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Population size mediates the contribution of high-rate and large-benefit mutations to parallel evolution 期刊论文
Nature Ecology & Evolution, 2022, 卷号: 6, 期号: 4
作者:  Schenk M.F.;  Zwart M.P.;  Hwang S.;  Ruelens P.;  Severing E.;  Krug J.;  de Visser J.A.G.M.
收藏  |  浏览/下载:83/0  |  提交时间:2022/06/13
Taking a breather: Characterizing the role of H+/Ca transport in anoxia tolerance 项目
项目编号: 2042513, 资助机构: US-NSF, 2021-05/3
负责人:  Kendal Hirschi
收藏  |  浏览/下载:8/0  |  提交时间:2021/10/12
Negative selection on human genes underlying inborn errors depends on disease outcome and both the mode and mechanism of inheritance 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 3
作者:  Rapaport F.;  Boisson B.;  Gregor A.;  Béziat V.;  Boisson-Dupuis S.;  Bustamante J.;  Jouanguy E.;  Puel A.;  Rosain J.;  Zhang Q.;  Zhang S.-Y.;  Gleeson J.G.;  Quintana-Murci L.;  Casanova J.-L.;  Abel L.;  Patin E.
收藏  |  浏览/下载:35/0  |  提交时间:2021/05/24
Early role for a Na+,K+-ATPase (ATP1A3) in brain development 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 25
作者:  Smith R.S.;  Florio M.;  Akula S.K.;  Neil J.E.;  Wang Y.;  Sean Hill R.;  Goldman M.;  Mullally C.D.;  Reed N.;  Bello-Espinosa L.;  Flores-Sarnat L.;  Monteiro F.P.;  Erasmo C.B.;  Vairo F.P.E.;  Morava E.;  James Barkovich A.;  Gonzalez-Heydrich J.;  Brownstein C.A.;  McCarroll S.A.;  Walsh C.A.
收藏  |  浏览/下载:23/0  |  提交时间:2022/02/22
Mucosal acidosis elicits a unique molecular signature in epithelia and intestinal tissue mediated by GPR31-induced CREB phosphorylation 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 20
作者:  Cartwright I.M.;  Dowdell A.S.;  Lanis J.M.;  Brink K.R.;  Mu A.;  Kostelecky R.E.;  Schaefer R.E.M.;  Welch N.;  Onyiah J.C.;  Hall C.H.T.;  Gerich M.E.;  Tabor J.J.;  Colgan S.P.
收藏  |  浏览/下载:28/0  |  提交时间:2022/02/22
AP-3-dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 20
作者:  Kook S.;  Wang P.;  Meng S.;  Jetter C.S.;  Sucre J.M.S.;  Benjamin J.T.;  Gokey J.J.;  Hanby H.A.;  Jaume A.;  Goetzl L.;  Marks M.S.;  Guttentag S.H.
收藏  |  浏览/下载:25/0  |  提交时间:2022/02/22
Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 33
作者:  Schwer B.;  Garg A.;  Jacewicz A.;  Shuman S.
收藏  |  浏览/下载:126/0  |  提交时间:2022/02/22
Sulfated glycosaminoglycans mediate prion-like behavior of p53 aggregates 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 117, 期号: 52
作者:  Iwahashi N.;  Ikezaki M.;  Nishikawa T.;  Namba N.;  Ohgita T.;  Saito H.;  Ihara Y.;  Shimanouchi T.;  Ino K.;  Uchimura K.;  Nishitsuji K.
收藏  |  浏览/下载:52/0  |  提交时间:2021/05/24
Enhanced Ca2+ signaling, mild primary aldosteronism, and hypertension in a familial hyperaldosteronism mouse model (Cacna1hM1560V/+) 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 17
作者:  Seidel E.;  Schewe J.;  Zhang J.;  Dinh H.A.;  Forslund S.K.;  Markó L.;  Hellmig N.;  Peters J.;  Muller D.N.;  Lifton R.P.;  Nottoli T.;  Stölting G.;  Scholl U.I.
收藏  |  浏览/下载:22/0  |  提交时间:2021/05/24
Modeling DNA trapping of anticancer therapeutic targets using missense mutations identifies dominant synthetic lethal interactions 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 14
作者:  Hamza A.;  Amitzi L.;  Ma L.;  Driessen M.R.M.;  O'Neil N.J.;  Hieter P.
收藏  |  浏览/下载:19/0  |  提交时间:2021/05/24