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The phosphatidylserine flippase beta-subunit Tmem30a is essential for normal insulin maturation and secretion 期刊论文
MOLECULAR THERAPY, 2021, 卷号: 29, 期号: 9
作者:  Yang, Yeming;  Sun, Kuanxiang;  Liu, Wenjing;  Li, Xiao;  Tian, Wanli;  Shuai, Ping;  Zhu, Xianjun
收藏  |  浏览/下载：28/0  |  提交时间：2022/04/28
PANCREATIC BETA-CELLS  FATTY LIVER-DISEASE  TRANS-GOLGI NETWORK  PHOSPHOLIPID TRANSLOCATION  ENDOPLASMIC-RETICULUM  PLASMA-MEMBRANE  CDC50 PROTEINS  OBESITY  ATPASE  GENE  
Membrane-proximal F-actin restricts local membrane protrusions and directs cell migration 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Bisaria A.;  Hayer A.;  Garbett D.;  Cohen D.;  Meyer T.
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/28
cell component  concentration (composition)  membrane  polymerization  protein  actin  green fluorescent protein  cell membrane  cell motion  cell polarity  cell surface  chemistry  genetics  human  metabolism  umbilical vein endothelial cell  Actins  Cell Membrane  Cell Movement  Cell Polarity  Cell Surface Extensions  Green Fluorescent Proteins  Human Umbilical Vein Endothelial Cells  Humans  
PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:  Wang Q.;  Boshoff H.I.M.;  Harrison J.R.;  Ray P.C.;  Green S.R.;  Wyatt P.G.;  Barry Iii C.E.
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/28
3,3 bis di(methylsulfonyl)propionamide  antiinfective agent  bacterial protein  glucose  glycerol  magnesium  phosphate  propionamide derivative  protein proline proline glutamate  protein proline proline glutamate 51  unclassified drug  amide  bacterial protein  lipid  phthiocerol dimycocerosate  propionamide  thiol derivative  cell component  chemical compound  membrane  mutation  protein  tuberculosis  antibiotic resistance  Article  bacterial cell  bacterial cell wall  bacterial growth  bacterial outer membrane  cell division  drug structure  Mycobacterium tuberculosis  nonhuman  nutrient uptake  priority journal  protein depletion  cell membrane  cell membrane permeability  chemistry  drug effect  gene deletion  genetics  metabolism  transport at the cellular level  Mycobacterium tuberculosis  Amides  Bacterial Proteins  Biological Transport  Cell Membrane  Cell Membrane Permeability  Drug Resistance, Bacterial  Gene Deletion  Glucose  Glycerol  Lipids  Mycobacterium tuberculosis  Sulfhydryl Compounds  
HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease 期刊论文
, 2020, 卷号: 369, 期号: 6500
作者:  Cook S.A.;  Comrie W.A.;  Poli M.C.;  Similuk M.;  Oler A.J.;  Faruqi A.J.;  Kuhns D.B.;  Yang S.;  Vargas-Hernández A.;  Carisey A.F.;  Fournier B.;  Anderson D.E.;  Price S.;  Smelkinson M.;  Abou Chahla W.;  Forbes L.R.;  Mace E.M.;  Cao T.N.;  Coban-Akdemir Z.H.;  Jhangiani S.N.;  Muzny D.M.;  Gibbs R.A.;  Lupski J.R.;  Orange J.S.;  Cuvelier G.D.E.;  Al Hassani M.;  Al Kaabi N.;  Al Yafei Z.;  Jyonouchi S.;  Raje N.;  Caldwell J.W.;  Huang Y.;  Burkhardt J.K.;  Latour S.;  Chen B.;  ElGhazali G.;  Rao V.K.;  Chinn I.K.;  Lenardo M.J.
收藏  |  浏览/下载：53/0  |  提交时间：2020/07/28
actin  adenosine diphosphate ribosylation factor 1  ARF1 protein, human  cytokine  mammalian target of rapamycin complex 2  membrane protein  NCKAP1L protein, human  WASF1 protein, human  WASF2 protein, human  WASF3 protein, human  Wiskott Aldrich syndrome protein  biosynthesis  CD4+ T lymphocyte  cell proliferation  chemistry  genetics  human  immune deficiency  immunology  lymphoproliferative disease  metabolism  pedigree  phosphorylation  physiology  Actins  ADP-Ribosylation Factor 1  CD4-Positive T-Lymphocytes  Cell Proliferation  Cytokines  Humans  Immunologic Deficiency Syndromes  Lymphoproliferative Disorders  Mechanistic Target of Rapamycin Complex 2  Membrane Proteins  Pedigree  Phosphorylation  Wiskott-Aldrich Syndrome Protein Family  
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance 期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:  ElTanbouly M.A.;  Zhao Y.;  Nowak E.;  Li J.;  Schaafsma E.;  Le Mercier I.;  Ceeraz S.;  Lines J.L.;  Peng C.;  Carriere C.;  Huang X.;  Day M.;  Koehn B.;  Lee S.W.;  Morales M.S.;  Hogquist K.A.;  Jameson S.C.;  Mueller D.;  Rothstein J.;  Blazar B.R.;  Cheng C.;  Noelle R.J.
收藏  |  浏览/下载：56/0  |  提交时间：2020/07/28
cell protein  interferon  kruppel like factor 2  T lymphocyte receptor  unclassified drug  V type immunoglobulin domain containing suppressor of T cell activation protein  B7 antigen  Dies1 protein, mouse  lymphocyte antigen receptor  membrane protein  monoclonal antibody  VSIR protein, human  biological development  cell  gene expression  heterogeneity  homeostasis  immune response  immunity  tolerance  acute graft versus host disease  animal cell  animal experiment  animal model  Article  CD4+ T lymphocyte  cell death  cell expansion  cell fate  cell heterogeneity  cell loss  cell survival  controlled study  female  gene  gene deletion  homeostasis  immunological tolerance  in vivo study  long term survival  male  mouse  nonhuman  phenotype  priority journal  protein expression  protein function  rheumatoid arthritis  RNA sequencing  systemic lupus erythematosus  T lymphocyte  T lymphocyte activation  T lymphocyte subpopulation  TCR gene  upregulation  VISTA gene  animal  C57BL mouse  genetics  immunological tolerance  immunology  knockout mouse  lymphocyte activation  physiology  T lymphocyte  Mus  Animals  Antibodies, Monoclonal  B7 Antigens  Lymphocyte Activation  Membrane Proteins  Mice  Mice, Inbred C57BL  Mice, Knockout  Peripheral Tolerance  Receptors, Antigen, T-Cell  T-Lymphocytes  
Structure of V-ATPase from the mammalian brain 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Abbas Y.M.;  Wu D.;  Bueler S.A.;  Robinson C.V.;  Rubinstein J.L.
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/28
adenosine triphosphatase  neurotransmitter  proton  renin  unclassified drug  vacuolar type adenosine triphosphatase  Atp6ap1 protein, rat  ATP6AP2 protein, rat  bacterial protein  biological marker  cell surface receptor  proton transporting adenosine triphosphate synthase  blood  brain  catalysis  catalyst  enzyme  enzyme activity  membrane  protein  Article  axon  blood pressure regulation  brain tissue  catalysis  chemical structure  cryoelectron microscopy  electrolyte balance  electron microscopy  human  hydrolysis  Legionella pneumophila  molecular docking  nerve cell  neurotransmitter uptake  nonhuman  priority journal  protein structure  signal transduction  Wnt signaling  yeast  animal  biocatalysis  brain  cell membrane  chemical model  chemistry  enzymology  protein domain  rat  renin angiotensin aldosterone system  Legionella pneumophila  Mammalia  Rattus  Animals  Bacterial Proteins  Biocatalysis  Biomarkers  Brain  Cell Membrane  Cryoelectron Microscopy  Models, Chemical  Protein Domains  Rats  Receptors, Cell Surface  Renin-Angiotensin System  Vacuolar Proton-Translocating ATPases  Wnt Signaling Pathway