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VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance 期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:  ElTanbouly M.A.;  Zhao Y.;  Nowak E.;  Li J.;  Schaafsma E.;  Le Mercier I.;  Ceeraz S.;  Lines J.L.;  Peng C.;  Carriere C.;  Huang X.;  Day M.;  Koehn B.;  Lee S.W.;  Morales M.S.;  Hogquist K.A.;  Jameson S.C.;  Mueller D.;  Rothstein J.;  Blazar B.R.;  Cheng C.;  Noelle R.J.
收藏  |  浏览/下载:48/0  |  提交时间:2020/07/28
cell protein  interferon  kruppel like factor 2  T lymphocyte receptor  unclassified drug  V type immunoglobulin domain containing suppressor of T cell activation protein  B7 antigen  Dies1 protein, mouse  lymphocyte antigen receptor  membrane protein  monoclonal antibody  VSIR protein, human  biological development  cell  gene expression  heterogeneity  homeostasis  immune response  immunity  tolerance  acute graft versus host disease  animal cell  animal experiment  animal model  Article  CD4+ T lymphocyte  cell death  cell expansion  cell fate  cell heterogeneity  cell loss  cell survival  controlled study  female  gene  gene deletion  homeostasis  immunological tolerance  in vivo study  long term survival  male  mouse  nonhuman  phenotype  priority journal  protein expression  protein function  rheumatoid arthritis  RNA sequencing  systemic lupus erythematosus  T lymphocyte  T lymphocyte activation  T lymphocyte subpopulation  TCR gene  upregulation  VISTA gene  animal  C57BL mouse  genetics  immunological tolerance  immunology  knockout mouse  lymphocyte activation  physiology  T lymphocyte  Mus  Animals  Antibodies, Monoclonal  B7 Antigens  Lymphocyte Activation  Membrane Proteins  Mice  Mice, Inbred C57BL  Mice, Knockout  Peripheral Tolerance  Receptors, Antigen, T-Cell  T-Lymphocytes  
A cell atlas of human thymic development defines T cell repertoire formation 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Park J.-E.;  Botting R.A.;  Conde C.D.;  Popescu D.-M.;  Lavaert M.;  Kunz D.J.;  Goh I.;  Stephenson E.;  Ragazzini R.;  Tuck E.;  Wilbrey-Clark A.;  Roberts K.;  Kedlian V.R.;  Ferdinand J.R.;  He X.;  Webb S.;  Maunder D.;  Vandamme N.;  Mahbubani K.T.;  Polanski K.;  Mamanova L.;  Bolt L.;  Crossland D.;  De Rita F.;  Fuller A.;  Filby A.;  Reynolds G.;  Dixon D.;  Saeb-Parsy K.;  Lisgo S.;  Henderson D.;  Vento-Tormo R.;  Bayraktar O.A.;  Barker R.A.;  Meyer K.B.;  Saeys Y.;  Bonfanti P.;  Behjati S.;  Clatworthy M.R.;  Taghon T.;  Haniffa M.;  Teichmann S.A.
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T lymphocyte receptor  cell component  developmental biology  differentiation  genomics  recombination  RNA  adaptive immunity  Article  CD4+ T lymphocyte  CD8+ T lymphocyte  cell fate  cell maturation  cell selection  controlled study  developmental stage  gene  gene expression  gene expression profiling  GNG4 gene  human  human cell  human tissue  lymphocyte differentiation  priority journal  protein expression  regulatory T lymphocyte  RNA sequencing  sequence analysis  T lymphocyte  T lymphocyte activation  thymic medulla  thymocyte  thymus  XCL1 gene  
Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者:  Wang J.;  Li P.;  Yu Y.;  Fu Y.;  Jiang H.;  Lu M.;  Sun Z.;  Jiang S.;  Lu L.;  Wu M.X.
收藏  |  浏览/下载:33/0  |  提交时间:2020/07/28
2',3' cyclic guanosine monophosphate adenosine monophosphate  influenza vaccine  interferon  nanoparticle  pulmonary surfactant biomimetic nanoparticle  purine nucleotide  surfactant protein A  surfactant protein D  unclassified drug  cell  drug resistance  immune response  immunity  induced response  influenza  nanoparticle  rodent  surfactant  vaccine  animal cell  animal experiment  animal model  animal tissue  Article  CD8+ T lymphocyte  cellular immunity  controlled study  cross protection  cytokine response  drug efficacy  drug safety  drug synthesis  female  human  humoral immunity  hydrophilicity  immune response  immunopathology  immunosurveillance  influenza  innate immunity  lung alveolus epithelium cell  lung alveolus macrophage  mouse  Mustela putorius furo  nanoencapsulation  nonhuman  priority journal  Mus  Mustela  
Cultivating fungal research 期刊论文
, 2020, 卷号: 368, 期号: 6489
作者:  Kong H.H.;  Segre J.A.
收藏  |  浏览/下载:62/0  |  提交时间:2020/07/28
amphotericin B  dectin 1  echinocandin  fluconazole  interleukin 17  bacterium  fungal disease  fungus  immune system  mutualism  pathogen  antifungal resistance  Article  autoimmune disease  bloodstream infection  Candida albicans  Candida auris  CD4+ T lymphocyte  commensalism  fungal colonization  fungus transmission  host fungus interaction  immune deficiency  interferon production  multidrug resistance  mycosis  nonhuman  opportunistic infection  pancreas adenocarcinoma  priority journal  Th17 cell  
Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Rougé L.;  Chiang N.;  Steffek M.;  Kugel C.;  Croll T.I.;  Tam C.;  Estevez A.;  Arthur C.P.;  Koth C.M.;  Ciferri C.;  Kraft E.;  Payandeh J.;  Nakamura G.;  Koerber J.T.;  Rohou A.
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/28
CD20 antigen  dimer  epitope  Fc receptor  immunoglobulin F(ab) fragment  obinutuzumab  ocrelizumab  ofatumumab  rituximab  tositumomab i 131  antibody  antigen  cell  chemical binding  composite  gene expression  genetic marker  protein  amino acid sequence  antibody dependent cellular cytotoxicity  antigen antibody complex  antigen binding  antigen structure  Article  cell death  cell surface  chemical bond  complement dependent cytotoxicity  drug protein binding  drug targeting  electron microscopy  human  humoral immune deficiency  insect cell  lipid raft  malignant neoplasm  molecular recognition  multiple sclerosis  nonhuman  phagocytosis  priority journal  protein cross linking  protein interaction  stoichiometry  surface plasmon resonance  
MRNA destabilization by BTG1 and BTG2 maintains T cell quiescence 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Hwang S.S.;  Lim J.;  Yu Z.;  Kong P.;  Sefik E.;  Xu H.;  Harman C.C.D.;  Kim L.K.;  Lee G.R.;  Li H.-B.;  Flavell R.A.
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/28
CD69 antigen  chemokine receptor CCR7  epidermal growth factor receptor 2  Hermes antigen  interleukin 2 receptor alpha  interleukin 2 receptor gamma  interleukin 7 receptor  kruppel like factor 2  messenger RNA  polyadenylic acid  T lymphocyte receptor  transcription factor FKHR  transcriptome  biodegradation  cell component  RNA  adenylation  Article  BTG1 gene  BTG2 gene  Ccr7 gene  CD4+ T lymphocyte  CD8+ T lymphocyte  cell differentiation  cell expansion  cell maturation  cell migration  cell proliferation  cell size  cell specificity  cell survival  controlled study  CRISPR-CAS9 system  flow cytometry  gene  gene control  gene expression  gene function  gene identification  immunoprecipitation  in vitro study  in vivo study  memory T lymphocyte  nonhuman  phylogenetic tree  priority journal  RNA degradation  RNA sequencing  S1pr1 gene  Sell gene  spleen  T lymphocyte  T lymphocyte activation  tail length (comet assay)  thymus  upregulation  
Microglia mediate forgetting via complement-dependent synaptic elimination 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Wang C.;  Yue H.;  Hu Z.;  Shen Y.;  Ma J.;  Li J.;  Wang X.-D.;  Wang L.;  Sun B.;  Shi P.;  Wang L.;  Gu Y.
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/28
complement  complement component C1q  complement component C3  complement receptor  decay accelerating factor  adult  cell  inhibition  memory  nervous system  adult  aging  animal cell  animal experiment  Article  C57BL 6 mouse  cognition  controlled study  functional dissociation  hippocampus  memory  memory consolidation  microglia  mouse  nerve cell inhibition  nerve cell plasticity  nervous system development  nonhuman  phagocytosis  priority journal  synaptic inhibition  Mus