insights into immunoglobulin M 期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:  Li Y.;  Wang G.;  Li N.;  Wang Y.;  Zhu Q.;  Chu H.;  Wu W.;  Tan Y.;  Yu F.;  Su X.-D.;  Gao N.;  Xiao J.
收藏  |  浏览/下载:43/0  |  提交时间:2020/07/28
immunoglobulin M  secretory component  antibody  immunity  molecular analysis  polymer  protein  Article  binding site  conformational transition  cryoelectron microscopy  crystal structure  human  hydrophobicity  nonhuman  oligomerization  priority journal  protein assembly  protein domain  protein function  protein interaction  protein stability  protein structure  protein transport  surface area  
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved a-ketoamide inhibitors 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Zhang L.;  Lin D.;  Sun X.;  Curth U.;  Drosten C.;  Sauerhering L.;  Becker S.;  Rox K.;  Hilgenfeld R.
收藏  |  浏览/下载:41/0  |  提交时间:2020/07/28
alanine  alpha ketoamide inhibitor  antivirus agent  isoleucine  leucine  proteinase  Severe acute respiratory syndrome coronavirus 2 main protease  threonine  unclassified drug  crystal structure  drug  enzyme  enzyme activity  inhibitor  reaction kinetics  amino acid sequence  animal cell  animal experiment  animal tissue  antiviral activity  Article  catalysis  catalytic efficiency  controlled study  crystal structure  dimerization  dissociation constant  drug clearance  drug design  drug distribution  drug half life  drug potency  drug protein binding  drug solubility  drug structure  EC50  enzyme inhibition  human  human cell  hydrogen bond  hydrophobicity  IC50  maximum concentration  mean residence time  metabolic stability  mouse  nonhuman  priority journal  protein structure  RNA replication  SARS coronavirus  Severe acute respiratory syndrome coronavirus 2  viral tropism  virus inhibition  Coronavirus  SARS coronavirus  
Structural basis of second-generation HIV integrase inhibitor action and viral resistance 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:  Cook N.J.;  Li W.;  Berta D.;  Badaoui M.;  Ballandras-Colas A.;  Nans A.;  Kotecha A.;  Rosta E.;  Engelman A.N.;  Cherepanov P.
收藏  |  浏览/下载:38/0  |  提交时间:2020/07/28
bictegravir  dolutegravir  lens epithelium derived growth factor  magnesium ion  bictegravir  dolutegravir  fused heterocyclic rings  glutamine  glycine  histidine  integrase  integrase inhibitor  magnesium  serine  acquired immune deficiency syndrome  amino acid  drug  human immunodeficiency virus  inhibitor  protein  ultrastructure  virus  amino acid substitution  amino terminal sequence  Article  carboxy terminal sequence  cryoelectron microscopy  DNA binding  drug design  drug protein binding  drug structure  enzyme active site  gene mutation  Human immunodeficiency virus 1  in vitro study  molecular dynamics  molecular stability  nonhuman  pharmacophore  polarization  priority journal  protonation  virus resistance  antiviral resistance  chemistry  genetics  human  mutation  procedures  single molecule imaging  Amino Acid Substitution  Catalytic Domain  Cryoelectron Microscopy  Drug Resistance, Viral  Glutamine  Glycine  Heterocyclic Compounds, 3-Ring  Heterocyclic Compounds, 4 or More Rings  Histidine  HIV Integrase  HIV Integrase Inhibitors  Humans  Magnesium  Mutation  Serine  Single Molecule Imaging