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Structure of the RNA-dependent RNA polymerase from COVID-19 virus 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Gao Y.;  Yan L.;  Huang Y.;  Liu F.;  Zhao Y.;  Cao L.;  Wang T.;  Sun Q.;  Ming Z.;  Zhang L.;  Ge J.;  Zheng L.;  Zhang Y.;  Wang H.;  Zhu Y.;  Zhu C.;  Hu T.;  Hua T.;  Zhang B.;  Yang X.;  Li J.;  Yang H.;  Liu Z.;  Xu W.;  Guddat L.W.;  Wang Q.;  Lou Z.;  Rao Z.
收藏  |  浏览/下载:40/0  |  提交时间:2020/07/28
comparative study  drug  electron microscopy  enzyme  enzyme activity  RNA  virus  Coronavirus  SARS coronavirus  adenosine phosphate  alanine  antivirus agent  NSP7 protein, SARS-CoV-2  NSP8 protein, SARS-CoV-2  remdesivir  RNA directed RNA polymerase  RNA-dependent RNA polymerase, coronavirus  viral protein  beta sheet  Betacoronavirus  chemistry  cryoelectron microscopy  drug design  enzyme active site  enzymology  metabolism  molecular model  protein domain  ultrastructure  Adenosine Monophosphate  Alanine  Antiviral Agents  Betacoronavirus  Catalytic Domain  Cryoelectron Microscopy  Drug Design  Models, Molecular  Protein Conformation, beta-Strand  Protein Domains  RNA Replicase  Viral Nonstructural Proteins  
Giant thermopower of ionic gelatin near room temperature 期刊论文
, 2020, 卷号: 368, 期号: 6495
作者:  Han C.-G.;  Qian X.;  Li Q.;  Deng B.;  Zhu Y.;  Han Z.;  Zhang W.;  Wang W.;  Feng S.-P.;  Chen G.;  Liu W.
收藏  |  浏览/下载:44/0  |  提交时间:2020/07/28
detection method  electricity  equipment  Internet  temperature effect  thermal power  
A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:  Wu Y.;  Wang F.;  Shen C.;  Peng W.;  Li D.;  Zhao C.;  Li Z.;  Li S.;  Bi Y.;  Yang Y.;  Gong Y.;  Xiao H.;  Fan Z.;  Tan S.;  Wu G.;  Tan W.;  Lu X.;  Fan C.;  Wang Q.;  Liu Y.;  Zhang C.;  Qi J.;  Gao G.F.;  Gao F.;  Liu L.
收藏  |  浏览/下载:29/0  |  提交时间:2020/07/28
Coronavirus  angiotensin converting enzyme 2  coronavirus spike glycoprotein  dipeptidyl carboxypeptidase  epitope  monoclonal antibody  neutralizing antibody  virus antibody  virus receptor  animal  chemistry  Coronavirus infection  disease model  human  immunology  isolation and purification  lung  mouse  pandemic  protein domain  serodiagnosis  virology  virus load  virus pneumonia  Animals  Antibodies, Monoclonal  Antibodies, Neutralizing  Antibodies, Viral  Coronavirus Infections  Disease Models, Animal  Humans  Immunodominant Epitopes  Lung  Mice  Neutralization Tests  Pandemics  Peptidyl-Dipeptidase A  Pneumonia, Viral  Protein Domains  Receptors, Virus  Spike Glycoprotein, Coronavirus  Viral Load  
Disassembling 2D van der Waals crystals into macroscopic monolayers and reassembling into artificial lattices 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Liu F.;  Wu W.;  Bai Y.;  Chae S.H.;  Li Q.;  Wang J.;  Hone J.;  Zhu X.-Y.
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/28
chemical compound  transition metal dichalcogenide  unclassified drug  chemical bonding  crystal chemistry  layer  symmetry  transition element  two-dimensional modeling  Article  broken inversion symmetry  bulk crystal size  chemical procedures  chemical structure  complex formation  controlled study  crystal  crystal monolayer  crystal structure  high throughput analysis  histogram  image analysis  particle size  physical parameters  priority journal  quality control  Scotch tape exfoliation  two dimensional structure  van der Waals crystal  
Enhanced sustainable green revolution yield via nitrogen-responsive chromatin modulation in rice 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Wu K.;  Wang S.;  Song W.;  Zhang J.;  Wang Y.;  Liu Q.;  Yu J.;  Ye Y.;  Li S.;  Chen J.;  Zhao Y.;  Wang J.;  Wu X.;  Wang M.;  Zhang Y.;  Liu B.;  Wu Y.;  Harberd N.P.;  Fu X.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
DELLA protein  gibberellin  gibberellin insensitive dwarf1  histone H3  polycomb repressive complex 2  receptor  transcription factor  unclassified drug  alternative agriculture  chromosome  gene expression  genetic engineering  green revolution  inhibition  molecular analysis  nitrogen  nutrient use efficiency  protein  rice  agriculture  allele  Article  chromatin immunoprecipitation  controlled study  D14 gene  gene mutation  genetic screening  genetic transcription  grain yield  green revolution  histone modification  modulation  ngr5 gene  nitrogen availability  nitrogen responsive chromatin modulation  nonhuman  OsSPL14 gene  plant gene  polymerase chain reaction  priority journal  protein protein interaction  rice  RNA sequencing  varietas  
Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Neubarth N.L.;  Emanuel A.J.;  Liu Y.;  Springel M.W.;  Handler A.;  Zhang Q.;  Lehnert B.P.;  Guo C.;  Orefice L.L.;  Abdelaziz A.;  DeLisle M.M.;  Iskols M.;  Rhyins J.;  Kim S.J.;  Cattel S.J.;  Regehr W.;  Harvey C.D.;  Drugowitsch J.;  Ginty D.D.
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28
chemical cue  mechanoreception  perception  reaction kinetics  skin  visual cue  Mammalia  Mus  Bdnf protein, mouse  brain derived neurotrophic factor  membrane protein  Ntrk2 protein, mouse  protein tyrosine kinase  animal  C57BL mouse  electron microscopy  epidermis  female  genetics  innervation  knockout mouse  male  Merkel cell  metabolism  mouse  physiology  signal transduction  touch  ultrastructure  Animals  Brain-Derived Neurotrophic Factor  Epidermis  Female  Male  Membrane Glycoproteins  Merkel Cells  Mice  Mice, Inbred C57BL  Mice, Knockout  Microscopy, Electron  Protein-Tyrosine Kinases  Signal Transduction  Touch  Touch Perception