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Population transcriptomics uncover the relative roles of positive selection and differential expression in Batrachium bungei adaptation to the Qinghai-Tibetan plateau 期刊论文
PLANT CELL REPORTS, 2023, 卷号: 42, 期号: 5
作者:  Yu, Xiaolei;  Wei, Pei;  Zhao, Shuqi;  Chen, Zhuyifu;  Li, Xinzhong;  Zhang, Wencai;  Liu, Chenlai;  Yang, Yujiao;  Li, Xiaoyan;  Liu, Xing
收藏  |  浏览/下载:6/0  |  提交时间:2024/03/01
Batrachium bungei  Population transcriptomics  Positive selection analysis  Differential expression analysis  Adaptation  Qinghai-Tibet plateau  
Comparative transcriptome analysis to identify genes involved in terpenoid biosynthesis in Agriophyllum squarrosum, a folk medicinal herb native to Asian temperature deserts 期刊论文
PLANT BIOTECHNOLOGY REPORTS, 2021, 卷号: 15, 期号: 3
作者:  Yin, Xiaoyue;  Yan, Xia;  Qian, Chaoju;  Zhou, Shanshan;  Fang, Tingzhou;  Fan, Xingke;  Gao, Yuan;  Chang, Yuxiao;  Yang, Jian;  Ma, Xiao-Fei
收藏  |  浏览/下载:33/0  |  提交时间:2022/04/28
RNA-SEQ DATA  CANDIDATE GENES  EXPRESSION ANALYSIS  SYNTHASE GENES  PATHWAYS  IDENTIFICATION  TRITERPENES  METABOLISM  TOLERANCE  DIVERSITY  
Human CNS barrier-forming organoids with cerebrospinal fluid production 期刊论文
, 2020, 卷号: 369, 期号: 6500
作者:  Pellegrini L.;  Bonfio C.;  Chadwick J.;  Begum F.;  Skehel M.;  Lancaster M.A.
收藏  |  浏览/下载:39/0  |  提交时间:2020/07/28
blood brain barrier  cell culture technique  cerebrospinal fluid  choroid plexus  gene expression profiling  human  metabolism  organoid  physiology  protein cerebrospinal fluid level  proteomics  single cell analysis  Blood-Brain Barrier  Cell Culture Techniques  Cerebrospinal Fluid  Cerebrospinal Fluid Proteins  Choroid Plexus  Gene Expression Profiling  Humans  Organoids  Proteomics  Single-Cell Analysis  
Circadian rhythms in the absence of the clock gene Bmal1 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:  Ray S.;  Valekunja U.K.;  Stangherlin A.;  Howell S.A.;  Snijders A.P.;  Damodaran G.;  Reddy A.B.
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/28
phosphoproteome  proteome  transcription factor ARNTL  transcription factor Ets  transcriptome  unclassified drug  cell component  circadian rhythm  gene  gene expression  genome  molecular analysis  animal experiment  animal tissue  Article  Bmal1 gene  circadian rhythm  controlled study  gene deletion  gene expression regulation  gene function  gene knockout  genotype  knockout mouse  light dark cycle  liver  mouse  nonhuman  oscillation  oxidation reduction potential  priority journal  RNA sequence  skin fibroblast  temperature  transcription regulation  Mammalia  Mus  
Single-cell transcriptional diversity is a hallmark of developmental potential 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者:  Gulati G.S.;  Sikandar S.S.;  Wesche D.J.;  Manjunath A.;  Bharadwaj A.;  Berger M.J.;  Ilagan F.;  Kuo A.H.;  Hsieh R.W.;  Cai S.;  Zabala M.;  Scheeren F.A.;  Lobo N.A.;  Qian D.;  Yu F.B.;  Dirbas F.M.;  Clarke M.F.;  Newman A.M.
收藏  |  浏览/下载:46/0  |  提交时间:2020/07/28
cell  cell component  developmental biology  experimental study  genetic analysis  tumor  Article  breast cancer  breast carcinogenesis  carcinogenesis  cell differentiation  computer model  embryonic stem cell  gene expression  genetic code  genetic variability  human  in vivo study  nonhuman  phenotype  priority journal  scoring system  single cell RNA seq  upregulation  
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking 期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:  Lepack A.E.;  Werner C.T.;  Stewart A.F.;  Fulton S.L.;  Zhong P.;  Farrelly L.A.;  Smith A.C.W.;  Ramakrishnan A.;  Lyu Y.;  Bastle R.M.;  Martin J.A.;  Mitra S.;  O'Connor R.M.;  Wang Z.-J.;  Molina H.;  Turecki G.;  Shen L.;  Yan Z.;  Calipari E.S.;  Dietz D.M.;  Kenny P.J.;  Maze I.
收藏  |  浏览/下载:48/0  |  提交时间:2020/07/28
amidase  dopamine  histone H3  histone transamidase  protein glutamine gamma glutamyltransferase 2  RNA  unclassified drug  brain  cell  chemical compound  chemical reaction  gene expression  genetic analysis  protein  action potential  amino acid substitution  amino terminal sequence  Article  cocaine dependence  controlled study  dopamine release  dopaminergic nerve cell  dopaminergic transmission  down regulation  drug seeking behavior  enzyme activity  gene expression  histone dopaminylation  histone modification  human  human tissue  hyperpolarization  in vitro study  motivation  nerve cell plasticity  nerve projection  neuropathology  nucleus accumbens  priority journal  protein expression  protein function  reward  RNA sequence  ventral tegmentum  Rattus  
Marching to another clock 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:  Brown S.A.;  Sato M.
收藏  |  浏览/下载:42/0  |  提交时间:2020/07/28
RNA  transcription factor ARNTL  transcription factor CLOCK  transcription factor Ets  brain  circadian rhythm  molecular analysis  physiological response  protein  animal cell  animal tissue  Article  binding site  cell metabolism  circadian rhythm  controlled study  feedback system  genetic transcription  molecular dynamics  mouse  nonhuman  oxidation reduction reaction  priority journal  protein analysis  protein binding  protein expression  protein function  RNA analysis  RNA transcription  RNA translation  suprachiasmatic nucleus  music  walking  Circadian Rhythm  Music  Walking  
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:  Ebright R.Y.;  Lee S.;  Wittner B.S.;  Niederhoffer K.L.;  Nicholson B.T.;  Bardia A.;  Truesdell S.;  Wiley D.F.;  Wesley B.;  Li S.;  Mai A.;  Aceto N.;  Vincent-Jordan N.;  Szabolcs A.;  Chirn B.;  Kreuzer J.;  Comaills V.;  Kalinich M.;  Haas W.;  Ting D.T.;  Toner M.;  Vasudevan S.;  Haber D.A.;  Maheswaran S.;  Micalizzi D.S.
收藏  |  浏览/下载:55/0  |  提交时间:2020/07/28
CRISPR associated protein  epidermal growth factor receptor 2  Ki 67 antigen  ribosome protein  ribosome RNA  transcription factor E2F  ribosome protein  cancer  cell  gene expression  genetic engineering  protein  RNA  tumor  animal experiment  animal model  animal tissue  Article  biogenesis  bioluminescence  breast cancer  cell cycle progression  cell cycle regulation  cell proliferation  circulating tumor cell  controlled study  enzyme activation  epithelial mesenchymal transition  gene expression profiling  genetic transcription  human  human cell  lung metastasis  metastasis  microfluidics  mouse  nonhuman  overall survival  phenotype  priority journal  progression free survival  promoter region  protein expression  protein processing  protein synthesis  proteomics  RNA sequence  transcription regulation  animal  breast tumor  cancer transplantation  CRISPR Cas system  female  gene expression regulation  genetics  pathology  sequence analysis  tumor cell line  tumor embolism  Mus  Animals  Breast Neoplasms  Cell Line, Tumor  CRISPR-Cas Systems  Female  Gene Expression Regulation, Neoplastic  Humans  Mice  Neoplasm Metastasis  Neoplasm Transplantation  Neoplastic Cells, Circulating  Ribosomal Proteins  Sequence Analysis, RNA  
The evolutionary dynamics and fitness landscape of clonal hematopoiesis 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:  Watson C.J.;  Papula A.L.;  Poon G.Y.P.;  Wong W.H.;  Young A.L.;  Druley T.E.;  Fisher D.S.;  Blundell J.R.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
DNA methyltransferase 3A  blood  cancer  evolutionary biology  fitness  gene expression  genetic drift  hematology  mutation  pathogenicity  acute myeloid leukemia  age distribution  allele  Article  cancer risk  cell expansion  cell population  clonal hematopoiesis  epigenetics  gene mutation  genetic variability  hematological parameters  hematopoiesis  hematopoietic stem cell  human  molecular evolution  mutational analysis  nonhuman  priority journal  single nucleotide polymorphism  somatic mutation  stem cell self-renewal  
Structure of nucleosome-bound human BAF complex 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  He S.;  Wu Z.;  Tian Y.;  Yu Z.;  Yu J.;  Wang X.;  Li J.;  Liu B.;  Xu Y.
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/28
actin related protein  adenosine triphosphatase  BRG1 BRM associated factor  DNA  multiprotein complex  protein SWI  retinoblastoma binding protein 2  SMARCC protein  SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily B member 1  transcription factor  transcription factor SNF  unclassified drug  cancer  enzyme activity  gene expression  hydrolysis  mutation  protein  alpha helix  Article  carboxy terminal sequence  cell interaction  cryoelectron microscopy  disease association  human  malignant neoplasm  molecular recognition  mutation  nucleosome  priority journal  protein function  protein hydrolysis  protein structure  structure analysis  Mammalia