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Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p
期刊论文
Science Bulletin, 2021
作者:
Tong Y.
;
Zhang J.
;
Sun N.
;
Wang X.-M.
;
Wei Q.
;
Zhang Y.
;
Huang R.
;
Pu Y.
;
Dai H.
;
Ren B.
;
Pei G.
;
Song F.
;
Zhu G.
;
Wang X.
;
Xia X.
;
Chen X.
;
Jiang L.
;
Wang S.
;
Ouyang L.
;
Xie N.
;
Zhang B.
;
Jiang Y.
;
Liu X.
;
Calderone R.
;
Bai F.
;
Zhang L.
;
Alterovitz G.
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2021/09/01
Berberine
Candida albicans
Drug excretion transporter
Mitochondria
Multidrug-resistance
Transcriptome Analysis Reveals Genes Involved in Thermogenesis in Two Cold-Exposed Sheep Breeds
期刊论文
GENES, 2021, 卷号: 12, 期号: 3
作者:
Jiao, Dan
;
Ji, Kaixi
;
Liu, Hu
;
Wang, Wenqiang
;
Wu, Xiukun
;
Zhou, Jianwei
;
Zhang, Yunsheng
;
Zhou, Huitong
;
Hickford, Jon G. H.
;
Degen, Allan A.
;
Yang, Guo
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/04/28
BROWN-ADIPOSE-TISSUE
DIET-INDUCED OBESITY
ACTIVATED PROTEIN-KINASE
SARCOPLASMIC-RETICULUM
ENERGY-EXPENDITURE
LIPOPROTEIN-LIPASE
INSULIN-RESISTANCE
FATTY-ACIDS
MITOCHONDRIA
TEMPERATURE
T cells with dysfunctional mitochondria induce multimorbidity and premature senescence
期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:
Desdín-Micó G.
;
Soto-Heredero G.
;
Aranda J.F.
;
Oller J.
;
Carrasco E.
;
Gabandé-Rodríguez E.
;
Blanco E.M.
;
Alfranca A.
;
Cussó L.
;
Desco M.
;
Ibañez B.
;
Gortazar A.R.
;
Fernández-Marcos P.
;
Navarro M.N.
;
Hernaez B.
;
Alcamí A.
;
Baixauli F.
;
Mittelbrunn M.
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/28
cardiovascular disease
enzyme activity
gene expression
metabolism
mitochondrial DNA
morbidity
senescence
tumor
Mus
DNA binding protein
mitochondrial protein
mitochondrial transcription factor A
nicotinamide adenine dinucleotide
transcription factor
tumor necrosis factor
animal
cytokine release syndrome
female
fitness
gene deletion
genetics
immunology
inflammation
longevity
male
metabolism
mitochondrion
mouse
multiple chronic conditions
mutant mouse strain
premature aging
T lymphocyte
ultrastructure
Aging, Premature
Animals
Cytokine Release Syndrome
DNA-Binding Proteins
Female
Gene Deletion
Inflammation
Longevity
Male
Mice
Mice, Mutant Strains
Mitochondria
Mitochondrial Proteins
Multimorbidity
NAD
Physical Fitness
T-Lymphocytes
Transcription Factors
Tumor Necrosis Factor-alpha
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Guthrie L.M.
;
Soma S.
;
Yuan S.
;
Silva A.
;
Zulkifli M.
;
Snavely T.C.
;
Greene H.F.
;
Nunez E.
;
Lynch B.
;
de Ville C.
;
Shanbhag V.
;
Lopez F.R.
;
Acharya A.
;
Petris M.J.
;
Kim B.-E.
;
Gohil V.M.
;
Sacchettini J.C.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
copper
copper zinc superoxide dismutase
cytochrome c oxidase
dopamine beta monooxygenase
elesclomol
monophenol monooxygenase
protein lysine 6 oxidase
copper
cytochrome c oxidase
elesclomol
hydrazine derivative
copper
cytochrome
enzyme
enzyme activity
mitochondrion
mortality
mutation
pathology
rodent
survival
animal cell
animal experiment
animal model
animal tissue
Article
cohort analysis
controlled study
disease severity
drug mechanism
Golgi complex
H9c2(2-1) cell line
in vivo study
male
Menkes syndrome
mitochondrial dynamics
mortality rate
mouse
nerve degeneration
nonhuman
priority journal
secretory pathway
survival rate
animal
brain
cell line
degenerative disease
disease model
drug effect
genetics
knockout mouse
Menkes syndrome
metabolism
mitochondrion
pathology
rat
transport at the cellular level
Murinae
Mus
Animals
Biological Transport
Brain
Cell Line
Copper
Copper Transporter 1
Disease Models, Animal
Electron Transport Complex IV
Hydrazines
Male
Menkes Kinky Hair Syndrome
Mice
Mice, Knockout
Mitochondria
Neurodegenerative Diseases
Rats
Metabolomics and mass spectrometry imaging reveal channeled de novo purine synthesis in cells
期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:
Pareek V.
;
Tian H.
;
Winograd N.
;
Benkovic S.J.
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/28
adenosine phosphate
guanosine phosphate
multienzyme complex
nucleotide
purine
purine
purine derivative
cell
experimental study
imaging method
mass spectrometry
metabolism
protein
Article
biochemistry
enzyme assay
gas cluster ion beam secondary ion mass spectrometry
image analysis
mass spectrometry
metabolomics
mitochondrion
molecular imaging
molecular probe
priority journal
purine synthesis
reaction analysis
single cell analysis
biosynthesis
fluorescence imaging
HeLa cell line
human
metabolism
metabolomics
procedures
secondary ion mass spectrometry
HeLa Cells
Humans
Metabolomics
Mitochondria
Multienzyme Complexes
Optical Imaging
Purines
Single-Cell Analysis
Spectrometry, Mass, Secondary Ion
Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division
期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:
Nagashima S.
;
Tábara L.-C.
;
Tilokani L.
;
Paupe V.
;
Anand H.
;
Pogson J.H.
;
Zunino R.
;
McBride H.M.
;
Prudent J.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
adenosine diphosphate ribosylation factor 1
dynamin related protein 1
mitochondrial protein
phosphatidylinositol 4 kinase IIIbeta
phosphatidylinositol 4 phosphate
phosphatidylinositol kinase
unclassified drug
adenosine diphosphate ribosylation factor 1
ARF1 protein, human
DNM1L protein, human
dynamin
phosphatidylinositol 4-phosphate
phosphatidylinositol kinase
polyphosphoinositide
cell component
cell organelle
chemical compound
enzyme
enzyme activity
mitochondrion
protein
Article
controlled study
COS-7 cell line
endoplasmic reticulum
fibroblast
gene silencing
HeLa cell line
human
human cell
membrane microdomain
mitochondrial division
mitochondrial dynamics
mitochondrial scission
priority journal
protein localization
trans Golgi network
U2OS cell line
animal
cell line
Chlorocebus aethiops
CV-1 cell line
genetics
metabolism
mitochondrial membrane
mitochondrion
RNA interference
trans Golgi network
ultrastructure
Mammalia
1-Phosphatidylinositol 4-Kinase
ADP-Ribosylation Factor 1
Animals
Cell Line
Chlorocebus aethiops
COS Cells
Dynamins
Endoplasmic Reticulum
HeLa Cells
Humans
Membrane Microdomains
Mitochondria
Mitochondrial Dynamics
Mitochondrial Membranes
Phosphatidylinositol Phosphates
RNA Interference
trans-Golgi Network
Interleukin-13 drives metabolic conditioning of muscle to endurance exercise
期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:
Knudsen N.H.
;
Stanya K.J.
;
Hyde A.L.
;
Chalom M.M.
;
Alexander R.K.
;
Liou Y.-H.
;
Starost K.A.
;
Gangl M.R.
;
Jacobi D.
;
Liu S.
;
Sopariwala D.H.
;
Fonseca-Pereira D.
;
Li J.
;
Hu F.B.
;
Garrett W.S.
;
Narkar V.A.
;
Ortlund E.A.
;
Kim J.H.
;
Paton C.M.
;
Cooper J.A.
;
Lee C.-H.
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2020/07/28
glucose
interleukin 13
interleukin 13 receptor alpha1
interleukin 6
STAT3 protein
fatty acid
glycogen
interleukin 13
interleukin 13 receptor alpha1
STAT3 protein
Stat3 protein, mouse
fatty acid
metabolism
muscle
oxidation
physiological response
protein
respiration
aerobic exercise
animal cell
animal experiment
animal tissue
Article
C2C12 cell line
cohort analysis
controlled study
endurance training
energy metabolism
ex vivo study
exercise intensity
female
gastrocnemius muscle
glucose tolerance
human
in vitro study
male
mitochondrial biogenesis
mitochondrial dynamics
mitochondrial respiration
mouse
muscle metabolism
muscle mitochondrion
nonhuman
obesity
priority journal
protein blood level
protein expression
running
sedentary lifestyle
signal transduction
treadmill exercise
adaptation
animal
blood
C57BL mouse
cell line
endurance
genetics
glucose blood level
immunology
knockout mouse
metabolism
myoblast
oxidation reduction reaction
skeletal muscle
Mus
Adaptation, Physiological
Animals
Blood Glucose
Cell Line
Fatty Acids
Female
Glycogen
Humans
Interleukin-13
Interleukin-13 Receptor alpha1 Subunit
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Mitochondria, Muscle
Muscle, Skeletal
Myoblasts
Oxidation-Reduction
Physical Conditioning, Animal
Physical Endurance
Running
STAT3 Transcription Factor
The histone H3-H4 tetramer is a copper reductase enzyme
期刊论文
, 2020, 卷号: 369, 期号: 6499
作者:
Attar N.
;
Campos O.A.
;
Vogelauer M.
;
Cheng C.
;
Xue Y.
;
Schmollinger S.
;
Salwinski L.
;
Mallipeddi N.V.
;
Boone B.A.
;
Yen L.
;
Yang S.
;
Zikovich S.
;
Dardine J.
;
Carey M.F.
;
Merchant S.S.
;
Kurdistani S.K.
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/28
copper
copper oxidase
copper zinc superoxide dismutase
histone
MAC1 protein, S cerevisiae
nuclear protein
oxidoreductase
recombinant protein
Saccharomyces cerevisiae protein
transcription factor
animal
biocatalysis
chemistry
enzyme active site
enzymology
gain of function mutation
genetics
metabolism
mitochondrion
protein multimerization
Saccharomyces cerevisiae
Xenopus laevis
Animals
Biocatalysis
Catalytic Domain
Copper
Gain of Function Mutation
Histones
Mitochondria
Nuclear Proteins
Oxidoreductases
Protein Multimerization
Recombinant Proteins
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Superoxide Dismutase-1
Transcription Factors
Xenopus laevis
Widespread impact of horizontal gene transfer on plant colonization of land
期刊论文
NATURE COMMUNICATIONS, 2012, 卷号: 3
作者:
Yue, Jipei
;
Hu, Xiangyang
;
Sun, Hang
;
Yang, Yongping
;
Huang, Jinling
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/06/21
ARABIDOPSIS
EVOLUTION
ORIGIN
GENOME
DNA
PHOTOSYNTHESIS
MITOCHONDRIA
MYCORRHIZAS
PHYLOGENY
PROTEIN