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Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 10
作者:  Tsai P.-Y.;  Lee M.-S.;  Jadhav U.;  Naqvi I.;  Madha S.;  Adler A.;  Mistry M.;  Naumenko S.;  Lewis C.A.;  Hitchcock D.S.;  Roberts F.R.;  DelNero P.;  Hank T.;  Honselmann K.C.;  Oyarvide V.M.;  Mino-Kenudson M.;  Clish C.B.;  Shivdasani R.A.;  Kalaany N.Y.
收藏  |  浏览/下载:32/0  |  提交时间:2021/05/24
Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 10
作者:  Whitworth L.J.;  Troll R.;  Pagán A.J.;  Roca F.J.;  Edelstein P.H.;  Troll M.;  Tobin D.M.;  Phu N.H.;  Bang N.D.;  Thwaites G.E.;  Thuong Thuong N.T.;  Sewell R.F.;  Ramakrishnan L.
收藏  |  浏览/下载:14/0  |  提交时间:2021/05/24
Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 45
作者:  Ho W.W.;  Gomes-Santos I.L.;  Aoki S.;  Datta M.;  Kawaguchi K.;  Talele N.P.;  Roberge S.;  Ren J.;  Liu H.;  Chen I.X.;  Andersson P.;  Chatterjee S.;  Kumar A.S.;  Amoozgar Z.;  Zhang Q.;  Huang P.;  Ng M.R.;  Chauhan V.P.;  Xu L.;  Duda D.G.;  Clark J.W.;  Pittet M.J.;  Fukumura D.;  Jain R.K.
收藏  |  浏览/下载:44/0  |  提交时间:2021/11/25
Computational modeling of ovarian cancer dynamics suggests optimal strategies for therapy and screening 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 25
作者:  Gu S.;  Lheureux S.;  Sayad A.;  Cybulska P.;  Hogen L.;  Vyarvelska I.;  Tu D.;  Parulekar W.R.;  Nankivell M.;  Kehoe S.;  Chi D.S.;  Levine D.A.;  Bernardini M.Q.;  Rosen B.;  Oza A.;  Brown M.;  Neel B.G.
收藏  |  浏览/下载:37/0  |  提交时间:2021/11/25
Critical role of the CD44lowCD62Llow CD8+ T cell subset in restoring antitumor immunity in aged mice 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 23
作者:  Nakajima Y.;  Chamoto K.;  Oura T.;  Honjo T.
收藏  |  浏览/下载:21/0  |  提交时间:2021/11/25
Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 17
作者:  Saavedra-García P.;  Roman-Trufero M.;  Al-Sadah H.A.;  Blighe K.;  López-Jiménez E.;  Christoforou M.;  Penfold L.;  Capece D.;  Xiong X.;  Miao Y.;  Parzych K.;  Caputo V.S.;  Siskos A.P.;  Encheva V.;  Liu Z.;  Thiel D.;  Kaiser M.F.;  Piazza P.;  Chaidos A.;  Karadimitris A.;  Franzoso G.;  Snijders A.P.;  Keun H.C.;  Oyarzún D.A.;  Barahona M.;  Auner H.W.
收藏  |  浏览/下载:29/0  |  提交时间:2021/05/24
Polypeptide nanoformulation-induced immunogenic cell death and remission of immunosuppression for enhanced chemoimmunotherapy 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 4
作者:  Feng X.;  Xu W.;  Liu J.;  Li D.;  Li G.;  Ding J.;  Chen X.
收藏  |  浏览/下载:22/0  |  提交时间:2021/09/01
Chemoimmunotherapy  Controlled drug release  Immunogenic cell death  Polypeptide nanogel  Remission of Immunosuppression  
Nanomedicine enables autophagy-enhanced cancer-cell ferroptosis 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 5
作者:  Yang J.;  Ding L.;  Yu L.;  Wang Y.;  Ge M.;  Jiang Q.;  Chen Y.
收藏  |  浏览/下载:27/0  |  提交时间:2021/09/01
Autophagy  Ferroptosis  Manganese oxide  Mesoporous silica  Trehalose  Tumor therapy  
Tiny 2D silicon quantum sheets: a brain photonic nanoagent for orthotopic glioma theranostics 期刊论文
Science Bulletin, 2021, 卷号: 66, 期号: 2
作者:  Miao Z.;  Hu D.;  Gao D.;  Fan L.;  Ma Y.;  Ma T.;  Liu X.;  Zheng H.;  Zha Z.;  Sheng Z.;  Xu C.-Y.
收藏  |  浏览/下载:27/0  |  提交时间:2021/09/01
Orthotopic glioma  Photoacoustic imaging  Photothermal therapy  Theranostic agents  Two-dimensional (2D) silicon  
A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 13
作者:  Xu L.;  Yin Y.;  Li Y.;  Chen X.;  Chang Y.;  Zhang H.;  Liu J.;  Beasley J.;  McCaw P.;  Zhang H.;  Young S.;  Groth J.;  Wang Q.;  Locasale J.W.;  Gao X.;  Tang D.G.;  Dong X.;  He Y.;  George D.;  Hu H.;  Huang J.
收藏  |  浏览/下载:30/0  |  提交时间:2021/05/24