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期刊论文 [10]
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2020 [10]
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英语 [10]
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Science [10]
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T cells with dysfunctional mitochondria induce multimorbidity and premature senescence
期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:
Desdín-Micó G.
;
Soto-Heredero G.
;
Aranda J.F.
;
Oller J.
;
Carrasco E.
;
Gabandé-Rodríguez E.
;
Blanco E.M.
;
Alfranca A.
;
Cussó L.
;
Desco M.
;
Ibañez B.
;
Gortazar A.R.
;
Fernández-Marcos P.
;
Navarro M.N.
;
Hernaez B.
;
Alcamí A.
;
Baixauli F.
;
Mittelbrunn M.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
cardiovascular disease
enzyme activity
gene expression
metabolism
mitochondrial DNA
morbidity
senescence
tumor
Mus
DNA binding protein
mitochondrial protein
mitochondrial transcription factor A
nicotinamide adenine dinucleotide
transcription factor
tumor necrosis factor
animal
cytokine release syndrome
female
fitness
gene deletion
genetics
immunology
inflammation
longevity
male
metabolism
mitochondrion
mouse
multiple chronic conditions
mutant mouse strain
premature aging
T lymphocyte
ultrastructure
Aging, Premature
Animals
Cytokine Release Syndrome
DNA-Binding Proteins
Female
Gene Deletion
Inflammation
Longevity
Male
Mice
Mice, Mutant Strains
Mitochondria
Mitochondrial Proteins
Multimorbidity
NAD
Physical Fitness
T-Lymphocytes
Transcription Factors
Tumor Necrosis Factor-alpha
Widespread receptor-driven modulation in peripheral olfactory coding
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Xu L.
;
Li W.
;
Voleti V.
;
Zou D.-J.
;
Hillman E.M.C.
;
Firestein S.
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/28
antagonism
cell component
detection method
odor
olfaction
protein
animal cell
animal experiment
article
excitation
high throughput analysis
male
microscopy
mouse
nonhuman
odor
olfactory epithelium
olfactory receptor neuron
animal
confocal microscopy
innervation
mutant mouse strain
olfactory mucosa
physiology
single cell analysis
acetophenone
acetophenone derivative
benzyl acetate
benzyl derivative
citral
fragrance
Acetophenones
Acyclic Monoterpenes
Animals
Benzyl Compounds
Mice
Mice, Mutant Strains
Microscopy, Confocal
Odorants
Olfactory Mucosa
Olfactory Receptor Neurons
Single-Cell Analysis
Smell
Dendritic cell-derived hepcidin sequesters iron from the microbiota to promote mucosal healing
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Bessman N.J.
;
Mathieu J.R.R.
;
Renassia C.
;
Zhou L.
;
Fung T.C.
;
Fernandez K.C.
;
Austin C.
;
Moeller J.B.
;
Zumerle S.
;
Louis S.
;
Vaulont S.
;
Ajami N.J.
;
Sokol H.
;
Putzel G.G.
;
Arvedson T.
;
Sockolow R.E.
;
Lakhal-Littleton S.
;
Cloonan S.M.
;
Arora M.
;
Peyssonnaux C.
;
Sonnenberg G.F.
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/28
ferroportin
hepcidin
iron
cation transport protein
Hamp protein, mouse
hepcidin
iron
metal transporting protein 1
cell
digestive system disorder
immunity
iron
microorganism
animal cell
animal experiment
animal model
animal tissue
Article
controlled study
dendritic cell
enteritis
healing
immunity
intestine flora
intestine injury
iron blood level
iron homeostasis
iron metabolism
iron sequestration
mouse
mucosal healing
mucosal immunity
nonhuman
nutritional immunity
phagocyte
priority journal
protein expression
tissue regeneration
tissue repair
animal
dendritic cell
enteropathy
fecal microbiota transplantation
gene deletion
genetics
homeostasis
intestine mucosa
metabolism
microbiology
mutant mouse strain
physiology
Mus
Animals
Cation Transport Proteins
Dendritic Cells
Fecal Microbiota Transplantation
Gastrointestinal Microbiome
Gene Deletion
Hepcidins
Homeostasis
Intestinal Diseases
Intestinal Mucosa
Iron
Mice
Mice, Mutant Strains
Phagocytes
A noncanonical inhibitory circuit dampens behavioral sensitivity to light
期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:
Sonoda T.
;
Li J.Y.
;
Hayes N.W.
;
Chan J.C.
;
Okabe Y.
;
Belin S.
;
Nawabi H.
;
Schmidt T.M.
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/28
4 aminobutyric acid
cre recombinase
glutamic acid
melanopsin
neurotransmitter
4 aminobutyric acid
4 aminobutyric acid receptor
glutamate decarboxylase
glutamate decarboxylase 2
melanopsin
scotopsin
brain
hormone
inhibition
light effect
nanotechnology
sensitivity analysis
Adeno associated virus
animal cell
Article
axon
brain region
GABAergic system
immunohistochemistry
lateral geniculate body
light
mouse
nonhuman
postsynaptic potential
priority journal
pupil reflex
retina ganglion cell
superior colliculus
suprachiasmatic nucleus
vision
wild type
animal
drug effect
female
light
male
metabolism
mutant mouse strain
nerve tract
physiology
radiation response
retina ganglion cell
vision
Mus
Animals
Female
GABAergic Neurons
gamma-Aminobutyric Acid
Glutamate Decarboxylase
Light
Male
Mice
Mice, Mutant Strains
Neural Pathways
Reflex, Pupillary
Retinal Ganglion Cells
Rod Opsins
Unconscious, Psychology
Visual Perception
Effect of tolerance on the evolution of antibiotic resistance under drug combinations
期刊论文
, 2020, 卷号: 367, 期号: 6474
作者:
Liu J.
;
Gefen O.
;
Ronin I.
;
Bar-Meir M.
;
Balaban N.Q.
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/28
daptomycin
rifampicin
vancomycin
antiinfective agent
beta' subunit of RNA polymerase
daptomycin
DNA directed RNA polymerase
rifampicin
vancomycin
antibiotic resistance
bacterium
emergence
evolutionary biology
experimental study
laboratory method
survival
adult
antibiotic resistance
Article
bacterial mutation
bacterial strain
bacterium isolation
clinical article
colony forming unit
combination drug therapy
drug effect
drug tolerance
human
in vitro study
minimum inhibitory concentration
nonhuman
phylogeny
priority journal
Staphylococcus aureus
whole genome sequencing
antibiotic resistance
combination drug therapy
drug effect
genetics
methicillin resistant Staphylococcus aureus
microbial sensitivity test
microbiology
molecular evolution
mutation
single nucleotide polymorphism
Staphylococcus infection
Staphylococcus aureus
Anti-Bacterial Agents
Daptomycin
DNA-Directed RNA Polymerases
Drug Resistance, Microbial
Drug Therapy, Combination
Evolution, Molecular
Humans
Methicillin-Resistant Staphylococcus aureus
Microbial Sensitivity Tests
Mutation
Polymorphism, Single Nucleotide
Rifampin
Staphylococcal Infections
Vancomycin
Extreme tensile strain states in La0.7Ca0.3MnO3 membranes
期刊论文
, 2020, 卷号: 368, 期号: 6486
作者:
Hong S.S.
;
Gu M.
;
Verma M.
;
Harbola V.
;
Wang B.Y.
;
Lu D.
;
Vailionis A.
;
Hikita Y.
;
Pentcheva R.
;
Rondinelli J.M.
;
Hwang H.Y.
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/28
calcium oxide
ferromagnetic material
lanthanum oxide
manganese oxide
electron
inorganic compound
magnetic field
membrane
Article
calculation
controlled study
electron
magnetic field
physical parameters
priority journal
tensile strain
The malaria parasite has an intrinsic clock
期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:
Rijo-Ferreira F.
;
Acosta-Rodriguez V.A.
;
Abel J.H.
;
Kornblum I.
;
Bento I.
;
Kilaru G.
;
Klerman E.B.
;
Mota M.M.
;
Takahashi J.S.
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/28
cell
circadian rhythm
food intake
malaria
Mus
Plasmodium chabaudi
transcription factor CLOCK
animal
association
circadian rhythm
darkness
eating
erythrocyte
feeding behavior
fever
gene expression regulation
genetic transcription
genetics
host parasite interaction
malaria
mouse
mutant mouse strain
parasitology
pathophysiology
physiology
Plasmodium chabaudi
Animals
Circadian Rhythm
CLOCK Proteins
Cues
Darkness
Eating
Erythrocytes
Feeding Behavior
Fever
Gene Expression Regulation
Host-Parasite Interactions
Malaria
Mice
Mice, Mutant Strains
Plasmodium chabaudi
Transcription, Genetic
Making ultrastrong steel tough by grain-boundary delamination
期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:
Liu L.
;
Yu Q.
;
Wang Z.
;
Ell J.
;
Huang M.X.
;
Ritchie R.O.
收藏
  |  
浏览/下载:117/0
  |  
提交时间:2020/07/28
cracking (fracture)
delamination
ductile deformation
grain boundary
plasticity
steel
strain
transformation
Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex
期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:
[无可用作者姓名]
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/28
Hrd1 ubiquitin ligase complex
Hrd3 protein
membrane protein
polypeptide
rhomboid like Der1 protein
ubiquitin protein ligase
unclassified drug
Yos9 protein
biodegradation
cell component
electron microscopy
enzyme
molecular analysis
protein
ultrastructure
Article
binding site
carboxy terminal sequence
controlled study
cryoelectron microscopy
cytosol
endoplasmic reticulum
enzyme substrate
enzyme substrate complex
fungal strain
glycosylation
micelle
molecular dynamics
priority journal
protein cross linking
protein degradation
protein function
protein misfolding
protein structure
yeast
Dermal sheath contraction powers stem cell niche relocation during hair cycle regression
期刊论文
, 2020, 卷号: 367, 期号: 6474
作者:
Heitman N.
;
Sennett R.
;
Mok K.-W.
;
Saxena N.
;
Srivastava D.
;
Martino P.
;
Grisanti L.
;
Wang Z.
;
Ma'ayan A.
;
Rompolas P.
;
Rendl M.
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/28
aggrecan
calcium
calmodulin
myosin light chain kinase
cell component
enzyme
enzyme activity
growth
hair
homeostasis
muscle
skin
animal cell
animal tissue
Article
controlled study
cutaneous parameters
dermal sheath contraction
hair cycle regression
hair follicle
hair root
in vivo study
mouse
nonhuman
priority journal
protein expression
skin fibroblast
smooth muscle contractility
stem cell niche
animal
dermis
genetics
human
muscle contraction
mutant mouse strain
physiology
regeneration
smooth muscle
stem cell niche
Aggrecans
Animals
Dermis
Hair Follicle
Humans
Mice
Mice, Mutant Strains
Muscle Contraction
Muscle, Smooth
Regeneration
Stem Cell Niche