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Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat 期刊论文
, 2020, 卷号: 368, 期号: 6493
作者:  Wang H.;  Sun S.;  Ge W.;  Zhao L.;  Hou B.;  Wang K.;  Lyu Z.;  Chen L.;  Xu S.;  Guo J.;  Li M.;  Su P.;  Li X.;  Wang G.;  Bo C.;  Fang X.;  Zhuang W.;  Cheng X.;  Wu J.;  Dong L.;  Chen W.;  Li W.;  Xiao G.;  Zhao J.;  Hao Y.;  Xu Y.;  Gao Y.;  Liu W.;  Liu Y.;  Yin H.;  Li J.;  Li X.;  Zhao Y.;  Wang X.;  Ni F.;  Ma X.;  Li A.;  Xu S.S.;  Bai G.;  Nevo E.;  Gao C.;  Ohm H.;  Kong L.
收藏  |  浏览/下载:47/0  |  提交时间:2020/07/28
fungus  gene transfer  genome  germplasm  toxin  wheat  Fungi  Fusarium  Lophopyrum elongatum  Triticum aestivum  glutathione transferase  disease resistance  Epichloe  Fusarium  genetics  horizontal gene transfer  microbiology  molecular cloning  pathogenicity  plant breeding  plant disease  Poaceae  wheat  Cloning, Molecular  Disease Resistance  Epichloe  Fusarium  Gene Transfer, Horizontal  Glutathione Transferase  Plant Breeding  Plant Diseases  Poaceae  Triticum  
Na+-gated water-conducting nanochannels for boosting CO2 conversion to liquid fuels 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Li H.;  Qiu C.;  Ren S.;  Dong Q.;  Zhang S.;  Zhou F.;  Liang X.;  Wang J.;  Li S.;  Yu M.
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/28
aluminum  carbon dioxide  carbon monoxide  copper  fuel  hydrogen  methanol  nanochannel  sodium ion  water  zeolite  zinc  carbon dioxide  high temperature  hydraulic conductivity  membrane  nanocomposite  nanotechnology  separation  sodium  thermodynamics  adsorption  Article  Brunauer Emmett Teller  catalyst  chemical composition  controlled study  crystal  density functional theory  energy dispersive X ray spectroscopy  gas  hydrogenation  measurement  priority journal  scanning electron microscopy  surface area  water permeability  
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Dai W.;  Zhang B.;  Jiang X.-M.;  Su H.;  Li J.;  Zhao Y.;  Xie X.;  Jin Z.;  Peng J.;  Liu F.;  Li C.;  Li Y.;  Bai F.;  Wang H.;  Cheng X.;  Cen X.;  Hu S.;  Yang X.;  Wang J.;  Liu X.;  Xiao G.;  Jiang H.;  Rao Z.;  Zhang L.-K.;  Xu Y.;  Yang H.;  Liu H.
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28
aldehyde  antimicrobial activity  drug  enzyme activity  infectivity  inhibitor  reaction kinetics  viral disease  Coronavirus  SARS coronavirus  3C-like proteinase, Coronavirus  antivirus agent  cysteine proteinase  viral protein  animal  Betacoronavirus  chemical structure  chemistry  Chlorocebus aethiops  Coronavirus infection  dog  drug design  drug effect  enzyme active site  enzymology  female  human  male  mouse  pandemic  preclinical study  protein tertiary structure  Sprague Dawley rat  toxicity testing  Vero cell line  virus pneumonia  Animals  Antiviral Agents  Betacoronavirus  Catalytic Domain  Chlorocebus aethiops  Coronavirus Infections  Cysteine Endopeptidases  Dogs  Drug Design  Drug Evaluation, Preclinical  Female  Humans  Male  Mice  Molecular Structure  Pandemics  Pneumonia, Viral  Protein Structure, Tertiary  Rats, Sprague-Dawley  Toxicity Tests  Vero Cells  Viral Nonstructural Proteins  
Structure of the RNA-dependent RNA polymerase from COVID-19 virus 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Gao Y.;  Yan L.;  Huang Y.;  Liu F.;  Zhao Y.;  Cao L.;  Wang T.;  Sun Q.;  Ming Z.;  Zhang L.;  Ge J.;  Zheng L.;  Zhang Y.;  Wang H.;  Zhu Y.;  Zhu C.;  Hu T.;  Hua T.;  Zhang B.;  Yang X.;  Li J.;  Yang H.;  Liu Z.;  Xu W.;  Guddat L.W.;  Wang Q.;  Lou Z.;  Rao Z.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
comparative study  drug  electron microscopy  enzyme  enzyme activity  RNA  virus  Coronavirus  SARS coronavirus  adenosine phosphate  alanine  antivirus agent  NSP7 protein, SARS-CoV-2  NSP8 protein, SARS-CoV-2  remdesivir  RNA directed RNA polymerase  RNA-dependent RNA polymerase, coronavirus  viral protein  beta sheet  Betacoronavirus  chemistry  cryoelectron microscopy  drug design  enzyme active site  enzymology  metabolism  molecular model  protein domain  ultrastructure  Adenosine Monophosphate  Alanine  Antiviral Agents  Betacoronavirus  Catalytic Domain  Cryoelectron Microscopy  Drug Design  Models, Molecular  Protein Conformation, beta-Strand  Protein Domains  RNA Replicase  Viral Nonstructural Proteins  
Helical quantum Hall phase in graphene on SrTiO3 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:  Veyrat L.;  Déprez C.;  Coissard A.;  Li X.;  Gay F.;  Watanabe K.;  Taniguchi T.;  Han Z.;  Piot B.A.;  Sellier H.;  Sacépé B.
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/28
graphene  metal oxide  strontium titanate  unclassified drug  experimental study  magnetic field  temperature effect  topology  Article  controlled study  dielectric constant  magnetic field  prediction  priority journal  quantum mechanics  temperature  
De novo protein design enables the precise induction of RSV-neutralizing antibodies 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Sesterhenn F.;  Yang C.;  Bonet J.;  Cramer J.T.;  Wen X.;  Wang Y.;  Chiang C.-I.;  Abriata L.A.;  Kucharska I.;  Castoro G.;  Vollers S.S.;  Galloux M.;  Dheilly E.;  Rosset S.;  Corthésy P.;  Georgeon S.;  Villard M.;  Richard C.-A.;  Descamps D.;  Delgado T.;  Oricchio E.;  Rameix-Welti M.-A.;  Más V.;  Ervin S.;  Eléouët J.-F.;  Riffault S.;  Bates J.T.;  Julien J.-P.;  Li Y.;  Jardetzky T.;  Krey T.;  Correia B.E.
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/28
algorithm  antibody  design  neutralization  protein  vaccine  Mus  Primates  Respiratory syncytial virus  Rice stripe virus  epitope  fusion protein  nanobody  neutralizing antibody  respiratory syncytial virus vaccine  biology  biosynthesis  chemistry  human  Human respiratory syncytial virus  immunology  procedures  protein conformation  protein engineering  protein motif  Amino Acid Motifs  Antibodies, Neutralizing  Computational Biology  Humans  Immunodominant Epitopes  Protein Conformation  Protein Engineering  Recombinant Fusion Proteins  Respiratory Syncytial Virus Vaccines  Respiratory Syncytial Virus, Human  Single-Domain Antibodies  
Balancing volumetric and gravimetric uptake in highly porous materials for clean energy 期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:  Chen Z.;  Li P.;  Anderson R.;  Wang X.;  Zhang X.;  Robison L.;  Redfern L.R.;  Moribe S.;  Islamoglu T.;  Gómez-Gualdrón D.A.;  Yildirim T.;  Stoddart J.F.;  Farha O.K.
收藏  |  浏览/下载:29/0  |  提交时间:2020/07/28
aluminum  hydrogen  iron  metal organic framework  methane  adsorption  gravimetry  organometallic compound  porous medium  volume  adsorption  alternative energy  Article  environmental temperature  gravimetry  porosity  pressure  priority journal  simulation  surface area  synthesis  United States  volumetry  
Ultrahigh thermal conductivity in isotope-enriched cubic boron nitride 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者:  Chen K.;  Song B.;  Ravichandran N.K.;  Zheng Q.;  Chen X.;  Lee H.;  Sun H.;  Li S.;  Gamage G.A.G.U.;  Tian F.;  Ding Z.;  Song Q.;  Rai A.;  Wu H.;  Koirala P.;  Schmidt A.J.;  Watanabe K.;  Lv B.;  Ren Z.;  Shi L.;  Cahill D.G.;  Taniguchi T.;  Broido D.;  Chen G.
收藏  |  浏览/下载:95/0  |  提交时间:2020/07/28
boron arsenide  boron derivative  boron phosphide  cubic boron nitride  isotope  unclassified drug  concentration (composition)  inorganic compound  temperature effect  thermal conductivity  Article  phonon  priority journal  thermal conductivity  ultrahigh thermal conductivity  
A precise polyrotaxane synthesizer 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Qiu Y.;  Song B.;  Pezzato C.;  Shen D.;  Liu W.;  Zhang L.;  Feng Y.;  Guo Q.-H.;  Cai K.;  Li W.;  Chen H.;  Nguyen M.T.;  Shi Y.;  Cheng C.;  Dean Astumian R.;  Li X.;  Fraser Stoddart J.
收藏  |  浏览/下载:41/0  |  提交时间:2020/07/28
Very fast CRISPR on demand 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Liu Y.;  Zou R.S.;  He S.;  Nihongaki Y.;  Li X.;  Razavi S.;  Wu B.;  Ha T.
收藏  |  浏览/下载:20/0  |  提交时间:2020/07/28
Cas9 endonuclease Streptococcus pyogenes  double strand break repair protein MRE11  H2AX protein, human  histone  MRE11 protein, human  CRISPR Cas system  DNA cleavage  DNA repair  double stranded DNA break  fluorescence imaging  gene editing  genetics  HEK293 cell line  human  light  metabolism  phosphorylation  procedures  radiation response  single cell analysis  CRISPR-Associated Protein 9  CRISPR-Cas Systems  DNA Breaks, Double-Stranded  DNA Cleavage  DNA Repair  Gene Editing  HEK293 Cells  Histones  Humans  Light  MRE11 Homologue Protein  Optical Imaging  Phosphorylation  Single-Cell Analysis