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Delivery of mRNA vaccine with a lipid-like material potentiates antitumor efficacy through toll-like receptor 4 signaling 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 6
作者:  Zhang H.;  You X.;  Wang X.;  Cui L.;  Wang Z.;  Xu F.;  Li M.;  Yang Z.;  Liu J.;  Huang P.;  Kang Y.;  Wu J.;  Xia X.
收藏  |  浏览/下载:41/0  |  提交时间:2021/05/24
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文
, 2020, 卷号: 368, 期号: 6498
作者:  Yin W.;  Mao C.;  Luan X.;  Shen D.-D.;  Shen Q.;  Su H.;  Wang X.;  Zhou F.;  Zhao W.;  Gao M.;  Chang S.;  Xie Y.-C.;  Tian G.;  Jiang H.-W.;  Tao S.-C.;  Shen J.;  Jiang Y.;  Jiang H.;  Xu Y.;  Zhang S.;  Zhang Y.;  Xu H.E.
收藏  |  浏览/下载:107/0  |  提交时间:2020/07/28
adenosine phosphate  alanine  antivirus agent  enzyme inhibitor  multiprotein complex  NSP7 protein, SARS-CoV-2  NSP8 protein, SARS-CoV-2  remdesivir  RNA directed RNA polymerase  RNA-dependent RNA polymerase, coronavirus  viral protein  virus RNA  Betacoronavirus  chemistry  cryoelectron microscopy  drug effect  enzyme active site  enzymology  metabolism  molecular model  physiology  protein conformation  virus replication  Adenosine Monophosphate  Alanine  Antiviral Agents  Betacoronavirus  Catalytic Domain  Cryoelectron Microscopy  Enzyme Inhibitors  Models, Molecular  Multiprotein Complexes  Protein Conformation  RNA Replicase  RNA, Viral  Viral Nonstructural Proteins  Virus Replication  
Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Liu J.;  Kim Y.S.;  Richardson C.E.;  Tom A.;  Ramakrishnan C.;  Birey F.;  Katsumata T.;  Chen S.;  Wang C.;  Wang X.;  Joubert L.-M.;  Jiang Y.;  Wang H.;  Fenno L.E.;  Tok J.B.-H.;  Paşca S.P.;  Shen K.;  Bao Z.;  Deisseroth K.
收藏  |  浏览/下载:38/0  |  提交时间:2020/07/28
poly(3,4 ethylenedioxythiophene)  polyaniline  polymer  unclassified drug  3-nitro-o-phenylenediamine  aniline  aniline derivative  ascorbate peroxidase  nitro derivative  phenylenediamine derivative  polymer  anatomy  genetic engineering  membrane  physiological response  polymer  animal cell  Article  biocompatibility  brain nerve cell  brain slice  Caenorhabditis elegans  cell membrane  cell viability  controlled study  genetic procedures  genetically targeted chemical assemby  hippocampal neuronal culture  human  human cell  in vivo study  nerve cell membrane  nonhuman  polymerization  priority journal  rat  synthesis  action potential  animal  cell culture  cell survival  chemistry  electric conductivity  enzymology  genetic engineering  genetic transduction  genetics  HEK293 cell line  hippocampus  membrane potential  metabolism  motoneuron  mouse  muscle cell  nerve cell  patch clamp technique  physiology  Animalia  Action Potentials  Aniline Compounds  Animals  Ascorbate Peroxidases  Caenorhabditis elegans  Cell Membrane  Cell Survival  Cells, Cultured  Electric Conductivity  Genetic Engineering  HEK293 Cells  Hippocampus  Humans  Membrane Potentials  Mice  Motor Neurons  Muscle Cells  Neurons  Nitro Compounds  Patch-Clamp Techniques  Phenylenediamines  Polymers  Rats  Transduction, Genetic  
Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond 期刊论文
Science, 2017, 卷号: 355, 期号: 6329
作者:  Mitchell L.A.;  Wang A.;  Stracquadanio G.;  Kuang Z.;  Wang X.;  Yang K.;  Richardson S.;  Martin J.A.;  Zhao Y.;  Walker R.;  Luo Y.;  Dai H.;  Dong K.;  Tang Z.;  Yang Y.;  Cai Y.;  Heguy A.;  Ueberheide B.;  Fenyö D.;  Dai J.;  Bader J.S.;  Boeke J.D.
收藏  |  浏览/下载:15/0  |  提交时间:2022/01/14