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Pathological damage, immune-related protein expression, and oxidative stress in lungs of BALB/c mice induced by haze PM2.5 biological components exposure 期刊论文
ATMOSPHERIC ENVIRONMENT, 2020, 卷号: 223
作者:  Wu B.;  Dong Y.;  Wang M.;  Yang W.;  Hu L.;  Zhou D.;  Lv J.;  Chai T.
收藏  |  浏览/下载:21/0  |  提交时间:2022/01/18
Apoptosis  Haze  Immune related protein  Oxidative stress  Pathological pulmonary damage  PM2.5  
Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques 期刊论文
Science, 2020, 卷号: 369, 期号: 6505
作者:  Deng W.;  Bao L.;  Liu J.;  Xiao C.;  Liu J.;  Xue J.;  Lv Q.;  Qi F.;  Gao H.;  Yu P.;  Xu Y.;  Qu Y.;  Li F.;  Xiang Z.;  Yu H.;  Gong S.;  Liu M.;  Wang G.;  Wang S.;  Song Z.;  Liu Y.;  Zhao W.;  Han Y.;  Zhao L.;  Liu X.;  Wei Q.;  Qin C.
收藏  |  浏览/下载:99/0  |  提交时间:2022/01/14
COVID-19 in Africa: Dampening the storm? 期刊论文
Science, 2020, 卷号: 369, 期号: 6504
作者:  Mbow M.;  Lell B.;  Jochems S.P.;  Cisse B.;  Mboup S.;  Dewals B.G.;  Jaye A.;  Dieye A.;  Yazdanbakhsh M.
收藏  |  浏览/下载:26/0  |  提交时间:2022/01/14
Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications 期刊论文
Science, 2020, 卷号: 369, 期号: 6508
作者:  Mathew D.;  Giles J.R.;  Baxter A.E.;  Oldridge D.A.;  Greenplate A.R.;  Wu J.E.;  Alanio C.;  Kuri-Cervantes H.;  Pampena M.B.;  D'Andrea K.;  Manne S.;  Chen Z.;  Huang Y.J.;  Reilly J.P.;  Weisman A.R.;  Ittner C.A.G.;  Kuthuru O.;  Dougherty J.;  Nzingha K.;  Han N.;  Kim J.;  Pattekar A.;  Goodwin E.C.;  Anderson E.M.;  Weirick M.E.;  Gouma S.;  Arevalo C.P.;  Bolton M.J.;  Chen F.;  Lacey S.F.;  Ramage H.;  Cherry S.;  Hensley S.E.;  Apostolidis S.A.;  Huang A.C.;  Vella L.A.;  Betts M.R.;  Meyer N.J.;  Wherry E.J.;  Alam Z.;  Addison M.M.;  Byrne K.T.;  Chandra A.;  Descamps H.C.;  Kaminskiy Y.;  Hamilton J.T.;  Noll J.H.;  Omran D.K.;  Perkey E.;  Prager E.M.;  Pueschl D.;  Shah J.B.;  Shilan J.S.;  Vanderbeck A.N.;  UPenn COVID Processing Unit
收藏  |  浏览/下载:21/0  |  提交时间:2022/01/14
Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection 期刊论文
Science, 2020, 卷号: 370, 期号: 6513
作者:  Habibi M.S.;  Thwaites R.S.;  Chang M.;  Jozwik A.;  Paras A.;  Kirsebom F.;  Varese A.;  Owen A.;  Cuthbertson L.;  James P.;  Tunstall T.;  Nickle D.;  Hansel T.T.;  Moffatt M.F.;  Johansson C.;  Chiu C.;  Openshaw P.J.M.
收藏  |  浏览/下载:24/0  |  提交时间:2022/01/14
T cells with dysfunctional mitochondria induce multimorbidity and premature senescence 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Desdín-Micó G.;  Soto-Heredero G.;  Aranda J.F.;  Oller J.;  Carrasco E.;  Gabandé-Rodríguez E.;  Blanco E.M.;  Alfranca A.;  Cussó L.;  Desco M.;  Ibañez B.;  Gortazar A.R.;  Fernández-Marcos P.;  Navarro M.N.;  Hernaez B.;  Alcamí A.;  Baixauli F.;  Mittelbrunn M.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
cardiovascular disease  enzyme activity  gene expression  metabolism  mitochondrial DNA  morbidity  senescence  tumor  Mus  DNA binding protein  mitochondrial protein  mitochondrial transcription factor A  nicotinamide adenine dinucleotide  transcription factor  tumor necrosis factor  animal  cytokine release syndrome  female  fitness  gene deletion  genetics  immunology  inflammation  longevity  male  metabolism  mitochondrion  mouse  multiple chronic conditions  mutant mouse strain  premature aging  T lymphocyte  ultrastructure  Aging, Premature  Animals  Cytokine Release Syndrome  DNA-Binding Proteins  Female  Gene Deletion  Inflammation  Longevity  Male  Mice  Mice, Mutant Strains  Mitochondria  Mitochondrial Proteins  Multimorbidity  NAD  Physical Fitness  T-Lymphocytes  Transcription Factors  Tumor Necrosis Factor-alpha  
Microenvironment mapping via Dexter energy transfer on immune cells 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Geri J.B.;  Oakley J.V.;  Reyes-Robles T.;  Wang T.;  McCarver S.J.;  White C.H.;  Rodriguez-Rivera F.P.;  Parker D.L.;  Hett E.C.;  Fadeyi O.O.;  Oslund R.C.;  MacMillan D.W.C.
收藏  |  浏览/下载:33/0  |  提交时间:2020/07/28
antibody conjugate  carbene  programmed death 1 ligand 1  methane  programmed death 1 ligand 1  antibody  catalysis  catalyst  cell component  detection method  enzyme  enzyme activity  protein  antigen binding  Article  cell membrane  energy transfer  human  immunocompetent cell  immunological synapse  lymphocyte  photocatalysis  priority journal  protein analysis  protein protein interaction  tumor microenvironment  catalysis  chemistry  energy transfer  Jurkat cell line  metabolism  photochemistry  procedures  radiation response  ultraviolet radiation  B7-H1 Antigen  Catalysis  Cell Membrane  Cellular Microenvironment  Energy Transfer  Humans  Jurkat Cells  Lymphocytes  Methane  Photochemical Processes  Protein Interaction Mapping  Protein Interaction Maps  Ultraviolet Rays  
HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease 期刊论文
, 2020, 卷号: 369, 期号: 6500
作者:  Cook S.A.;  Comrie W.A.;  Poli M.C.;  Similuk M.;  Oler A.J.;  Faruqi A.J.;  Kuhns D.B.;  Yang S.;  Vargas-Hernández A.;  Carisey A.F.;  Fournier B.;  Anderson D.E.;  Price S.;  Smelkinson M.;  Abou Chahla W.;  Forbes L.R.;  Mace E.M.;  Cao T.N.;  Coban-Akdemir Z.H.;  Jhangiani S.N.;  Muzny D.M.;  Gibbs R.A.;  Lupski J.R.;  Orange J.S.;  Cuvelier G.D.E.;  Al Hassani M.;  Al Kaabi N.;  Al Yafei Z.;  Jyonouchi S.;  Raje N.;  Caldwell J.W.;  Huang Y.;  Burkhardt J.K.;  Latour S.;  Chen B.;  ElGhazali G.;  Rao V.K.;  Chinn I.K.;  Lenardo M.J.
收藏  |  浏览/下载:39/0  |  提交时间:2020/07/28
actin  adenosine diphosphate ribosylation factor 1  ARF1 protein, human  cytokine  mammalian target of rapamycin complex 2  membrane protein  NCKAP1L protein, human  WASF1 protein, human  WASF2 protein, human  WASF3 protein, human  Wiskott Aldrich syndrome protein  biosynthesis  CD4+ T lymphocyte  cell proliferation  chemistry  genetics  human  immune deficiency  immunology  lymphoproliferative disease  metabolism  pedigree  phosphorylation  physiology  Actins  ADP-Ribosylation Factor 1  CD4-Positive T-Lymphocytes  Cell Proliferation  Cytokines  Humans  Immunologic Deficiency Syndromes  Lymphoproliferative Disorders  Mechanistic Target of Rapamycin Complex 2  Membrane Proteins  Pedigree  Phosphorylation  Wiskott-Aldrich Syndrome Protein Family  
Poised for tissue repair 期刊论文
, 2020, 卷号: 369, 期号: 6500
作者:  Harrison O.
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/28
CD8+ T lymphocyte  human  immune system  immunology  microbiology  microflora  skin  Staphylococcus epidermidis  symbiosis  wound healing  CD8-Positive T-Lymphocytes  Humans  Immune System  Microbiota  Skin  Staphylococcus epidermidis  Symbiosis  Wound Healing  
Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Zhou Z.;  He H.;  Wang K.;  Shi X.;  Wang Y.;  Su Y.;  Wang Y.;  Li D.;  Liu W.;  Zhang Y.;  Shen L.;  Han W.;  Shen L.;  Ding J.;  Shao F.
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/28
cell  cell component  cytology  enzyme  enzyme activity  gene expression  immunity  tumor  Mus  gamma interferon  granzyme  GSDMB protein, human  GZMA protein, human  pore forming cytotoxic protein  tumor protein  animal  Bagg albino mouse  chemistry  cytotoxic T lymphocyte  enzymology  genetics  HEK293 cell line  human  immunology  metabolism  mouse  natural killer cell  neoplasm  pathology  protein degradation  protein domain  pyroptosis  transgenic mouse  Animals  Granzymes  HEK293 Cells  Humans  Interferon-gamma  Killer Cells, Natural  Mice  Mice, Inbred BALB C  Mice, Transgenic  Neoplasm Proteins  Neoplasms  Pore Forming Cytotoxic Proteins  Protein Domains  Proteolysis  Pyroptosis  T-Lymphocytes, Cytotoxic