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Polypeptide nanoformulation-induced immunogenic cell death and remission of immunosuppression for enhanced chemoimmunotherapy 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 4
作者:  Feng X.;  Xu W.;  Liu J.;  Li D.;  Li G.;  Ding J.;  Chen X.
收藏  |  浏览/下载：33/0  |  提交时间：2021/09/01
Chemoimmunotherapy  Controlled drug release  Immunogenic cell death  Polypeptide nanogel  Remission of Immunosuppression  
A monocot-specific hydroxycinnamoylputrescine gene cluster contributes to immunity and cell death in rice 期刊论文
Science Bulletin, 2021
作者:  Fang H.;  Shen S.;  Wang D.;  Zhang F.;  Zhang C.;  Wang Z.;  Zhou Q.;  Wang R.;  Tao H.;  He F.;  Yang C.;  Peng M.;  Jing X.;  Hao Z.;  Liu X.;  Luo J.;  Wang G.-L.;  Ning Y.
收藏  |  浏览/下载：37/0  |  提交时间：2021/09/01
bZIP transcription factor  Cell death  HP gene cluster  Magnaporthe oryzae  Oryza sativa  Plant immunity  Secondary metabolites  
N-salicyloyl tryptamine derivatives as potential therapeutic agents for Alzheimer's disease with neuroprotective effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115
作者:  Bai, Yinliang;  Liu, Dan;  Zhang, Honghua;  Wang, Yuying;  Wang, Degui;  Cai, Hongbin;  Wen, Huaixiu;  Yuan, Guoqiang;  An, Hui;  Wang, Yali;  Shi, Tao;  Wang, Zhen
收藏  |  浏览/下载：45/0  |  提交时间：2022/04/28
CELL-DEATH  INFLAMMASOME  PYROPTOSIS  NEUROINFLAMMATION  MICROGLIA  MECHANISM  APOPTOSIS  
CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation 期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:  Muendlein H.I.;  Jetton D.;  Connolly W.M.;  Eidell K.P.;  Magri Z.;  Smirnova I.;  Poltorak A.
收藏  |  浏览/下载：49/0  |  提交时间：2020/07/28
FLICE inhibitory protein  interleukin 1beta  lipopolysaccharide  messenger RNA  succinate dehydrogenase (ubiquinone)  Casp1 protein, mouse  caspase 8  Cflar protein, mouse  cryopyrin  FLICE inhibitory protein  IL1B protein, mouse  inflammasome  interleukin 1beta  interleukin 1beta converting enzyme  lipopolysaccharide  succinate dehydrogenase (ubiquinone)  cell  enzyme activity  inhibition  maturation  protein  animal cell  animal experiment  Article  bone marrow derived macrophage  cell death  cell protection  complex formation  controlled study  cytokine release  in vitro study  inflammation  mouse  nonhuman  priority journal  protein analysis  protein degradation  protein function  protein interaction  pyroptosis  animal  gene knockdown  genetics  immunology  macrophage  macrophage activation  metabolism  physiology  Murinae  Animals  CASP8 and FADD-Like Apoptosis Regulating Protein  Caspase 1  Caspase 8  Electron Transport Complex II  Gene Knockdown Techniques  Inflammasomes  Interleukin-1beta  Lipopolysaccharides  Macrophage Activation  Macrophages  Mice  NLR Family, Pyrin Domain-Containing 3 Protein  Pyroptosis  
Microenvironment mapping via Dexter energy transfer on immune cells 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Geri J.B.;  Oakley J.V.;  Reyes-Robles T.;  Wang T.;  McCarver S.J.;  White C.H.;  Rodriguez-Rivera F.P.;  Parker D.L.;  Hett E.C.;  Fadeyi O.O.;  Oslund R.C.;  MacMillan D.W.C.
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/28
antibody conjugate  carbene  programmed death 1 ligand 1  methane  programmed death 1 ligand 1  antibody  catalysis  catalyst  cell component  detection method  enzyme  enzyme activity  protein  antigen binding  Article  cell membrane  energy transfer  human  immunocompetent cell  immunological synapse  lymphocyte  photocatalysis  priority journal  protein analysis  protein protein interaction  tumor microenvironment  catalysis  chemistry  energy transfer  Jurkat cell line  metabolism  photochemistry  procedures  radiation response  ultraviolet radiation  B7-H1 Antigen  Catalysis  Cell Membrane  Cellular Microenvironment  Energy Transfer  Humans  Jurkat Cells  Lymphocytes  Methane  Photochemical Processes  Protein Interaction Mapping  Protein Interaction Maps  Ultraviolet Rays  
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance 期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:  ElTanbouly M.A.;  Zhao Y.;  Nowak E.;  Li J.;  Schaafsma E.;  Le Mercier I.;  Ceeraz S.;  Lines J.L.;  Peng C.;  Carriere C.;  Huang X.;  Day M.;  Koehn B.;  Lee S.W.;  Morales M.S.;  Hogquist K.A.;  Jameson S.C.;  Mueller D.;  Rothstein J.;  Blazar B.R.;  Cheng C.;  Noelle R.J.
收藏  |  浏览/下载：56/0  |  提交时间：2020/07/28
cell protein  interferon  kruppel like factor 2  T lymphocyte receptor  unclassified drug  V type immunoglobulin domain containing suppressor of T cell activation protein  B7 antigen  Dies1 protein, mouse  lymphocyte antigen receptor  membrane protein  monoclonal antibody  VSIR protein, human  biological development  cell  gene expression  heterogeneity  homeostasis  immune response  immunity  tolerance  acute graft versus host disease  animal cell  animal experiment  animal model  Article  CD4+ T lymphocyte  cell death  cell expansion  cell fate  cell heterogeneity  cell loss  cell survival  controlled study  female  gene  gene deletion  homeostasis  immunological tolerance  in vivo study  long term survival  male  mouse  nonhuman  phenotype  priority journal  protein expression  protein function  rheumatoid arthritis  RNA sequencing  systemic lupus erythematosus  T lymphocyte  T lymphocyte activation  T lymphocyte subpopulation  TCR gene  upregulation  VISTA gene  animal  C57BL mouse  genetics  immunological tolerance  immunology  knockout mouse  lymphocyte activation  physiology  T lymphocyte  Mus  Animals  Antibodies, Monoclonal  B7 Antigens  Lymphocyte Activation  Membrane Proteins  Mice  Mice, Inbred C57BL  Mice, Knockout  Peripheral Tolerance  Receptors, Antigen, T-Cell  T-Lymphocytes  
CRISPR-engineered T cells in patients with refractory cancer 期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:  Stadtmauer E.A.;  Fraietta J.A.;  Davis M.M.;  Cohen A.D.;  Weber K.L.;  Lancaster E.;  Mangan P.A.;  Kulikovskaya I.;  Gupta M.;  Chen F.;  Tian L.;  Gonzalez V.E.;  Xu J.;  Jung I.-Y.;  Joseph Melenhorst J.;  Plesa G.;  Shea J.;  Matlawski T.;  Cervini A.;  Gaymon A.L.;  Desjardins S.;  Lamontagne A.;  Salas-Mckee J.;  Fesnak A.;  Siegel D.L.;  Levine B.L.;  Jadlowsky J.K.;  Young R.M.;  Chew A.;  Hwang W.-T.;  Hexner E.O.;  Carreno B.M.;  Nobles C.L.;  Bushman F.D.;  Parker K.R.;  Qi Y.;  Satpathy A.T.;  Chang H.Y.;  Zhao Y.;  Lacey S.F.;  June C.H.
收藏  |  浏览/下载：46/0  |  提交时间：2020/07/28
heterodimer  programmed death 1 receptor  T lymphocyte receptor alpha chain  T lymphocyte receptor beta chain  cancer  cell  gene  gene expression  genetic engineering  immunity  protein  adult  aged  Article  cancer patient  cell engineering  chromosome translocation  clinical article  clustered regularly interspaced short palindromic repeat  controlled study  CRISPR-CAS9 system  feasibility study  female  gene editing  gene expression  gene frequency  gene locus  genetic code  human  human cell  male  middle aged  myeloma  PDCD1 gene  phase 1 clinical trial  priority journal  sarcoma  T lymphocyte  TRAC gene  TRBC gene  tumor immunity  
Spotted gums and hybrids: Impact of pests and diseases, ontogeny and climate on tree performance 期刊论文
, 2020, 卷号: 472
作者:  Bonora F.S.;  Hayes R.A.;  Nahrung H.F.;  Lee D.J.
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/28
Cell death  Forestry  Pathogens  Plants (botany)  Rain  Biotic and abiotic stress  Climate parameters  Climatic conditions  Commercial plantation  Diameter-at-breast heights  Environmental factors  Plant interactions  Water availability  Growth rate  climate change  climate conditions  environmental factor  environmental stress  growth rate  host-pathogen interaction  hybrid  ontogeny  pathogen  pest species  plantation  rainfall  temperature effect  timber  tree  Defoliation  Forestry  Growth Rate  Hybrids  Pathogens  Performance  Pests  Rain  Australia  Queensland  Corymbia citriodora  Corymbia henryi  Corymbia torelliana  Hexapoda  
Cysteine depletion induces pancreatic tumor ferroptosis in mice 期刊论文
, 2020, 卷号: 368, 期号: 6486
作者:  Badgley M.A.;  Kremer D.M.;  Carlo Maurer H.;  DelGiorno K.E.;  Lee H.-J.;  Purohit V.;  Sagalovskiy I.R.;  Ma A.;  Kapilian J.;  Firl C.E.M.;  Decker A.R.;  Sastra S.A.;  Palermo C.F.;  Andrade L.R.;  Sajjakulnukit P.;  Zhang L.;  Tolstyka Z.P.;  Hirschhorn T.;  Lamb C.;  Liu T.;  Gu W.;  Scott Seeley E.;  Stone E.;  Georgiou G.;  Manor U.;  Iuga A.;  Wahl G.M.;  Stockwell B.R.;  Lyssiotis C.A.;  Olive K.P.
收藏  |  浏览/下载：41/0  |  提交时间：2020/07/28
coenzyme A  cysteine  glutathione  amino acid  induced response  rodent  tumor  animal experiment  animal model  animal tissue  Article  cell death  cell survival  cell viability  controlled study  down regulation  ferroptosis  fragmentation reaction  human  human cell  lipid oxidation  lipophilicity  mouse  necroptosis  nonhuman  pancreas tumor  pancreatic ductal carcinoma cell line  priority journal  protein cleavage  protein expression  tumor growth  tumor microenvironment  tumor xenograft  Mus  
Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Rougé L.;  Chiang N.;  Steffek M.;  Kugel C.;  Croll T.I.;  Tam C.;  Estevez A.;  Arthur C.P.;  Koth C.M.;  Ciferri C.;  Kraft E.;  Payandeh J.;  Nakamura G.;  Koerber J.T.;  Rohou A.
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/28
CD20 antigen  dimer  epitope  Fc receptor  immunoglobulin F(ab) fragment  obinutuzumab  ocrelizumab  ofatumumab  rituximab  tositumomab i 131  antibody  antigen  cell  chemical binding  composite  gene expression  genetic marker  protein  amino acid sequence  antibody dependent cellular cytotoxicity  antigen antibody complex  antigen binding  antigen structure  Article  cell death  cell surface  chemical bond  complement dependent cytotoxicity  drug protein binding  drug targeting  electron microscopy  human  humoral immune deficiency  insect cell  lipid raft  malignant neoplasm  molecular recognition  multiple sclerosis  nonhuman  phagocytosis  priority journal  protein cross linking  protein interaction  stoichiometry  surface plasmon resonance