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Tibetan highland barley fiber improves obesity and regulates gut microbiota in high-fat diet-fed mice 期刊论文
FOOD BIOSCIENCE, 2023, 卷号: 53
作者:  Gan, Linyao;  Han, Jing;  Li, Chenyao;  Tang, Jing;  Wang, Xuebing;  Ma, Yue;  Chen, Yefu;  Xiao, Dongguang;  Guo, Xuewu
收藏  |  浏览/下载：2/0  |  提交时间：2024/03/01
Gut microbiota  Highland barley  Fiber  Obesity  C57BL  6J mice  
Phenotypic and genomic adaptations to the extremely high elevation in plateau zokor (Myospalax baileyi) 期刊论文
MOLECULAR ECOLOGY, 2021, 卷号: 30, 期号: 22
作者:  Zhang, Tao;  Chen, Jie;  Zhang, Jia;  Guo, Yuan-Ting;  Zhou, Xin;  Li, Meng-Wen;  Zheng, Zhi-Zhong;  Zhang, Tong-Zuo;  Murphy, Robert W.;  Nevo, Eviatar;  Shi, Peng
收藏  |  浏览/下载：18/0  |  提交时间：2022/04/28
HIGH-ALTITUDE ADAPTATION  NATURAL-SELECTION  GENETIC ADAPTATION  REVEALS ADAPTATION  MURINE MODELS  MOLE-RATS  HEART  MUTATIONS  MICE  ASSOCIATION  
Effects of parasites and predators on nociception: decreases analgesia reduces overwinter survival in root voles (Rodentia: Cricetidae) 期刊论文
ZOOLOGIA, 2021, 卷号: 38
作者:  Yang, Yuan-Gang;  Shang, Guo-Zhen;  Wu, Xue-Qin;  Chen, Hui-Qing;  Wu, Yan;  Cao, Yi-Fan;  Bian, Jiang-Hui
收藏  |  浏览/下载：140/0  |  提交时间：2022/04/28
BODY CONDITION  ANTIPREDATOR BEHAVIOR  POPULATION-DYNAMICS  MICROTUS-OECONOMUS  MATERNAL STRESS  WINTER SURVIVAL  SEX-DIFFERENCES  RISK  MICE  VULNERABILITY  
Imaging strategies using cyanine probes and materials for biomedical visualization of live animals 期刊论文
COORDINATION CHEMISTRY REVIEWS, 2021, 卷号: 447
作者:  Fei, Guiqiang;  Ma, Siyue;  Wang, Chao;  Chen, Tao;  Li, Yulin;  Liu, Yuxia;  Tang, Bo;  James, Tony D.;  Chen, Guang
收藏  |  浏览/下载：28/0  |  提交时间：2022/04/28
INFRARED FLUORESCENT-PROBE  HIGHLY SELECTIVE DETECTION  IN-VIVO  SUPEROXIDE ANION  PHOTODYNAMIC THERAPY  ENHANCED PROBE  CELLS  MICE  PHOTOSTABILITY  GLUTATHIONE  
CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Muendlein H.I.;  Jetton D.;  Connolly W.M.;  Eidell K.P.;  Magri Z.;  Smirnova I.;  Poltorak A.
收藏  |  浏览/下载：41/0  |  提交时间：2020/07/28
FLICE inhibitory protein  interleukin 1beta  lipopolysaccharide  messenger RNA  succinate dehydrogenase (ubiquinone)  Casp1 protein, mouse  caspase 8  Cflar protein, mouse  cryopyrin  FLICE inhibitory protein  IL1B protein, mouse  inflammasome  interleukin 1beta  interleukin 1beta converting enzyme  lipopolysaccharide  succinate dehydrogenase (ubiquinone)  cell  enzyme activity  inhibition  maturation  protein  animal cell  animal experiment  Article  bone marrow derived macrophage  cell death  cell protection  complex formation  controlled study  cytokine release  in vitro study  inflammation  mouse  nonhuman  priority journal  protein analysis  protein degradation  protein function  protein interaction  pyroptosis  animal  gene knockdown  genetics  immunology  macrophage  macrophage activation  metabolism  physiology  Murinae  Animals  CASP8 and FADD-Like Apoptosis Regulating Protein  Caspase 1  Caspase 8  Electron Transport Complex II  Gene Knockdown Techniques  Inflammasomes  Interleukin-1beta  Lipopolysaccharides  Macrophage Activation  Macrophages  Mice  NLR Family, Pyrin Domain-Containing 3 Protein  Pyroptosis  
Efficient One-Step Separation of Five Flavonoids from the Crude Extract of the Waste Pomace of Sea Buckthorn Berries through Counter-Current Chromatography 期刊论文
JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2020
作者:  Chen, Tao;  Wang, Shuo;  Li, Hongmei;  Shen, Cheng;  Yan, Shuping;  Wei, Yangfei;  Song, Zhibo;  Li, Peipei;  Li, Yulin
收藏  |  浏览/下载：171/0  |  提交时间：2022/04/28
HIPPOPHAE-RHAMNOIDES L.  PREPARATIVE SEPARATION  LIQUID-CHROMATOGRAPHY  PURIFICATION  MICE  
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Dai W.;  Zhang B.;  Jiang X.-M.;  Su H.;  Li J.;  Zhao Y.;  Xie X.;  Jin Z.;  Peng J.;  Liu F.;  Li C.;  Li Y.;  Bai F.;  Wang H.;  Cheng X.;  Cen X.;  Hu S.;  Yang X.;  Wang J.;  Liu X.;  Xiao G.;  Jiang H.;  Rao Z.;  Zhang L.-K.;  Xu Y.;  Yang H.;  Liu H.
收藏  |  浏览/下载：36/0  |  提交时间：2020/07/28
aldehyde  antimicrobial activity  drug  enzyme activity  infectivity  inhibitor  reaction kinetics  viral disease  Coronavirus  SARS coronavirus  3C-like proteinase, Coronavirus  antivirus agent  cysteine proteinase  viral protein  animal  Betacoronavirus  chemical structure  chemistry  Chlorocebus aethiops  Coronavirus infection  dog  drug design  drug effect  enzyme active site  enzymology  female  human  male  mouse  pandemic  preclinical study  protein tertiary structure  Sprague Dawley rat  toxicity testing  Vero cell line  virus pneumonia  Animals  Antiviral Agents  Betacoronavirus  Catalytic Domain  Chlorocebus aethiops  Coronavirus Infections  Cysteine Endopeptidases  Dogs  Drug Design  Drug Evaluation, Preclinical  Female  Humans  Male  Mice  Molecular Structure  Pandemics  Pneumonia, Viral  Protein Structure, Tertiary  Rats, Sprague-Dawley  Toxicity Tests  Vero Cells  Viral Nonstructural Proteins  
T cells with dysfunctional mitochondria induce multimorbidity and premature senescence 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Desdín-Micó G.;  Soto-Heredero G.;  Aranda J.F.;  Oller J.;  Carrasco E.;  Gabandé-Rodríguez E.;  Blanco E.M.;  Alfranca A.;  Cussó L.;  Desco M.;  Ibañez B.;  Gortazar A.R.;  Fernández-Marcos P.;  Navarro M.N.;  Hernaez B.;  Alcamí A.;  Baixauli F.;  Mittelbrunn M.
收藏  |  浏览/下载：37/0  |  提交时间：2020/07/28
cardiovascular disease  enzyme activity  gene expression  metabolism  mitochondrial DNA  morbidity  senescence  tumor  Mus  DNA binding protein  mitochondrial protein  mitochondrial transcription factor A  nicotinamide adenine dinucleotide  transcription factor  tumor necrosis factor  animal  cytokine release syndrome  female  fitness  gene deletion  genetics  immunology  inflammation  longevity  male  metabolism  mitochondrion  mouse  multiple chronic conditions  mutant mouse strain  premature aging  T lymphocyte  ultrastructure  Aging, Premature  Animals  Cytokine Release Syndrome  DNA-Binding Proteins  Female  Gene Deletion  Inflammation  Longevity  Male  Mice  Mice, Mutant Strains  Mitochondria  Mitochondrial Proteins  Multimorbidity  NAD  Physical Fitness  T-Lymphocytes  Transcription Factors  Tumor Necrosis Factor-alpha  
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:  Guthrie L.M.;  Soma S.;  Yuan S.;  Silva A.;  Zulkifli M.;  Snavely T.C.;  Greene H.F.;  Nunez E.;  Lynch B.;  de Ville C.;  Shanbhag V.;  Lopez F.R.;  Acharya A.;  Petris M.J.;  Kim B.-E.;  Gohil V.M.;  Sacchettini J.C.
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/28
copper  copper zinc superoxide dismutase  cytochrome c oxidase  dopamine beta monooxygenase  elesclomol  monophenol monooxygenase  protein lysine 6 oxidase  copper  cytochrome c oxidase  elesclomol  hydrazine derivative  copper  cytochrome  enzyme  enzyme activity  mitochondrion  mortality  mutation  pathology  rodent  survival  animal cell  animal experiment  animal model  animal tissue  Article  cohort analysis  controlled study  disease severity  drug mechanism  Golgi complex  H9c2(2-1) cell line  in vivo study  male  Menkes syndrome  mitochondrial dynamics  mortality rate  mouse  nerve degeneration  nonhuman  priority journal  secretory pathway  survival rate  animal  brain  cell line  degenerative disease  disease model  drug effect  genetics  knockout mouse  Menkes syndrome  metabolism  mitochondrion  pathology  rat  transport at the cellular level  Murinae  Mus  Animals  Biological Transport  Brain  Cell Line  Copper  Copper Transporter 1  Disease Models, Animal  Electron Transport Complex IV  Hydrazines  Male  Menkes Kinky Hair Syndrome  Mice  Mice, Knockout  Mitochondria  Neurodegenerative Diseases  Rats  
An intrinsic oscillator drives the blood stage cycle of the malaria parasite Plasmodium falciparum 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Smith L.M.;  Motta F.C.;  Chopra G.;  Moch J.K.;  Nerem R.R.;  Cummins B.;  Roche K.E.;  Kelliher C.M.;  Leman A.R.;  Harer J.;  Gedeon T.;  Waters N.C.;  Haase S.B.
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/28
blood  cell  malaria  parasite  Plasmodium falciparum  transcriptome  animal  blood  circadian rhythm  erythrocyte  gene  gene expression  genetics  growth, development and aging  host parasite interaction  life cycle stage  malaria falciparum  mouse  parasitology  physiology  Plasmodium falciparum  Animals  Circadian Clocks  Erythrocytes  Gene Expression  Genes, Protozoan  Host-Parasite Interactions  Life Cycle Stages  Malaria, Falciparum  Mice  Plasmodium falciparum  Transcriptome