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| Rise and fall of lung cancers in relation to tobacco smoking and air pollution: A global trend analysis from 1990 to 2012 期刊论文
ATMOSPHERIC ENVIRONMENT, 2022, 卷号: 269
作者: Yim S.H.L.; Huang T.; Ho J.M.W.; Lam A.S.M.; Yau S.T.Y.; Yuen T.W.H.; Dong G.H.; Tsoi K.K.F.; Sung J.J.Y.
  收藏 | 浏览/下载：32/0 | 提交时间：2022/01/18
Air quality Lung adenocarcinoma Lung cancer Lung squamous cell carcinoma Smoking |
| Computational Probing the Methylation Sites Related to EGFR Inhibitor-Responsive Genes 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7
作者: Yuan, Rui; Chen, Shilong; Wang, Yongcui
收藏 | 浏览/下载：22/0 | 提交时间：2022/04/28
GROWTH-FACTOR RECEPTOR CELL LUNG-CANCER DNA METHYLATION ACQUIRED-RESISTANCE MUTATIONS SENSITIVITY REGRESSION ERLOTINIB SELECTION PROMOTER |
| Reprogramming of ovarian granulosa cells by YAP1 leads to development of high-grade cancer with mesenchymal lineage and serous features 期刊论文
Science Bulletin, 2020, 卷号: 65, 期号: 15
作者: Lv X.; He C.; Huang C.; Hua G.; Chen X.; Timm B.K.; Maclin V.M.; Haggerty A.A.; Aust S.K.; Golden D.M.; Dave B.J.; Tseng Y.-A.; Chen L.; Wang H.; Chen P.; Klinkebiel D.L.; Karpf A.R.; Dong J.; Drapkin R.I.; Rueda B.R.; Davis J.S.; Wang C.
收藏 | 浏览/下载：11/0 | 提交时间：2021/09/01
Cell dedifferentiation Cell reprogramming Mesenchymal type of high grade serous cancer Ovarian granulosa cells The Hippo pathway YAP1 oncogene |
| Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者: Wilmes S.; Hafer M.; Vuorio J.; Tucker J.A.; Winkelmann H.; Löchte S.; Stanly T.A.; Pulgar Prieto K.D.; Poojari C.; Sharma V.; Richter C.P.; Kurre R.; Hubbard S.R.; Christopher Garcia K.; Moraga I.; Vattulainen I.; Hitchcock I.S.; Piehler J.
收藏 | 浏览/下载：47/0 | 提交时间：2020/07/28
cytokine receptor homodimer Janus kinase 2 ligand oncoprotein cancer enzyme enzyme activity membrane molecular analysis mutation protein activation analysis Article cell membrane computer model controlled study dimerization fluorescence microscopy gene mutation HeLa cell line molecular dynamics mutant oncogene priority journal protein domain protein interaction quantitative analysis signal transduction |
| Computing cancer's weak spots 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者: Khamsi R.
收藏 | 浏览/下载：46/0 | 提交时间：2020/07/28
ruxolitinib STAT3 protein antineoplastic agent transcription factor algorithm cancer computer simulation disease treatment drug development medicine Article cancer cell cancer radiotherapy enzyme inhibition gene activity gene expression regulation gene interaction gene mutation gene repression gene targeting human laboratory test malignant neoplasm molecular dynamics nonhuman oncologist priority journal RNA sequencing algorithm genetics mutation neoplasm personalized medicine procedures systems biology Algorithms Antineoplastic Agents Humans Mutation Neoplasms Precision Medicine Systems Biology Transcription Factors |
| Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者: Uckelmann H.J.; Kim S.M.; Wong E.M.; Hatton C.; Giovinazzo H.; Gadrey J.Y.; Krivtsov A.V.; Rücker F.G.; Döhner K.; McGeehan G.M.; Levine R.L.; Bullinger L.; Vassiliou G.S.; Armstrong S.A.
收藏 | 浏览/下载：36/0 | 提交时间：2020/07/28
antileukemic agent methionine unclassified drug vtp 50469 biological development cancer cell disease treatment mutation numerical model oral health acute myeloid leukemia animal cell animal experiment animal model antineoplastic activity Article cell proliferation cell self-renewal chromatin controlled study drug targeting gene gene mutation leukemia cell molecularly targeted therapy mouse mouse model nonhuman NPM1 gene preleukemia priority journal Mus |
| Single-cell transcriptional diversity is a hallmark of developmental potential 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者: Gulati G.S.; Sikandar S.S.; Wesche D.J.; Manjunath A.; Bharadwaj A.; Berger M.J.; Ilagan F.; Kuo A.H.; Hsieh R.W.; Cai S.; Zabala M.; Scheeren F.A.; Lobo N.A.; Qian D.; Yu F.B.; Dirbas F.M.; Clarke M.F.; Newman A.M.
收藏 | 浏览/下载：46/0 | 提交时间：2020/07/28
cell cell component developmental biology experimental study genetic analysis tumor Article breast cancer breast carcinogenesis carcinogenesis cell differentiation computer model embryonic stem cell gene expression genetic code genetic variability human in vivo study nonhuman phenotype priority journal scoring system single cell RNA seq upregulation |
| Mechanisms generating cancer genome complexity from a single cell division error 期刊论文
, 2020, 卷号: 368, 期号: 6488
作者: Umbreit N.T.; Zhang C.-Z.; Lynch L.D.; Blaine L.J.; Cheng A.M.; Tourdot R.; Sun L.; Almubarak H.F.; Judge K.; Mitchell T.J.; Spektor A.; Pellman D.
收藏 | 浏览/下载：15/0 | 提交时间：2020/07/28
myosin adenosine triphosphatase cancer chromosome detection method DNA error correction gene expression genome genomics mutation Article cell division cellular, subcellular and molecular biological phenomena and functions chromosome breakage chromosome breakage fusion bridge chromosome bridge formation chromosomes and chromosomal phenomena chromothripsis DNA damage DNA replication human interphase malignant neoplasm micronucleus mitosis oncogenomics priority journal single cell division error |
| Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice 期刊论文
, 2020, 卷号: 367, 期号: 6481
作者: Kimura I.; Miyamoto J.; Ohue-Kitano R.; Watanabe K.; Yamada T.; Onuki M.; Aoki R.; Isobe Y.; Kashihara D.; Inoue D.; Inaba A.; Takamura Y.; Taira S.; Kumaki S.; Watanabe M.; Ito M.; Nakagawa F.; Irie J.; Kakuta H.; Shinohara M.; Iwatsuki K.; Tsujimoto G.; Ohno H.; Arita M.; Itoh H.; Hase K.
收藏 | 浏览/下载：45/0 | 提交时间：2020/07/28
G protein coupled receptor G protein coupled receptor 41 G protein coupled receptor 43 glucagon like peptide 1 short chain fatty acid unclassified drug disease incidence experimental study female microbial community phenotype pregnancy rodent adult animal cell animal experiment animal model animal tissue Article C57BL 6 mouse cell differentiation controlled study developmental stage diet composition diet supplementation dietary exposure disease exacerbation disease predisposition embryo embryo development energy metabolism enteroendocrine cell female fiber intake germfree animal glucose intolerance high risk pregnancy hyperglycemia Institute for Cancer Research mouse insulin metabolism intestine flora lipid diet low fiber diet male maternal nutrition metabolic syndrome X mouse newborn nonhuman obesity pancreas islet beta cell phenotype pregnancy prenatal development priority journal progeny protein expression risk reduction Mus |
| Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者: Ebright R.Y.; Lee S.; Wittner B.S.; Niederhoffer K.L.; Nicholson B.T.; Bardia A.; Truesdell S.; Wiley D.F.; Wesley B.; Li S.; Mai A.; Aceto N.; Vincent-Jordan N.; Szabolcs A.; Chirn B.; Kreuzer J.; Comaills V.; Kalinich M.; Haas W.; Ting D.T.; Toner M.; Vasudevan S.; Haber D.A.; Maheswaran S.; Micalizzi D.S.
收藏 | 浏览/下载：55/0 | 提交时间：2020/07/28
CRISPR associated protein epidermal growth factor receptor 2 Ki 67 antigen ribosome protein ribosome RNA transcription factor E2F ribosome protein cancer cell gene expression genetic engineering protein RNA tumor animal experiment animal model animal tissue Article biogenesis bioluminescence breast cancer cell cycle progression cell cycle regulation cell proliferation circulating tumor cell controlled study enzyme activation epithelial mesenchymal transition gene expression profiling genetic transcription human human cell lung metastasis metastasis microfluidics mouse nonhuman overall survival phenotype priority journal progression free survival promoter region protein expression protein processing protein synthesis proteomics RNA sequence transcription regulation animal breast tumor cancer transplantation CRISPR Cas system female gene expression regulation genetics pathology sequence analysis tumor cell line tumor embolism Mus Animals Breast Neoplasms Cell Line, Tumor CRISPR-Cas Systems Female Gene Expression Regulation, Neoplastic Humans Mice Neoplasm Metastasis Neoplasm Transplantation Neoplastic Cells, Circulating Ribosomal Proteins Sequence Analysis, RNA |
