已选(0)清除
条数/页: 排序方式: |
| Plant breeding advancements with CRISPR-Cas genome editing technologies will assist future food security 期刊论文 FRONTIERS IN PLANT SCIENCE, 2023, 卷号: 14 作者: Ahmad, M. 收藏  |  浏览/下载:1/0  |  提交时间:2024/01/31 |
| Cross-talk of insulin-like peptides, juvenile hormone, and 20-hydroxyecdysone in regulation of metabolism in the mosquito aedes aegypti 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 6 作者: Ling L.; Raikhel A.S. 收藏  |  浏览/下载:29/0  |  提交时间:2021/05/24 |
| Loss of function of a DMR6 ortholog in tomato confers broad-spectrum disease resistance 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 27 作者: de Toledo Thomazella D.P.; Seong K.; Mackelprang R.; Dahlbeck D.; Geng Y.; Gill U.S.; Qi T.; Pham J.; Giuseppe P.; Lee C.Y.; Ortega A.; Cho M.-J.; Hutton S.F.; Staskawicz B. 收藏  |  浏览/下载:48/0  |  提交时间:2022/02/22 |
| Gene drive that results in addiction to a temperature-sensitive version of an essential gene triggers population collapse in Drosophila 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 49 作者: Oberhofer G.; Ivy T.; Hay B.A. 收藏  |  浏览/下载:21/0  |  提交时间:2022/02/22 |
| Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment 期刊论文 Science, 2021, 卷号: 371, 期号: 6530 作者: Trujillo C.A.; Rice E.S.; Schaefer N.K.; Chaim I.A.; Wheeler E.C.; Madrigal A.A.; Buchanan J.; Preissl S.; Wang A.; Negraes P.D.; Szeto R.A.; Herai R.H.; Huseynov A.; Ferraz M.S.A.; Borges F.S.; Kihara A.H.; Byrne A.; Marin M.; Vollmers C.; Brooks A.N.; Lautz J.D.; Semendeferi K.; Shapiro B.; Yeo G.W.; Smith S.E.P.; Green R.E.; Muotri A.R. 收藏  |  浏览/下载:35/0  |  提交时间:2022/01/14 |
| Knockout of the HMG domain of the porcine SRY gene causes sex reversal in gene-edited pigs 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 2 作者: Kurtz S.; Lucas-Hahn A.; Schlegelberger B.; Göhring G.; Niemann H.; Mettenleiter T.C.; Petersen B. 收藏  |  浏览/下载:37/0  |  提交时间:2021/05/24 |
| Real-time observation of cas9 postcatalytic domain motions 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 2 作者: Wang Y.; Mallon J.; Wang H.; Singh D.; Jo M.H.; Hua B.; Bailey S.; Ha T. 收藏  |  浏览/下载:31/0  |  提交时间:2021/05/24 |
| Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants 期刊论文 , 2020, 卷号: 368, 期号: 6488 作者: Walton R.T.; Christie K.A.; Whittaker M.N.; Kleinstiver B.P. 收藏  |  浏览/下载:16/0  |  提交时间:2020/07/28 adenine adenosine CRISPR associated endonuclease Cas9 cytosine guanosine SpG protein SpRY nuclease thymine unclassified drug Cas9 endonuclease Streptococcus pyogenes bacterium enzyme activity genetic engineering genetic variation genome Article CRISPR-CAS9 system DNA sequence enzyme activity gene editing gene targeting genetic variability human mutagenesis nonhuman priority journal protein engineering protein motif protein structure protospacer adjacent motif Streptococcus pyogenes chemistry CRISPR Cas system enzyme specificity gene editing gene targeting genetic predisposition genetics HEK293 cell line procedures protein domain Streptococcus pyogenes CRISPR-Associated Protein 9 CRISPR-Cas Systems Gene Editing Gene Targeting Genetic Predisposition to Disease HEK293 Cells Humans Mutagenesis Protein Domains Substrate Specificity |
| Very fast CRISPR on demand 期刊论文 , 2020, 卷号: 368, 期号: 6496 作者: Liu Y.; Zou R.S.; He S.; Nihongaki Y.; Li X.; Razavi S.; Wu B.; Ha T. 收藏  |  浏览/下载:20/0  |  提交时间:2020/07/28 Cas9 endonuclease Streptococcus pyogenes double strand break repair protein MRE11 H2AX protein, human histone MRE11 protein, human CRISPR Cas system DNA cleavage DNA repair double stranded DNA break fluorescence imaging gene editing genetics HEK293 cell line human light metabolism phosphorylation procedures radiation response single cell analysis CRISPR-Associated Protein 9 CRISPR-Cas Systems DNA Breaks, Double-Stranded DNA Cleavage DNA Repair Gene Editing HEK293 Cells Histones Humans Light MRE11 Homologue Protein Optical Imaging Phosphorylation Single-Cell Analysis |
| Reduced thermal tolerance in a coral carrying CRISPR-induced mutations in the gene for a heat-shock transcription factor 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2020, 卷号: 117, 期号: 46 作者: Cleves P.A.; Tinoco A.I.; Bradford J.; Perrin D.; Bay L.K.; Pringle J.R. 收藏  |  浏览/下载:22/0  |  提交时间:2021/01/06 |